id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-287468-e5h4tmy6	Lopez, Alexandre	Effects of Hydroxychloroquine on Covid-19 in Intensive Care Unit Patients: Preliminary Results	2020-08-08		.txt	text/plain	1978	124	52	The primary objective of our study was to assess the effects of hydroxychloroquine according to its plasma concentration in ICU patients. reported that hydroxychloroquine and azithromycin was associated with viral load reduction in nasopharyngeal samples in patients after six days of treatment [6] . The Surviving Sepsis Campaign guidelines on the management of Covid-19 patients concluded there was insufficient evidence to recommend the use of antiviral drugs and hydroxychloroquine in ICU patients [7] . Confirmed Covid-19 patients with acute respiratory failure were included in the study if they completed the criteria: i) age of 18 or older and; ii) polymerase chain reaction (PCR) documented SARS-CoV-2 in nasopharyngeal samples upon ICU admission. In conclusion, our results showed that there was no association between the plasma concentration of hydroxychloroquine and the viral and clinical evolution of ICU patients admitted for Covid-19.	./cache/cord-287468-e5h4tmy6.txt	./txt/cord-287468-e5h4tmy6.txt