id author title date pages extension mime words sentences flesch summary cache txt cord-340650-mwsa326c Elangovan, E. J. Rationale and prognosis of repurposed drugs with risk stratification of patients in oxygen support in COVID-19: A systematic review and meta-analysis 2020-10-06 .txt text/plain 6398 349 51 Inclusion criteria for the study were: i) randomized (RCT) or non-randomized clinical trials (nRCT), prospective or retrospective observational studies (cohort study and case series) ii) research articles, preprints and preliminary reports with comparators (Treatment Vs. Control) or combination of treatment modalities or studies without control group iii) study population could be any age, sex and any region in the world, diagnosed with COVID-19 with either laboratory test-confirmed or Chest computer tomography (CT) iv) any one of these outcomes reported: mortality rate, recovery rate, viral clearance period, clinical improvement of patients in oxygen therapy or invasive mechanical ventilation (IMV) after drug treatment. The following features were extracted: author, study type, date of publication, study period, study place, drug name, cohort size, gender, age, severity condition (mild, moderate, severe and critical); treatment combination, time from symptom onset to the treatment, dosage details, exclusion criteria of drug; precondition of patients (PaO2:FiO2, SpO2 levels, respiratory rate), comorbidity, patients requiring respiratory support such as low flow oxygen support, high flow or Non-Invasive mechanical Ventilation (NIV), IMV or extracorporeal membrane oxygenation (ECMO) (during admission and follow-up); clinical improvement length, viral clearance period; mortality rate; recovery rate and adverse effects. ./cache/cord-340650-mwsa326c.txt ./txt/cord-340650-mwsa326c.txt