id author title date pages extension mime words sentences flesch summary cache txt cord-261240-osbk041e Bermejo-Martin, Jesús F Lymphopenic community acquired pneumonia as signature of severe COVID-19 infection 2020-03-05 .txt text/plain 969 55 44 The presence of lymphopenia as a signature of severe COVID-19 was confirmed by Wang D et al., who, in their study published in JAMA, reported that ICU patients suffering this infection had a median lymphocyte count of 800 cells/mm [3] , with non survivors exhibiting persistent lymphopenia [4] . Interestingly, hypercytokinemia and lymphopenia were also evident in critical patients with Severe Acute Respiratory Syndrome due to the Coronavirus emerged in 2003 (SARS-CoV) [5 , 6] . These features (lymphopenia + hypercytokinemia) fit the characteristics of a particular immunological phenotype of community acquired pneumonia (CAP), lymphopenic CAP (L-CAP), which, as we recently demonstrated in an article published in the Journal of Infection, is associated with increased severity, mortality and a dysregulated immunological response [7] . Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China ./cache/cord-261240-osbk041e.txt ./txt/cord-261240-osbk041e.txt