id author title date pages extension mime words sentences flesch summary cache txt cord-317918-pl625ela Ripa, Marco Secondary Infections in Patients Hospitalized with COVID-19: Incidence and Predictive Factors 2020-10-24 .txt text/plain 905 64 46 title: Secondary Infections in Patients Hospitalized with COVID-19: Incidence and Predictive Factors OBJECTIVES: Aim of our study was to describe the incidence and predictive factors of secondary infections in patients with COVID-19. At multivariable analysis, factors associated with secondary infections were low baseline lymphocyte count (<0.7 vs >0.7 per 10(9)/L: subdistribution hazard ratios (sdHRs) 1.93 [95% CI 1.11-3.35]), baseline PaO(2)/FiO(2) (per 100-points lower: sdHRs 1.56 [95% CI 1.21-2.04]), and intensive-care unit (ICU) admission in the first 48 hours (sdHR 2.51 [95% CI 1.04-6.05]). We subsequently performed inverse probability-weighted (IPW) competing risks multivariable analyses to 159 simultaneously account for indication bias associated with the treatment with biologic immunosuppressive 160 drugs and competing death for the estimation of the cumulative incidence of patients with secondary 161 infections, to provide a more accurate estimate of secondary infections burden [15, 16] . The inverses of these propensities were used as weights in multivariable Fine-Gray models assessing the 167 association between demographic and other clinical or laboratory factors and the risk of secondary infections. ./cache/cord-317918-pl625ela.txt ./txt/cord-317918-pl625ela.txt