id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-275154-vwnpred5	Bermejo-Martin, Jesus F	Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza	2009-12-11		.txt	text/plain	4648	260	48	Conclusions While infection with the nvH1N1 induces a typical innate response in both mild and severe patients, severe disease with respiratory involvement is characterized by early secretion of Th17 and Th1 cytokines usually associated with cell mediated immunity but also commonly linked to the pathogenesis of autoimmune/inflammatory diseases. Conclusions While infection with the nvH1N1 induces a typical innate response in both mild and severe patients, severe disease with respiratory involvement is characterized by early secretion of Th17 and Th1 cytokines usually associated with cell mediated immunity but also commonly linked to the pathogenesis of autoimmune/inflammatory diseases. To determine if host immune responses play a potential role in the evolution of mild or severe nvH1N1 illness we performed an analysis of systemic chemokine and cytokine levels in serum from severe and mild nvH1N1 patients shortly following the onset of symptoms.	./cache/cord-275154-vwnpred5.txt	./txt/cord-275154-vwnpred5.txt