id author title date pages extension mime words sentences flesch summary cache txt cord-300811-l4y7df2f Aggarwal, Gaurav Association of Cardiovascular Disease with Coronavirus Disease 2019 (COVID-19) Severity: A Meta-Analysis 2020-04-28 .txt text/plain 2537 147 46 We conducted a meta-analysis of recent studies that reported the association of CVD with worse prognosis and increased mortality in COVID-19 patients. Inclusion criteria were observational case-control or cohort studies on COVID-19 patients with a history of CVD included, which reported outcomes of COVID-19 infection severity, clearly outlined the definition of "severe disease" and with sample size >10. To this end, we carried out a pooled analysis of current studies and evaluate the association between underlying or previous history of CVD conditions and outcomes of infection severity in COVID-19 patients. Pooled analysis of these studies did not find a significant association between previous history of CVD and mortality in severe COVID-19 disease (OR=1.72; 95% CI: 0.97-3.06, I 2 =0%, Cochran's Q=1.56, p=0.46). A total of 3 (n= 566) studies reported data on mortality in all hospitalized patients COVID-19 disease and pre-existing history of CVD. ./cache/cord-300811-l4y7df2f.txt ./txt/cord-300811-l4y7df2f.txt