id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-018834-4ligp4ak	Farag, Ehab	The Perioperative Use of Albumin	2016-06-23		.txt	text/plain	7554	379	43	HSA is the most important antioxidant capacity of human plasma, in addition to its ability to protect the body from the harmful effects of heavy metals such as iron and copper and reduce their ability to produce reactive oxygen radicals. Recently, its use has been questioned following a widely publicized meta-analysis in 1998 that reported increased mortality in patients who received albumin solutions; the role of albumin administration in critically ill patients became highly controversial. However, the results of this meta-analysis have been challenged by several metaanalyses, randomized controlled trials that not only proved the safety of HSA but its benefi t especially in patients with sepsis, liver failure, hypoalbuminemia, and burns [ 1 -4 ] . HSA administration favorably infl uences plasma thiol-dependent antioxidant status, as well as levels of protein oxidative damage in patients with sepsis and acute respiratory distress syndrome (ARDS) [ 21 , 22 ] .	./cache/cord-018834-4ligp4ak.txt	./txt/cord-018834-4ligp4ak.txt