id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-344853-s2p2csrx	Hendren, Nicholas S.	Description and Proposed Management of the Acute COVID-19 Cardiovascular Syndrome	2020-04-16		.txt	text/plain	6688	357	34	A substantial minority of patients hospitalized develop an acute COVID-19 cardiovascular syndrome, which can manifest with a variety of clinical presentations but often presents as an acute cardiac injury with cardiomyopathy, ventricular arrhythmias, and hemodynamic instability in the absence of obstructive coronary artery disease. S ince the index cases were first reported in Wuhan, China, in December 2019, coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global pandemic infecting >1 million individuals by early April 2020. In this document, we focus on a prominent myocarditis-like syndrome involving acute myocardial injury often associated with reduced left ventricular ejection fraction in the absence of obstructive coronary artery disease. Additional studies, including collection of endomyocardial tissue by biopsy and autopsy studies, are required to delineate the pattern and proportion of ACovCS related to acute myocarditis versus general myocardial injury caused by systemic cytokine dysregulation.	./cache/cord-344853-s2p2csrx.txt	./txt/cord-344853-s2p2csrx.txt