id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-310166-gt6icwul	Yang, Xiang-Hong	Expert recommendations on blood purification treatment protocol for patients with severe COVID-19(): Recommendation and consensus	2020-04-28		.txt	text/plain	3128	154	50	The basic principles of blood purification treatment for patients with severe COVID-19 mainly include the following: (1) removal of metabolic products such as creatinine and urea nitrogen; removal of various inflammatory mediators by convection, absorption, or plasma replacement; and reshaping of the immune homeostasis; (2) regulation of volume and correction of fluid overload to help maintain hemodynamic stability in critically ill patients; (3) correction of electrolyte and acid-base balance disorders to maintain internal environment stability; (4) control of high fever; and (5) combined treatment with extracorporeal membrane oxygenation (ECMO) for extracorporeal multiple organ support. Based on the above principles, the internationally renowned critical care experts Claudio Ronco and Jean Louis Vincent jointly published an expert review titled "Coronavirus epidemic: preparing for extracorporeal organ support in intensive care" in the focus column of The Lancet Respiratory Medicine, 12 emphasizing their position on blood purification treatment for severe COVID-19: CRRT is the most commonly used blood purification method in clinical practice, and for patients with severe COVID-19 with sepsis and ARDS, blood perfusion/plasma absorption treatment can also be selected to eliminate more inflammatory medium.	./cache/cord-310166-gt6icwul.txt	./txt/cord-310166-gt6icwul.txt