id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-309395-5yan9fcn	Kazory, Amir	SARS-CoV-2 (COVID-19) and intravascular volume management strategies in the critically ill	2020-04-16		.txt	text/plain	3774	201	38	6 Due to lack of data on treatment strategies specific to more severe cases of COVID-19, available evidence on management of the critically ill needs to be extrapolated to the clinical features of this potentially fatal disease. 27 In support of this notion, Murphy et al reported that among patients with acute lung injury secondary to septic shock, those who received both adequate initial fluid resuscitation as well as conservative late fluid management (i.e., negative to even fluid balance on 2 consecutive days during the first week after sepsis) had the best survival rates compared with those who achieved only one of these goals or neither of the two. 41, 42 In the face of positive fluid balance during the de-escalation phase of sepsis management, one might consider earlier application of renal replacement therapy (RRT), especially in those patients with more severe volume overload, progressive metabolic alkalosis with diuretic use, suboptimal diuretic response or diuretic refractoriness, and development of oliguric AKI.	./cache/cord-309395-5yan9fcn.txt	./txt/cord-309395-5yan9fcn.txt