id author title date pages extension mime words sentences flesch summary cache txt cord-102276-0a8hup5y Savage, R. S. Development and validation of multivariable machine learning algorithms to predict risk of cancer in symptomatic patients referred urgently from primary care 2020-10-27 .txt text/plain 3792 227 57 title: Development and validation of multivariable machine learning algorithms to predict risk of cancer in symptomatic patients referred urgently from primary care In use-case 1, the algorithms correctly identify 20% of patients who do not have cancer and may not need an urgent 2WW referral. 10 We report the development and validation of a set of machine learning algorithms to provide a calibrated risk probability of cancer (a score between zero and one, higher values indicating greater risk of cancer) for triaging symptomatic patients. Table 6 shows test performance characteristics for use-case 2 (triage), to identify patients at higher risk of cancer who would be considered for priority through the urgent referral pathway. This paper reports the development and validation of a set of statistical machine learning algorithms based on routine laboratory blood measurements that can predict cancer outcomes for symptomatic patients referred urgently from primary care for possible cancer diagnosis. ./cache/cord-102276-0a8hup5y.txt ./txt/cord-102276-0a8hup5y.txt