id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-327764-4nlg26p5	Sun, Da-wei	The underlying changes and predicting role of peripheral blood inflammatory cells in severe COVID-19 patients: a sentinel?	2020-05-14		.txt	text/plain	5144	232	48	However, the underlying changes of other peripheral blood inflammatory cells (PBICs) in COVID-19 patients are little known, especially eosinophil level and lymphocyte subsets. When compared with patients in recovery phase, patients in acute phase suffered from significantly decreased counts of lymphocytes (1.383±0.442 On the contrary, 7 patients developed respiratory failure and used mechanical ventilation during the treatment, which were defined as cases with aggravation. Based on these background along with the decrease of multiple PBICs in COVID-19 patients, we hypothesized that neutrophils, eosinophils and lymphocytes migrate from peripheral blood into the lung tissue, resulting in neutropenia, lymphopenia, and eosinopenia in peripheral blood, as well as acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) in COVID-19 patients. In another study based on 44 patients, lymphocyte subsets analyzed results showed that the total number of B cells, T cells and natural killer (NK) cells decreased in the whole group, and this decrease became more evident in the cases of severe type when compared with non-severe type (743.6/uL vs 1020.1/uL; P =0.032) [19] .	./cache/cord-327764-4nlg26p5.txt	./txt/cord-327764-4nlg26p5.txt