id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-007833-wkv808ix	Modi, Dipenkumar	Pomalidomide-Induced Pulmonary Toxicity in Multiple Myeloma	2015-12-16		.txt	text/plain	1338	101	44	In this article, the authors report an additional case of pomalidomide-induced pulmonary toxicity based on temporal relationship between drug administration and onset of symptoms as well as characteristic imaging findings. Lenalidomide and bortezomib were discontinued, and he was initiated on pomalidomide 4 mg/d, days 1 through 21 with dexamethasone 20 mg once weekly. Approximately 8 months after starting treatment with pomalidomide, the patient developed fever, progressive dyspnea, productive cough, and generalized weakness for 5 days duration before presenting to the hospital. The patient's recurrence and resolution of symptoms in a temporal relationship to therapy with pomalidomide, along with ground glass opacities on CT, led to a strong suspicion of pomalidomide-induced pulmonary toxicity. 3, 4 Pulmonary toxicity is an uncommon but increasingly reported clinical complication of IMiD agents, particularly thalidomide and lenalidomide. Usual time interval between initiation of treatment to onset of symptoms is 8 to 120 days, but toxicity from pomalidomide may be delayed.	./cache/cord-007833-wkv808ix.txt	./txt/cord-007833-wkv808ix.txt