id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-011093-d9dbvbcy	Orange, Jordan S.	How I Manage Natural Killer Cell Deficiency	2019-11-22		.txt	text/plain	8253	339	45	Natural killer (NK) cell deficiency (NKD) is a subset of primary immunodeficiency disorders (PID) in which an abnormality of NK cells represents a major immunological defect resulting in the patient's clinical immunodeficiency. In order to be as clear as possible: NKD is a subset of PID in which the NK cell abnormality represents the major immunological defect resulting in the clinical immunodeficiency. As delineated above an example of this broader subset of PIDs that include an impact upon NK cells is NK -SCID, where the lack of NK cells is potentially relevant but not the major immunological defect causing clinical immunodeficiency. That said, to be an NKD, again the NK cell abnormality must represent the primary immunological defect presumably leading to the patient's clinical immunodeficiency. A patient with a known PID who also has abnormal NK cell numbers or functional tests should similarly not be labeled as having an NKD.	./cache/cord-011093-d9dbvbcy.txt	./txt/cord-011093-d9dbvbcy.txt