id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-335680-wsczl68g	Brown, Charles A.	Myocarditis and idiopathic dilated cardiomyopathy	1995-09-30		.txt	text/plain	3391	196	36	Idiopathic dilated cardiomyopathy (IDC)-namely, left ventricular dilation and systolic dysfunction in the absence of coronary, valvular, or congenital heart diseases-accounts for 25% of these cases.' Progress has only recently been made, however, in our understanding of the relationship between the inciting event or agent and the development of IDC. Radionuclide scanning using gallium-67 or indium-1 11 antimyosin antibody may reveal inflammation or necrosis suggestive of myocarditi, but these tests lack the necessary sensitivity and specificity to be applied as screening tools.ZO Some patients experience a clinical syndrome consistent with myocardial infarction with typical chest pain, ST-T segment changes, wall motion abnormalities, enzyme alterations, and even Q-wave development, but have normal coronary arteries angiographically. Preliminary studies that followed the expanded application of endomyocardial biopsy for detection of cardiac allograft rejection to include patients with unexplained heart failure resulted in a therapeutic dilemma for clinicians. Detection of coxsackle B virus-specific RNA sequences in myocardial biopsy samples from patients with myocarditis and dilated cardiomyopathy	./cache/cord-335680-wsczl68g.txt	./txt/cord-335680-wsczl68g.txt