id author title date pages extension mime words sentences flesch summary cache txt cord-288181-9thl46oe Fekkar, Arnaud Fungal Infection during COVID-19: Does Aspergillus Mean Secondary Invasive Aspergillosis? 2020-09-15 .txt text/plain 1536 92 38 The authors report a high incidence of presumed invasive pulmonary aspergillosis (6 of 31; 19.4%) among patients with coronavirus disease (COVID-19) admitted to intensive care. The association between aspergillosis and COPD is well known; in a recent prospective study, 14% of patients with COPD exacerbations had respiratory samples with Aspergillus spp. We thank Fekkar and colleagues for their thoughtful comments on our case series of patients with coronavirus disease (COVID-19)-associated pulmonary aspergillosis (CAPA) (1). Cohort studies in patients with influenza-associated pulmonary aspergillosis (IAPA) in the ICU demonstrated that any indication of Aspergillus through positive culture or galactomannan (GM) detection is highly indicative of invasive aspergillosis (2) . Reports of presumed CAPA cases that survive without antifungal therapy, such as those presented by Fekkar and Alanio, are very informative and suggest that in patients with COVID-19, Aspergillus colonization is more common compared with in patients with influenza (5) . ./cache/cord-288181-9thl46oe.txt ./txt/cord-288181-9thl46oe.txt