id author title date pages extension mime words sentences flesch summary cache txt cord-009417-458rrhcm Luce, Judith A. Use of Blood Components in the Intensive Care Unit 2009-05-15 .txt text/plain 17101 918 43 Benefi ts to the patient with more judicious use of platelet transfusion include decreased donor exposure, which lessens the risk of transfusion-transmitted disease; fewer febrile and allergic reactions that may complicate the hospital course; and the potential delay or prevention of alloimmunization to HLA and platelet antigens. If anti-IgA antibodies are determined to be the cause of this reaction, the patient must receive blood components donated by IgA-defi cient individuals or, if unavailable, specially prepared washed RBCs and platelet concentrates. These patients may have intensive red cell and platelet transfusion requirements and need specialized products such as CMV-negative and irradiated blood components. A blood bank problem uniquely encountered in BMT is the need to switch the patient's ABO group because of an ABO-mismatched transplant, thus necessitating an exchange transfusion of red cells and plasma-containing products (i.e., platelet concentrates) of differing ABO type to avoid hemolysis of donor and recipient cells. ./cache/cord-009417-458rrhcm.txt ./txt/cord-009417-458rrhcm.txt