id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-325863-3t73v4ng	Foss, Francine M.	Attenuated Novel SARS Coronavirus 2 Infection in an Allogeneic Hematopoietic Stem Cell Transplant patient on Ruxolitinib	2020-06-25		.txt	text/plain	1989	113	45	title: Attenuated Novel SARS Coronavirus 2 Infection in an Allogeneic Hematopoietic Stem Cell Transplant patient on Ruxolitinib We report a mild and attenuated SARS CoV-2 infection in a patient who is 17 months post stem cell transplantation and maintained on the JAK/STAT inhibitor ruxolitinib, a proposed novel therapy for SARS CoV-2 pneumonia. Due to the signal transduction role that the JAK-STAT pathway plays in mediating Immune-effector cell activation, there has been interest in pursuing inhibitors of this pathway as potential therapeutic agents in mitigating COVID19-associated lung inflammation 9, 10 . We recently diagnosed COVID19 infection in a patient who was on oral ruxolitinib for management of graft-vs-host disease after allogeneic stem cell transplant and report on his presentation and the evolution of his clinical course. Our patient was 17 months post stem cell transplantation and was maintained on the JAK/STAT inhibitor ruxolitinib, a proposed novel therapy for SARS CoV-2 pneumonia, throughout his clinical course with successful attenuation of symptoms.	./cache/cord-325863-3t73v4ng.txt	./txt/cord-325863-3t73v4ng.txt