id author title date pages extension mime words sentences flesch summary cache txt cord-034690-x8lkngra Ridge, Carole A Dual-Energy CT Pulmonary Angiography (DECTPA) Quantifies Vasculopathy in Severe COVID-19 Pneumonia 2020-10-29 .txt text/plain 3213 178 46 Qualitative and quantitative analysis of perfused blood volume (PBV) maps recorded: i) perfusion defect 'pattern' (wedge-shaped, mottled or amorphous), ii) presence of PT and CT obstruction index (CTOI) and iii) PBV relative to pulmonary artery enhancement (PBV/PAenh); PBV/PAenh was also compared with seven healthy volunteers and correlated with D-Dimer and CTOI. Accordingly, in the present study we aimed to evaluate the relationships between a quantitative measure of perfusion on DECTPA (relative perfused blood volume, PBV/PAenh) (22) , and i) disease duration, ii) right ventricular dysfunction on echocardiography iii) Ddimer levels and (iv) obstruction score (23) in patients with severe COVID-19 pneumonia. This early data demonstrated perfusion defects on perfused blood volume (PBV) maps, when available, as well as the presence of vascular dilatation on conventional CT, hypercoagulability and an increased dead space in 39 patients suggesting that pulmonary angiopathy was accountable for hypoxia observed in patients requiring mechanical ventilation for severe COVID-19 pneumonia. ./cache/cord-034690-x8lkngra.txt ./txt/cord-034690-x8lkngra.txt