id author title date pages extension mime words sentences flesch summary cache txt cord-281729-z321pebe Santos, Cláudia Pathophysiology of acute fibrinous and organizing pneumonia – Clinical and morphological spectra 2019-05-02 .txt text/plain 3045 150 36 Three clinical cases of patients presenting severe lung disease requiring mechanical ventilation and prolonged intensive care fitted on the variable spectra of AFOP histopathology and had poor outcome: a 23 year-old women had AFOP in the context of antiphospholipid syndrome pulmonary compromise; a 35 year-old man developed a letal intensive care pneumonia with AFOP pattern registered in post-mortem biopsy; and a 79 year-old man died 21 days after intensive care unit treatment of a sub-pleural organizing pneumonia with intra-alveolar fibrin, seen in post-mortem biopsy. Reporting these three clinical cases had the purpose to highlight the acute presentation of AFOP as a particular lung disease more recently described, initially confused with pneumonia, running with severe respiratory failure and immediate need for mechanic ventilation, with no response to antibiotics or steroids. ./cache/cord-281729-z321pebe.txt ./txt/cord-281729-z321pebe.txt