id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-270327-v4td3zsa	Atallah, Bassam	A Marker of Systemic Inflammation or Direct Cardiac Injury: Should Cardiac Troponin Levels be Monitored in COVID-19 Patients?	2020-04-29		.txt	text/plain	1691	95	47	The first and perhaps most significant overlap between COVID-19 and cardiac disease lies in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)'s pathogenicity and virulence. Of this cohort, 19.7% of patients had cardiac injury, accompanied by more comorbidities, and higher levels of C-reactive protein (CRP), procalcitonin, creatine kinasemyocardial band (MB fraction), myoglobin, high-sensitivity troponin I (hs-cTnI), N-terminal pro-B-type natriuretic peptide (NT-proBNP), aspartate aminotransferase (AST) and creatinine. 5 With relation to COVID-19, a meta-analyses of four studies that included a total of 341 patients in China found the values of cTnI to be significantly increased in cases of severe disease (SMD, 25.6 ng/L; 95% CI, 6.8-44.5 ng/L) compared to milder forms. Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China. Association of troponin level and age with mortality in 250 000 patients: cohort study across five UK acute care centres.	./cache/cord-270327-v4td3zsa.txt	./txt/cord-270327-v4td3zsa.txt