id author title date pages extension mime words sentences flesch summary cache txt cord-331519-ye4dtna5 Garibaldi, B. T. Patient trajectories and risk factors for severe outcomes among persons hospitalized for COVID-19 in the Maryland/DC region 2020-05-26 .txt text/plain 4517 295 55 Conclusions: A combination of demographic and clinical features on admission is strongly associated with progression to severe disease or death in a US cohort of COVID-19 patients. In a sub-group analysis of patients < 60 years of age, we identified male sex (aHR 1.7;95%CI 1.11-2.58), BMI (aHR 1.25 per 5-unit increase; 95%CI 1.14-1.37), CCI (aHR 1.27; 95%CI 1.1-1.46) and respiratory rate (aHR 1.16 per increase of 1 over 18; 95%CI 1.13-1.2) as significantly associated with severe illness or death ( Table 2, Table S5 ). Our study provides valuable insight into the disease trajectories of hospitalized COVID-19 patients in the US and the risk factors associated with severe outcomes. In conclusion, we identified several important demographic and simple to assess factors associated with severe COVID-19 outcomes including age, nursing home status, BMI, D-dimer, troponin, ALC and respiratory rate. ./cache/cord-331519-ye4dtna5.txt ./txt/cord-331519-ye4dtna5.txt