id author title date pages extension mime words sentences flesch summary cache txt cord-009697-dq4y89ab Yuen, Eddie Role of absolute lymphocyte count in the screening of patients with suspected SARS 2003-07-25 .txt text/plain 1510 92 59 3 This multicentre, placebo-controlled, randomized, double-blind trial in 6213 patients with acute ST-elevation myocardial infarct (STEMI) found that magnesium sulphate, (2 g intravenous bolus over 15 min followed by a 17 g infusion over 24 h), administered within 6 hours of onset of symptoms did not have any effect on the primary end-point of 30 day all-cause mortality when compared with placebo (15.3% 30 day mortality in the magnesium group vs 15.2% in the placebo group; odds ratio 1.0; 95% CI 0.9-1.2; P = 0.96). As the investigators point out in the discussion of their paper, this means that 68 684 patients have been studied over the past 22 years in 14 randomized trials of magnesium in myocardial infarction. Second, a multicentre, placebo-controlled, randomized, double-blind trial of intravenous magnesium sulphate in 248 patients with acute severe asthma was recently reported. ./cache/cord-009697-dq4y89ab.txt ./txt/cord-009697-dq4y89ab.txt