id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-313353-uwwih8v3	Di Tano, Giuseppe	Late Pulmonary Embolism after COVID-19 Pneumonia despite Adequate Rivaroxaban Treatment	2020-06-18		.txt	text/plain	1335	73	41	Patients with COVID-19 pneumonia who are receiving non-vitamin K antagonists or direct oral anticoagulants for chronic disease are usually switched to heparin treatment during hospitalization. Four weeks after discharge he experienced an episode of an acute pulmonary embolism while on rivaroxaban therapy with adequate drug plasma levels, and in the absence of strong predisposing risk factors. During the acute infection phase, patients chronically managed with antithrombotic agents (non-vitamin K antagonists (VKAs) and direct oral anticoagulants (DOACs)) are usually switched to alternative parenteral antithrombotic medications such as low molecular weight heparin (LMWH) [2, 3] . In conclusion, our case highlights the risk of later thrombotic complications after COVID-19 infection despite appropriate oral anticoagulant therapy and raises some concern about the underlying mechanism. In patients on chronic oral anticoagulant therapy, discharged after hospitalization for acute COVID-19, close monitoring is recommended, and LMWH replacement should be considered only until evidence of complete remission of disease.	./cache/cord-313353-uwwih8v3.txt	./txt/cord-313353-uwwih8v3.txt