id author title date pages extension mime words sentences flesch summary cache txt cord-029991-0sy417j0 Longhini, Federico Chest physiotherapy improves lung aeration in hypersecretive critically ill patients: a pilot randomized physiological study 2020-08-03 .txt text/plain 4621 239 39 BACKGROUND: Besides airway suctioning, patients undergoing invasive mechanical ventilation (iMV) benefit of different combinations of chest physiotherapy techniques, to improve mucus removal. The presence of an endotracheal tube impairs the bronchial mucus velocity transport in anaesthetized dogs [2] ; in critically ill patients undergoing invasive mechanical ventilation (iMV), it seriously impairs cough reflex and mucociliary escalator function [3, 4] , promoting the accumulation of tracheobronchial secretions, leading to sequestration and densification of secretions in the lower airways and increasing the risk of pneumonia [5] and lung atelectasis [6] . The aim of this pilot randomized physiological study is assessing the effects of HFCWO on lung aeration and ventilation distribution, as assessed by EIT, in normosecretive and hypersecretive mechanically ventilated patients. Our study shows that chest physiotherapy by HFCWO may improve lung aeration of hypersecretive mechanically ventilated patients, without affecting gas exchange. ./cache/cord-029991-0sy417j0.txt ./txt/cord-029991-0sy417j0.txt