id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-265262-r01u4jr6	Cannarella, Rossella	Systemic effects of the hormonal treatment of male hypogonadism with preliminary indications for the management of COVID-19 patients	2020-10-13		.txt	text/plain	8737	471	47	Furthermore, recent findings on novel coronavirus disease (COVID-19) epidemiology have shown a greater mortality in male compared with female patients and a role of T in promoting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection of the host cells has been demonstrated. To accomplish the aims of the study, we performed a search on PubMed, Scopus, Ovid and Science Direct, and the following keywords were used: hypogonadism, TD, TRT, blood pressure, hypertension, ischemic heart disease, heart failure, stroke, obesity, insulin, diabetes, metabolic disorders, prostatic hyperplasia, prostate cancer, COVID-19, and SARS-CoV2. 45 In 2017, a meta-analysis including 39 randomized controlled trials (RCTs) and 10 observational studies with a total of about 5500 patients did not find any significant association between TRT and myocardial infarction, stroke, or mortality, even if the quality of the evidence was low.	./cache/cord-265262-r01u4jr6.txt	./txt/cord-265262-r01u4jr6.txt