id author title date pages extension mime words sentences flesch summary cache txt cord-255807-7goz1agp Hak, E. Conventional Influenza Vaccination Is Not Associated with Complications in Working-Age Patients with Asthma or Chronic Obstructive Pulmonary Disease 2003-04-15 .txt text/plain 4312 194 41 By using a nested case-control design, the authors studied the effectiveness of the influenza vaccine in reducing severe and fatal complications in 4,241 and 5,966 primary care, working-age patients aged 18–64 years who had asthma or chronic obstructive pulmonary disease during the 1998–1999 and 1999–2000 influenza epidemics in the Netherlands. The risk of influenza-related morbidity and mortality during influenza epidemics is high (1) (2) (3) (4) , and nonexperimental studies have shown that vaccination against influenza prevents respiratory and cardiac complications during epidemics in elderly patients with chronic obstructive pulmonary disease (COPD) (5, 6) . We determined the occurrence of respiratory and cardiac morbidity during influenza periods and the clinical effectiveness of vaccination in reducing these complications in patients aged 18-64 years who had asthma or COPD by using a prospective, nested case-control design. ./cache/cord-255807-7goz1agp.txt ./txt/cord-255807-7goz1agp.txt