id author title date pages extension mime words sentences flesch summary cache txt cord-277148-xzpuc22p Ammirati, Enrico UPDATE ON ACUTE MYOCARDITIS 2020-06-01 .txt text/plain 5852 280 37 Acute myocarditis (AM), a recent-onset inflammation of the heart, has heterogeneous clinical presentations, varying from minor symptoms to high-risk cardiac conditions with severe heart failure, refractory arrhythmias, and cardiogenic shock. In the last decade, the measurement of high-sensitive (hs) troponin levels for identifying myocardial injury and the use of cardiac magnetic resonance imaging (CMRI) for characterizing myocardial tissue changes, allowed to diagnose AM non-invasively and with reasonable accuracy, in a wider population of patients including low-risk subjects. Attention will be paid to contemporary outcomes and predictors of prognosis, the emerging entity of immune checkpoint inhibitors (ICI)-associated myocarditis, updated CMRI diagnostic criteria, new data on the use of temporary mechanical circulatory supports (MCS) in FM. Thus, simple factors such as clinical presentation, wide QRS, and reduced LVEF on admission can help identifying high-risk patients, in whom EMB is recommended to guide subsequent therapeutic strategies (e.g. search for specific etiologies or associated conditions, immunosuppressive regimen, short-term temporary MCS, and screening for HTx listing). ./cache/cord-277148-xzpuc22p.txt ./txt/cord-277148-xzpuc22p.txt