id author title date pages extension mime words sentences flesch summary cache txt cord-302821-b9ikg0xy GawaƂko, Monika COVID-19 associated atrial fibrillation: Incidence, putative mechanisms and potential clinical implications 2020-09-01 .txt text/plain 3685 209 34 Here, we review the available evidence for prevalence and incidence of AF in patients infected with the severe acute respiratory syndromecoronavirus 2 (SARS-CoV-2) and discuss disease management approaches and potential treatment options for COVID-19 infected AF patients. Here, we review the available evidence for prevalence and incidence of AF in patients infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and discuss disease management approaches and potential treatment options for COVID-19 infected AF patients. The pathophysiology of COVID-19 related AF is not well understood and proposed putative mechanisms include a reduction in angiotensin-converting enzyme 2 (ACE2) receptor availability, CD147-and sialic acid-spike protein interaction, enhanced inflammatory signalling eventually culmination in inflammatory cytokine storm, direct viral endothelial damage, electrolytes and acid-base balance abnormalities in the acute phase of severe illness and increased adrenergic drive.(28) (Fig. 1) . ./cache/cord-302821-b9ikg0xy.txt ./txt/cord-302821-b9ikg0xy.txt