id author title date pages extension mime words sentences flesch summary cache txt cord-303244-5tfrmsm7 Kugasia, Irfanali R. Amiodarone Toxicity Presenting with Acute Onset of Systemic Inflammatory Response Syndrome and Multiorgan Failure Mimicking Sepsis 2020-10-23 .txt text/plain 2394 155 49 Patient: Male, 73-year-old Final Diagnosis: Amiodarone induced SIRS response and organizing pneumonia Symptoms: Abdominal pain • fever • nausea • vomiting Medication: — Clinical Procedure: Bronchoalveolar lavage • bronchoscopy • trans-bronchial biopsy Specialty: Critical Care Medicine OBJECTIVE: Unusual clinical course BACKGROUND: Amiodarone, an anti-arrhythmic medication, has been associated with the development of multiple organ toxicities. CASE REPORT: A 73-year-old man who was being treated with chronic oral amiodarone for atrial fibrillation presented with flu-like symptoms and fever, pulmonary infiltrate, acute kidney injury, and thrombocytopenia. CONCLUSIONS: This case highlights an atypical and rare presentation of a complication of chronic amiodarone use that presented with acute onset of fever, systemic inflammatory response syndrome, and multiorgan failure masquerading as sepsis. Herein, we describe an unusual case of amiodarone toxicity that presented with acute onset of fever, multiorgan failure, and systemic inflammatory response syndrome that masqueraded as sepsis from a low cumulative dose of approximately 75 g. ./cache/cord-303244-5tfrmsm7.txt ./txt/cord-303244-5tfrmsm7.txt