id author title date pages extension mime words sentences flesch summary cache txt cord-326703-akn92p1r Bartoletti, Michele Development and validation of a prediction model for severe respiratory failure in hospitalized patients with SARS-Cov-2 infection: a multicenter cohort study (PREDI-CO study) 2020-08-08 .txt text/plain 2209 144 54 title: Development and validation of a prediction model for severe respiratory failure in hospitalized patients with SARS-Cov-2 infection: a multicenter cohort study (PREDI-CO study) OBJECTIVES: We aimed to develop and validate a risk score to predict severe respiratory failure (SRF) among patients hospitalized with coronavirus disease-2019 (COVID-19). In the derivation cohort, multivariate analysis showed that age ≥70 years, obesity, fever at 245 hospitalization (body temperature ≥ 38°C), respiratory rate ≥22 breaths per minute, lymphocytes 246 ≤900/mm3, creatinine ≥ 1 mg/dl, C-reactive protein (CRP) ≥10 mg/dl, and LDH ≥350 UI/L were 247 independent risk factors for developing SRF (Table 4) Assignment of points on the basis of β coefficient for these 8 independent variables generated an 255 individual risk score for each patient ranging from 0-9 (Table 4) Table 1) . ./cache/cord-326703-akn92p1r.txt ./txt/cord-326703-akn92p1r.txt