id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-252159-6t35bxwv	Ferraù, F.	What we have to know about corticosteroids use during Sars-Cov-2 infection	2020-08-28		.txt	text/plain	5201	237	31	PURPOSE: Glucocorticoids (GCs), alone or associated to other drugs, were widely used in the management of patients affected by severe acute respiratory syndrome caused by SARS-CoV-2 infection, during the recent COVID-19 outbreak. RESULTS: GC treatment can cause symptoms of hypercortisolism, especially in patients with individual hypersensibility, or hypoadrenalism after drug withdrawal, due to hypothalamic–pituitary–adrenal (HPA) axis suppression, with consequences in terms of increased morbidity and mortality risk. On the other hand, prolonged steroids treatment can cause symptoms of hypercortisolism, especially in patients with individual hypersensibility, or hypoadrenalism after drug withdrawal, due to hypothalamic-pituitary-adrenal (HPA) axis suppression. This review summarizes the available data on HPA axis impairment in GC-treated Sars-Cov2 patients, focusing on the risk of adrenal insufficiency and on potential drug interactions during concomitant treatments. This review summarizes the available data on HPA axis impairment in GC-treated Sars-Cov2 patients, focusing on the risk of adrenal insufficiency and on potential drug interactions during concomitant treatments.	./cache/cord-252159-6t35bxwv.txt	./txt/cord-252159-6t35bxwv.txt