id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-312249-k7dp776s	Srinivasan, L.	Split ventilation with pressure regulators for patient-specific tidal volumes	2020-07-06		.txt	text/plain	823	53	48	title: Split ventilation with pressure regulators for patient-specific tidal volumes As a measure of last resort during the COVID-19 pandemic, single mechanical ventilators have been repurposed to support multiple patients. To overcome these limitations, we demonstrate a split-ventilator configuration that enables individualized patient management by incorporating a commonly available pressure regulator used for gas appliances. In passive splitting, patients receive identical pressure-control ventilation through a plastic tubing adaptor 1, 2 . In an attempt to overcome these limitations, we set out to develop a split-ventilator configuration that enables individualized patient management by incorporating gas appliance pressure regulators. To demonstrate feasibility of independent control of patients at two different tidal volumes (TV1, TV2) from a single ventilator, we ventilated two Drager SelfTestLungs (REF MP02400) from a single Drager Apollo anesthesia machine, split using 22mm OD T-pieces and adapters, including HEPA filters and one-way valves to mitigate cross-contamination ( Figure 1B) . These data suggest that gas pressure regulators could enable independent tidal volume control during split ventilation, when used with patient-level respiratory monitoring and associated alarms.	./cache/cord-312249-k7dp776s.txt	./txt/cord-312249-k7dp776s.txt