id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-296113-syi2fwuo	Peng, Mian	Two mechanically ventilated cases of COVID-19 successfully managed with a sequential ventilation weaning protocol: Two case reports	2020-08-06		.txt	text/plain	2618	148	51	BACKGROUND: Patients with critical coronavirus disease 2019 (COVID-19), characterized by respiratory failure requiring mechanical ventilation (MV), are at high risk of mortality. When their condition did not improve after 2 h of NIV, each patient was advanced to MV [tidal volume (Vt), 6 mL/kg ideal body weight (IBW); 8-10 cmH(2)O of positive end-expiratory pressure; respiratory rate, 20 breaths/min; and 40%-80% FiO(2)] with prone positioning for 12 h/day for the first 5 d of MV. CONCLUSION: A MV protocol attentive to intubation/extubation timing, prone positioning early in MV, infection control, and sequential withdrawal of respiratory support, may be an effective regimen for patients with critical COVID-19. In accordance with this recommendation, we summarize our weaning procedure and associated experience with two critical COVID-19 patients, including intubation timing, use of the prone position, infection control, and sedation titration.	./cache/cord-296113-syi2fwuo.txt	./txt/cord-296113-syi2fwuo.txt