id author title date pages extension mime words sentences flesch summary cache txt cord-352215-dhkvh45t Ramachandran, Preethi Increased serum aminotransferase activity and clinical outcomes in Coronavirus disease 2019 2020-06-30 .txt text/plain 2540 151 45 CONCLUSION: Elevated aminotransferases among hospitalized COVID-19 patients is associated with higher rates of mechanical ventilation, but did not achieve statistical significance after controlling for inflammatory markers. Due to these gaps in current knowledge, we aim to measure the prevalence of clinically significant (twice the ULN) elevation of aminotransferase levels in hospitalized COVID-19 patients. Elevated aminotransferases were associated with an increased rate of mechanical ventilation, but did not achieve statistical significance after controlling for inflammatory markers. However, we found that the rate of mechanical ventilation was significantly higher in patients with elevated aminotransferases, but the statistical significance was lost when adjusted for confounding variables. The results of our study show that clinically significant elevation of aminotransferases (2 X ULN) was noted in 13.7% of hospitalized COVID-19 patients. Clinical characteristics of non-ICU hospitalized patients with coronavirus disease 2019 and liver injury: A retrospective study ./cache/cord-352215-dhkvh45t.txt ./txt/cord-352215-dhkvh45t.txt