id author title date pages extension mime words sentences flesch summary cache txt cord-335593-cjb0daps Romagnolo, Alberto Neurological comorbidity and severity of COVID-19 2020-08-04 .txt text/plain 3430 167 36 However, no data have been reported yet on the prevalence and the association with infection severity of pre-existing neurological comorbidities in COVID-19 patients. In this study, we evaluated the prevalence of neurological pre-existing comorbidities in a large cohort of patients admitted to ER and diagnosed with COVID-19, estimating their association with infection severity. Patients with neurological comorbidity showed an OR of 2.3 of suffering from severe COVID-19, even after including age and other clinical and demographic characteristics in the multivariate analysis. In conclusion, our study reports the prevalence of different neurological diseases in a large cohort of patients with COVID-19, assessing their association with the infection severity. In our sample, patients with pre-existing neurological diseases showed a significantly higher risk for severe infection, in particular when associated with other comorbidities, suggesting that this population deserves a thorough evaluation since the earliest phases of overt or suspected COVID-19. ./cache/cord-335593-cjb0daps.txt ./txt/cord-335593-cjb0daps.txt