id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-006714-q7wy76e2	Delannoy, P.-Y.	Impact of combination therapy with aminoglycosides on the outcome of ICU-acquired bacteraemias	2012-02-15		.txt	text/plain	2878	173	43	Our study supports the hypothesis that combination short-term antibiotherapy with an aminoglycoside for ICU-acquired bacteraemias could increase survival. Meta-analysis failed to demonstrate improved outcomes in patients treated with antibiotic combinations over those receiving monotherapy [1] [2] [3] [4] and resulted in a decreased use of combination therapy. We performed a retrospective study to evaluate the impact of AGs in antimicrobial combination on ICU-acquired bacteraemia in our universityaffiliated ICU [8] [9] [10] [11] . The aim of the study was to evaluate the impact of AGs in antibiotic combination on the outcome of patients with ICU-acquired bacteraemia. We found a survival benefit with the use of combination therapy with AGs for ICU-acquired bacteraemias. In the ICU, inadequate empirical antibiotic therapy is associated with an increased mortality risk in patients with ventilator-associated pneumonia and bacteraemia. Our study suggests that short-term combination beta-lactams plus AGs therapy in intensive care unit (ICU)-acquired bacteraemia could reduce mortality.	./cache/cord-006714-q7wy76e2.txt	./txt/cord-006714-q7wy76e2.txt