id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-284576-nemh4wdo	Sims, Jonathan T.	Characterization of the Cytokine Storm Reflects Hyperinflammatory Endothelial Dysfunction in COVID-19	2020-09-10		.txt	text/plain	1643	91	42	Methods Blood samples from adult patients hospitalized with COVID-19 were analyzed using high-throughput and ultrasensitive proteomic platforms and compared with ageand sex-matched healthy controls to provide insights into differential regulation of 185 markers. Objective: To identify and characterize the host inflammatory response to SARS-CoV-2 59 infection, we assessed levels of proteins related to immune responses and cardiovascular 60 disease, in patients stratified as mild, moderate, and severe, versus matched healthy controls. Objective: To identify and characterize the host inflammatory response to SARS-CoV-2 59 infection, we assessed levels of proteins related to immune responses and cardiovascular 60 disease, in patients stratified as mild, moderate, and severe, versus matched healthy controls. Furthermore, in a limited series of patients who were sampled 69 frequently confirming reliability and reproducibility of our assays, we demonstrate that 70 intervention with baricitinib attenuates these circulating biomarkers associated with the cytokine 71 The COVID-19 pandemic created an overwhelming need to define host-derived molecular 96 mediators of disease severity evident in hospitalized patients.	./cache/cord-284576-nemh4wdo.txt	./txt/cord-284576-nemh4wdo.txt