id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-031129-wqkdug42	Carr, Zyad J.	An Update on Systemic Sclerosis and its Perioperative Management	2020-08-29		.txt	text/plain	4637	232	27	RECENT FINDINGS: Evidence shows that patients with SSc demonstrate an increased risk for perioperative myocardial infarction, high rates of interstitial lung disease, pulmonary arterial hypertension, neurological disease, gastric dysmotility disorders, and challenging airway management, all findings that may result in suboptimal perioperative outcomes. Optimal perioperative management and risk stratification should expand beyond the well-described airway challenges and consider numerous systemic manifestations of systemic sclerosis such as pulmonary arterial hypertension, interstitial lung disease, and cardiac sequelae. Separately, pulmonary hypertension related to ILD or SScrelated cardiac involvement may increase both morbidity and mortality in the perioperative period and may be present in 8-12% of SSC patients [23, 25•] . Microstomia is likely a prominent physical feature of challenging airway management in the patient with SSc supported by a meta-analysis of 15 studies that examined risk factors for intensive care unit-related mortality in a mixed ILD population and found a strong correlation between mortality and the application of invasive mechanical ventilation [69] .	./cache/cord-031129-wqkdug42.txt	./txt/cord-031129-wqkdug42.txt