id author title date pages extension mime words sentences flesch summary cache txt cord-288697-9dywuhkc Noone, Rachel LETTER TO THE EDITOR: NEW ONSET PSYCHOSIS AND MANIA FOLLOWING COVID-19 INFECTION 2020-08-08 .txt text/plain 1312 87 49 Here we present two case reports of adult patients with COVID-19 infections who presented with severe psychosis and mania with no prior psychiatric history and in the absence of significant medical or pulmonary symptoms and an unremarkable neurological work-up. Clinical presentation: Patient-A presented with one week of insomnia and two days of altered behavior including confusion, decreased appetite, and grandiosity and making odd statements. Three weeks prior to his ED admission, Patient-A was diagnosed with presumed COVID-19, treated with oral azithromycin, and told to self-quarantine. J o u r n a l P r e -p r o o f These cases illustrate an association of neuropsychiatric symptoms with COVID-19 infection, in the absence of personal or family history of psychiatric illness, as well as the absence of hypoxemia, cerebral infarction or significant pulmonary involvement. Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic ./cache/cord-288697-9dywuhkc.txt ./txt/cord-288697-9dywuhkc.txt