id author title date pages extension mime words sentences flesch summary cache txt cord-314106-r3axl3w1 Porembskaya, Olga Pulmonary Artery Thrombosis: A Diagnosis That Strives for Its Independence 2020-07-18 .txt text/plain 7544 406 40 Chronic obstructive pulmonary disease, asthma, sickle cell anemia, emergency and elective surgery, viral pneumonia, and other conditions could be complicated by PA thrombosis development without concomitant deep vein thrombosis (DVT). However, concurrent with the accumulation of clinical data on VTE complications, the idea of embolism from thrombotic masses in the venous system as the only source of emboli in the branches of the PA started to become doubtful, since no initial thrombus was found in a large number of patients [3, 4] . Studies of viral pneumonias caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) indicate that the development of pulmonary thrombosis is frequent and typical for this disease [19, 21, 22] . Thrombin binding to PAR receptors on the PA endothelium causes a number of effects: formation of thrombi, increase of vascular permeability, secretion of pro-inflammatory cytokines, chemoattractants and adhesion molecules, and upregulation of platelet aggregation and procollagen production [45, 47] . ./cache/cord-314106-r3axl3w1.txt ./txt/cord-314106-r3axl3w1.txt