id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-252890-of29g89s	Villarreal-Fernandez, Eduardo	A plea for avoiding systematic intubation in severely hypoxemic patients with COVID-19-associated respiratory failure	2020-06-12		.txt	text/plain	1019	57	48	A plea for avoiding systematic intubation in severely hypoxemic patients with COVID-19-associated respiratory failure Eduardo Villarreal-Fernandez 1 , Ravi Patel 1 , Reshma Golamari 2 , Muhammad Khalid 2 , Ami DeWaters 2 and Philippe Haouzi 1* Indeed, since a profound hypoxemia appears to be the hallmark of COVID-19-associated pneumonia, the initial consensus [2] was to start invasive mechanical ventilation as soon as possible due to the overwhelming number of patients in respiratory failure presenting at the same time in a hospital and to prevent the risk of hypoxic cardiac arrest; (2) avoidance of high-flow nasal cannula (HFNC) to reduce respiratory droplet aerosolization for healthcare workers [3] in what was seen as "inevitable" intubations. After an initial increase in oxygen requirement through day 6, patients in this group were all able to be discharged at a time when most of the early-intubated patients were still mechanically ventilated (Fig. 1) .	./cache/cord-252890-of29g89s.txt	./txt/cord-252890-of29g89s.txt