id author title date pages extension mime words sentences flesch summary cache txt cord-335338-wzxjn5ip Wei, Lan Pathology of the thyroid in severe acute respiratory syndrome() 2006-09-25 .txt text/plain 3536 169 44 To further investigate the effects of SARS associated coronavirus (CoV) on the thyroid, we have undertaken a detailed study of the thyroid gland with special attention to the pattern of cellular and architectural alterations on parafollicular and follicular cells. In contrast to normal thyroid, the thyroid glands from patients with SARS consistently showed destruction of the follicular epithelium and exfoliation of epithelial cells into the follicle. Our study has demonstrated that thyroid glands in patients with SARS were significantly affected by the disease with extensive injury to the follicular epithelial cells and the parafollicular cells. The extent of morphological injury and the large quantity of cells undergoing apoptosis that we observed in the thyroid follicular epithelium provide an explanation for the diminished serum T3 and T4 levels in patients with SARS. Evaluation and observation of serum thyroid hormone and parathyroid hormone in patients with severe acute respiratory syndrome The 3a protein of severe acute respiratory syndrome-associated coronavirus induces apoptosis in Vero E6 cells ./cache/cord-335338-wzxjn5ip.txt ./txt/cord-335338-wzxjn5ip.txt