id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-033574-4y53ryoa	Tashiro, Hiroki	Biomarkers for Overweight in Adult-Onset Asthma	2020-10-02		.txt	text/plain	2693	140	53	On serum cytokine and chemokine analyses, the overweight asthma group included significantly more patients with a lower level of tissue growth factor α (TGF-α) (1.1 pg/mL) and higher levels of hsIL-6 (2.5 pg/mL), RANTES/CCL5 (298.5 pg/mL), and vascular endothelial growth factor A (VEGF-A) (63.7 pg/mL), than the non-overweight asthma group (p=0.02, p<0.01, p=0.02, p=0.01, respectively). CONCLUSION: The present study showed that overweight patients with adult-onset asthma were characterized by a higher rate of annual exacerbations and worse lung function despite treatment with high-dose inhaled corticosteroids and lower blood eosinophil counts than non-overweight patients with asthma. 7 Thus, the present study focused only on adult-onset asthma and showed that blood eosinophil counts were significantly lower in overweight patients with asthma than in non-overweight patients with asthma (Table 1) , and they were negatively correlated with BMI (Figure 1 ), consistent with low type 2 inflammation, as described in previous reports.	./cache/cord-033574-4y53ryoa.txt	./txt/cord-033574-4y53ryoa.txt