id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-352889-fl61z3w3	Downs, John B.	Proposal for Coronavirus Disease 2019 Management	2020-05-12		.txt	text/plain	2706	150	41	Support of declining respiratory physiology in patients with acute respiratory distress syndrome (ARDS) has traditionally consisted of supplemental inspired oxygen, tracheal intubation, augmented tidal volumes from a mechanical ventilator and levels of positive end-expiratory pressure (PEEP) less than 15 cm H 2 O, unless inspired oxygen greater than 70% is required to maintain oxygen saturation greater than 80% (3) (4) (5) . During the severe acute respiratory syndrome (SARS) epidemic in 2003, one report demonstrated a significant decrease in need for tracheal intubation and mechanical ventilation using facemask CPAP. With either technique, the end-expiratory pressure is most effective when titrated to a patient's need and almost always is greater than 10 cm including patients with viral pneumonia with a Pao 2 /Fio 2 ratio less than 200 mm Hg. These reports suggest that early use of higher levels of CPAP may decrease the need for tracheal intubation and mechanical ventilation in patients with ARDS and SARS, with a decrease in attendant complications (VILI and VAP) (19) (20) (21) .	./cache/cord-352889-fl61z3w3.txt	./txt/cord-352889-fl61z3w3.txt