id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-321543-qdmvn44h	Webb, J. B.	Computational Simulation to Assess Patient Safety of Uncompensated COVID-19 Two-patient Ventilator Sharing Using the Pulse Physiology Engine	2020-05-26		.txt	text/plain	5535	309	39	The simulated patient outcome metrics were satisfactory when the lung compliance difference between two patients was less than 12 cmH2O/mL, and the oxygen saturation index difference was less than 2 mmHg. Interpretation: In resource-limited regions of the world, the COVID-19 pandemic will result in equipment shortages. The simulated patient outcome metrics were satisfactory when the lung compliance difference between two patients was less than 12 cmH2O/mL, and the oxygen saturation index difference was less than 2 mmHg. In resource-limited regions of the world, the COVID-19 pandemic will result in equipment shortages. The new Pulse multi-patient engine simulates multiple patient physiology engines in lockstep to compute the effects of unequal, and potentially dynamic, differences in patient breathing mechanics when connected in parallel branched breathing circuits subject to a single pressuremode ventilator. Validated ARDS and mechanical ventilator models, with the added ability to specify the patient's respiratory compliance, allows for reasonable COVID-19 pathophysiology simulations.	./cache/cord-321543-qdmvn44h.txt	./txt/cord-321543-qdmvn44h.txt