id author title date pages extension mime words sentences flesch summary cache txt cord-269425-e9iyso7n Bhattacharjee, Sukrita Immune Thrombocytopenia Secondary to COVID-19: a Systematic Review 2020-09-19 .txt text/plain 5418 319 46 A systematic review was done to analyze the clinical profile and outcomes in a total of 45 cases of new-onset ITP in COVID-19 patients described in literature until date. Diagnosis of ITP in patients with moderate-to-severe COVID-19 poses a major diagnostic as well as therapeutic challenge to clinicians owing to presence of multiple concomitant conditions including HLH, DIC, sepsis, antibiotic use, heparin prophylaxis, and thromboembolic events. The following data were extracted from the included studies: age of the patient at presentation, gender, COVID-19 illness severity, comorbidities, medication use, nadir platelet count, onset of COVID-19 symptoms to diagnosis of ITP, bleeding manifestations of ITP, time to recovery from start of treatment, and clinical outcomes. Bone marrow study in these few selected cases of ITP would reveal low number of megakaryocytes, as seen in one patient of this review, who presented with severe thrombocytopenia (count 2 × 10 9 /μL) [7] . ./cache/cord-269425-e9iyso7n.txt ./txt/cord-269425-e9iyso7n.txt