id sid tid token lemma pos cord-010398-5wot7tix 1 1 key key JJ cord-010398-5wot7tix 1 2 : : : cord-010398-5wot7tix 1 3 cord-010398 cord-010398 XX cord-010398-5wot7tix 1 4 - - HYPH cord-010398-5wot7tix 1 5 5wot7tix 5wot7tix VBN cord-010398-5wot7tix 1 6 authors author NNS cord-010398-5wot7tix 1 7 : : : cord-010398-5wot7tix 1 8 Clauw Clauw NNP cord-010398-5wot7tix 1 9 , , , cord-010398-5wot7tix 1 10 Daniel Daniel NNP cord-010398-5wot7tix 1 11 J. J. NNP cord-010398-5wot7tix 1 12 title title NN cord-010398-5wot7tix 1 13 : : : cord-010398-5wot7tix 1 14 Perspectives perspective NNS cord-010398-5wot7tix 1 15 on on IN cord-010398-5wot7tix 1 16 Fatigue Fatigue NNP cord-010398-5wot7tix 1 17 from from IN cord-010398-5wot7tix 1 18 the the DT cord-010398-5wot7tix 1 19 Study Study NNP cord-010398-5wot7tix 1 20 of of IN cord-010398-5wot7tix 1 21 Chronic Chronic NNP cord-010398-5wot7tix 1 22 Fatigue Fatigue NNP cord-010398-5wot7tix 1 23 Syndrome Syndrome NNP cord-010398-5wot7tix 1 24 and and CC cord-010398-5wot7tix 1 25 Related Related NNP cord-010398-5wot7tix 1 26 Conditions Conditions NNPS cord-010398-5wot7tix 1 27 date date NN cord-010398-5wot7tix 1 28 : : : cord-010398-5wot7tix 1 29 2010 2010 CD cord-010398-5wot7tix 1 30 - - SYM cord-010398-5wot7tix 1 31 05 05 CD cord-010398-5wot7tix 1 32 - - HYPH cord-010398-5wot7tix 1 33 31 31 CD cord-010398-5wot7tix 1 34 journal journal NN cord-010398-5wot7tix 1 35 : : : cord-010398-5wot7tix 2 1 PM pm NN cord-010398-5wot7tix 2 2 R r NN cord-010398-5wot7tix 2 3 DOI doi NN cord-010398-5wot7tix 2 4 : : : cord-010398-5wot7tix 3 1 10.1016 10.1016 CD cord-010398-5wot7tix 3 2 / / SYM cord-010398-5wot7tix 3 3 j.pmrj.2010.04.010 j.pmrj.2010.04.010 NN cord-010398-5wot7tix 3 4 sha sha NN cord-010398-5wot7tix 3 5 : : : cord-010398-5wot7tix 3 6 6b7bf82cb2c185080cb15545f5b26a65560c2f65 6b7bf82cb2c185080cb15545f5b26a65560c2f65 CD cord-010398-5wot7tix 3 7 doc_id doc_id CD cord-010398-5wot7tix 3 8 : : : cord-010398-5wot7tix 3 9 10398 10398 CD cord-010398-5wot7tix 3 10 cord_uid cord_uid NNS cord-010398-5wot7tix 3 11 : : : cord-010398-5wot7tix 4 1 5wot7tix 5wot7tix NNP cord-010398-5wot7tix 4 2 Fatigue Fatigue NNP cord-010398-5wot7tix 4 3 is be VBZ cord-010398-5wot7tix 4 4 a a DT cord-010398-5wot7tix 4 5 symptom symptom NN cord-010398-5wot7tix 4 6 whose whose WP$ cord-010398-5wot7tix 4 7 causes cause NNS cord-010398-5wot7tix 4 8 are be VBP cord-010398-5wot7tix 4 9 protean protean JJ cord-010398-5wot7tix 4 10 and and CC cord-010398-5wot7tix 4 11 whose whose WP$ cord-010398-5wot7tix 4 12 phenotype phenotype NN cord-010398-5wot7tix 4 13 includes include VBZ cord-010398-5wot7tix 4 14 physical physical JJ cord-010398-5wot7tix 4 15 , , , cord-010398-5wot7tix 4 16 mood mood NN cord-010398-5wot7tix 4 17 , , , cord-010398-5wot7tix 4 18 and and CC cord-010398-5wot7tix 4 19 behavioral behavioral JJ cord-010398-5wot7tix 4 20 components component NNS cord-010398-5wot7tix 4 21 . . . cord-010398-5wot7tix 5 1 Chronic chronic JJ cord-010398-5wot7tix 5 2 fatigue fatigue NN cord-010398-5wot7tix 5 3 syndrome syndrome NN cord-010398-5wot7tix 5 4 ( ( -LRB- cord-010398-5wot7tix 5 5 CFS CFS NNP cord-010398-5wot7tix 5 6 ) ) -RRB- cord-010398-5wot7tix 5 7 is be VBZ cord-010398-5wot7tix 5 8 an an DT cord-010398-5wot7tix 5 9 illness illness NN cord-010398-5wot7tix 5 10 that that WDT cord-010398-5wot7tix 5 11 has have VBZ cord-010398-5wot7tix 5 12 strong strong JJ cord-010398-5wot7tix 5 13 biological biological JJ cord-010398-5wot7tix 5 14 underpinnings underpinning NNS cord-010398-5wot7tix 5 15 and and CC cord-010398-5wot7tix 5 16 no no DT cord-010398-5wot7tix 5 17 definite definite JJ cord-010398-5wot7tix 5 18 etiology etiology NN cord-010398-5wot7tix 5 19 . . . cord-010398-5wot7tix 6 1 Diagnostic diagnostic JJ cord-010398-5wot7tix 6 2 criteria criterion NNS cord-010398-5wot7tix 6 3 established establish VBN cord-010398-5wot7tix 6 4 by by IN cord-010398-5wot7tix 6 5 the the DT cord-010398-5wot7tix 6 6 Centers Centers NNPS cord-010398-5wot7tix 6 7 for for IN cord-010398-5wot7tix 6 8 Disease Disease NNP cord-010398-5wot7tix 6 9 Control Control NNP cord-010398-5wot7tix 6 10 and and CC cord-010398-5wot7tix 6 11 Prevention Prevention NNP cord-010398-5wot7tix 6 12 have have VBP cord-010398-5wot7tix 6 13 helped help VBN cord-010398-5wot7tix 6 14 classify classify VB cord-010398-5wot7tix 6 15 CFS CFS NNP cord-010398-5wot7tix 6 16 as as IN cord-010398-5wot7tix 6 17 an an DT cord-010398-5wot7tix 6 18 overlap overlap NN cord-010398-5wot7tix 6 19 of of IN cord-010398-5wot7tix 6 20 mood mood NN cord-010398-5wot7tix 6 21 , , , cord-010398-5wot7tix 6 22 behavioral behavioral JJ cord-010398-5wot7tix 6 23 , , , cord-010398-5wot7tix 6 24 and and CC cord-010398-5wot7tix 6 25 biological biological JJ cord-010398-5wot7tix 6 26 components component NNS cord-010398-5wot7tix 6 27 . . . cord-010398-5wot7tix 7 1 These these DT cord-010398-5wot7tix 7 2 include include VBP cord-010398-5wot7tix 7 3 the the DT cord-010398-5wot7tix 7 4 presence presence NN cord-010398-5wot7tix 7 5 of of IN cord-010398-5wot7tix 7 6 fatigue fatigue NN cord-010398-5wot7tix 7 7 for for IN cord-010398-5wot7tix 7 8 more more JJR cord-010398-5wot7tix 7 9 than than IN cord-010398-5wot7tix 7 10 6 6 CD cord-010398-5wot7tix 7 11 months month NNS cord-010398-5wot7tix 7 12 associated associate VBN cord-010398-5wot7tix 7 13 with with IN cord-010398-5wot7tix 7 14 a a DT cord-010398-5wot7tix 7 15 diminution diminution NN cord-010398-5wot7tix 7 16 of of IN cord-010398-5wot7tix 7 17 functional functional JJ cord-010398-5wot7tix 7 18 activity activity NN cord-010398-5wot7tix 7 19 and and CC cord-010398-5wot7tix 7 20 somatic somatic JJ cord-010398-5wot7tix 7 21 symptoms symptom NNS cord-010398-5wot7tix 7 22 , , , cord-010398-5wot7tix 7 23 and and CC cord-010398-5wot7tix 7 24 pain pain NN cord-010398-5wot7tix 7 25 not not RB cord-010398-5wot7tix 7 26 attributable attributable JJ cord-010398-5wot7tix 7 27 to to IN cord-010398-5wot7tix 7 28 a a DT cord-010398-5wot7tix 7 29 specific specific JJ cord-010398-5wot7tix 7 30 diagnosis diagnosis NN cord-010398-5wot7tix 7 31 or or CC cord-010398-5wot7tix 7 32 disease disease NN cord-010398-5wot7tix 7 33 . . . cord-010398-5wot7tix 8 1 Four four CD cord-010398-5wot7tix 8 2 of of IN cord-010398-5wot7tix 8 3 the the DT cord-010398-5wot7tix 8 4 following follow VBG cord-010398-5wot7tix 8 5 criteria criterion NNS cord-010398-5wot7tix 8 6 need need VBP cord-010398-5wot7tix 8 7 to to TO cord-010398-5wot7tix 8 8 be be VB cord-010398-5wot7tix 8 9 present present JJ cord-010398-5wot7tix 8 10 : : : cord-010398-5wot7tix 8 11 sore sore JJ cord-010398-5wot7tix 8 12 throat throat NN cord-010398-5wot7tix 8 13 , , , cord-010398-5wot7tix 8 14 impaired impaired JJ cord-010398-5wot7tix 8 15 memory memory NN cord-010398-5wot7tix 8 16 or or CC cord-010398-5wot7tix 8 17 cognition cognition NN cord-010398-5wot7tix 8 18 , , , cord-010398-5wot7tix 8 19 unrefreshing unrefreshing NN cord-010398-5wot7tix 8 20 sleep sleep NN cord-010398-5wot7tix 8 21 , , , cord-010398-5wot7tix 8 22 postexertional postexertional JJ cord-010398-5wot7tix 8 23 fatigue fatigue NN cord-010398-5wot7tix 8 24 , , , cord-010398-5wot7tix 8 25 tender tender NN cord-010398-5wot7tix 8 26 glands gland NNS cord-010398-5wot7tix 8 27 , , , cord-010398-5wot7tix 8 28 aching ache VBG cord-010398-5wot7tix 8 29 stiff stiff JJ cord-010398-5wot7tix 8 30 muscles muscle NNS cord-010398-5wot7tix 8 31 , , , cord-010398-5wot7tix 8 32 joint joint JJ cord-010398-5wot7tix 8 33 pain pain NN cord-010398-5wot7tix 8 34 , , , cord-010398-5wot7tix 8 35 and and CC cord-010398-5wot7tix 8 36 headaches headache NNS cord-010398-5wot7tix 8 37 . . . cord-010398-5wot7tix 9 1 Many many JJ cord-010398-5wot7tix 9 2 researchers researcher NNS cord-010398-5wot7tix 9 3 have have VBP cord-010398-5wot7tix 9 4 observed observe VBN cord-010398-5wot7tix 9 5 that that IN cord-010398-5wot7tix 9 6 CFS CFS NNP cord-010398-5wot7tix 9 7 shares share NNS cord-010398-5wot7tix 9 8 features feature VBZ cord-010398-5wot7tix 9 9 in in IN cord-010398-5wot7tix 9 10 common common JJ cord-010398-5wot7tix 9 11 with with IN cord-010398-5wot7tix 9 12 other other JJ cord-010398-5wot7tix 9 13 somatic somatic JJ cord-010398-5wot7tix 9 14 syndromes syndrome NNS cord-010398-5wot7tix 9 15 , , , cord-010398-5wot7tix 9 16 including include VBG cord-010398-5wot7tix 9 17 irritable irritable JJ cord-010398-5wot7tix 9 18 bowel bowel NN cord-010398-5wot7tix 9 19 syndrome syndrome NN cord-010398-5wot7tix 9 20 , , , cord-010398-5wot7tix 9 21 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 9 22 , , , cord-010398-5wot7tix 9 23 and and CC cord-010398-5wot7tix 9 24 temporomandibular temporomandibular NN cord-010398-5wot7tix 9 25 joint joint JJ cord-010398-5wot7tix 9 26 dysfunction dysfunction NN cord-010398-5wot7tix 9 27 . . . cord-010398-5wot7tix 10 1 Correlations correlation NNS cord-010398-5wot7tix 10 2 between between IN cord-010398-5wot7tix 10 3 inflammation inflammation NN cord-010398-5wot7tix 10 4 and and CC cord-010398-5wot7tix 10 5 infection infection NN cord-010398-5wot7tix 10 6 , , , cord-010398-5wot7tix 10 7 augmented augment VBN cord-010398-5wot7tix 10 8 sensory sensory JJ cord-010398-5wot7tix 10 9 processing processing NN cord-010398-5wot7tix 10 10 , , , cord-010398-5wot7tix 10 11 abnormalities abnormality NNS cord-010398-5wot7tix 10 12 of of IN cord-010398-5wot7tix 10 13 neurotransmitters neurotransmitter NNS cord-010398-5wot7tix 10 14 , , , cord-010398-5wot7tix 10 15 nerve nerve NN cord-010398-5wot7tix 10 16 growth growth NN cord-010398-5wot7tix 10 17 factors factor NNS cord-010398-5wot7tix 10 18 , , , cord-010398-5wot7tix 10 19 low low JJ cord-010398-5wot7tix 10 20 levels level NNS cord-010398-5wot7tix 10 21 of of IN cord-010398-5wot7tix 10 22 serotonin serotonin NN cord-010398-5wot7tix 10 23 and and CC cord-010398-5wot7tix 10 24 norepinephrine norepinephrine NN cord-010398-5wot7tix 10 25 , , , cord-010398-5wot7tix 10 26 abnormalities abnormality NNS cord-010398-5wot7tix 10 27 of of IN cord-010398-5wot7tix 10 28 homeostasis homeostasis NN cord-010398-5wot7tix 10 29 of of IN cord-010398-5wot7tix 10 30 the the DT cord-010398-5wot7tix 10 31 stress stress NN cord-010398-5wot7tix 10 32 system system NN cord-010398-5wot7tix 10 33 , , , cord-010398-5wot7tix 10 34 and and CC cord-010398-5wot7tix 10 35 autonomic autonomic JJ cord-010398-5wot7tix 10 36 dysfunction dysfunction NN cord-010398-5wot7tix 10 37 may may MD cord-010398-5wot7tix 10 38 be be VB cord-010398-5wot7tix 10 39 hallmarks hallmark VBN cord-010398-5wot7tix 10 40 of of IN cord-010398-5wot7tix 10 41 CFS CFS NNP cord-010398-5wot7tix 10 42 . . . cord-010398-5wot7tix 11 1 The the DT cord-010398-5wot7tix 11 2 relative relative JJ cord-010398-5wot7tix 11 3 contributions contribution NNS cord-010398-5wot7tix 11 4 of of IN cord-010398-5wot7tix 11 5 each each DT cord-010398-5wot7tix 11 6 of of IN cord-010398-5wot7tix 11 7 these these DT cord-010398-5wot7tix 11 8 abnormalities abnormality NNS cord-010398-5wot7tix 11 9 to to IN cord-010398-5wot7tix 11 10 the the DT cord-010398-5wot7tix 11 11 profound profound JJ cord-010398-5wot7tix 11 12 fatigue fatigue NN cord-010398-5wot7tix 11 13 associated associate VBN cord-010398-5wot7tix 11 14 with with IN cord-010398-5wot7tix 11 15 CFS CFS NNP cord-010398-5wot7tix 11 16 need need NN cord-010398-5wot7tix 11 17 to to TO cord-010398-5wot7tix 11 18 be be VB cord-010398-5wot7tix 11 19 explored explore VBN cord-010398-5wot7tix 11 20 further further RB cord-010398-5wot7tix 11 21 to to TO cord-010398-5wot7tix 11 22 better better RB cord-010398-5wot7tix 11 23 evaluate evaluate VB cord-010398-5wot7tix 11 24 and and CC cord-010398-5wot7tix 11 25 treat treat VB cord-010398-5wot7tix 11 26 the the DT cord-010398-5wot7tix 11 27 syndrome syndrome NN cord-010398-5wot7tix 11 28 . . . cord-010398-5wot7tix 12 1 Individuals individual NNS cord-010398-5wot7tix 12 2 have have VBP cord-010398-5wot7tix 12 3 been be VBN cord-010398-5wot7tix 12 4 documented document VBN cord-010398-5wot7tix 12 5 as as IN cord-010398-5wot7tix 12 6 experiencing experience VBG cord-010398-5wot7tix 12 7 fatigue fatigue NN cord-010398-5wot7tix 12 8 , , , cord-010398-5wot7tix 12 9 or or CC cord-010398-5wot7tix 12 10 exhaustion exhaustion NN cord-010398-5wot7tix 12 11 in in IN cord-010398-5wot7tix 12 12 certain certain JJ cord-010398-5wot7tix 12 13 circumstances circumstance NNS cord-010398-5wot7tix 12 14 , , , cord-010398-5wot7tix 12 15 since since IN cord-010398-5wot7tix 12 16 written write VBN cord-010398-5wot7tix 12 17 records record NNS cord-010398-5wot7tix 12 18 have have VBP cord-010398-5wot7tix 12 19 been be VBN cord-010398-5wot7tix 12 20 kept keep VBN cord-010398-5wot7tix 12 21 . . . cord-010398-5wot7tix 13 1 The the DT cord-010398-5wot7tix 13 2 earliest early JJS cord-010398-5wot7tix 13 3 medical medical JJ cord-010398-5wot7tix 13 4 literature literature NN cord-010398-5wot7tix 13 5 identifies identify VBZ cord-010398-5wot7tix 13 6 individuals individual NNS cord-010398-5wot7tix 13 7 who who WP cord-010398-5wot7tix 13 8 are be VBP cord-010398-5wot7tix 13 9 chronically chronically RB cord-010398-5wot7tix 13 10 fatigued fatigued JJ cord-010398-5wot7tix 13 11 but but CC cord-010398-5wot7tix 13 12 have have VBP cord-010398-5wot7tix 13 13 no no DT cord-010398-5wot7tix 13 14 other other JJ cord-010398-5wot7tix 13 15 identifiable identifiable JJ cord-010398-5wot7tix 13 16 medical medical JJ cord-010398-5wot7tix 13 17 or or CC cord-010398-5wot7tix 13 18 psychiatric psychiatric JJ cord-010398-5wot7tix 13 19 illness illness NN cord-010398-5wot7tix 13 20 that that WDT cord-010398-5wot7tix 13 21 would would MD cord-010398-5wot7tix 13 22 account account VB cord-010398-5wot7tix 13 23 for for IN cord-010398-5wot7tix 13 24 these these DT cord-010398-5wot7tix 13 25 symptoms symptom NNS cord-010398-5wot7tix 13 26 , , , cord-010398-5wot7tix 13 27 and and CC cord-010398-5wot7tix 13 28 these these DT cord-010398-5wot7tix 13 29 individuals individual NNS cord-010398-5wot7tix 13 30 have have VBP cord-010398-5wot7tix 13 31 been be VBN cord-010398-5wot7tix 13 32 described describe VBN cord-010398-5wot7tix 13 33 by by IN cord-010398-5wot7tix 13 34 many many JJ cord-010398-5wot7tix 13 35 different different JJ cord-010398-5wot7tix 13 36 labels label NNS cord-010398-5wot7tix 13 37 over over IN cord-010398-5wot7tix 13 38 the the DT cord-010398-5wot7tix 13 39 millennia millennium NNS cord-010398-5wot7tix 13 40 . . . cord-010398-5wot7tix 14 1 In in IN cord-010398-5wot7tix 14 2 1869 1869 CD cord-010398-5wot7tix 14 3 , , , cord-010398-5wot7tix 14 4 Beard Beard NNP cord-010398-5wot7tix 14 5 first first RB cord-010398-5wot7tix 14 6 coined coin VBD cord-010398-5wot7tix 14 7 the the DT cord-010398-5wot7tix 14 8 term term NN cord-010398-5wot7tix 14 9 neurasthenia neurasthenia NN cord-010398-5wot7tix 14 10 to to TO cord-010398-5wot7tix 14 11 describe describe VB cord-010398-5wot7tix 14 12 a a DT cord-010398-5wot7tix 14 13 condition condition NN cord-010398-5wot7tix 14 14 that that WDT cord-010398-5wot7tix 14 15 occurred occur VBD cord-010398-5wot7tix 14 16 from from IN cord-010398-5wot7tix 14 17 depletion depletion NN cord-010398-5wot7tix 14 18 of of IN cord-010398-5wot7tix 14 19 the the DT cord-010398-5wot7tix 14 20 central central JJ cord-010398-5wot7tix 14 21 nervous nervous JJ cord-010398-5wot7tix 14 22 system system NN cord-010398-5wot7tix 14 23 's 's POS cord-010398-5wot7tix 14 24 energy energy NN cord-010398-5wot7tix 14 25 reserves reserve NNS cord-010398-5wot7tix 14 26 , , , cord-010398-5wot7tix 14 27 which which WDT cord-010398-5wot7tix 14 28 Beard Beard NNP cord-010398-5wot7tix 14 29 attributed attribute VBD cord-010398-5wot7tix 14 30 to to IN cord-010398-5wot7tix 14 31 the the DT cord-010398-5wot7tix 14 32 consequences consequence NNS cord-010398-5wot7tix 14 33 of of IN cord-010398-5wot7tix 14 34 aspects aspect NNS cord-010398-5wot7tix 14 35 of of IN cord-010398-5wot7tix 14 36 modern modern JJ cord-010398-5wot7tix 14 37 civilization civilization NN cord-010398-5wot7tix 14 38 . . . cord-010398-5wot7tix 15 1 Physicians physician NNS cord-010398-5wot7tix 15 2 in in IN cord-010398-5wot7tix 15 3 the the DT cord-010398-5wot7tix 15 4 Beard Beard NNP cord-010398-5wot7tix 15 5 school school NN cord-010398-5wot7tix 15 6 of of IN cord-010398-5wot7tix 15 7 thought thought NN cord-010398-5wot7tix 15 8 associated associate VBD cord-010398-5wot7tix 15 9 neurasthenia neurasthenia NN cord-010398-5wot7tix 15 10 with with IN cord-010398-5wot7tix 15 11 the the DT cord-010398-5wot7tix 15 12 stresses stress NNS cord-010398-5wot7tix 15 13 of of IN cord-010398-5wot7tix 15 14 urbanization urbanization NN cord-010398-5wot7tix 15 15 and and CC cord-010398-5wot7tix 15 16 the the DT cord-010398-5wot7tix 15 17 stress stress NN cord-010398-5wot7tix 15 18 experienced experience VBD cord-010398-5wot7tix 15 19 a a DT cord-010398-5wot7tix 15 20 result result NN cord-010398-5wot7tix 15 21 of of IN cord-010398-5wot7tix 15 22 an an DT cord-010398-5wot7tix 15 23 increasingly increasingly RB cord-010398-5wot7tix 15 24 competitive competitive JJ cord-010398-5wot7tix 15 25 business business NN cord-010398-5wot7tix 15 26 environment environment NN cord-010398-5wot7tix 15 27 . . . cord-010398-5wot7tix 16 1 Typically typically RB cord-010398-5wot7tix 16 2 , , , cord-010398-5wot7tix 16 3 the the DT cord-010398-5wot7tix 16 4 condition condition NN cord-010398-5wot7tix 16 5 was be VBD cord-010398-5wot7tix 16 6 associated associate VBN cord-010398-5wot7tix 16 7 with with IN cord-010398-5wot7tix 16 8 members member NNS cord-010398-5wot7tix 16 9 of of IN cord-010398-5wot7tix 16 10 the the DT cord-010398-5wot7tix 16 11 upper upper JJ cord-010398-5wot7tix 16 12 class class NN cord-010398-5wot7tix 16 13 or or CC cord-010398-5wot7tix 16 14 professionals professional NNS cord-010398-5wot7tix 16 15 with with IN cord-010398-5wot7tix 16 16 sedentary sedentary JJ cord-010398-5wot7tix 16 17 employment employment NN cord-010398-5wot7tix 16 18 . . . cord-010398-5wot7tix 17 1 The the DT cord-010398-5wot7tix 17 2 term term NN cord-010398-5wot7tix 17 3 neurasthenia neurasthenia NN cord-010398-5wot7tix 17 4 has have VBZ cord-010398-5wot7tix 17 5 largely largely RB cord-010398-5wot7tix 17 6 been be VBN cord-010398-5wot7tix 17 7 abandoned abandon VBN cord-010398-5wot7tix 17 8 , , , cord-010398-5wot7tix 17 9 and and CC cord-010398-5wot7tix 17 10 no no DT cord-010398-5wot7tix 17 11 evidence evidence NN cord-010398-5wot7tix 17 12 suggests suggest VBZ cord-010398-5wot7tix 17 13 that that IN cord-010398-5wot7tix 17 14 this this DT cord-010398-5wot7tix 17 15 disorder disorder NN cord-010398-5wot7tix 17 16 was be VBD cord-010398-5wot7tix 17 17 one one CD cord-010398-5wot7tix 17 18 of of IN cord-010398-5wot7tix 17 19 urbanization urbanization NN cord-010398-5wot7tix 17 20 . . . cord-010398-5wot7tix 18 1 Many many JJ cord-010398-5wot7tix 18 2 other other JJ cord-010398-5wot7tix 18 3 terms term NNS cord-010398-5wot7tix 18 4 for for IN cord-010398-5wot7tix 18 5 chronic chronic JJ cord-010398-5wot7tix 18 6 fatiguing fatiguing JJ cord-010398-5wot7tix 18 7 illnesses illness NNS cord-010398-5wot7tix 18 8 have have VBP cord-010398-5wot7tix 18 9 arisen arise VBN cord-010398-5wot7tix 18 10 , , , cord-010398-5wot7tix 18 11 inappropriately inappropriately RB cord-010398-5wot7tix 18 12 , , , cord-010398-5wot7tix 18 13 from from IN cord-010398-5wot7tix 18 14 attributing attribute VBG cord-010398-5wot7tix 18 15 the the DT cord-010398-5wot7tix 18 16 chronic chronic JJ cord-010398-5wot7tix 18 17 symptoms symptom NNS cord-010398-5wot7tix 18 18 experienced experience VBN cord-010398-5wot7tix 18 19 by by IN cord-010398-5wot7tix 18 20 patients patient NNS cord-010398-5wot7tix 18 21 with with IN cord-010398-5wot7tix 18 22 these these DT cord-010398-5wot7tix 18 23 illnesses illness NNS cord-010398-5wot7tix 18 24 to to IN cord-010398-5wot7tix 18 25 those those DT cord-010398-5wot7tix 18 26 of of IN cord-010398-5wot7tix 18 27 an an DT cord-010398-5wot7tix 18 28 active active JJ cord-010398-5wot7tix 18 29 infection infection NN cord-010398-5wot7tix 18 30 . . . cord-010398-5wot7tix 19 1 For for IN cord-010398-5wot7tix 19 2 example example NN cord-010398-5wot7tix 19 3 , , , cord-010398-5wot7tix 19 4 terms term NNS cord-010398-5wot7tix 19 5 such such JJ cord-010398-5wot7tix 19 6 as as IN cord-010398-5wot7tix 19 7 Akureyri Akureyri NNP cord-010398-5wot7tix 19 8 disease disease NN cord-010398-5wot7tix 19 9 , , , cord-010398-5wot7tix 19 10 Iceland Iceland NNP cord-010398-5wot7tix 19 11 disease disease NN cord-010398-5wot7tix 19 12 , , , cord-010398-5wot7tix 19 13 Royal Royal NNP cord-010398-5wot7tix 19 14 Free Free NNP cord-010398-5wot7tix 19 15 disease disease NN cord-010398-5wot7tix 19 16 , , , cord-010398-5wot7tix 19 17 and and CC cord-010398-5wot7tix 19 18 Tapanui Tapanui NNP cord-010398-5wot7tix 19 19 flu flu NN cord-010398-5wot7tix 19 20 all all DT cord-010398-5wot7tix 19 21 have have VBP cord-010398-5wot7tix 19 22 been be VBN cord-010398-5wot7tix 19 23 used use VBN cord-010398-5wot7tix 19 24 first first RB cord-010398-5wot7tix 19 25 to to TO cord-010398-5wot7tix 19 26 describe describe VB cord-010398-5wot7tix 19 27 specific specific JJ cord-010398-5wot7tix 19 28 outbreaks outbreak NNS cord-010398-5wot7tix 19 29 of of IN cord-010398-5wot7tix 19 30 patients patient NNS cord-010398-5wot7tix 19 31 with with IN cord-010398-5wot7tix 19 32 chronic chronic JJ cord-010398-5wot7tix 19 33 fatiguing fatiguing JJ cord-010398-5wot7tix 19 34 illnesses illness NNS cord-010398-5wot7tix 19 35 and and CC cord-010398-5wot7tix 19 36 then then RB cord-010398-5wot7tix 19 37 used use VBD cord-010398-5wot7tix 19 38 more more RBR cord-010398-5wot7tix 19 39 widely widely RB cord-010398-5wot7tix 19 40 to to TO cord-010398-5wot7tix 19 41 describe describe VB cord-010398-5wot7tix 19 42 others other NNS cord-010398-5wot7tix 19 43 who who WP cord-010398-5wot7tix 19 44 had have VBD cord-010398-5wot7tix 19 45 demonstrated demonstrate VBN cord-010398-5wot7tix 19 46 similar similar JJ cord-010398-5wot7tix 19 47 symptoms symptom NNS cord-010398-5wot7tix 19 48 . . . cord-010398-5wot7tix 20 1 These these DT cord-010398-5wot7tix 20 2 patients patient NNS cord-010398-5wot7tix 20 3 , , , cord-010398-5wot7tix 20 4 typically typically RB cord-010398-5wot7tix 20 5 affected affect VBN cord-010398-5wot7tix 20 6 by by IN cord-010398-5wot7tix 20 7 severe severe JJ cord-010398-5wot7tix 20 8 postinfectious postinfectious NNP cord-010398-5wot7tix 20 9 fatigue fatigue NN cord-010398-5wot7tix 20 10 , , , cord-010398-5wot7tix 20 11 may may MD cord-010398-5wot7tix 20 12 also also RB cord-010398-5wot7tix 20 13 experience experience VB cord-010398-5wot7tix 20 14 multifocal multifocal JJ cord-010398-5wot7tix 20 15 pain pain NN cord-010398-5wot7tix 20 16 ( ( -LRB- cord-010398-5wot7tix 20 17 including include VBG cord-010398-5wot7tix 20 18 in in IN cord-010398-5wot7tix 20 19 regions region NNS cord-010398-5wot7tix 20 20 such such JJ cord-010398-5wot7tix 20 21 as as IN cord-010398-5wot7tix 20 22 the the DT cord-010398-5wot7tix 20 23 muscles muscle NNS cord-010398-5wot7tix 20 24 , , , cord-010398-5wot7tix 20 25 throat throat NN cord-010398-5wot7tix 20 26 , , , cord-010398-5wot7tix 20 27 and and CC cord-010398-5wot7tix 20 28 neck neck NN cord-010398-5wot7tix 20 29 , , , cord-010398-5wot7tix 20 30 which which WDT cord-010398-5wot7tix 20 31 are be VBP cord-010398-5wot7tix 20 32 painful painful JJ cord-010398-5wot7tix 20 33 during during IN cord-010398-5wot7tix 20 34 many many JJ cord-010398-5wot7tix 20 35 acute acute JJ cord-010398-5wot7tix 20 36 infections infection NNS cord-010398-5wot7tix 20 37 ) ) -RRB- cord-010398-5wot7tix 20 38 , , , cord-010398-5wot7tix 20 39 sleep sleep NN cord-010398-5wot7tix 20 40 disturbances disturbance NNS cord-010398-5wot7tix 20 41 , , , cord-010398-5wot7tix 20 42 memory memory NN cord-010398-5wot7tix 20 43 difficulties difficulty NNS cord-010398-5wot7tix 20 44 , , , cord-010398-5wot7tix 20 45 and and CC cord-010398-5wot7tix 20 46 many many JJ cord-010398-5wot7tix 20 47 other other JJ cord-010398-5wot7tix 20 48 somatic somatic JJ cord-010398-5wot7tix 20 49 symptoms symptom NNS cord-010398-5wot7tix 20 50 . . . cord-010398-5wot7tix 21 1 In in IN cord-010398-5wot7tix 21 2 fact fact NN cord-010398-5wot7tix 21 3 , , , cord-010398-5wot7tix 21 4 in in IN cord-010398-5wot7tix 21 5 the the DT cord-010398-5wot7tix 21 6 United United NNP cord-010398-5wot7tix 21 7 States States NNP cord-010398-5wot7tix 21 8 , , , cord-010398-5wot7tix 21 9 the the DT cord-010398-5wot7tix 21 10 disorder disorder NN cord-010398-5wot7tix 21 11 we -PRON- PRP cord-010398-5wot7tix 21 12 now now RB cord-010398-5wot7tix 21 13 commonly commonly RB cord-010398-5wot7tix 21 14 refer refer VBP cord-010398-5wot7tix 21 15 to to IN cord-010398-5wot7tix 21 16 as as IN cord-010398-5wot7tix 21 17 chronic chronic JJ cord-010398-5wot7tix 21 18 fatigue fatigue NN cord-010398-5wot7tix 21 19 syndrome syndrome NN cord-010398-5wot7tix 21 20 ( ( -LRB- cord-010398-5wot7tix 21 21 CFS CFS NNP cord-010398-5wot7tix 21 22 ) ) -RRB- cord-010398-5wot7tix 21 23 largely largely RB cord-010398-5wot7tix 21 24 came come VBD cord-010398-5wot7tix 21 25 about about RP cord-010398-5wot7tix 21 26 after after IN cord-010398-5wot7tix 21 27 a a DT cord-010398-5wot7tix 21 28 potential potential JJ cord-010398-5wot7tix 21 29 epidemic epidemic NN cord-010398-5wot7tix 21 30 of of IN cord-010398-5wot7tix 21 31 CFS CFS NNP cord-010398-5wot7tix 21 32 that that WDT cord-010398-5wot7tix 21 33 occurred occur VBD cord-010398-5wot7tix 21 34 in in IN cord-010398-5wot7tix 21 35 the the DT cord-010398-5wot7tix 21 36 practice practice NN cord-010398-5wot7tix 21 37 of of IN cord-010398-5wot7tix 21 38 a a DT cord-010398-5wot7tix 21 39 single single JJ cord-010398-5wot7tix 21 40 internist internist NN cord-010398-5wot7tix 21 41 , , , cord-010398-5wot7tix 21 42 Daniel Daniel NNP cord-010398-5wot7tix 21 43 Peterson Peterson NNP cord-010398-5wot7tix 21 44 , , , cord-010398-5wot7tix 21 45 in in IN cord-010398-5wot7tix 21 46 Incline Incline NNP cord-010398-5wot7tix 21 47 Village Village NNP cord-010398-5wot7tix 21 48 , , , cord-010398-5wot7tix 21 49 Nevada Nevada NNP cord-010398-5wot7tix 21 50 , , , cord-010398-5wot7tix 21 51 in in IN cord-010398-5wot7tix 21 52 1984 1984 CD cord-010398-5wot7tix 21 53 [ [ -LRB- cord-010398-5wot7tix 21 54 1 1 CD cord-010398-5wot7tix 21 55 ] ] -RRB- cord-010398-5wot7tix 21 56 . . . cord-010398-5wot7tix 22 1 The the DT cord-010398-5wot7tix 22 2 patients patient NNS cord-010398-5wot7tix 22 3 in in IN cord-010398-5wot7tix 22 4 this this DT cord-010398-5wot7tix 22 5 study study NN cord-010398-5wot7tix 22 6 were be VBD cord-010398-5wot7tix 22 7 extensively extensively RB cord-010398-5wot7tix 22 8 evaluated evaluate VBN cord-010398-5wot7tix 22 9 by by IN cord-010398-5wot7tix 22 10 both both CC cord-010398-5wot7tix 22 11 the the DT cord-010398-5wot7tix 22 12 Centers Centers NNPS cord-010398-5wot7tix 22 13 for for IN cord-010398-5wot7tix 22 14 Disease Disease NNP cord-010398-5wot7tix 22 15 Control Control NNP cord-010398-5wot7tix 22 16 and and CC cord-010398-5wot7tix 22 17 Prevention Prevention NNP cord-010398-5wot7tix 22 18 ( ( -LRB- cord-010398-5wot7tix 22 19 CDC CDC NNP cord-010398-5wot7tix 22 20 ) ) -RRB- cord-010398-5wot7tix 22 21 and and CC cord-010398-5wot7tix 22 22 several several JJ cord-010398-5wot7tix 22 23 academic academic JJ cord-010398-5wot7tix 22 24 groups group NNS cord-010398-5wot7tix 22 25 , , , cord-010398-5wot7tix 22 26 and and CC cord-010398-5wot7tix 22 27 they -PRON- PRP cord-010398-5wot7tix 22 28 were be VBD cord-010398-5wot7tix 22 29 found find VBN cord-010398-5wot7tix 22 30 to to TO cord-010398-5wot7tix 22 31 have have VB cord-010398-5wot7tix 22 32 immunological immunological JJ cord-010398-5wot7tix 22 33 abnormalities abnormality NNS cord-010398-5wot7tix 22 34 as as RB cord-010398-5wot7tix 22 35 well well RB cord-010398-5wot7tix 22 36 as as IN cord-010398-5wot7tix 22 37 evidence evidence NN cord-010398-5wot7tix 22 38 of of IN cord-010398-5wot7tix 22 39 elevated elevated JJ cord-010398-5wot7tix 22 40 antibodies antibody NNS cord-010398-5wot7tix 22 41 to to IN cord-010398-5wot7tix 22 42 a a DT cord-010398-5wot7tix 22 43 number number NN cord-010398-5wot7tix 22 44 of of IN cord-010398-5wot7tix 22 45 different different JJ cord-010398-5wot7tix 22 46 viral viral JJ cord-010398-5wot7tix 22 47 pathogens pathogen NNS cord-010398-5wot7tix 22 48 , , , cord-010398-5wot7tix 22 49 leading lead VBG cord-010398-5wot7tix 22 50 to to IN cord-010398-5wot7tix 22 51 the the DT cord-010398-5wot7tix 22 52 theory theory NN cord-010398-5wot7tix 22 53 that that IN cord-010398-5wot7tix 22 54 there there EX cord-010398-5wot7tix 22 55 was be VBD cord-010398-5wot7tix 22 56 an an DT cord-010398-5wot7tix 22 57 active active JJ cord-010398-5wot7tix 22 58 viral viral JJ cord-010398-5wot7tix 22 59 illness illness NN cord-010398-5wot7tix 22 60 that that WDT cord-010398-5wot7tix 22 61 was be VBD cord-010398-5wot7tix 22 62 causing cause VBG cord-010398-5wot7tix 22 63 these these DT cord-010398-5wot7tix 22 64 symptoms symptom NNS cord-010398-5wot7tix 22 65 . . . cord-010398-5wot7tix 23 1 However however RB cord-010398-5wot7tix 23 2 , , , cord-010398-5wot7tix 23 3 after after IN cord-010398-5wot7tix 23 4 extensive extensive JJ cord-010398-5wot7tix 23 5 subsequent subsequent JJ cord-010398-5wot7tix 23 6 investigations investigation NNS cord-010398-5wot7tix 23 7 of of IN cord-010398-5wot7tix 23 8 this this DT cord-010398-5wot7tix 23 9 group group NN cord-010398-5wot7tix 23 10 of of IN cord-010398-5wot7tix 23 11 patients patient NNS cord-010398-5wot7tix 23 12 , , , cord-010398-5wot7tix 23 13 as as RB cord-010398-5wot7tix 23 14 well well RB cord-010398-5wot7tix 23 15 as as IN cord-010398-5wot7tix 23 16 many many JJ cord-010398-5wot7tix 23 17 other other JJ cord-010398-5wot7tix 23 18 clusters cluster NNS cord-010398-5wot7tix 23 19 of of IN cord-010398-5wot7tix 23 20 patients patient NNS cord-010398-5wot7tix 23 21 initially initially RB cord-010398-5wot7tix 23 22 identified identify VBN cord-010398-5wot7tix 23 23 as as IN cord-010398-5wot7tix 23 24 part part NN cord-010398-5wot7tix 23 25 of of IN cord-010398-5wot7tix 23 26 an an DT cord-010398-5wot7tix 23 27 " " `` cord-010398-5wot7tix 23 28 epidemic epidemic NN cord-010398-5wot7tix 23 29 " " '' cord-010398-5wot7tix 23 30 of of IN cord-010398-5wot7tix 23 31 fatiguing fatiguing JJ cord-010398-5wot7tix 23 32 illness illness NN cord-010398-5wot7tix 23 33 , , , cord-010398-5wot7tix 23 34 it -PRON- PRP cord-010398-5wot7tix 23 35 became become VBD cord-010398-5wot7tix 23 36 increasingly increasingly RB cord-010398-5wot7tix 23 37 clear clear JJ cord-010398-5wot7tix 23 38 that that IN cord-010398-5wot7tix 23 39 neither neither CC cord-010398-5wot7tix 23 40 this this DT cord-010398-5wot7tix 23 41 symptom symptom NN cord-010398-5wot7tix 23 42 complex complex NN cord-010398-5wot7tix 23 43 nor nor CC cord-010398-5wot7tix 23 44 any any DT cord-010398-5wot7tix 23 45 immunological immunological JJ cord-010398-5wot7tix 23 46 abnormalities abnormality NNS cord-010398-5wot7tix 23 47 identified identify VBN cord-010398-5wot7tix 23 48 were be VBD cord-010398-5wot7tix 23 49 specific specific JJ cord-010398-5wot7tix 23 50 to to IN cord-010398-5wot7tix 23 51 any any DT cord-010398-5wot7tix 23 52 single single JJ cord-010398-5wot7tix 23 53 epidemic epidemic NN cord-010398-5wot7tix 23 54 , , , cord-010398-5wot7tix 23 55 or or CC cord-010398-5wot7tix 23 56 single single JJ cord-010398-5wot7tix 23 57 pathogen pathogen NN cord-010398-5wot7tix 23 58 [ [ -LRB- cord-010398-5wot7tix 23 59 2 2 CD cord-010398-5wot7tix 23 60 ] ] -RRB- cord-010398-5wot7tix 23 61 [ [ -LRB- cord-010398-5wot7tix 23 62 3 3 CD cord-010398-5wot7tix 23 63 ] ] -RRB- cord-010398-5wot7tix 23 64 [ [ -LRB- cord-010398-5wot7tix 23 65 4 4 CD cord-010398-5wot7tix 23 66 ] ] -RRB- cord-010398-5wot7tix 23 67 [ [ -LRB- cord-010398-5wot7tix 23 68 5 5 CD cord-010398-5wot7tix 23 69 ] ] -RRB- cord-010398-5wot7tix 23 70 . . . cord-010398-5wot7tix 24 1 Other other JJ cord-010398-5wot7tix 24 2 terms term NNS cord-010398-5wot7tix 24 3 have have VBP cord-010398-5wot7tix 24 4 been be VBN cord-010398-5wot7tix 24 5 used use VBN cord-010398-5wot7tix 24 6 to to TO cord-010398-5wot7tix 24 7 describe describe VB cord-010398-5wot7tix 24 8 patients patient NNS cord-010398-5wot7tix 24 9 with with IN cord-010398-5wot7tix 24 10 what what WP cord-010398-5wot7tix 24 11 we -PRON- PRP cord-010398-5wot7tix 24 12 now now RB cord-010398-5wot7tix 24 13 call call VBP cord-010398-5wot7tix 24 14 CFS CFS NNP cord-010398-5wot7tix 24 15 . . . cord-010398-5wot7tix 25 1 Some some DT cord-010398-5wot7tix 25 2 of of IN cord-010398-5wot7tix 25 3 these these DT cord-010398-5wot7tix 25 4 inaccurately inaccurately RB cord-010398-5wot7tix 25 5 characterized characterize VBN cord-010398-5wot7tix 25 6 this this DT cord-010398-5wot7tix 25 7 condition condition NN cord-010398-5wot7tix 25 8 to to TO cord-010398-5wot7tix 25 9 be be VB cord-010398-5wot7tix 25 10 the the DT cord-010398-5wot7tix 25 11 result result NN cord-010398-5wot7tix 25 12 of of IN cord-010398-5wot7tix 25 13 a a DT cord-010398-5wot7tix 25 14 single single JJ cord-010398-5wot7tix 25 15 common common JJ cord-010398-5wot7tix 25 16 pathogen pathogen NN cord-010398-5wot7tix 25 17 , , , cord-010398-5wot7tix 25 18 or or CC cord-010398-5wot7tix 25 19 ubiquitous ubiquitous JJ cord-010398-5wot7tix 25 20 organisms organism NNS cord-010398-5wot7tix 25 21 , , , cord-010398-5wot7tix 25 22 hence hence RB cord-010398-5wot7tix 25 23 , , , cord-010398-5wot7tix 25 24 the the DT cord-010398-5wot7tix 25 25 names name NNS cord-010398-5wot7tix 25 26 chronic chronic JJ cord-010398-5wot7tix 25 27 Epstein Epstein NNP cord-010398-5wot7tix 25 28 - - HYPH cord-010398-5wot7tix 25 29 Barr Barr NNP cord-010398-5wot7tix 25 30 virus virus NN cord-010398-5wot7tix 25 31 ( ( -LRB- cord-010398-5wot7tix 25 32 EBV EBV NNP cord-010398-5wot7tix 25 33 ) ) -RRB- cord-010398-5wot7tix 25 34 , , , cord-010398-5wot7tix 25 35 mycoplasma mycoplasma NN cord-010398-5wot7tix 25 36 , , , cord-010398-5wot7tix 25 37 or or CC cord-010398-5wot7tix 25 38 yeast yeast NN cord-010398-5wot7tix 25 39 infections infection NNS cord-010398-5wot7tix 25 40 [ [ -LRB- cord-010398-5wot7tix 25 41 6 6 CD cord-010398-5wot7tix 25 42 ] ] -RRB- cord-010398-5wot7tix 25 43 [ [ -LRB- cord-010398-5wot7tix 25 44 7 7 CD cord-010398-5wot7tix 25 45 ] ] -RRB- cord-010398-5wot7tix 25 46 [ [ -LRB- cord-010398-5wot7tix 25 47 8 8 CD cord-010398-5wot7tix 25 48 ] ] -RRB- cord-010398-5wot7tix 25 49 . . . cord-010398-5wot7tix 26 1 Finally finally RB cord-010398-5wot7tix 26 2 , , , cord-010398-5wot7tix 26 3 we -PRON- PRP cord-010398-5wot7tix 26 4 will will MD cord-010398-5wot7tix 26 5 reject reject VB cord-010398-5wot7tix 26 6 the the DT cord-010398-5wot7tix 26 7 use use NN cord-010398-5wot7tix 26 8 of of IN cord-010398-5wot7tix 26 9 terms term NNS cord-010398-5wot7tix 26 10 not not RB cord-010398-5wot7tix 26 11 supported support VBN cord-010398-5wot7tix 26 12 by by IN cord-010398-5wot7tix 26 13 pathophysiological pathophysiological JJ cord-010398-5wot7tix 26 14 evidence evidence NN cord-010398-5wot7tix 26 15 , , , cord-010398-5wot7tix 26 16 such such JJ cord-010398-5wot7tix 26 17 as as IN cord-010398-5wot7tix 26 18 myalgic myalgic JJ cord-010398-5wot7tix 26 19 encephalomyelitis encephalomyelitis NN cord-010398-5wot7tix 26 20 . . . cord-010398-5wot7tix 27 1 A a DT cord-010398-5wot7tix 27 2 recurring recurring JJ cord-010398-5wot7tix 27 3 problem problem NN cord-010398-5wot7tix 27 4 in in IN cord-010398-5wot7tix 27 5 the the DT cord-010398-5wot7tix 27 6 history history NN cord-010398-5wot7tix 27 7 of of IN cord-010398-5wot7tix 27 8 this this DT cord-010398-5wot7tix 27 9 illness illness NN cord-010398-5wot7tix 27 10 is be VBZ cord-010398-5wot7tix 27 11 that that IN cord-010398-5wot7tix 27 12 causality causality NN cord-010398-5wot7tix 27 13 has have VBZ cord-010398-5wot7tix 27 14 not not RB cord-010398-5wot7tix 27 15 yet yet RB cord-010398-5wot7tix 27 16 been be VBN cord-010398-5wot7tix 27 17 established establish VBN cord-010398-5wot7tix 27 18 but but CC cord-010398-5wot7tix 27 19 is be VBZ cord-010398-5wot7tix 27 20 asserted assert VBN cord-010398-5wot7tix 27 21 on on IN cord-010398-5wot7tix 27 22 the the DT cord-010398-5wot7tix 27 23 basis basis NN cord-010398-5wot7tix 27 24 of of IN cord-010398-5wot7tix 27 25 cross cross JJ cord-010398-5wot7tix 27 26 - - JJ cord-010398-5wot7tix 27 27 sectional sectional JJ cord-010398-5wot7tix 27 28 studies study NNS cord-010398-5wot7tix 27 29 or or CC cord-010398-5wot7tix 27 30 without without IN cord-010398-5wot7tix 27 31 appropriate appropriate JJ cord-010398-5wot7tix 27 32 control control NN cord-010398-5wot7tix 27 33 groups group NNS cord-010398-5wot7tix 27 34 . . . cord-010398-5wot7tix 28 1 These these DT cord-010398-5wot7tix 28 2 assertions assertion NNS cord-010398-5wot7tix 28 3 are be VBP cord-010398-5wot7tix 28 4 almost almost RB cord-010398-5wot7tix 28 5 incorrect incorrect JJ cord-010398-5wot7tix 28 6 , , , cord-010398-5wot7tix 28 7 in in IN cord-010398-5wot7tix 28 8 part part NN cord-010398-5wot7tix 28 9 because because IN cord-010398-5wot7tix 28 10 both both CC cord-010398-5wot7tix 28 11 the the DT cord-010398-5wot7tix 28 12 symptom symptom NN cord-010398-5wot7tix 28 13 complexes complex NNS cord-010398-5wot7tix 28 14 and and CC cord-010398-5wot7tix 28 15 objective objective JJ cord-010398-5wot7tix 28 16 " " `` cord-010398-5wot7tix 28 17 abnormalities abnormality NNS cord-010398-5wot7tix 28 18 " " '' cord-010398-5wot7tix 28 19 used use VBN cord-010398-5wot7tix 28 20 to to TO cord-010398-5wot7tix 28 21 infer infer VB cord-010398-5wot7tix 28 22 cause cause NN cord-010398-5wot7tix 28 23 ( ( -LRB- cord-010398-5wot7tix 28 24 eg eg IN cord-010398-5wot7tix 28 25 , , , cord-010398-5wot7tix 28 26 immunological immunological JJ cord-010398-5wot7tix 28 27 , , , cord-010398-5wot7tix 28 28 neuroendocrine neuroendocrine JJ cord-010398-5wot7tix 28 29 , , , cord-010398-5wot7tix 28 30 imaging image VBG cord-010398-5wot7tix 28 31 findings finding NNS cord-010398-5wot7tix 28 32 ) ) -RRB- cord-010398-5wot7tix 28 33 are be VBP cord-010398-5wot7tix 28 34 very very RB cord-010398-5wot7tix 28 35 common common JJ cord-010398-5wot7tix 28 36 in in IN cord-010398-5wot7tix 28 37 the the DT cord-010398-5wot7tix 28 38 general general JJ cord-010398-5wot7tix 28 39 population population NN cord-010398-5wot7tix 28 40 [ [ -LRB- cord-010398-5wot7tix 28 41 9 9 CD cord-010398-5wot7tix 28 42 ] ] -RRB- cord-010398-5wot7tix 28 43 [ [ -LRB- cord-010398-5wot7tix 28 44 10 10 CD cord-010398-5wot7tix 28 45 ] ] -RRB- cord-010398-5wot7tix 28 46 [ [ -LRB- cord-010398-5wot7tix 28 47 11 11 CD cord-010398-5wot7tix 28 48 ] ] -RRB- cord-010398-5wot7tix 28 49 . . . cord-010398-5wot7tix 29 1 We -PRON- PRP cord-010398-5wot7tix 29 2 prefer prefer VBP cord-010398-5wot7tix 29 3 the the DT cord-010398-5wot7tix 29 4 terms term NNS cord-010398-5wot7tix 29 5 CFS cfs NN cord-010398-5wot7tix 29 6 and and CC cord-010398-5wot7tix 29 7 idiopathic idiopathic JJ cord-010398-5wot7tix 29 8 chronic chronic JJ cord-010398-5wot7tix 29 9 fatigue fatigue NN cord-010398-5wot7tix 29 10 ( ( -LRB- cord-010398-5wot7tix 29 11 ICF ICF NNP cord-010398-5wot7tix 29 12 ) ) -RRB- cord-010398-5wot7tix 29 13 because because IN cord-010398-5wot7tix 29 14 they -PRON- PRP cord-010398-5wot7tix 29 15 are be VBP cord-010398-5wot7tix 29 16 descriptive descriptive JJ cord-010398-5wot7tix 29 17 and and CC cord-010398-5wot7tix 29 18 do do VBP cord-010398-5wot7tix 29 19 not not RB cord-010398-5wot7tix 29 20 imply imply VB cord-010398-5wot7tix 29 21 underlying underlying JJ cord-010398-5wot7tix 29 22 etiologies etiology NNS cord-010398-5wot7tix 29 23 or or CC cord-010398-5wot7tix 29 24 triggers trigger NNS cord-010398-5wot7tix 29 25 . . . cord-010398-5wot7tix 30 1 Also also RB cord-010398-5wot7tix 30 2 , , , cord-010398-5wot7tix 30 3 these these DT cord-010398-5wot7tix 30 4 terms term NNS cord-010398-5wot7tix 30 5 are be VBP cord-010398-5wot7tix 30 6 consistent consistent JJ cord-010398-5wot7tix 30 7 with with IN cord-010398-5wot7tix 30 8 the the DT cord-010398-5wot7tix 30 9 views view NNS cord-010398-5wot7tix 30 10 held hold VBN cord-010398-5wot7tix 30 11 by by IN cord-010398-5wot7tix 30 12 practitioners practitioner NNS cord-010398-5wot7tix 30 13 who who WP cord-010398-5wot7tix 30 14 treat treat VBP cord-010398-5wot7tix 30 15 these these DT cord-010398-5wot7tix 30 16 patients patient NNS cord-010398-5wot7tix 30 17 and and CC cord-010398-5wot7tix 30 18 researchers researcher NNS cord-010398-5wot7tix 30 19 who who WP cord-010398-5wot7tix 30 20 study study VBP cord-010398-5wot7tix 30 21 them -PRON- PRP cord-010398-5wot7tix 30 22 that that IN cord-010398-5wot7tix 30 23 CFS CFS NNP cord-010398-5wot7tix 30 24 / / SYM cord-010398-5wot7tix 30 25 ICF ICF NNP cord-010398-5wot7tix 30 26 is be VBZ cord-010398-5wot7tix 30 27 a a DT cord-010398-5wot7tix 30 28 very very RB cord-010398-5wot7tix 30 29 heterogeneous heterogeneous JJ cord-010398-5wot7tix 30 30 disorder disorder NN cord-010398-5wot7tix 30 31 that that WDT cord-010398-5wot7tix 30 32 , , , cord-010398-5wot7tix 30 33 like like IN cord-010398-5wot7tix 30 34 many many JJ cord-010398-5wot7tix 30 35 other other JJ cord-010398-5wot7tix 30 36 chronic chronic JJ cord-010398-5wot7tix 30 37 medical medical JJ cord-010398-5wot7tix 30 38 illnesses illness NNS cord-010398-5wot7tix 30 39 ( ( -LRB- cord-010398-5wot7tix 30 40 eg eg IN cord-010398-5wot7tix 30 41 , , , cord-010398-5wot7tix 30 42 hypertension hypertension NN cord-010398-5wot7tix 30 43 , , , cord-010398-5wot7tix 30 44 diabetes diabetes NN cord-010398-5wot7tix 30 45 ) ) -RRB- cord-010398-5wot7tix 30 46 , , , cord-010398-5wot7tix 30 47 has have VBZ cord-010398-5wot7tix 30 48 a a DT cord-010398-5wot7tix 30 49 multiplicity multiplicity NN cord-010398-5wot7tix 30 50 of of IN cord-010398-5wot7tix 30 51 etiologic etiologic JJ cord-010398-5wot7tix 30 52 and and CC cord-010398-5wot7tix 30 53 pathogenic pathogenic JJ cord-010398-5wot7tix 30 54 factors factor NNS cord-010398-5wot7tix 30 55 that that WDT cord-010398-5wot7tix 30 56 contribute contribute VBP cord-010398-5wot7tix 30 57 to to IN cord-010398-5wot7tix 30 58 the the DT cord-010398-5wot7tix 30 59 expression expression NN cord-010398-5wot7tix 30 60 of of IN cord-010398-5wot7tix 30 61 the the DT cord-010398-5wot7tix 30 62 syndrome syndrome NN cord-010398-5wot7tix 30 63 [ [ -LRB- cord-010398-5wot7tix 30 64 12 12 CD cord-010398-5wot7tix 30 65 , , , cord-010398-5wot7tix 30 66 13 13 CD cord-010398-5wot7tix 30 67 ] ] -RRB- cord-010398-5wot7tix 30 68 . . . cord-010398-5wot7tix 31 1 A a DT cord-010398-5wot7tix 31 2 1994 1994 CD cord-010398-5wot7tix 31 3 CDC CDC NNP cord-010398-5wot7tix 31 4 case case NN cord-010398-5wot7tix 31 5 definition definition NN cord-010398-5wot7tix 31 6 for for IN cord-010398-5wot7tix 31 7 CFS CFS NNP cord-010398-5wot7tix 31 8 requires require VBZ cord-010398-5wot7tix 31 9 at at IN cord-010398-5wot7tix 31 10 least least JJS cord-010398-5wot7tix 31 11 6 6 CD cord-010398-5wot7tix 31 12 months month NNS cord-010398-5wot7tix 31 13 of of IN cord-010398-5wot7tix 31 14 persistent persistent JJ cord-010398-5wot7tix 31 15 fatigue fatigue NN cord-010398-5wot7tix 31 16 that that WDT cord-010398-5wot7tix 31 17 substantially substantially RB cord-010398-5wot7tix 31 18 reduces reduce VBZ cord-010398-5wot7tix 31 19 the the DT cord-010398-5wot7tix 31 20 person person NN cord-010398-5wot7tix 31 21 's 's POS cord-010398-5wot7tix 31 22 level level NN cord-010398-5wot7tix 31 23 of of IN cord-010398-5wot7tix 31 24 activity activity NN cord-010398-5wot7tix 31 25 . . . cord-010398-5wot7tix 32 1 In in IN cord-010398-5wot7tix 32 2 addition addition NN cord-010398-5wot7tix 32 3 , , , cord-010398-5wot7tix 32 4 4 4 CD cord-010398-5wot7tix 32 5 or or CC cord-010398-5wot7tix 32 6 more more JJR cord-010398-5wot7tix 32 7 of of IN cord-010398-5wot7tix 32 8 the the DT cord-010398-5wot7tix 32 9 following follow VBG cord-010398-5wot7tix 32 10 symptoms symptom NNS cord-010398-5wot7tix 32 11 must must MD cord-010398-5wot7tix 32 12 occur occur VB cord-010398-5wot7tix 32 13 with with IN cord-010398-5wot7tix 32 14 fatigue fatigue NN cord-010398-5wot7tix 32 15 in in IN cord-010398-5wot7tix 32 16 a a DT cord-010398-5wot7tix 32 17 6-month 6-month CD cord-010398-5wot7tix 32 18 period period NN cord-010398-5wot7tix 32 19 : : : cord-010398-5wot7tix 32 20 impaired impair VBN cord-010398-5wot7tix 32 21 memory memory NN cord-010398-5wot7tix 32 22 or or CC cord-010398-5wot7tix 32 23 concentration concentration NN cord-010398-5wot7tix 32 24 , , , cord-010398-5wot7tix 32 25 sore sore JJ cord-010398-5wot7tix 32 26 throat throat NN cord-010398-5wot7tix 32 27 , , , cord-010398-5wot7tix 32 28 tender tender JJ cord-010398-5wot7tix 32 29 glands gland NNS cord-010398-5wot7tix 32 30 , , , cord-010398-5wot7tix 32 31 aching ache VBG cord-010398-5wot7tix 32 32 or or CC cord-010398-5wot7tix 32 33 stiff stiff JJ cord-010398-5wot7tix 32 34 muscles muscle NNS cord-010398-5wot7tix 32 35 , , , cord-010398-5wot7tix 32 36 multijoint multijoint NN cord-010398-5wot7tix 32 37 pain pain NN cord-010398-5wot7tix 32 38 , , , cord-010398-5wot7tix 32 39 new new JJ cord-010398-5wot7tix 32 40 headaches headache NNS cord-010398-5wot7tix 32 41 , , , cord-010398-5wot7tix 32 42 unrefreshing unrefreshing NN cord-010398-5wot7tix 32 43 sleep sleep NN cord-010398-5wot7tix 32 44 , , , cord-010398-5wot7tix 32 45 and and CC cord-010398-5wot7tix 32 46 postexertional postexertional JJ cord-010398-5wot7tix 32 47 fatigue fatigue NN cord-010398-5wot7tix 32 48 [ [ -LRB- cord-010398-5wot7tix 32 49 14 14 CD cord-010398-5wot7tix 32 50 ] ] -RRB- cord-010398-5wot7tix 32 51 . . . cord-010398-5wot7tix 33 1 Medical medical JJ cord-010398-5wot7tix 33 2 conditions condition NNS cord-010398-5wot7tix 33 3 that that WDT cord-010398-5wot7tix 33 4 may may MD cord-010398-5wot7tix 33 5 explain explain VB cord-010398-5wot7tix 33 6 the the DT cord-010398-5wot7tix 33 7 prolonged prolonged JJ cord-010398-5wot7tix 33 8 fatigue fatigue NN cord-010398-5wot7tix 33 9 as as RB cord-010398-5wot7tix 33 10 well well RB cord-010398-5wot7tix 33 11 as as IN cord-010398-5wot7tix 33 12 a a DT cord-010398-5wot7tix 33 13 number number NN cord-010398-5wot7tix 33 14 of of IN cord-010398-5wot7tix 33 15 psychiatric psychiatric JJ cord-010398-5wot7tix 33 16 diagnoses diagnosis NNS cord-010398-5wot7tix 33 17 ( ( -LRB- cord-010398-5wot7tix 33 18 eg eg IN cord-010398-5wot7tix 33 19 , , , cord-010398-5wot7tix 33 20 eating eat VBG cord-010398-5wot7tix 33 21 disorders disorder NNS cord-010398-5wot7tix 33 22 , , , cord-010398-5wot7tix 33 23 psychotic psychotic JJ cord-010398-5wot7tix 33 24 disorders disorder NNS cord-010398-5wot7tix 33 25 , , , cord-010398-5wot7tix 33 26 bipolar bipolar JJ cord-010398-5wot7tix 33 27 disorder disorder NN cord-010398-5wot7tix 33 28 , , , cord-010398-5wot7tix 33 29 melancholic melancholic JJ cord-010398-5wot7tix 33 30 depression depression NN cord-010398-5wot7tix 33 31 , , , cord-010398-5wot7tix 33 32 and and CC cord-010398-5wot7tix 33 33 substance substance NN cord-010398-5wot7tix 33 34 abuse abuse NN cord-010398-5wot7tix 33 35 within within IN cord-010398-5wot7tix 33 36 2 2 CD cord-010398-5wot7tix 33 37 years year NNS cord-010398-5wot7tix 33 38 of of IN cord-010398-5wot7tix 33 39 the the DT cord-010398-5wot7tix 33 40 onset onset NN cord-010398-5wot7tix 33 41 of of IN cord-010398-5wot7tix 33 42 fatigue fatigue NN cord-010398-5wot7tix 33 43 ) ) -RRB- cord-010398-5wot7tix 33 44 exclude exclude VB cord-010398-5wot7tix 33 45 a a DT cord-010398-5wot7tix 33 46 patient patient NN cord-010398-5wot7tix 33 47 from from IN cord-010398-5wot7tix 33 48 the the DT cord-010398-5wot7tix 33 49 diagnosis diagnosis NN cord-010398-5wot7tix 33 50 of of IN cord-010398-5wot7tix 33 51 CFS CFS NNP cord-010398-5wot7tix 33 52 . . . cord-010398-5wot7tix 34 1 A a DT cord-010398-5wot7tix 34 2 notable notable JJ cord-010398-5wot7tix 34 3 feature feature NN cord-010398-5wot7tix 34 4 of of IN cord-010398-5wot7tix 34 5 the the DT cord-010398-5wot7tix 34 6 CDC CDC NNP cord-010398-5wot7tix 34 7 case case NN cord-010398-5wot7tix 34 8 definition definition NN cord-010398-5wot7tix 34 9 is be VBZ cord-010398-5wot7tix 34 10 that that IN cord-010398-5wot7tix 34 11 many many JJ cord-010398-5wot7tix 34 12 nonpsychotic nonpsychotic JJ cord-010398-5wot7tix 34 13 psychiatric psychiatric JJ cord-010398-5wot7tix 34 14 disorders disorder NNS cord-010398-5wot7tix 34 15 are be VBP cord-010398-5wot7tix 34 16 not not RB cord-010398-5wot7tix 34 17 exclusionary exclusionary JJ cord-010398-5wot7tix 34 18 for for IN cord-010398-5wot7tix 34 19 the the DT cord-010398-5wot7tix 34 20 diagnosis diagnosis NN cord-010398-5wot7tix 34 21 of of IN cord-010398-5wot7tix 34 22 CFS CFS NNP cord-010398-5wot7tix 34 23 . . . cord-010398-5wot7tix 35 1 Those those DT cord-010398-5wot7tix 35 2 who who WP cord-010398-5wot7tix 35 3 do do VBP cord-010398-5wot7tix 35 4 not not RB cord-010398-5wot7tix 35 5 meet meet VB cord-010398-5wot7tix 35 6 the the DT cord-010398-5wot7tix 35 7 fatigue fatigue NN cord-010398-5wot7tix 35 8 severity severity NN cord-010398-5wot7tix 35 9 or or CC cord-010398-5wot7tix 35 10 symptom symptom NN cord-010398-5wot7tix 35 11 criteria criterion NNS cord-010398-5wot7tix 35 12 can can MD cord-010398-5wot7tix 35 13 be be VB cord-010398-5wot7tix 35 14 given give VBN cord-010398-5wot7tix 35 15 a a DT cord-010398-5wot7tix 35 16 diagnosis diagnosis NN cord-010398-5wot7tix 35 17 of of IN cord-010398-5wot7tix 35 18 ICF ICF NNP cord-010398-5wot7tix 35 19 . . . cord-010398-5wot7tix 36 1 Although although IN cord-010398-5wot7tix 36 2 the the DT cord-010398-5wot7tix 36 3 case case NN cord-010398-5wot7tix 36 4 definition definition NN cord-010398-5wot7tix 36 5 for for IN cord-010398-5wot7tix 36 6 CFS CFS NNP cord-010398-5wot7tix 36 7 has have VBZ cord-010398-5wot7tix 36 8 been be VBN cord-010398-5wot7tix 36 9 in in IN cord-010398-5wot7tix 36 10 place place NN cord-010398-5wot7tix 36 11 for for IN cord-010398-5wot7tix 36 12 some some DT cord-010398-5wot7tix 36 13 time time NN cord-010398-5wot7tix 36 14 [ [ -LRB- cord-010398-5wot7tix 36 15 14 14 CD cord-010398-5wot7tix 36 16 ] ] -RRB- cord-010398-5wot7tix 36 17 , , , cord-010398-5wot7tix 36 18 there there EX cord-010398-5wot7tix 36 19 is be VBZ cord-010398-5wot7tix 36 20 an an DT cord-010398-5wot7tix 36 21 unexplainable unexplainable JJ cord-010398-5wot7tix 36 22 difference difference NN cord-010398-5wot7tix 36 23 between between IN cord-010398-5wot7tix 36 24 findings finding NNS cord-010398-5wot7tix 36 25 of of IN cord-010398-5wot7tix 36 26 older old JJR cord-010398-5wot7tix 36 27 epidemiological epidemiological JJ cord-010398-5wot7tix 36 28 studies study NNS cord-010398-5wot7tix 36 29 that that WDT cord-010398-5wot7tix 36 30 suggested suggest VBD cord-010398-5wot7tix 36 31 that that IN cord-010398-5wot7tix 36 32 this this DT cord-010398-5wot7tix 36 33 was be VBD cord-010398-5wot7tix 36 34 a a DT cord-010398-5wot7tix 36 35 very very RB cord-010398-5wot7tix 36 36 rare rare JJ cord-010398-5wot7tix 36 37 ( ( -LRB- cord-010398-5wot7tix 36 38 ie ie FW cord-010398-5wot7tix 36 39 , , , cord-010398-5wot7tix 36 40 1 1 CD cord-010398-5wot7tix 36 41 % % NN cord-010398-5wot7tix 36 42 of of IN cord-010398-5wot7tix 36 43 the the DT cord-010398-5wot7tix 36 44 population population NN cord-010398-5wot7tix 36 45 ) ) -RRB- cord-010398-5wot7tix 36 46 disorder disorder NN cord-010398-5wot7tix 36 47 , , , cord-010398-5wot7tix 36 48 and and CC cord-010398-5wot7tix 36 49 newer new JJR cord-010398-5wot7tix 36 50 studies study NNS cord-010398-5wot7tix 36 51 in in IN cord-010398-5wot7tix 36 52 which which WDT cord-010398-5wot7tix 36 53 the the DT cord-010398-5wot7tix 36 54 authors author NNS cord-010398-5wot7tix 36 55 all all DT cord-010398-5wot7tix 36 56 agree agree VBP cord-010398-5wot7tix 36 57 that that IN cord-010398-5wot7tix 36 58 this this DT cord-010398-5wot7tix 36 59 occurs occur VBZ cord-010398-5wot7tix 36 60 in in RP cord-010398-5wot7tix 36 61 at at RB cord-010398-5wot7tix 36 62 least least JJS cord-010398-5wot7tix 36 63 1 1 CD cord-010398-5wot7tix 36 64 % % NN cord-010398-5wot7tix 36 65 to to TO cord-010398-5wot7tix 36 66 3 3 CD cord-010398-5wot7tix 36 67 % % NN cord-010398-5wot7tix 36 68 of of IN cord-010398-5wot7tix 36 69 the the DT cord-010398-5wot7tix 36 70 population population NN cord-010398-5wot7tix 36 71 [ [ -LRB- cord-010398-5wot7tix 36 72 15 15 CD cord-010398-5wot7tix 36 73 ] ] -RRB- cord-010398-5wot7tix 36 74 . . . cord-010398-5wot7tix 37 1 These these DT cord-010398-5wot7tix 37 2 data datum NNS cord-010398-5wot7tix 37 3 from from IN cord-010398-5wot7tix 37 4 the the DT cord-010398-5wot7tix 37 5 newer new JJR cord-010398-5wot7tix 37 6 studies study NNS cord-010398-5wot7tix 37 7 are be VBP cord-010398-5wot7tix 37 8 supported support VBN cord-010398-5wot7tix 37 9 by by IN cord-010398-5wot7tix 37 10 the the DT cord-010398-5wot7tix 37 11 2 2 CD cord-010398-5wot7tix 37 12 % % NN cord-010398-5wot7tix 37 13 to to TO cord-010398-5wot7tix 37 14 4 4 CD cord-010398-5wot7tix 37 15 % % NN cord-010398-5wot7tix 37 16 prevalence prevalence NN cord-010398-5wot7tix 37 17 data datum NNS cord-010398-5wot7tix 37 18 reported report VBN cord-010398-5wot7tix 37 19 for for IN cord-010398-5wot7tix 37 20 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 37 21 ( ( -LRB- cord-010398-5wot7tix 37 22 FM FM NNP cord-010398-5wot7tix 37 23 ) ) -RRB- cord-010398-5wot7tix 37 24 , , , cord-010398-5wot7tix 37 25 in in IN cord-010398-5wot7tix 37 26 which which WDT cord-010398-5wot7tix 37 27 one one CD cord-010398-5wot7tix 37 28 half half NN cord-010398-5wot7tix 37 29 of of IN cord-010398-5wot7tix 37 30 patients patient NNS cord-010398-5wot7tix 37 31 meet meet VBP cord-010398-5wot7tix 37 32 criteria criterion NNS cord-010398-5wot7tix 37 33 for for IN cord-010398-5wot7tix 37 34 CFS CFS NNP cord-010398-5wot7tix 37 35 [ [ -LRB- cord-010398-5wot7tix 37 36 16 16 CD cord-010398-5wot7tix 37 37 ] ] -RRB- cord-010398-5wot7tix 38 1 [ [ -LRB- cord-010398-5wot7tix 38 2 17 17 CD cord-010398-5wot7tix 38 3 ] ] -RRB- cord-010398-5wot7tix 38 4 [ [ -LRB- cord-010398-5wot7tix 38 5 18 18 CD cord-010398-5wot7tix 38 6 ] ] -RRB- cord-010398-5wot7tix 38 7 . . . cord-010398-5wot7tix 39 1 Both both DT cord-010398-5wot7tix 39 2 the the DT cord-010398-5wot7tix 39 3 prevalence prevalence NN cord-010398-5wot7tix 39 4 rates rate NNS cord-010398-5wot7tix 39 5 of of IN cord-010398-5wot7tix 39 6 CFS cfs NN cord-010398-5wot7tix 39 7 at at IN cord-010398-5wot7tix 39 8 1 1 CD cord-010398-5wot7tix 39 9 % % NN cord-010398-5wot7tix 39 10 to to TO cord-010398-5wot7tix 39 11 3 3 CD cord-010398-5wot7tix 39 12 % % NN cord-010398-5wot7tix 39 13 and and CC cord-010398-5wot7tix 39 14 ICF ICF NNP cord-010398-5wot7tix 39 15 at at IN cord-010398-5wot7tix 39 16 5 5 CD cord-010398-5wot7tix 39 17 % % NN cord-010398-5wot7tix 39 18 to to TO cord-010398-5wot7tix 39 19 10 10 CD cord-010398-5wot7tix 39 20 % % NN cord-010398-5wot7tix 39 21 are be VBP cord-010398-5wot7tix 39 22 remarkably remarkably RB cord-010398-5wot7tix 39 23 consistent consistent JJ cord-010398-5wot7tix 39 24 across across IN cord-010398-5wot7tix 39 25 many many JJ cord-010398-5wot7tix 39 26 different different JJ cord-010398-5wot7tix 39 27 cultures culture NNS cord-010398-5wot7tix 39 28 and and CC cord-010398-5wot7tix 39 29 countries country NNS cord-010398-5wot7tix 39 30 , , , cord-010398-5wot7tix 39 31 including include VBG cord-010398-5wot7tix 39 32 the the DT cord-010398-5wot7tix 39 33 United United NNP cord-010398-5wot7tix 39 34 States States NNP cord-010398-5wot7tix 39 35 , , , cord-010398-5wot7tix 39 36 United United NNP cord-010398-5wot7tix 39 37 Kingdom Kingdom NNP cord-010398-5wot7tix 39 38 , , , cord-010398-5wot7tix 39 39 Australia Australia NNP cord-010398-5wot7tix 39 40 , , , cord-010398-5wot7tix 39 41 Brazil Brazil NNP cord-010398-5wot7tix 39 42 , , , cord-010398-5wot7tix 39 43 and and CC cord-010398-5wot7tix 39 44 Nigeria Nigeria NNP cord-010398-5wot7tix 39 45 [ [ -LRB- cord-010398-5wot7tix 39 46 19 19 CD cord-010398-5wot7tix 39 47 ] ] -RRB- cord-010398-5wot7tix 39 48 [ [ -LRB- cord-010398-5wot7tix 39 49 20 20 CD cord-010398-5wot7tix 39 50 ] ] -RRB- cord-010398-5wot7tix 39 51 [ [ -LRB- cord-010398-5wot7tix 39 52 21 21 CD cord-010398-5wot7tix 39 53 ] ] -RRB- cord-010398-5wot7tix 39 54 [ [ -LRB- cord-010398-5wot7tix 39 55 22 22 CD cord-010398-5wot7tix 39 56 ] ] -RRB- cord-010398-5wot7tix 39 57 . . . cord-010398-5wot7tix 40 1 The the DT cord-010398-5wot7tix 40 2 authors author NNS cord-010398-5wot7tix 40 3 of of IN cord-010398-5wot7tix 40 4 a a DT cord-010398-5wot7tix 40 5 recent recent JJ cord-010398-5wot7tix 40 6 study study NN cord-010398-5wot7tix 40 7 collected collect VBD cord-010398-5wot7tix 40 8 relevant relevant JJ cord-010398-5wot7tix 40 9 demographic demographic JJ cord-010398-5wot7tix 40 10 , , , cord-010398-5wot7tix 40 11 symptom symptom NN cord-010398-5wot7tix 40 12 , , , cord-010398-5wot7tix 40 13 and and CC cord-010398-5wot7tix 40 14 diagnostic diagnostic JJ cord-010398-5wot7tix 40 15 data datum NNS cord-010398-5wot7tix 40 16 from from IN cord-010398-5wot7tix 40 17 33 33 CD cord-010398-5wot7tix 40 18 studies study NNS cord-010398-5wot7tix 40 19 in in IN cord-010398-5wot7tix 40 20 21 21 CD cord-010398-5wot7tix 40 21 countries country NNS cord-010398-5wot7tix 40 22 . . . cord-010398-5wot7tix 41 1 The the DT cord-010398-5wot7tix 41 2 subjects subject NNS cord-010398-5wot7tix 41 3 had have VBD cord-010398-5wot7tix 41 4 fatigue fatigue NN cord-010398-5wot7tix 41 5 lasting last VBG cord-010398-5wot7tix 41 6 1 1 CD cord-010398-5wot7tix 41 7 to to IN cord-010398-5wot7tix 41 8 6 6 CD cord-010398-5wot7tix 41 9 months month NNS cord-010398-5wot7tix 41 10 ( ( -LRB- cord-010398-5wot7tix 41 11 prolonged prolong VBN cord-010398-5wot7tix 41 12 fatigue fatigue NN cord-010398-5wot7tix 41 13 ) ) -RRB- cord-010398-5wot7tix 41 14 , , , cord-010398-5wot7tix 41 15 longer long JJR cord-010398-5wot7tix 41 16 than than IN cord-010398-5wot7tix 41 17 6 6 CD cord-010398-5wot7tix 41 18 months month NNS cord-010398-5wot7tix 41 19 ( ( -LRB- cord-010398-5wot7tix 41 20 chronic chronic JJ cord-010398-5wot7tix 41 21 fatigue fatigue NN cord-010398-5wot7tix 41 22 ) ) -RRB- cord-010398-5wot7tix 41 23 , , , cord-010398-5wot7tix 41 24 or or CC cord-010398-5wot7tix 41 25 met meet VBD cord-010398-5wot7tix 41 26 diagnostic diagnostic JJ cord-010398-5wot7tix 41 27 criteria criterion NNS cord-010398-5wot7tix 41 28 for for IN cord-010398-5wot7tix 41 29 CFS CFS NNP cord-010398-5wot7tix 41 30 . . . cord-010398-5wot7tix 42 1 Data datum NNS cord-010398-5wot7tix 42 2 were be VBD cord-010398-5wot7tix 42 3 obtained obtain VBN cord-010398-5wot7tix 42 4 from from IN cord-010398-5wot7tix 42 5 37,724 37,724 CD cord-010398-5wot7tix 42 6 subjects subject NNS cord-010398-5wot7tix 42 7 ( ( -LRB- cord-010398-5wot7tix 42 8 n n NN cord-010398-5wot7tix 42 9 ϭ ϭ JJ cord-010398-5wot7tix 42 10 20,845 20,845 CD cord-010398-5wot7tix 42 11 female female NN cord-010398-5wot7tix 42 12 ; ; : cord-010398-5wot7tix 42 13 57 57 CD cord-010398-5wot7tix 42 14 % % NN cord-010398-5wot7tix 42 15 ) ) -RRB- cord-010398-5wot7tix 42 16 , , , cord-010398-5wot7tix 42 17 including include VBG cord-010398-5wot7tix 42 18 from from IN cord-010398-5wot7tix 42 19 population population NN cord-010398-5wot7tix 42 20 - - HYPH cord-010398-5wot7tix 42 21 based base VBN cord-010398-5wot7tix 42 22 studies study NNS cord-010398-5wot7tix 42 23 ( ( -LRB- cord-010398-5wot7tix 42 24 n n NNP cord-010398-5wot7tix 42 25 ϭ ϭ NNP cord-010398-5wot7tix 42 26 15,749 15,749 CD cord-010398-5wot7tix 42 27 , , , cord-010398-5wot7tix 42 28 42 42 CD cord-010398-5wot7tix 42 29 % % NN cord-010398-5wot7tix 42 30 ) ) -RRB- cord-010398-5wot7tix 42 31 , , , cord-010398-5wot7tix 42 32 studies study NNS cord-010398-5wot7tix 42 33 in in IN cord-010398-5wot7tix 42 34 primary primary JJ cord-010398-5wot7tix 42 35 care care NN cord-010398-5wot7tix 42 36 ( ( -LRB- cord-010398-5wot7tix 42 37 n n NN cord-010398-5wot7tix 42 38 ϭ ϭ NNP cord-010398-5wot7tix 42 39 19,472 19,472 CD cord-010398-5wot7tix 42 40 , , , cord-010398-5wot7tix 42 41 52 52 CD cord-010398-5wot7tix 42 42 % % NN cord-010398-5wot7tix 42 43 ) ) -RRB- cord-010398-5wot7tix 42 44 , , , cord-010398-5wot7tix 42 45 and and CC cord-010398-5wot7tix 42 46 secondary secondary JJ cord-010398-5wot7tix 42 47 or or CC cord-010398-5wot7tix 42 48 specialist specialist JJ cord-010398-5wot7tix 42 49 tertiary tertiary JJ cord-010398-5wot7tix 42 50 referral referral NN cord-010398-5wot7tix 42 51 clinics clinic NNS cord-010398-5wot7tix 42 52 ( ( -LRB- cord-010398-5wot7tix 42 53 n n NN cord-010398-5wot7tix 42 54 ϭ ϭ NNP cord-010398-5wot7tix 42 55 2503 2503 CD cord-010398-5wot7tix 42 56 , , , cord-010398-5wot7tix 42 57 7 7 CD cord-010398-5wot7tix 42 58 % % NN cord-010398-5wot7tix 42 59 ) ) -RRB- cord-010398-5wot7tix 42 60 . . . cord-010398-5wot7tix 43 1 A a DT cord-010398-5wot7tix 43 2 5-factor 5-factor CD cord-010398-5wot7tix 43 3 model model NN cord-010398-5wot7tix 43 4 of of IN cord-010398-5wot7tix 43 5 the the DT cord-010398-5wot7tix 43 6 key key JJ cord-010398-5wot7tix 43 7 symptom symptom NN cord-010398-5wot7tix 43 8 domains domain NNS cord-010398-5wot7tix 43 9 was be VBD cord-010398-5wot7tix 43 10 preferred prefer VBN cord-010398-5wot7tix 43 11 ( ( -LRB- cord-010398-5wot7tix 43 12 " " `` cord-010398-5wot7tix 43 13 musculoskeletal musculoskeletal JJ cord-010398-5wot7tix 43 14 pain/ pain/ CD cord-010398-5wot7tix 43 15 fatigue fatigue NN cord-010398-5wot7tix 43 16 , , , cord-010398-5wot7tix 43 17 " " '' cord-010398-5wot7tix 43 18 " " `` cord-010398-5wot7tix 43 19 neurocognitive neurocognitive JJ cord-010398-5wot7tix 43 20 difficulties difficulty NNS cord-010398-5wot7tix 43 21 , , , cord-010398-5wot7tix 43 22 " " '' cord-010398-5wot7tix 43 23 " " `` cord-010398-5wot7tix 43 24 inflammation inflammation NN cord-010398-5wot7tix 43 25 , , , cord-010398-5wot7tix 43 26 " " '' cord-010398-5wot7tix 43 27 " " `` cord-010398-5wot7tix 43 28 sleep sleep NN cord-010398-5wot7tix 43 29 disturbance disturbance NN cord-010398-5wot7tix 43 30 / / SYM cord-010398-5wot7tix 43 31 fatigue fatigue NN cord-010398-5wot7tix 43 32 , , , cord-010398-5wot7tix 43 33 " " '' cord-010398-5wot7tix 43 34 and and CC cord-010398-5wot7tix 43 35 " " `` cord-010398-5wot7tix 43 36 mood mood NN cord-010398-5wot7tix 43 37 disturbance disturbance NN cord-010398-5wot7tix 43 38 " " '' cord-010398-5wot7tix 43 39 ) ) -RRB- cord-010398-5wot7tix 43 40 and and CC cord-010398-5wot7tix 43 41 was be VBD cord-010398-5wot7tix 43 42 comparable comparable JJ cord-010398-5wot7tix 43 43 across across IN cord-010398-5wot7tix 43 44 subject subject JJ cord-010398-5wot7tix 43 45 groups group NNS cord-010398-5wot7tix 43 46 and and CC cord-010398-5wot7tix 43 47 settings setting NNS cord-010398-5wot7tix 43 48 [ [ -LRB- cord-010398-5wot7tix 43 49 19 19 CD cord-010398-5wot7tix 43 50 ] ] -RRB- cord-010398-5wot7tix 43 51 . . . cord-010398-5wot7tix 44 1 Although although IN cord-010398-5wot7tix 44 2 the the DT cord-010398-5wot7tix 44 3 core core NN cord-010398-5wot7tix 44 4 symptoms symptom NNS cord-010398-5wot7tix 44 5 and and CC cord-010398-5wot7tix 44 6 condition condition NN cord-010398-5wot7tix 44 7 are be VBP cord-010398-5wot7tix 44 8 very very RB cord-010398-5wot7tix 44 9 similar similar JJ cord-010398-5wot7tix 44 10 across across IN cord-010398-5wot7tix 44 11 countries country NNS cord-010398-5wot7tix 44 12 and and CC cord-010398-5wot7tix 44 13 cultures culture NNS cord-010398-5wot7tix 44 14 , , , cord-010398-5wot7tix 44 15 the the DT cord-010398-5wot7tix 44 16 likelihood likelihood NN cord-010398-5wot7tix 44 17 of of IN cord-010398-5wot7tix 44 18 being be VBG cord-010398-5wot7tix 44 19 diagnosed diagnose VBN cord-010398-5wot7tix 44 20 is be VBZ cord-010398-5wot7tix 44 21 markedly markedly RB cord-010398-5wot7tix 44 22 different different JJ cord-010398-5wot7tix 44 23 in in IN cord-010398-5wot7tix 44 24 different different JJ cord-010398-5wot7tix 44 25 settings setting NNS cord-010398-5wot7tix 44 26 [ [ -LRB- cord-010398-5wot7tix 44 27 20 20 CD cord-010398-5wot7tix 44 28 , , , cord-010398-5wot7tix 44 29 23 23 CD cord-010398-5wot7tix 44 30 ] ] -RRB- cord-010398-5wot7tix 44 31 . . . cord-010398-5wot7tix 45 1 Early early JJ cord-010398-5wot7tix 45 2 reports report NNS cord-010398-5wot7tix 45 3 from from IN cord-010398-5wot7tix 45 4 tertiary tertiary JJ cord-010398-5wot7tix 45 5 clinics clinic NNS cord-010398-5wot7tix 45 6 suggested suggest VBD cord-010398-5wot7tix 45 7 that that IN cord-010398-5wot7tix 45 8 CFS CFS NNP cord-010398-5wot7tix 45 9 affected affect VBD cord-010398-5wot7tix 45 10 primarily primarily RB cord-010398-5wot7tix 45 11 young young JJ cord-010398-5wot7tix 45 12 , , , cord-010398-5wot7tix 45 13 white white JJ cord-010398-5wot7tix 45 14 , , , cord-010398-5wot7tix 45 15 professionally professionally RB cord-010398-5wot7tix 45 16 successful successful JJ cord-010398-5wot7tix 45 17 women woman NNS cord-010398-5wot7tix 45 18 . . . cord-010398-5wot7tix 46 1 Women woman NNS cord-010398-5wot7tix 46 2 do do VBP cord-010398-5wot7tix 46 3 appear appear VB cord-010398-5wot7tix 46 4 to to TO cord-010398-5wot7tix 46 5 be be VB cord-010398-5wot7tix 46 6 1.5 1.5 CD cord-010398-5wot7tix 46 7 to to TO cord-010398-5wot7tix 46 8 2 2 CD cord-010398-5wot7tix 46 9 times time NNS cord-010398-5wot7tix 46 10 or or CC cord-010398-5wot7tix 46 11 more more RBR cord-010398-5wot7tix 46 12 likely likely JJ cord-010398-5wot7tix 46 13 to to TO cord-010398-5wot7tix 46 14 have have VB cord-010398-5wot7tix 46 15 CFS CFS NNP cord-010398-5wot7tix 46 16 in in IN cord-010398-5wot7tix 46 17 population population NN cord-010398-5wot7tix 46 18 - - HYPH cord-010398-5wot7tix 46 19 based base VBN cord-010398-5wot7tix 46 20 studies study NNS cord-010398-5wot7tix 46 21 , , , cord-010398-5wot7tix 46 22 but but CC cord-010398-5wot7tix 46 23 community community NN cord-010398-5wot7tix 46 24 surveys survey NNS cord-010398-5wot7tix 46 25 have have VBP cord-010398-5wot7tix 46 26 found find VBN cord-010398-5wot7tix 46 27 that that IN cord-010398-5wot7tix 46 28 white white JJ cord-010398-5wot7tix 46 29 men man NNS cord-010398-5wot7tix 46 30 and and CC cord-010398-5wot7tix 46 31 women woman NNS cord-010398-5wot7tix 46 32 have have VBP cord-010398-5wot7tix 46 33 a a DT cord-010398-5wot7tix 46 34 lower low JJR cord-010398-5wot7tix 46 35 risk risk NN cord-010398-5wot7tix 46 36 of of IN cord-010398-5wot7tix 46 37 CFS cfs NN cord-010398-5wot7tix 46 38 compared compare VBN cord-010398-5wot7tix 46 39 with with IN cord-010398-5wot7tix 46 40 Latino latino JJ cord-010398-5wot7tix 46 41 , , , cord-010398-5wot7tix 46 42 African african JJ cord-010398-5wot7tix 46 43 - - HYPH cord-010398-5wot7tix 46 44 American american JJ cord-010398-5wot7tix 46 45 , , , cord-010398-5wot7tix 46 46 and and CC cord-010398-5wot7tix 46 47 Native native JJ cord-010398-5wot7tix 46 48 American american JJ cord-010398-5wot7tix 46 49 subjects subject NNS cord-010398-5wot7tix 46 50 . . . cord-010398-5wot7tix 47 1 These these DT cord-010398-5wot7tix 47 2 disparate disparate JJ cord-010398-5wot7tix 47 3 findings finding NNS cord-010398-5wot7tix 47 4 suggest suggest VBP cord-010398-5wot7tix 47 5 that that IN cord-010398-5wot7tix 47 6 the the DT cord-010398-5wot7tix 47 7 increased increase VBN cord-010398-5wot7tix 47 8 prevalence prevalence NN cord-010398-5wot7tix 47 9 of of IN cord-010398-5wot7tix 47 10 CFS CFS NNP cord-010398-5wot7tix 47 11 among among IN cord-010398-5wot7tix 47 12 white white JJ cord-010398-5wot7tix 47 13 subjects subject NNS cord-010398-5wot7tix 47 14 in in IN cord-010398-5wot7tix 47 15 clinic clinic NN cord-010398-5wot7tix 47 16 populations population NNS cord-010398-5wot7tix 47 17 is be VBZ cord-010398-5wot7tix 47 18 most most RBS cord-010398-5wot7tix 47 19 likely likely JJ cord-010398-5wot7tix 47 20 the the DT cord-010398-5wot7tix 47 21 result result NN cord-010398-5wot7tix 47 22 of of IN cord-010398-5wot7tix 47 23 a a DT cord-010398-5wot7tix 47 24 disparity disparity NN cord-010398-5wot7tix 47 25 attributable attributable JJ cord-010398-5wot7tix 47 26 to to IN cord-010398-5wot7tix 47 27 health health NN cord-010398-5wot7tix 47 28 - - HYPH cord-010398-5wot7tix 47 29 care care NN cord-010398-5wot7tix 47 30 access access NN cord-010398-5wot7tix 47 31 and and CC cord-010398-5wot7tix 47 32 use use NN cord-010398-5wot7tix 47 33 . . . cord-010398-5wot7tix 48 1 functionally functionally RB cord-010398-5wot7tix 48 2 disabling disable VBG cord-010398-5wot7tix 48 3 . . . cord-010398-5wot7tix 49 1 The the DT cord-010398-5wot7tix 49 2 authors author NNS cord-010398-5wot7tix 49 3 of of IN cord-010398-5wot7tix 49 4 many many JJ cord-010398-5wot7tix 49 5 studies study NNS cord-010398-5wot7tix 49 6 report report VBP cord-010398-5wot7tix 49 7 that that IN cord-010398-5wot7tix 49 8 multidimensional multidimensional JJ cord-010398-5wot7tix 49 9 measures measure NNS cord-010398-5wot7tix 49 10 such such JJ cord-010398-5wot7tix 49 11 as as IN cord-010398-5wot7tix 49 12 the the DT cord-010398-5wot7tix 49 13 Multidimensional Multidimensional NNP cord-010398-5wot7tix 49 14 Fatigue Fatigue NNP cord-010398-5wot7tix 49 15 Inventory Inventory NNP cord-010398-5wot7tix 49 16 or or CC cord-010398-5wot7tix 49 17 Multidimensional Multidimensional NNP cord-010398-5wot7tix 49 18 Assessment Assessment NNP cord-010398-5wot7tix 49 19 of of IN cord-010398-5wot7tix 49 20 Fatigue Fatigue NNP cord-010398-5wot7tix 49 21 show show VBP cord-010398-5wot7tix 49 22 that that IN cord-010398-5wot7tix 49 23 patients patient NNS cord-010398-5wot7tix 49 24 with with IN cord-010398-5wot7tix 49 25 CFS cfs NN cord-010398-5wot7tix 49 26 experience experience NN cord-010398-5wot7tix 49 27 impairment impairment NN cord-010398-5wot7tix 49 28 in in IN cord-010398-5wot7tix 49 29 all all DT cord-010398-5wot7tix 49 30 fatigue fatigue NN cord-010398-5wot7tix 49 31 domains domain NNS cord-010398-5wot7tix 49 32 and and CC cord-010398-5wot7tix 49 33 that that IN cord-010398-5wot7tix 49 34 no no DT cord-010398-5wot7tix 49 35 single single JJ cord-010398-5wot7tix 49 36 domain domain NN cord-010398-5wot7tix 49 37 is be VBZ cord-010398-5wot7tix 49 38 any any DT cord-010398-5wot7tix 49 39 more more RBR cord-010398-5wot7tix 49 40 affected affected JJ cord-010398-5wot7tix 49 41 that that IN cord-010398-5wot7tix 49 42 any any DT cord-010398-5wot7tix 49 43 other other JJ cord-010398-5wot7tix 49 44 in in IN cord-010398-5wot7tix 49 45 a a DT cord-010398-5wot7tix 49 46 group group NN cord-010398-5wot7tix 49 47 of of IN cord-010398-5wot7tix 49 48 CFS cfs NN cord-010398-5wot7tix 49 49 patients patient NNS cord-010398-5wot7tix 49 50 [ [ -LRB- cord-010398-5wot7tix 49 51 24 24 CD cord-010398-5wot7tix 49 52 ] ] -RRB- cord-010398-5wot7tix 49 53 . . . cord-010398-5wot7tix 50 1 In in IN cord-010398-5wot7tix 50 2 general general JJ cord-010398-5wot7tix 50 3 , , , cord-010398-5wot7tix 50 4 although although IN cord-010398-5wot7tix 50 5 there there EX cord-010398-5wot7tix 50 6 are be VBP cord-010398-5wot7tix 50 7 individual individual JJ cord-010398-5wot7tix 50 8 studies study NNS cord-010398-5wot7tix 50 9 reporting report VBG cord-010398-5wot7tix 50 10 contrary contrary JJ cord-010398-5wot7tix 50 11 findings finding NNS cord-010398-5wot7tix 50 12 , , , cord-010398-5wot7tix 50 13 self self NN cord-010398-5wot7tix 50 14 - - HYPH cord-010398-5wot7tix 50 15 report report NN cord-010398-5wot7tix 50 16 measures measure NNS cord-010398-5wot7tix 50 17 of of IN cord-010398-5wot7tix 50 18 baseline baseline JJ cord-010398-5wot7tix 50 19 fatigue fatigue NN cord-010398-5wot7tix 50 20 ( ( -LRB- cord-010398-5wot7tix 50 21 measured measure VBN cord-010398-5wot7tix 50 22 in in IN cord-010398-5wot7tix 50 23 various various JJ cord-010398-5wot7tix 50 24 ways way NNS cord-010398-5wot7tix 50 25 ) ) -RRB- cord-010398-5wot7tix 50 26 correlate correlate VBP cord-010398-5wot7tix 50 27 poorly poorly RB cord-010398-5wot7tix 50 28 with with IN cord-010398-5wot7tix 50 29 objective objective JJ cord-010398-5wot7tix 50 30 measures measure NNS cord-010398-5wot7tix 50 31 of of IN cord-010398-5wot7tix 50 32 performance performance NN cord-010398-5wot7tix 50 33 ( ( -LRB- cord-010398-5wot7tix 50 34 eg eg UH cord-010398-5wot7tix 50 35 , , , cord-010398-5wot7tix 50 36 exercise exercise NN cord-010398-5wot7tix 50 37 or or CC cord-010398-5wot7tix 50 38 cognitive cognitive JJ cord-010398-5wot7tix 50 39 testing testing NN cord-010398-5wot7tix 50 40 ) ) -RRB- cord-010398-5wot7tix 50 41 , , , cord-010398-5wot7tix 50 42 leading lead VBG cord-010398-5wot7tix 50 43 many many JJ cord-010398-5wot7tix 50 44 authors author NNS cord-010398-5wot7tix 50 45 to to TO cord-010398-5wot7tix 50 46 emphasize emphasize VB cord-010398-5wot7tix 50 47 that that IN cord-010398-5wot7tix 50 48 " " `` cord-010398-5wot7tix 50 49 perception perception NN cord-010398-5wot7tix 50 50 " " '' cord-010398-5wot7tix 50 51 of of IN cord-010398-5wot7tix 50 52 fatigue fatigue NN cord-010398-5wot7tix 50 53 seems seem VBZ cord-010398-5wot7tix 50 54 to to TO cord-010398-5wot7tix 50 55 be be VB cord-010398-5wot7tix 50 56 abnormal abnormal JJ cord-010398-5wot7tix 50 57 in in IN cord-010398-5wot7tix 50 58 subjects subject NNS cord-010398-5wot7tix 50 59 with with IN cord-010398-5wot7tix 50 60 CFS CFS NNP cord-010398-5wot7tix 50 61 [ [ -LRB- cord-010398-5wot7tix 50 62 25 25 CD cord-010398-5wot7tix 50 63 ] ] -RRB- cord-010398-5wot7tix 50 64 [ [ -LRB- cord-010398-5wot7tix 50 65 26 26 CD cord-010398-5wot7tix 50 66 ] ] -RRB- cord-010398-5wot7tix 50 67 [ [ -LRB- cord-010398-5wot7tix 50 68 27 27 CD cord-010398-5wot7tix 50 69 ] ] -RRB- cord-010398-5wot7tix 50 70 [ [ -LRB- cord-010398-5wot7tix 50 71 28 28 CD cord-010398-5wot7tix 50 72 ] ] -RRB- cord-010398-5wot7tix 50 73 [ [ -LRB- cord-010398-5wot7tix 50 74 29 29 CD cord-010398-5wot7tix 50 75 ] ] -RRB- cord-010398-5wot7tix 50 76 . . . cord-010398-5wot7tix 51 1 The the DT cord-010398-5wot7tix 51 2 few few JJ cord-010398-5wot7tix 51 3 neurophysiologic neurophysiologic JJ cord-010398-5wot7tix 51 4 studies study NNS cord-010398-5wot7tix 51 5 performed perform VBN cord-010398-5wot7tix 51 6 likewise likewise RB cord-010398-5wot7tix 51 7 suggest suggest VBP cord-010398-5wot7tix 51 8 that that IN cord-010398-5wot7tix 51 9 there there EX cord-010398-5wot7tix 51 10 is be VBZ cord-010398-5wot7tix 51 11 diminished diminish VBN cord-010398-5wot7tix 51 12 central central JJ cord-010398-5wot7tix 51 13 activation activation NN cord-010398-5wot7tix 51 14 in in IN cord-010398-5wot7tix 51 15 patients patient NNS cord-010398-5wot7tix 51 16 with with IN cord-010398-5wot7tix 51 17 CFS CFS NNP cord-010398-5wot7tix 51 18 [ [ -LRB- cord-010398-5wot7tix 51 19 30 30 CD cord-010398-5wot7tix 51 20 , , , cord-010398-5wot7tix 51 21 31 31 CD cord-010398-5wot7tix 51 22 ] ] -RRB- cord-010398-5wot7tix 51 23 . . . cord-010398-5wot7tix 52 1 The the DT cord-010398-5wot7tix 52 2 best good JJS cord-010398-5wot7tix 52 3 indicator indicator NN cord-010398-5wot7tix 52 4 of of IN cord-010398-5wot7tix 52 5 whether whether IN cord-010398-5wot7tix 52 6 fatigue fatigue NN cord-010398-5wot7tix 52 7 is be VBZ cord-010398-5wot7tix 52 8 associated associate VBN cord-010398-5wot7tix 52 9 with with IN cord-010398-5wot7tix 52 10 CFS CFS NNP cord-010398-5wot7tix 52 11 rather rather RB cord-010398-5wot7tix 52 12 than than IN cord-010398-5wot7tix 52 13 another another DT cord-010398-5wot7tix 52 14 condition condition NN cord-010398-5wot7tix 52 15 is be VBZ cord-010398-5wot7tix 52 16 literally literally RB cord-010398-5wot7tix 52 17 in in IN cord-010398-5wot7tix 52 18 the the DT cord-010398-5wot7tix 52 19 company company NN cord-010398-5wot7tix 52 20 it -PRON- PRP cord-010398-5wot7tix 52 21 keeps keep VBZ cord-010398-5wot7tix 52 22 . . . cord-010398-5wot7tix 53 1 In in IN cord-010398-5wot7tix 53 2 the the DT cord-010398-5wot7tix 53 3 overwhelming overwhelming JJ cord-010398-5wot7tix 53 4 majority majority NN cord-010398-5wot7tix 53 5 of of IN cord-010398-5wot7tix 53 6 patients patient NNS cord-010398-5wot7tix 53 7 with with IN cord-010398-5wot7tix 53 8 CFS CFS NNP cord-010398-5wot7tix 53 9 , , , cord-010398-5wot7tix 53 10 the the DT cord-010398-5wot7tix 53 11 fatigue fatigue NN cord-010398-5wot7tix 53 12 is be VBZ cord-010398-5wot7tix 53 13 accompanied accompany VBN cord-010398-5wot7tix 53 14 by by IN cord-010398-5wot7tix 53 15 multifocal multifocal JJ cord-010398-5wot7tix 53 16 pain pain NN cord-010398-5wot7tix 53 17 , , , cord-010398-5wot7tix 53 18 sleep sleep NN cord-010398-5wot7tix 53 19 disturbances disturbance NNS cord-010398-5wot7tix 53 20 , , , cord-010398-5wot7tix 53 21 and/or and/or CC cord-010398-5wot7tix 53 22 cognitive cognitive JJ cord-010398-5wot7tix 53 23 difficulties difficulty NNS cord-010398-5wot7tix 53 24 . . . cord-010398-5wot7tix 54 1 These these DT cord-010398-5wot7tix 54 2 symptoms symptom NNS cord-010398-5wot7tix 54 3 are be VBP cord-010398-5wot7tix 54 4 encompassed encompass VBN cord-010398-5wot7tix 54 5 within within IN cord-010398-5wot7tix 54 6 the the DT cord-010398-5wot7tix 54 7 8 8 CD cord-010398-5wot7tix 54 8 " " `` cord-010398-5wot7tix 54 9 minor minor JJ cord-010398-5wot7tix 54 10 " " '' cord-010398-5wot7tix 54 11 criteria criterion NNS cord-010398-5wot7tix 54 12 for for IN cord-010398-5wot7tix 54 13 the the DT cord-010398-5wot7tix 54 14 CFS CFS NNP cord-010398-5wot7tix 54 15 diagnosis diagnosis NN cord-010398-5wot7tix 54 16 . . . cord-010398-5wot7tix 55 1 Many many JJ cord-010398-5wot7tix 55 2 patients patient NNS cord-010398-5wot7tix 55 3 with with IN cord-010398-5wot7tix 55 4 CFS CFS NNP cord-010398-5wot7tix 55 5 also also RB cord-010398-5wot7tix 55 6 experience experience NN cord-010398-5wot7tix 55 7 anorexia anorexia NN cord-010398-5wot7tix 55 8 , , , cord-010398-5wot7tix 55 9 nausea nausea NN cord-010398-5wot7tix 55 10 , , , cord-010398-5wot7tix 55 11 night night NN cord-010398-5wot7tix 55 12 sweats sweat NNS cord-010398-5wot7tix 55 13 , , , cord-010398-5wot7tix 55 14 a a DT cord-010398-5wot7tix 55 15 subjective subjective JJ cord-010398-5wot7tix 55 16 sense sense NN cord-010398-5wot7tix 55 17 of of IN cord-010398-5wot7tix 55 18 fevers fever NNS cord-010398-5wot7tix 55 19 , , , cord-010398-5wot7tix 55 20 frequent frequent JJ cord-010398-5wot7tix 55 21 dizziness dizziness NN cord-010398-5wot7tix 55 22 , , , cord-010398-5wot7tix 55 23 and and CC cord-010398-5wot7tix 55 24 intolerance intolerance NN cord-010398-5wot7tix 55 25 to to IN cord-010398-5wot7tix 55 26 alcohol alcohol NN cord-010398-5wot7tix 55 27 and and CC cord-010398-5wot7tix 55 28 medications medication NNS cord-010398-5wot7tix 55 29 . . . cord-010398-5wot7tix 56 1 Although although IN cord-010398-5wot7tix 56 2 the the DT cord-010398-5wot7tix 56 3 core core NN cord-010398-5wot7tix 56 4 symptom symptom NN cord-010398-5wot7tix 56 5 of of IN cord-010398-5wot7tix 56 6 CFS CFS NNP cord-010398-5wot7tix 56 7 is be VBZ cord-010398-5wot7tix 56 8 fatigue fatigue NN cord-010398-5wot7tix 56 9 , , , cord-010398-5wot7tix 56 10 the the DT cord-010398-5wot7tix 56 11 1994 1994 CD cord-010398-5wot7tix 56 12 CDC CDC NNP cord-010398-5wot7tix 56 13 criteria criterion NNS cord-010398-5wot7tix 56 14 for for IN cord-010398-5wot7tix 56 15 CFS CFS NNP cord-010398-5wot7tix 56 16 require require VBP cord-010398-5wot7tix 56 17 that that IN cord-010398-5wot7tix 56 18 a a DT cord-010398-5wot7tix 56 19 patient patient NN cord-010398-5wot7tix 56 20 experiences experience NNS cord-010398-5wot7tix 56 21 4 4 CD cord-010398-5wot7tix 56 22 or or CC cord-010398-5wot7tix 56 23 more more JJR cord-010398-5wot7tix 56 24 ( ( -LRB- cord-010398-5wot7tix 56 25 of of IN cord-010398-5wot7tix 56 26 a a DT cord-010398-5wot7tix 56 27 possible possible JJ cord-010398-5wot7tix 56 28 8) 8) NN cord-010398-5wot7tix 56 29 other other JJ cord-010398-5wot7tix 56 30 chronic chronic JJ cord-010398-5wot7tix 56 31 symptoms symptom NNS cord-010398-5wot7tix 56 32 besides besides IN cord-010398-5wot7tix 56 33 fatigue fatigue NN cord-010398-5wot7tix 56 34 to to TO cord-010398-5wot7tix 56 35 fulfill fulfill VB cord-010398-5wot7tix 56 36 these these DT cord-010398-5wot7tix 56 37 criteria criterion NNS cord-010398-5wot7tix 56 38 . . . cord-010398-5wot7tix 57 1 Five five CD cord-010398-5wot7tix 57 2 of of IN cord-010398-5wot7tix 57 3 the the DT cord-010398-5wot7tix 57 4 eight eight CD cord-010398-5wot7tix 57 5 symptoms symptom NNS cord-010398-5wot7tix 57 6 required require VBN cord-010398-5wot7tix 57 7 in in IN cord-010398-5wot7tix 57 8 addition addition NN cord-010398-5wot7tix 57 9 to to IN cord-010398-5wot7tix 57 10 fatigue fatigue NN cord-010398-5wot7tix 57 11 are be VBP cord-010398-5wot7tix 57 12 pain pain NN cord-010398-5wot7tix 57 13 - - HYPH cord-010398-5wot7tix 57 14 based base VBN cord-010398-5wot7tix 57 15 symptoms symptom NNS cord-010398-5wot7tix 57 16 ( ( -LRB- cord-010398-5wot7tix 57 17 sore sore JJ cord-010398-5wot7tix 57 18 throat throat NN cord-010398-5wot7tix 57 19 , , , cord-010398-5wot7tix 57 20 tender tender JJ cord-010398-5wot7tix 57 21 glands gland NNS cord-010398-5wot7tix 57 22 , , , cord-010398-5wot7tix 57 23 aching ache VBG cord-010398-5wot7tix 57 24 or or CC cord-010398-5wot7tix 57 25 stiff stiff JJ cord-010398-5wot7tix 57 26 muscles muscle NNS cord-010398-5wot7tix 57 27 , , , cord-010398-5wot7tix 57 28 multijoint multijoint NN cord-010398-5wot7tix 57 29 pain pain NN cord-010398-5wot7tix 57 30 , , , cord-010398-5wot7tix 57 31 new new JJ cord-010398-5wot7tix 57 32 headaches headache NNS cord-010398-5wot7tix 57 33 ) ) -RRB- cord-010398-5wot7tix 57 34 ; ; : cord-010398-5wot7tix 57 35 therefore therefore RB cord-010398-5wot7tix 57 36 , , , cord-010398-5wot7tix 57 37 it -PRON- PRP cord-010398-5wot7tix 57 38 is be VBZ cord-010398-5wot7tix 57 39 virtually virtually RB cord-010398-5wot7tix 57 40 impossible impossible JJ cord-010398-5wot7tix 57 41 for for IN cord-010398-5wot7tix 57 42 a a DT cord-010398-5wot7tix 57 43 patient patient NN cord-010398-5wot7tix 57 44 to to TO cord-010398-5wot7tix 57 45 meet meet VB cord-010398-5wot7tix 57 46 CDC CDC NNP cord-010398-5wot7tix 57 47 CFS CFS NNP cord-010398-5wot7tix 57 48 criteria criterion NNS cord-010398-5wot7tix 57 49 without without IN cord-010398-5wot7tix 57 50 having have VBG cord-010398-5wot7tix 57 51 pain pain NN cord-010398-5wot7tix 57 52 in in IN cord-010398-5wot7tix 57 53 at at RB cord-010398-5wot7tix 57 54 least least RBS cord-010398-5wot7tix 57 55 one one CD cord-010398-5wot7tix 57 56 body body NN cord-010398-5wot7tix 57 57 region region NN cord-010398-5wot7tix 57 58 . . . cord-010398-5wot7tix 58 1 In in IN cord-010398-5wot7tix 58 2 fact fact NN cord-010398-5wot7tix 58 3 , , , cord-010398-5wot7tix 58 4 most most JJS cord-010398-5wot7tix 58 5 patients patient NNS cord-010398-5wot7tix 58 6 with with IN cord-010398-5wot7tix 58 7 CFS CFS NNP cord-010398-5wot7tix 58 8 have have VBP cord-010398-5wot7tix 58 9 prominent prominent JJ cord-010398-5wot7tix 58 10 pain pain NN cord-010398-5wot7tix 58 11 in in IN cord-010398-5wot7tix 58 12 multiple multiple JJ cord-010398-5wot7tix 58 13 anatomical anatomical JJ cord-010398-5wot7tix 58 14 regions region NNS cord-010398-5wot7tix 58 15 , , , cord-010398-5wot7tix 58 16 especially especially RB cord-010398-5wot7tix 58 17 if if IN cord-010398-5wot7tix 58 18 they -PRON- PRP cord-010398-5wot7tix 58 19 are be VBP cord-010398-5wot7tix 58 20 queried query VBN cord-010398-5wot7tix 58 21 about about IN cord-010398-5wot7tix 58 22 chronic chronic JJ cord-010398-5wot7tix 58 23 pain pain NN cord-010398-5wot7tix 58 24 over over IN cord-010398-5wot7tix 58 25 the the DT cord-010398-5wot7tix 58 26 course course NN cord-010398-5wot7tix 58 27 of of IN cord-010398-5wot7tix 58 28 their -PRON- PRP$ cord-010398-5wot7tix 58 29 lifetime lifetime NN cord-010398-5wot7tix 58 30 . . . cord-010398-5wot7tix 59 1 In in IN cord-010398-5wot7tix 59 2 fact fact NN cord-010398-5wot7tix 59 3 , , , cord-010398-5wot7tix 59 4 an an DT cord-010398-5wot7tix 59 5 absence absence NN cord-010398-5wot7tix 59 6 of of IN cord-010398-5wot7tix 59 7 a a DT cord-010398-5wot7tix 59 8 history history NN cord-010398-5wot7tix 59 9 of of IN cord-010398-5wot7tix 59 10 multiple multiple JJ cord-010398-5wot7tix 59 11 sites site NNS cord-010398-5wot7tix 59 12 of of IN cord-010398-5wot7tix 59 13 pain pain NN cord-010398-5wot7tix 59 14 may may MD cord-010398-5wot7tix 59 15 differentiate differentiate VB cord-010398-5wot7tix 59 16 this this DT cord-010398-5wot7tix 59 17 particular particular JJ cord-010398-5wot7tix 59 18 subset subset NN cord-010398-5wot7tix 59 19 of of IN cord-010398-5wot7tix 59 20 CFS CFS NNP cord-010398-5wot7tix 59 21 patients patient NNS cord-010398-5wot7tix 59 22 from from IN cord-010398-5wot7tix 59 23 the the DT cord-010398-5wot7tix 59 24 subset subset NN cord-010398-5wot7tix 59 25 that that WDT cord-010398-5wot7tix 59 26 clearly clearly RB cord-010398-5wot7tix 59 27 overlaps overlap VBZ cord-010398-5wot7tix 59 28 with with IN cord-010398-5wot7tix 59 29 FM FM NNP cord-010398-5wot7tix 59 30 , , , cord-010398-5wot7tix 59 31 irritable irritable JJ cord-010398-5wot7tix 59 32 bowel bowel NN cord-010398-5wot7tix 59 33 syndrome syndrome NN cord-010398-5wot7tix 59 34 ( ( -LRB- cord-010398-5wot7tix 59 35 IBS IBS NNP cord-010398-5wot7tix 59 36 ) ) -RRB- cord-010398-5wot7tix 59 37 , , , cord-010398-5wot7tix 59 38 and and CC cord-010398-5wot7tix 59 39 chronic chronic JJ cord-010398-5wot7tix 59 40 headache headache NN cord-010398-5wot7tix 59 41 patients patient NNS cord-010398-5wot7tix 59 42 , , , cord-010398-5wot7tix 59 43 for for IN cord-010398-5wot7tix 59 44 example example NN cord-010398-5wot7tix 59 45 . . . cord-010398-5wot7tix 60 1 FM FM NNP cord-010398-5wot7tix 60 2 , , , cord-010398-5wot7tix 60 3 IBS IBS NNP cord-010398-5wot7tix 60 4 , , , cord-010398-5wot7tix 60 5 chronic chronic JJ cord-010398-5wot7tix 60 6 headaches headache NNS cord-010398-5wot7tix 60 7 , , , cord-010398-5wot7tix 60 8 and and CC cord-010398-5wot7tix 60 9 other other JJ cord-010398-5wot7tix 60 10 related related JJ cord-010398-5wot7tix 60 11 syndromes syndrome NNS cord-010398-5wot7tix 60 12 have have VBP cord-010398-5wot7tix 60 13 an an DT cord-010398-5wot7tix 60 14 interesting interesting JJ cord-010398-5wot7tix 60 15 history history NN cord-010398-5wot7tix 60 16 as as RB cord-010398-5wot7tix 60 17 well well RB cord-010398-5wot7tix 60 18 . . . cord-010398-5wot7tix 61 1 The the DT cord-010398-5wot7tix 61 2 terms term NNS cord-010398-5wot7tix 61 3 used use VBN cord-010398-5wot7tix 61 4 to to TO cord-010398-5wot7tix 61 5 describe describe VB cord-010398-5wot7tix 61 6 and and CC cord-010398-5wot7tix 61 7 label label VB cord-010398-5wot7tix 61 8 patients patient NNS cord-010398-5wot7tix 61 9 with with IN cord-010398-5wot7tix 61 10 these these DT cord-010398-5wot7tix 61 11 syndromes syndrome NNS cord-010398-5wot7tix 61 12 are be VBP cord-010398-5wot7tix 61 13 also also RB cord-010398-5wot7tix 61 14 largely largely RB cord-010398-5wot7tix 61 15 historical historical JJ cord-010398-5wot7tix 61 16 and and CC cord-010398-5wot7tix 61 17 at at IN cord-010398-5wot7tix 61 18 least least JJS cord-010398-5wot7tix 61 19 initially initially RB cord-010398-5wot7tix 61 20 were be VBD cord-010398-5wot7tix 61 21 viewed view VBN cord-010398-5wot7tix 61 22 through through IN cord-010398-5wot7tix 61 23 the the DT cord-010398-5wot7tix 61 24 perspective perspective NN cord-010398-5wot7tix 61 25 of of IN cord-010398-5wot7tix 61 26 the the DT cord-010398-5wot7tix 61 27 specialist specialist NN cord-010398-5wot7tix 61 28 that that WDT cord-010398-5wot7tix 61 29 sees see VBZ cord-010398-5wot7tix 61 30 patients patient NNS cord-010398-5wot7tix 61 31 with with IN cord-010398-5wot7tix 61 32 symptoms symptom NNS cord-010398-5wot7tix 61 33 in in IN cord-010398-5wot7tix 61 34 a a DT cord-010398-5wot7tix 61 35 particular particular JJ cord-010398-5wot7tix 61 36 region region NN cord-010398-5wot7tix 61 37 of of IN cord-010398-5wot7tix 61 38 the the DT cord-010398-5wot7tix 61 39 body body NN cord-010398-5wot7tix 61 40 or or CC cord-010398-5wot7tix 61 41 of of IN cord-010398-5wot7tix 61 42 underlying underlie VBG cord-010398-5wot7tix 61 43 pathogenesis pathogenesis NN cord-010398-5wot7tix 61 44 ( ( -LRB- cord-010398-5wot7tix 61 45 eg eg IN cord-010398-5wot7tix 61 46 , , , cord-010398-5wot7tix 61 47 infectious infectious JJ cord-010398-5wot7tix 61 48 disease disease NN cord-010398-5wot7tix 61 49 , , , cord-010398-5wot7tix 61 50 endocrinology endocrinology NN cord-010398-5wot7tix 61 51 ) ) -RRB- cord-010398-5wot7tix 61 52 . . . cord-010398-5wot7tix 62 1 Thus thus RB cord-010398-5wot7tix 62 2 , , , cord-010398-5wot7tix 62 3 an an DT cord-010398-5wot7tix 62 4 infectious infectious JJ cord-010398-5wot7tix 62 5 disease disease NN cord-010398-5wot7tix 62 6 expert expert NN cord-010398-5wot7tix 62 7 may may MD cord-010398-5wot7tix 62 8 see see VB cord-010398-5wot7tix 62 9 a a DT cord-010398-5wot7tix 62 10 patient patient NN cord-010398-5wot7tix 62 11 and and CC cord-010398-5wot7tix 62 12 focus focus VB cord-010398-5wot7tix 62 13 on on IN cord-010398-5wot7tix 62 14 the the DT cord-010398-5wot7tix 62 15 infectious infectious JJ cord-010398-5wot7tix 62 16 nature nature NN cord-010398-5wot7tix 62 17 of of IN cord-010398-5wot7tix 62 18 his -PRON- PRP$ cord-010398-5wot7tix 62 19 or or CC cord-010398-5wot7tix 62 20 her -PRON- PRP$ cord-010398-5wot7tix 62 21 symptoms symptom NNS cord-010398-5wot7tix 62 22 , , , cord-010398-5wot7tix 62 23 rule rule VB cord-010398-5wot7tix 62 24 out out RP cord-010398-5wot7tix 62 25 active active JJ cord-010398-5wot7tix 62 26 infection infection NN cord-010398-5wot7tix 62 27 , , , cord-010398-5wot7tix 62 28 and and CC cord-010398-5wot7tix 62 29 use use VB cord-010398-5wot7tix 62 30 the the DT cord-010398-5wot7tix 62 31 label label NN cord-010398-5wot7tix 62 32 CFS cfs NN cord-010398-5wot7tix 62 33 . . . cord-010398-5wot7tix 63 1 A a DT cord-010398-5wot7tix 63 2 physiatrist physiatrist NN cord-010398-5wot7tix 63 3 seeing see VBG cord-010398-5wot7tix 63 4 the the DT cord-010398-5wot7tix 63 5 same same JJ cord-010398-5wot7tix 63 6 patient patient NN cord-010398-5wot7tix 63 7 may may MD cord-010398-5wot7tix 63 8 focus focus VB cord-010398-5wot7tix 63 9 on on IN cord-010398-5wot7tix 63 10 the the DT cord-010398-5wot7tix 63 11 few few JJ cord-010398-5wot7tix 63 12 most most RBS cord-010398-5wot7tix 63 13 severe severe JJ cord-010398-5wot7tix 63 14 regions region NNS cord-010398-5wot7tix 63 15 of of IN cord-010398-5wot7tix 63 16 pain pain NN cord-010398-5wot7tix 63 17 and and CC cord-010398-5wot7tix 63 18 diagnose diagnose VB cord-010398-5wot7tix 63 19 myofascial myofascial JJ cord-010398-5wot7tix 63 20 pain pain NN cord-010398-5wot7tix 63 21 , , , cord-010398-5wot7tix 63 22 whereas whereas IN cord-010398-5wot7tix 63 23 a a DT cord-010398-5wot7tix 63 24 rheumatologist rheumatologist NN cord-010398-5wot7tix 63 25 instead instead RB cord-010398-5wot7tix 63 26 notes note VBZ cord-010398-5wot7tix 63 27 that that IN cord-010398-5wot7tix 63 28 the the DT cord-010398-5wot7tix 63 29 pain pain NN cord-010398-5wot7tix 63 30 is be VBZ cord-010398-5wot7tix 63 31 more more RBR cord-010398-5wot7tix 63 32 widespread widespread JJ cord-010398-5wot7tix 63 33 and and CC cord-010398-5wot7tix 63 34 not not RB cord-010398-5wot7tix 63 35 accompanied accompany VBN cord-010398-5wot7tix 63 36 by by IN cord-010398-5wot7tix 63 37 inflammation inflammation NN cord-010398-5wot7tix 63 38 and and CC cord-010398-5wot7tix 63 39 diagnoses diagnosis NNS cord-010398-5wot7tix 63 40 FM FM NNP cord-010398-5wot7tix 63 41 . . . cord-010398-5wot7tix 64 1 Historically historically RB cord-010398-5wot7tix 64 2 , , , cord-010398-5wot7tix 64 3 subspecialists subspecialist NNS cord-010398-5wot7tix 64 4 have have VBP cord-010398-5wot7tix 64 5 used use VBN cord-010398-5wot7tix 64 6 the the DT cord-010398-5wot7tix 64 7 descriptive descriptive JJ cord-010398-5wot7tix 64 8 terms term NNS cord-010398-5wot7tix 64 9 most most RBS cord-010398-5wot7tix 64 10 familiar familiar JJ cord-010398-5wot7tix 64 11 to to IN cord-010398-5wot7tix 64 12 them -PRON- PRP cord-010398-5wot7tix 64 13 given give VBN cord-010398-5wot7tix 64 14 their -PRON- PRP$ cord-010398-5wot7tix 64 15 training training NN cord-010398-5wot7tix 64 16 and and CC cord-010398-5wot7tix 64 17 patient patient JJ cord-010398-5wot7tix 64 18 populations population NNS cord-010398-5wot7tix 64 19 most most RBS cord-010398-5wot7tix 64 20 commonly commonly RB cord-010398-5wot7tix 64 21 treated treat VBN cord-010398-5wot7tix 64 22 . . . cord-010398-5wot7tix 65 1 When when WRB cord-010398-5wot7tix 65 2 researchers researcher NNS cord-010398-5wot7tix 65 3 question question VBP cord-010398-5wot7tix 65 4 the the DT cord-010398-5wot7tix 65 5 etiology etiology NN cord-010398-5wot7tix 65 6 of of IN cord-010398-5wot7tix 65 7 syndromes syndrome NNS cord-010398-5wot7tix 65 8 , , , cord-010398-5wot7tix 65 9 for for IN cord-010398-5wot7tix 65 10 example example NN cord-010398-5wot7tix 65 11 , , , cord-010398-5wot7tix 65 12 that that IN cord-010398-5wot7tix 65 13 EBV EBV NNP cord-010398-5wot7tix 65 14 does do VBZ cord-010398-5wot7tix 65 15 not not RB cord-010398-5wot7tix 65 16 cause cause VB cord-010398-5wot7tix 65 17 CFS CFS NNP cord-010398-5wot7tix 65 18 or or CC cord-010398-5wot7tix 65 19 autoimmune autoimmune JJ cord-010398-5wot7tix 65 20 dysfunction dysfunction NN cord-010398-5wot7tix 65 21 does do VBZ cord-010398-5wot7tix 65 22 not not RB cord-010398-5wot7tix 65 23 cause cause VB cord-010398-5wot7tix 65 24 FM FM NNP cord-010398-5wot7tix 65 25 , , , cord-010398-5wot7tix 65 26 the the DT cord-010398-5wot7tix 65 27 syndromes syndrome NNS cord-010398-5wot7tix 65 28 often often RB cord-010398-5wot7tix 65 29 are be VBP cord-010398-5wot7tix 65 30 renamed rename VBN cord-010398-5wot7tix 65 31 . . . cord-010398-5wot7tix 66 1 " " '' cord-010398-5wot7tix 67 1 Chronic chronic JJ cord-010398-5wot7tix 67 2 EBV EBV NNP cord-010398-5wot7tix 67 3 syndrome syndrome NN cord-010398-5wot7tix 67 4 " " '' cord-010398-5wot7tix 67 5 became become VBD cord-010398-5wot7tix 67 6 CFS cfs NN cord-010398-5wot7tix 67 7 when when WRB cord-010398-5wot7tix 67 8 EBV EBV NNP cord-010398-5wot7tix 67 9 was be VBD cord-010398-5wot7tix 67 10 shown show VBN cord-010398-5wot7tix 67 11 to to TO cord-010398-5wot7tix 67 12 not not RB cord-010398-5wot7tix 67 13 be be VB cord-010398-5wot7tix 67 14 the the DT cord-010398-5wot7tix 67 15 causative causative JJ cord-010398-5wot7tix 67 16 agent agent NN cord-010398-5wot7tix 67 17 . . . cord-010398-5wot7tix 68 1 Fibrositis Fibrositis NNP cord-010398-5wot7tix 68 2 became become VBD cord-010398-5wot7tix 68 3 FM FM NNP cord-010398-5wot7tix 68 4 when when WRB cord-010398-5wot7tix 68 5 it -PRON- PRP cord-010398-5wot7tix 68 6 was be VBD cord-010398-5wot7tix 68 7 clear clear JJ cord-010398-5wot7tix 68 8 there there EX cord-010398-5wot7tix 68 9 was be VBD cord-010398-5wot7tix 68 10 no no DT cord-010398-5wot7tix 68 11 diffuse diffuse JJ cord-010398-5wot7tix 68 12 inflammation inflammation NN cord-010398-5wot7tix 68 13 of of IN cord-010398-5wot7tix 68 14 fibrous fibrous JJ cord-010398-5wot7tix 68 15 tissue tissue NN cord-010398-5wot7tix 68 16 throughout throughout IN cord-010398-5wot7tix 68 17 the the DT cord-010398-5wot7tix 68 18 body body NN cord-010398-5wot7tix 69 1 and and CC cord-010398-5wot7tix 69 2 it -PRON- PRP cord-010398-5wot7tix 69 3 was be VBD cord-010398-5wot7tix 69 4 demonstrated demonstrate VBN cord-010398-5wot7tix 69 5 instead instead RB cord-010398-5wot7tix 69 6 to to TO cord-010398-5wot7tix 69 7 be be VB cord-010398-5wot7tix 69 8 a a DT cord-010398-5wot7tix 69 9 result result NN cord-010398-5wot7tix 69 10 of of IN cord-010398-5wot7tix 69 11 central central JJ cord-010398-5wot7tix 69 12 pain pain NN cord-010398-5wot7tix 69 13 augmentation augmentation NN cord-010398-5wot7tix 69 14 characterized characterize VBN cord-010398-5wot7tix 69 15 by by IN cord-010398-5wot7tix 69 16 widespread widespread JJ cord-010398-5wot7tix 69 17 pain pain NN cord-010398-5wot7tix 69 18 . . . cord-010398-5wot7tix 70 1 Spastic spastic JJ cord-010398-5wot7tix 70 2 colitis colitis NN cord-010398-5wot7tix 70 3 similarly similarly RB cord-010398-5wot7tix 70 4 became become VBD cord-010398-5wot7tix 70 5 IBS IBS NNP cord-010398-5wot7tix 70 6 , , , cord-010398-5wot7tix 70 7 temporomandibular temporomandibular NN cord-010398-5wot7tix 70 8 joint joint NN cord-010398-5wot7tix 70 9 ( ( -LRB- cord-010398-5wot7tix 70 10 TMJ TMJ NNP cord-010398-5wot7tix 70 11 ) ) -RRB- cord-010398-5wot7tix 70 12 syndrome syndrome NN cord-010398-5wot7tix 70 13 became become VBD cord-010398-5wot7tix 70 14 temporomandibular temporomandibular NN cord-010398-5wot7tix 70 15 joint joint JJ cord-010398-5wot7tix 70 16 disorder disorder NN cord-010398-5wot7tix 70 17 ( ( -LRB- cord-010398-5wot7tix 70 18 TMJD TMJD NNP cord-010398-5wot7tix 70 19 ) ) -RRB- cord-010398-5wot7tix 70 20 , , , cord-010398-5wot7tix 70 21 and and CC cord-010398-5wot7tix 70 22 interstitial interstitial JJ cord-010398-5wot7tix 70 23 cystitis cystitis NN cord-010398-5wot7tix 70 24 is be VBZ cord-010398-5wot7tix 70 25 well well RB cord-010398-5wot7tix 70 26 on on IN cord-010398-5wot7tix 70 27 its -PRON- PRP$ cord-010398-5wot7tix 70 28 way way NN cord-010398-5wot7tix 70 29 to to TO cord-010398-5wot7tix 70 30 be be VB cord-010398-5wot7tix 70 31 renamed rename VBN cord-010398-5wot7tix 70 32 painful painful JJ cord-010398-5wot7tix 70 33 bladder bladder NN cord-010398-5wot7tix 70 34 syndrome syndrome NN cord-010398-5wot7tix 70 35 , , , cord-010398-5wot7tix 70 36 all all RB cord-010398-5wot7tix 70 37 because because IN cord-010398-5wot7tix 70 38 of of IN cord-010398-5wot7tix 70 39 the the DT cord-010398-5wot7tix 70 40 recognition recognition NN cord-010398-5wot7tix 70 41 that that IN cord-010398-5wot7tix 70 42 central central JJ cord-010398-5wot7tix 70 43 factors factor NNS cord-010398-5wot7tix 70 44 rather rather RB cord-010398-5wot7tix 70 45 than than IN cord-010398-5wot7tix 70 46 peripheral peripheral JJ cord-010398-5wot7tix 70 47 damage damage NN cord-010398-5wot7tix 70 48 or or CC cord-010398-5wot7tix 70 49 inflammation inflammation NN cord-010398-5wot7tix 70 50 appear appear VBP cord-010398-5wot7tix 70 51 to to TO cord-010398-5wot7tix 70 52 be be VB cord-010398-5wot7tix 70 53 driving drive VBG cord-010398-5wot7tix 70 54 the the DT cord-010398-5wot7tix 70 55 pain pain NN cord-010398-5wot7tix 70 56 . . . cord-010398-5wot7tix 71 1 Even even RB cord-010398-5wot7tix 71 2 psychiatrists psychiatrist NNS cord-010398-5wot7tix 71 3 got get VBD cord-010398-5wot7tix 71 4 into into IN cord-010398-5wot7tix 71 5 the the DT cord-010398-5wot7tix 71 6 misnaming misnaming NN cord-010398-5wot7tix 71 7 game game NN cord-010398-5wot7tix 71 8 . . . cord-010398-5wot7tix 72 1 The the DT cord-010398-5wot7tix 72 2 terms term NNS cord-010398-5wot7tix 72 3 somatoform somatoform NN cord-010398-5wot7tix 72 4 disorder disorder NN cord-010398-5wot7tix 72 5 and and CC cord-010398-5wot7tix 72 6 somatization somatization NN cord-010398-5wot7tix 72 7 imply imply VBP cord-010398-5wot7tix 72 8 that that IN cord-010398-5wot7tix 72 9 patients patient NNS cord-010398-5wot7tix 72 10 have have VBP cord-010398-5wot7tix 72 11 multiple multiple JJ cord-010398-5wot7tix 72 12 somatic somatic JJ cord-010398-5wot7tix 72 13 symptoms symptom NNS cord-010398-5wot7tix 72 14 over over IN cord-010398-5wot7tix 72 15 the the DT cord-010398-5wot7tix 72 16 course course NN cord-010398-5wot7tix 72 17 of of IN cord-010398-5wot7tix 72 18 their -PRON- PRP$ cord-010398-5wot7tix 72 19 lifetime lifetime NN cord-010398-5wot7tix 72 20 without without IN cord-010398-5wot7tix 72 21 any any DT cord-010398-5wot7tix 72 22 clear clear JJ cord-010398-5wot7tix 72 23 " " `` cord-010398-5wot7tix 72 24 organic organic JJ cord-010398-5wot7tix 72 25 " " '' cord-010398-5wot7tix 72 26 cause cause NN cord-010398-5wot7tix 72 27 . . . cord-010398-5wot7tix 73 1 This this DT cord-010398-5wot7tix 73 2 term term NN cord-010398-5wot7tix 73 3 also also RB cord-010398-5wot7tix 73 4 is be VBZ cord-010398-5wot7tix 73 5 rapidly rapidly RB cord-010398-5wot7tix 73 6 losing lose VBG cord-010398-5wot7tix 73 7 credibility credibility NN cord-010398-5wot7tix 73 8 as as IN cord-010398-5wot7tix 73 9 it -PRON- PRP cord-010398-5wot7tix 73 10 becomes become VBZ cord-010398-5wot7tix 73 11 increasingly increasingly RB cord-010398-5wot7tix 73 12 clear clear JJ cord-010398-5wot7tix 73 13 that that IN cord-010398-5wot7tix 73 14 there there EX cord-010398-5wot7tix 73 15 are be VBP cord-010398-5wot7tix 73 16 in in IN cord-010398-5wot7tix 73 17 fact fact NN cord-010398-5wot7tix 73 18 objective objective JJ cord-010398-5wot7tix 73 19 neurobiological neurobiological JJ cord-010398-5wot7tix 73 20 underpinnings underpinning NNS cord-010398-5wot7tix 73 21 to to IN cord-010398-5wot7tix 73 22 this this DT cord-010398-5wot7tix 73 23 spectrum spectrum NN cord-010398-5wot7tix 73 24 of of IN cord-010398-5wot7tix 73 25 illness illness NN cord-010398-5wot7tix 73 26 . . . cord-010398-5wot7tix 74 1 There there EX cord-010398-5wot7tix 74 2 is be VBZ cord-010398-5wot7tix 74 3 now now RB cord-010398-5wot7tix 74 4 unanimity unanimity NN cord-010398-5wot7tix 74 5 that that IN cord-010398-5wot7tix 74 6 at at IN cord-010398-5wot7tix 74 7 least least JJS cord-010398-5wot7tix 74 8 a a DT cord-010398-5wot7tix 74 9 large large JJ cord-010398-5wot7tix 74 10 subset subset NN cord-010398-5wot7tix 74 11 of of IN cord-010398-5wot7tix 74 12 patients patient NNS cord-010398-5wot7tix 74 13 with with IN cord-010398-5wot7tix 74 14 CFS CFS NNP cord-010398-5wot7tix 74 15 have have VBP cord-010398-5wot7tix 74 16 a a DT cord-010398-5wot7tix 74 17 condition condition NN cord-010398-5wot7tix 74 18 that that WDT cord-010398-5wot7tix 74 19 is be VBZ cord-010398-5wot7tix 74 20 much much RB cord-010398-5wot7tix 74 21 broader broad JJR cord-010398-5wot7tix 74 22 than than IN cord-010398-5wot7tix 74 23 just just RB cord-010398-5wot7tix 74 24 CFS CFS NNP cord-010398-5wot7tix 74 25 and and CC cord-010398-5wot7tix 74 26 has have VBZ cord-010398-5wot7tix 74 27 been be VBN cord-010398-5wot7tix 74 28 labeled label VBN cord-010398-5wot7tix 74 29 variously variously RB cord-010398-5wot7tix 74 30 , , , cord-010398-5wot7tix 74 31 including include VBG cord-010398-5wot7tix 74 32 " " `` cord-010398-5wot7tix 74 33 functional functional JJ cord-010398-5wot7tix 74 34 somatic somatic JJ cord-010398-5wot7tix 74 35 syndromes syndrome NNS cord-010398-5wot7tix 74 36 , , , cord-010398-5wot7tix 74 37 " " '' cord-010398-5wot7tix 74 38 " " `` cord-010398-5wot7tix 74 39 medically medically RB cord-010398-5wot7tix 74 40 unexplained unexplained JJ cord-010398-5wot7tix 74 41 symptoms symptom NNS cord-010398-5wot7tix 74 42 , , , cord-010398-5wot7tix 74 43 " " '' cord-010398-5wot7tix 74 44 " " `` cord-010398-5wot7tix 74 45 chronic chronic JJ cord-010398-5wot7tix 74 46 multisymptom multisymptom JJ cord-010398-5wot7tix 74 47 illnesses illness NNS cord-010398-5wot7tix 74 48 , , , cord-010398-5wot7tix 74 49 " " '' cord-010398-5wot7tix 74 50 " " `` cord-010398-5wot7tix 74 51 somatoform somatoform JJ cord-010398-5wot7tix 74 52 disorders disorder NNS cord-010398-5wot7tix 74 53 , , , cord-010398-5wot7tix 74 54 " " '' cord-010398-5wot7tix 74 55 and and CC cord-010398-5wot7tix 74 56 perhaps perhaps RB cord-010398-5wot7tix 74 57 most most RBS cord-010398-5wot7tix 74 58 appropriately appropriately RB cord-010398-5wot7tix 74 59 , , , cord-010398-5wot7tix 74 60 " " `` cord-010398-5wot7tix 74 61 central central JJ cord-010398-5wot7tix 74 62 sensitivity sensitivity NN cord-010398-5wot7tix 74 63 syndromes syndrome NNS cord-010398-5wot7tix 74 64 . . . cord-010398-5wot7tix 74 65 " " '' cord-010398-5wot7tix 75 1 Yunus Yunus NNP cord-010398-5wot7tix 75 2 [ [ -LRB- cord-010398-5wot7tix 75 3 32 32 CD cord-010398-5wot7tix 75 4 ] ] -RRB- cord-010398-5wot7tix 75 5 first first RB cord-010398-5wot7tix 75 6 showed show VBD cord-010398-5wot7tix 75 7 FM FM NNP cord-010398-5wot7tix 75 8 to to TO cord-010398-5wot7tix 75 9 be be VB cord-010398-5wot7tix 75 10 associated associate VBN cord-010398-5wot7tix 75 11 with with IN cord-010398-5wot7tix 75 12 tension tension NN cord-010398-5wot7tix 75 13 - - HYPH cord-010398-5wot7tix 75 14 type type NN cord-010398-5wot7tix 75 15 headache headache NN cord-010398-5wot7tix 75 16 , , , cord-010398-5wot7tix 75 17 migraine migraine NN cord-010398-5wot7tix 75 18 , , , cord-010398-5wot7tix 75 19 and and CC cord-010398-5wot7tix 75 20 IBS IBS NNP cord-010398-5wot7tix 75 21 ; ; : cord-010398-5wot7tix 75 22 this this DT cord-010398-5wot7tix 75 23 author author NN cord-010398-5wot7tix 75 24 designed design VBD cord-010398-5wot7tix 75 25 a a DT cord-010398-5wot7tix 75 26 Venn Venn NNP cord-010398-5wot7tix 75 27 diagram diagram NN cord-010398-5wot7tix 75 28 in in IN cord-010398-5wot7tix 75 29 1984 1984 CD cord-010398-5wot7tix 75 30 that that WDT cord-010398-5wot7tix 75 31 emphasized emphasize VBD cord-010398-5wot7tix 75 32 the the DT cord-010398-5wot7tix 75 33 epidemiological epidemiological JJ cord-010398-5wot7tix 75 34 and and CC cord-010398-5wot7tix 75 35 clinical clinical JJ cord-010398-5wot7tix 75 36 overlaps overlap NNS cord-010398-5wot7tix 75 37 between between IN cord-010398-5wot7tix 75 38 these these DT cord-010398-5wot7tix 75 39 syndromes syndrome NNS cord-010398-5wot7tix 75 40 and and CC cord-010398-5wot7tix 75 41 primary primary JJ cord-010398-5wot7tix 75 42 dysmenorrhea dysmenorrhea NN cord-010398-5wot7tix 75 43 . . . cord-010398-5wot7tix 76 1 This this DT cord-010398-5wot7tix 76 2 diagram diagram NN cord-010398-5wot7tix 76 3 helped help VBD cord-010398-5wot7tix 76 4 stimulate stimulate VB cord-010398-5wot7tix 76 5 research research NN cord-010398-5wot7tix 76 6 to to TO cord-010398-5wot7tix 76 7 search search VB cord-010398-5wot7tix 76 8 for for IN cord-010398-5wot7tix 76 9 etiological etiological JJ cord-010398-5wot7tix 76 10 connections connection NNS cord-010398-5wot7tix 76 11 among among IN cord-010398-5wot7tix 76 12 these these DT cord-010398-5wot7tix 76 13 syndromes syndrome NNS cord-010398-5wot7tix 76 14 [ [ -LRB- cord-010398-5wot7tix 76 15 32 32 CD cord-010398-5wot7tix 76 16 , , , cord-010398-5wot7tix 76 17 33 33 CD cord-010398-5wot7tix 76 18 ] ] -RRB- cord-010398-5wot7tix 76 19 . . . cord-010398-5wot7tix 77 1 Hudson Hudson NNP cord-010398-5wot7tix 77 2 and and CC cord-010398-5wot7tix 77 3 colleagues colleague NNS cord-010398-5wot7tix 77 4 [ [ -LRB- cord-010398-5wot7tix 77 5 34 34 CD cord-010398-5wot7tix 77 6 ] ] -RRB- cord-010398-5wot7tix 77 7 [ [ -LRB- cord-010398-5wot7tix 77 8 35 35 CD cord-010398-5wot7tix 77 9 ] ] -RRB- cord-010398-5wot7tix 77 10 [ [ -LRB- cord-010398-5wot7tix 77 11 36 36 CD cord-010398-5wot7tix 77 12 ] ] -RRB- cord-010398-5wot7tix 77 13 demonstrated demonstrate VBD cord-010398-5wot7tix 77 14 that that IN cord-010398-5wot7tix 77 15 conditions condition NNS cord-010398-5wot7tix 77 16 such such JJ cord-010398-5wot7tix 77 17 as as IN cord-010398-5wot7tix 77 18 CFS CFS NNP cord-010398-5wot7tix 77 19 , , , cord-010398-5wot7tix 77 20 FM FM NNP cord-010398-5wot7tix 77 21 , , , cord-010398-5wot7tix 77 22 IBS IBS NNP cord-010398-5wot7tix 77 23 , , , cord-010398-5wot7tix 77 24 and and CC cord-010398-5wot7tix 77 25 other other JJ cord-010398-5wot7tix 77 26 pain pain NN cord-010398-5wot7tix 77 27 / / SYM cord-010398-5wot7tix 77 28 fatigue fatigue NN cord-010398-5wot7tix 77 29 syndromes syndrome NNS cord-010398-5wot7tix 77 30 coaggregated coaggregate VBN cord-010398-5wot7tix 77 31 in in IN cord-010398-5wot7tix 77 32 patients patient NNS cord-010398-5wot7tix 77 33 and and CC cord-010398-5wot7tix 77 34 in in IN cord-010398-5wot7tix 77 35 families family NNS cord-010398-5wot7tix 77 36 . . . cord-010398-5wot7tix 78 1 In in IN cord-010398-5wot7tix 78 2 this this DT cord-010398-5wot7tix 78 3 review review NN cord-010398-5wot7tix 78 4 , , , cord-010398-5wot7tix 78 5 the the DT cord-010398-5wot7tix 78 6 more more RBR cord-010398-5wot7tix 78 7 recent recent JJ cord-010398-5wot7tix 78 8 term term NN cord-010398-5wot7tix 78 9 central central JJ cord-010398-5wot7tix 78 10 sensitivity sensitivity NN cord-010398-5wot7tix 78 11 syndrome syndrome NN cord-010398-5wot7tix 78 12 ( ( -LRB- cord-010398-5wot7tix 78 13 CSS CSS NNP cord-010398-5wot7tix 78 14 ) ) -RRB- cord-010398-5wot7tix 78 15 as as IN cord-010398-5wot7tix 78 16 proposed propose VBN cord-010398-5wot7tix 78 17 by by IN cord-010398-5wot7tix 78 18 Yunus Yunus NNP cord-010398-5wot7tix 78 19 is be VBZ cord-010398-5wot7tix 78 20 used use VBN cord-010398-5wot7tix 78 21 because because IN cord-010398-5wot7tix 78 22 , , , cord-010398-5wot7tix 78 23 in in IN cord-010398-5wot7tix 78 24 the the DT cord-010398-5wot7tix 78 25 opinion opinion NN cord-010398-5wot7tix 78 26 of of IN cord-010398-5wot7tix 78 27 the the DT cord-010398-5wot7tix 78 28 review review NN cord-010398-5wot7tix 78 29 author author NN cord-010398-5wot7tix 78 30 , , , cord-010398-5wot7tix 78 31 it -PRON- PRP cord-010398-5wot7tix 78 32 represents represent VBZ cord-010398-5wot7tix 78 33 the the DT cord-010398-5wot7tix 78 34 best good JJS cord-010398-5wot7tix 78 35 nosological nosological JJ cord-010398-5wot7tix 78 36 term term NN cord-010398-5wot7tix 78 37 at at IN cord-010398-5wot7tix 78 38 present present NN cord-010398-5wot7tix 78 39 . . . cord-010398-5wot7tix 79 1 There there EX cord-010398-5wot7tix 79 2 is be VBZ cord-010398-5wot7tix 79 3 also also RB cord-010398-5wot7tix 79 4 a a DT cord-010398-5wot7tix 79 5 clear clear JJ cord-010398-5wot7tix 79 6 overlap overlap NN cord-010398-5wot7tix 79 7 between between IN cord-010398-5wot7tix 79 8 the the DT cord-010398-5wot7tix 79 9 CSS css NN cord-010398-5wot7tix 79 10 disorders disorder NNS cord-010398-5wot7tix 79 11 and and CC cord-010398-5wot7tix 79 12 a a DT cord-010398-5wot7tix 79 13 variety variety NN cord-010398-5wot7tix 79 14 of of IN cord-010398-5wot7tix 79 15 psychiatric psychiatric JJ cord-010398-5wot7tix 79 16 disorders disorder NNS cord-010398-5wot7tix 79 17 ( ( -LRB- cord-010398-5wot7tix 79 18 Table table NN cord-010398-5wot7tix 79 19 1 1 CD cord-010398-5wot7tix 79 20 ) ) -RRB- cord-010398-5wot7tix 79 21 . . . cord-010398-5wot7tix 80 1 This this DT cord-010398-5wot7tix 80 2 overlap overlap VBP cord-010398-5wot7tix 80 3 likely likely RB cord-010398-5wot7tix 80 4 occurs occur VBZ cord-010398-5wot7tix 80 5 at at IN cord-010398-5wot7tix 80 6 least least JJS cord-010398-5wot7tix 80 7 in in IN cord-010398-5wot7tix 80 8 part part NN cord-010398-5wot7tix 80 9 because because IN cord-010398-5wot7tix 80 10 the the DT cord-010398-5wot7tix 80 11 same same JJ cord-010398-5wot7tix 80 12 neurotransmitters neurotransmitter NNS cord-010398-5wot7tix 80 13 ( ( -LRB- cord-010398-5wot7tix 80 14 albeit albeit IN cord-010398-5wot7tix 80 15 in in IN cord-010398-5wot7tix 80 16 different different JJ cord-010398-5wot7tix 80 17 brain brain NN cord-010398-5wot7tix 80 18 regions region NNS cord-010398-5wot7tix 80 19 ) ) -RRB- cord-010398-5wot7tix 80 20 are be VBP cord-010398-5wot7tix 80 21 operative operative JJ cord-010398-5wot7tix 80 22 in in IN cord-010398-5wot7tix 80 23 psychiatric psychiatric JJ cord-010398-5wot7tix 80 24 conditions condition NNS cord-010398-5wot7tix 80 25 . . . cord-010398-5wot7tix 81 1 The the DT cord-010398-5wot7tix 81 2 presence presence NN cord-010398-5wot7tix 81 3 of of IN cord-010398-5wot7tix 81 4 comorbid comorbid JJ cord-010398-5wot7tix 81 5 psychiatric psychiatric JJ cord-010398-5wot7tix 81 6 disturbances disturbance NNS cord-010398-5wot7tix 81 7 is be VBZ cord-010398-5wot7tix 81 8 somewhat somewhat RB cord-010398-5wot7tix 81 9 more more RBR cord-010398-5wot7tix 81 10 common common JJ cord-010398-5wot7tix 81 11 in in IN cord-010398-5wot7tix 81 12 patients patient NNS cord-010398-5wot7tix 81 13 with with IN cord-010398-5wot7tix 81 14 CSS css NN cord-010398-5wot7tix 81 15 seen see VBN cord-010398-5wot7tix 81 16 in in IN cord-010398-5wot7tix 81 17 tertiary tertiary JJ cord-010398-5wot7tix 81 18 care care NN cord-010398-5wot7tix 81 19 settings setting NNS cord-010398-5wot7tix 81 20 than than IN cord-010398-5wot7tix 81 21 primary primary JJ cord-010398-5wot7tix 81 22 care care NN cord-010398-5wot7tix 81 23 settings setting NNS cord-010398-5wot7tix 81 24 [ [ -LRB- cord-010398-5wot7tix 81 25 37 37 CD cord-010398-5wot7tix 81 26 , , , cord-010398-5wot7tix 81 27 38 38 CD cord-010398-5wot7tix 81 28 ] ] -RRB- cord-010398-5wot7tix 81 29 . . . cord-010398-5wot7tix 82 1 Figure figure NN cord-010398-5wot7tix 82 2 1 1 CD cord-010398-5wot7tix 82 3 demonstrates demonstrate VBZ cord-010398-5wot7tix 82 4 the the DT cord-010398-5wot7tix 82 5 overlap overlap NN cord-010398-5wot7tix 82 6 among among IN cord-010398-5wot7tix 82 7 FM FM NNP cord-010398-5wot7tix 82 8 , , , cord-010398-5wot7tix 82 9 CFS CFS NNP cord-010398-5wot7tix 82 10 , , , cord-010398-5wot7tix 82 11 and and CC cord-010398-5wot7tix 82 12 a a DT cord-010398-5wot7tix 82 13 variety variety NN cord-010398-5wot7tix 82 14 of of IN cord-010398-5wot7tix 82 15 regional regional JJ cord-010398-5wot7tix 82 16 pain pain NN cord-010398-5wot7tix 82 17 syndromes syndrome NNS cord-010398-5wot7tix 82 18 as as RB cord-010398-5wot7tix 82 19 well well RB cord-010398-5wot7tix 82 20 as as IN cord-010398-5wot7tix 82 21 psychiatric psychiatric JJ cord-010398-5wot7tix 82 22 disorders disorder NNS cord-010398-5wot7tix 82 23 and and CC cord-010398-5wot7tix 82 24 demonstrates demonstrate VBZ cord-010398-5wot7tix 82 25 that that IN cord-010398-5wot7tix 82 26 the the DT cord-010398-5wot7tix 82 27 common common JJ cord-010398-5wot7tix 82 28 underlying underlying JJ cord-010398-5wot7tix 82 29 pathophysiological pathophysiological JJ cord-010398-5wot7tix 82 30 mechanism mechanism NN cord-010398-5wot7tix 82 31 observed observe VBN cord-010398-5wot7tix 82 32 in in IN cord-010398-5wot7tix 82 33 most most JJS cord-010398-5wot7tix 82 34 patients patient NNS cord-010398-5wot7tix 82 35 with with IN cord-010398-5wot7tix 82 36 FM FM NNP cord-010398-5wot7tix 82 37 , , , cord-010398-5wot7tix 82 38 and and CC cord-010398-5wot7tix 82 39 large large JJ cord-010398-5wot7tix 82 40 subsets subset NNS cord-010398-5wot7tix 82 41 of of IN cord-010398-5wot7tix 82 42 patients patient NNS cord-010398-5wot7tix 82 43 with with IN cord-010398-5wot7tix 82 44 these these DT cord-010398-5wot7tix 82 45 other other JJ cord-010398-5wot7tix 82 46 syndromes syndrome NNS cord-010398-5wot7tix 82 47 , , , cord-010398-5wot7tix 82 48 is be VBZ cord-010398-5wot7tix 82 49 central central JJ cord-010398-5wot7tix 82 50 nervous nervous JJ cord-010398-5wot7tix 82 51 system system NN cord-010398-5wot7tix 82 52 pain pain NN cord-010398-5wot7tix 82 53 or or CC cord-010398-5wot7tix 82 54 sensory sensory JJ cord-010398-5wot7tix 82 55 amplification amplification NN cord-010398-5wot7tix 82 56 . . . cord-010398-5wot7tix 83 1 The the DT cord-010398-5wot7tix 83 2 use use NN cord-010398-5wot7tix 83 3 of of IN cord-010398-5wot7tix 83 4 research research NN cord-010398-5wot7tix 83 5 methods method NNS cord-010398-5wot7tix 83 6 such such JJ cord-010398-5wot7tix 83 7 as as IN cord-010398-5wot7tix 83 8 epidemiological epidemiological JJ cord-010398-5wot7tix 83 9 and and CC cord-010398-5wot7tix 83 10 twin twin JJ cord-010398-5wot7tix 83 11 studies study NNS cord-010398-5wot7tix 83 12 , , , cord-010398-5wot7tix 83 13 experimental experimental JJ cord-010398-5wot7tix 83 14 pain pain NN cord-010398-5wot7tix 83 15 testing testing NN cord-010398-5wot7tix 83 16 , , , cord-010398-5wot7tix 83 17 functional functional JJ cord-010398-5wot7tix 83 18 imaging imaging NN cord-010398-5wot7tix 83 19 , , , cord-010398-5wot7tix 83 20 and and CC cord-010398-5wot7tix 83 21 modern modern JJ cord-010398-5wot7tix 83 22 genetics genetic NNS cord-010398-5wot7tix 83 23 has have VBZ cord-010398-5wot7tix 83 24 led lead VBN cord-010398-5wot7tix 83 25 to to IN cord-010398-5wot7tix 83 26 substantial substantial JJ cord-010398-5wot7tix 83 27 advances advance NNS cord-010398-5wot7tix 83 28 in in IN cord-010398-5wot7tix 83 29 understanding understand VBG cord-010398-5wot7tix 83 30 several several JJ cord-010398-5wot7tix 83 31 of of IN cord-010398-5wot7tix 83 32 these these DT cord-010398-5wot7tix 83 33 conditions condition NNS cord-010398-5wot7tix 83 34 , , , cord-010398-5wot7tix 83 35 most most RBS cord-010398-5wot7tix 83 36 notably notably RB cord-010398-5wot7tix 83 37 FM FM NNP cord-010398-5wot7tix 83 38 , , , cord-010398-5wot7tix 83 39 IBS IBS NNP cord-010398-5wot7tix 83 40 , , , cord-010398-5wot7tix 83 41 TMJD TMJD NNP cord-010398-5wot7tix 83 42 , , , cord-010398-5wot7tix 83 43 and and CC cord-010398-5wot7tix 83 44 CFS cfs NN cord-010398-5wot7tix 83 45 . . . cord-010398-5wot7tix 84 1 These these DT cord-010398-5wot7tix 84 2 advances advance NNS cord-010398-5wot7tix 84 3 have have VBP cord-010398-5wot7tix 84 4 led lead VBN cord-010398-5wot7tix 84 5 to to IN cord-010398-5wot7tix 84 6 an an DT cord-010398-5wot7tix 84 7 emerging emerge VBG cord-010398-5wot7tix 84 8 recognition recognition NN cord-010398-5wot7tix 84 9 that that WDT cord-010398-5wot7tix 84 10 chronic chronic JJ cord-010398-5wot7tix 84 11 central central JJ cord-010398-5wot7tix 84 12 pain pain NN cord-010398-5wot7tix 84 13 itself -PRON- PRP cord-010398-5wot7tix 84 14 is be VBZ cord-010398-5wot7tix 84 15 a a DT cord-010398-5wot7tix 84 16 " " `` cord-010398-5wot7tix 84 17 disease disease NN cord-010398-5wot7tix 84 18 " " '' cord-010398-5wot7tix 84 19 that that WDT cord-010398-5wot7tix 84 20 very very RB cord-010398-5wot7tix 84 21 often often RB cord-010398-5wot7tix 84 22 co co VBD cord-010398-5wot7tix 84 23 - - NN cord-010398-5wot7tix 84 24 occurs occur VBZ cord-010398-5wot7tix 84 25 with with IN cord-010398-5wot7tix 84 26 chronic chronic JJ cord-010398-5wot7tix 84 27 fatigue fatigue NN cord-010398-5wot7tix 84 28 , , , cord-010398-5wot7tix 84 29 sleep sleep NN cord-010398-5wot7tix 84 30 disturbance disturbance NN cord-010398-5wot7tix 84 31 , , , cord-010398-5wot7tix 84 32 and and CC cord-010398-5wot7tix 84 33 memory memory NN cord-010398-5wot7tix 84 34 difficulties difficulty NNS cord-010398-5wot7tix 84 35 , , , cord-010398-5wot7tix 84 36 and and CC cord-010398-5wot7tix 84 37 that that IN cord-010398-5wot7tix 84 38 many many JJ cord-010398-5wot7tix 84 39 of of IN cord-010398-5wot7tix 84 40 the the DT cord-010398-5wot7tix 84 41 underlying underlie VBG cord-010398-5wot7tix 84 42 mechanisms mechanism NNS cord-010398-5wot7tix 84 43 operative operative NN cord-010398-5wot7tix 84 44 in in IN cord-010398-5wot7tix 84 45 these these DT cord-010398-5wot7tix 84 46 heretofore heretofore RB cord-010398-5wot7tix 84 47 " " `` cord-010398-5wot7tix 84 48 idiopathic idiopathic JJ cord-010398-5wot7tix 84 49 " " '' cord-010398-5wot7tix 84 50 or or CC cord-010398-5wot7tix 84 51 " " `` cord-010398-5wot7tix 84 52 functional functional JJ cord-010398-5wot7tix 84 53 " " '' cord-010398-5wot7tix 84 54 syndromes syndrome NNS cord-010398-5wot7tix 84 55 may may MD cord-010398-5wot7tix 84 56 be be VB cord-010398-5wot7tix 84 57 similar similar JJ cord-010398-5wot7tix 84 58 , , , cord-010398-5wot7tix 84 59 no no RB cord-010398-5wot7tix 84 60 matter matter RB cord-010398-5wot7tix 84 61 whether whether IN cord-010398-5wot7tix 84 62 the the DT cord-010398-5wot7tix 84 63 pain pain NN cord-010398-5wot7tix 84 64 is be VBZ cord-010398-5wot7tix 84 65 present present JJ cord-010398-5wot7tix 84 66 throughout throughout IN cord-010398-5wot7tix 84 67 the the DT cord-010398-5wot7tix 84 68 body body NN cord-010398-5wot7tix 84 69 ( ( -LRB- cord-010398-5wot7tix 84 70 eg eg RB cord-010398-5wot7tix 84 71 , , , cord-010398-5wot7tix 84 72 in in IN cord-010398-5wot7tix 84 73 FM FM NNP cord-010398-5wot7tix 84 74 ) ) -RRB- cord-010398-5wot7tix 84 75 , , , cord-010398-5wot7tix 84 76 or or CC cord-010398-5wot7tix 84 77 localized localize VBN cord-010398-5wot7tix 84 78 to to IN cord-010398-5wot7tix 84 79 the the DT cord-010398-5wot7tix 84 80 low low JJ cord-010398-5wot7tix 84 81 back back RB cord-010398-5wot7tix 84 82 , , , cord-010398-5wot7tix 84 83 the the DT cord-010398-5wot7tix 84 84 bowel bowel NN cord-010398-5wot7tix 84 85 , , , cord-010398-5wot7tix 84 86 or or CC cord-010398-5wot7tix 84 87 the the DT cord-010398-5wot7tix 84 88 bladder bladder NN cord-010398-5wot7tix 84 89 . . . cord-010398-5wot7tix 85 1 Furthermore furthermore RB cord-010398-5wot7tix 85 2 , , , cord-010398-5wot7tix 85 3 most most JJS cord-010398-5wot7tix 85 4 investigators investigator NNS cord-010398-5wot7tix 85 5 believe believe VBP cord-010398-5wot7tix 85 6 that that IN cord-010398-5wot7tix 85 7 the the DT cord-010398-5wot7tix 85 8 neurobiological neurobiological JJ cord-010398-5wot7tix 85 9 underpinnings underpinning NNS cord-010398-5wot7tix 85 10 of of IN cord-010398-5wot7tix 85 11 these these DT cord-010398-5wot7tix 85 12 conditions condition NNS cord-010398-5wot7tix 85 13 undermine undermine VBP cord-010398-5wot7tix 85 14 the the DT cord-010398-5wot7tix 85 15 psychiatric psychiatric JJ cord-010398-5wot7tix 85 16 construct construct NN cord-010398-5wot7tix 85 17 of of IN cord-010398-5wot7tix 85 18 " " `` cord-010398-5wot7tix 85 19 somatization somatization NN cord-010398-5wot7tix 85 20 , , , cord-010398-5wot7tix 85 21 " " '' cord-010398-5wot7tix 85 22 at at IN cord-010398-5wot7tix 85 23 least least JJS cord-010398-5wot7tix 85 24 if if IN cord-010398-5wot7tix 85 25 it -PRON- PRP cord-010398-5wot7tix 85 26 is be VBZ cord-010398-5wot7tix 85 27 implied imply VBN cord-010398-5wot7tix 85 28 that that IN cord-010398-5wot7tix 85 29 these these DT cord-010398-5wot7tix 85 30 phenomena phenomenon NNS cord-010398-5wot7tix 85 31 are be VBP cord-010398-5wot7tix 85 32 the the DT cord-010398-5wot7tix 85 33 somatic somatic JJ cord-010398-5wot7tix 85 34 representation representation NN cord-010398-5wot7tix 85 35 of of IN cord-010398-5wot7tix 85 36 psychological psychological JJ cord-010398-5wot7tix 85 37 distress distress NN cord-010398-5wot7tix 85 38 with with IN cord-010398-5wot7tix 85 39 no no DT cord-010398-5wot7tix 85 40 " " `` cord-010398-5wot7tix 85 41 real real JJ cord-010398-5wot7tix 85 42 " " '' cord-010398-5wot7tix 85 43 pathological pathological JJ cord-010398-5wot7tix 85 44 basis basis NN cord-010398-5wot7tix 85 45 . . . cord-010398-5wot7tix 86 1 Figure figure NN cord-010398-5wot7tix 86 2 2 2 CD cord-010398-5wot7tix 86 3 shows show VBZ cord-010398-5wot7tix 86 4 a a DT cord-010398-5wot7tix 86 5 theoretical theoretical JJ cord-010398-5wot7tix 86 6 schema schema NN cord-010398-5wot7tix 86 7 for for IN cord-010398-5wot7tix 86 8 classifying classify VBG cord-010398-5wot7tix 86 9 pain pain NN cord-010398-5wot7tix 86 10 syndromes syndrome NNS cord-010398-5wot7tix 86 11 on on IN cord-010398-5wot7tix 86 12 the the DT cord-010398-5wot7tix 86 13 basis basis NN cord-010398-5wot7tix 86 14 of of IN cord-010398-5wot7tix 86 15 their -PRON- PRP$ cord-010398-5wot7tix 86 16 underlying underlying JJ cord-010398-5wot7tix 86 17 mechanisms mechanism NNS cord-010398-5wot7tix 86 18 . . . cord-010398-5wot7tix 87 1 It -PRON- PRP cord-010398-5wot7tix 87 2 is be VBZ cord-010398-5wot7tix 87 3 important important JJ cord-010398-5wot7tix 87 4 to to TO cord-010398-5wot7tix 87 5 recognize recognize VB cord-010398-5wot7tix 87 6 that that IN cord-010398-5wot7tix 87 7 even even RB cord-010398-5wot7tix 87 8 patients patient NNS cord-010398-5wot7tix 87 9 with with IN cord-010398-5wot7tix 87 10 " " `` cord-010398-5wot7tix 87 11 peripheral peripheral JJ cord-010398-5wot7tix 87 12 " " '' cord-010398-5wot7tix 87 13 pain pain NN cord-010398-5wot7tix 87 14 syndromes syndrome NNS cord-010398-5wot7tix 87 15 such such JJ cord-010398-5wot7tix 87 16 as as IN cord-010398-5wot7tix 87 17 osteoarthritis osteoarthritis NN cord-010398-5wot7tix 87 18 or or CC cord-010398-5wot7tix 87 19 rheumatoid rheumatoid NN cord-010398-5wot7tix 87 20 arthritis arthritis NN cord-010398-5wot7tix 87 21 will will MD cord-010398-5wot7tix 87 22 often often RB cord-010398-5wot7tix 87 23 have have VB cord-010398-5wot7tix 87 24 elements element NNS cord-010398-5wot7tix 87 25 of of IN cord-010398-5wot7tix 87 26 central central JJ cord-010398-5wot7tix 87 27 pain pain NN cord-010398-5wot7tix 87 28 that that WDT cord-010398-5wot7tix 87 29 need need VBP cord-010398-5wot7tix 87 30 to to TO cord-010398-5wot7tix 87 31 be be VB cord-010398-5wot7tix 87 32 treated treat VBN cord-010398-5wot7tix 87 33 as as IN cord-010398-5wot7tix 87 34 such such JJ cord-010398-5wot7tix 87 35 , , , cord-010398-5wot7tix 87 36 which which WDT cord-010398-5wot7tix 87 37 is be VBZ cord-010398-5wot7tix 87 38 why why WRB cord-010398-5wot7tix 87 39 this this DT cord-010398-5wot7tix 87 40 construct construct NN cord-010398-5wot7tix 87 41 has have VBZ cord-010398-5wot7tix 87 42 moved move VBN cord-010398-5wot7tix 87 43 well well RB cord-010398-5wot7tix 87 44 beyond beyond IN cord-010398-5wot7tix 87 45 simple simple JJ cord-010398-5wot7tix 87 46 relevance relevance NN cord-010398-5wot7tix 87 47 to to IN cord-010398-5wot7tix 87 48 functional functional JJ cord-010398-5wot7tix 87 49 somatic somatic JJ cord-010398-5wot7tix 87 50 syndromes syndrome NNS cord-010398-5wot7tix 87 51 . . . cord-010398-5wot7tix 88 1 The the DT cord-010398-5wot7tix 88 2 current current JJ cord-010398-5wot7tix 88 3 thinking thinking NN cord-010398-5wot7tix 88 4 about about IN cord-010398-5wot7tix 88 5 these these DT cord-010398-5wot7tix 88 6 overlapping overlap VBG cord-010398-5wot7tix 88 7 symptoms symptom NNS cord-010398-5wot7tix 88 8 and and CC cord-010398-5wot7tix 88 9 syndromes syndrome NNS cord-010398-5wot7tix 88 10 is be VBZ cord-010398-5wot7tix 88 11 as as IN cord-010398-5wot7tix 88 12 follows follow VBZ cord-010398-5wot7tix 88 13 , , , cord-010398-5wot7tix 88 14 and and CC cord-010398-5wot7tix 88 15 will will MD cord-010398-5wot7tix 88 16 be be VB cord-010398-5wot7tix 88 17 reviewed review VBN cord-010398-5wot7tix 88 18 in in IN cord-010398-5wot7tix 88 19 greater great JJR cord-010398-5wot7tix 88 20 detail detail NN cord-010398-5wot7tix 88 21 : : : cord-010398-5wot7tix 89 1 • • NNP cord-010398-5wot7tix 90 1 The the DT cord-010398-5wot7tix 90 2 core core NN cord-010398-5wot7tix 90 3 symptoms symptom NNS cord-010398-5wot7tix 90 4 seen see VBN cord-010398-5wot7tix 90 5 in in IN cord-010398-5wot7tix 90 6 patients patient NNS cord-010398-5wot7tix 90 7 with with IN cord-010398-5wot7tix 90 8 these these DT cord-010398-5wot7tix 90 9 illnesses illness NNS cord-010398-5wot7tix 90 10 are be VBP cord-010398-5wot7tix 90 11 multifocal multifocal JJ cord-010398-5wot7tix 90 12 pain pain NN cord-010398-5wot7tix 90 13 , , , cord-010398-5wot7tix 90 14 fatigue fatigue NN cord-010398-5wot7tix 90 15 , , , cord-010398-5wot7tix 90 16 insomnia insomnia NN cord-010398-5wot7tix 90 17 , , , cord-010398-5wot7tix 90 18 cognitive cognitive JJ cord-010398-5wot7tix 90 19 or or CC cord-010398-5wot7tix 90 20 memory memory NN cord-010398-5wot7tix 90 21 problems problem NNS cord-010398-5wot7tix 90 22 , , , cord-010398-5wot7tix 90 23 and and CC cord-010398-5wot7tix 90 24 , , , cord-010398-5wot7tix 90 25 in in IN cord-010398-5wot7tix 90 26 many many JJ cord-010398-5wot7tix 90 27 cases case NNS cord-010398-5wot7tix 90 28 , , , cord-010398-5wot7tix 90 29 psychological psychological JJ cord-010398-5wot7tix 90 30 distress distress NN cord-010398-5wot7tix 90 31 [ [ -LRB- cord-010398-5wot7tix 90 32 9 9 CD cord-010398-5wot7tix 90 33 , , , cord-010398-5wot7tix 90 34 39 39 CD cord-010398-5wot7tix 90 35 ] ] -RRB- cord-010398-5wot7tix 90 36 . . . cord-010398-5wot7tix 91 1 Some some DT cord-010398-5wot7tix 91 2 patients patient NNS cord-010398-5wot7tix 91 3 in in IN cord-010398-5wot7tix 91 4 the the DT cord-010398-5wot7tix 91 5 population population NN cord-010398-5wot7tix 91 6 only only RB cord-010398-5wot7tix 91 7 have have VBP cord-010398-5wot7tix 91 8 one one CD cord-010398-5wot7tix 91 9 of of IN cord-010398-5wot7tix 91 10 these these DT cord-010398-5wot7tix 91 11 symptoms symptom NNS cord-010398-5wot7tix 91 12 , , , cord-010398-5wot7tix 91 13 but but CC cord-010398-5wot7tix 91 14 more more RBR cord-010398-5wot7tix 91 15 often often RB cord-010398-5wot7tix 91 16 patients patient NNS cord-010398-5wot7tix 91 17 have have VBP cord-010398-5wot7tix 91 18 many many JJ cord-010398-5wot7tix 91 19 , , , cord-010398-5wot7tix 91 20 and and CC cord-010398-5wot7tix 91 21 the the DT cord-010398-5wot7tix 91 22 precise precise JJ cord-010398-5wot7tix 91 23 location location NN cord-010398-5wot7tix 91 24 of of IN cord-010398-5wot7tix 91 25 the the DT cord-010398-5wot7tix 91 26 pain pain NN cord-010398-5wot7tix 91 27 , , , cord-010398-5wot7tix 91 28 and and CC cord-010398-5wot7tix 91 29 the the DT cord-010398-5wot7tix 91 30 severity severity NN cord-010398-5wot7tix 91 31 and and CC cord-010398-5wot7tix 91 32 quality quality NN cord-010398-5wot7tix 91 33 of of IN cord-010398-5wot7tix 91 34 the the DT cord-010398-5wot7tix 91 35 fatigue fatigue NN cord-010398-5wot7tix 91 36 , , , cord-010398-5wot7tix 91 37 changes change VBZ cord-010398-5wot7tix 91 38 over over IN cord-010398-5wot7tix 91 39 time time NN cord-010398-5wot7tix 91 40 . . . cord-010398-5wot7tix 92 1 Thus thus RB cord-010398-5wot7tix 92 2 , , , cord-010398-5wot7tix 92 3 in in IN cord-010398-5wot7tix 92 4 clinical clinical JJ cord-010398-5wot7tix 92 5 practice practice NN cord-010398-5wot7tix 92 6 it -PRON- PRP cord-010398-5wot7tix 92 7 is be VBZ cord-010398-5wot7tix 92 8 useful useful JJ cord-010398-5wot7tix 92 9 to to TO cord-010398-5wot7tix 92 10 evaluate evaluate VB cord-010398-5wot7tix 92 11 patients patient NNS cord-010398-5wot7tix 92 12 with with IN cord-010398-5wot7tix 92 13 idiopathic idiopathic JJ cord-010398-5wot7tix 92 14 fatigue fatigue NN cord-010398-5wot7tix 92 15 regarding regard VBG cord-010398-5wot7tix 92 16 fatigue fatigue NN cord-010398-5wot7tix 92 17 , , , cord-010398-5wot7tix 92 18 pain pain NN cord-010398-5wot7tix 92 19 , , , cord-010398-5wot7tix 92 20 and and CC cord-010398-5wot7tix 92 21 sleep sleep NN cord-010398-5wot7tix 92 22 disturbances disturbance NNS cord-010398-5wot7tix 92 23 during during IN cord-010398-5wot7tix 92 24 the the DT cord-010398-5wot7tix 92 25 course course NN cord-010398-5wot7tix 92 26 of of IN cord-010398-5wot7tix 92 27 their -PRON- PRP$ cord-010398-5wot7tix 92 28 lifetime lifetime NN cord-010398-5wot7tix 92 29 . . . cord-010398-5wot7tix 93 1 It -PRON- PRP cord-010398-5wot7tix 93 2 may may MD cord-010398-5wot7tix 93 3 be be VB cord-010398-5wot7tix 93 4 that that IN cord-010398-5wot7tix 93 5 when when WRB cord-010398-5wot7tix 93 6 patients patient NNS cord-010398-5wot7tix 93 7 have have VBP cord-010398-5wot7tix 93 8 this this DT cord-010398-5wot7tix 93 9 pattern pattern NN cord-010398-5wot7tix 93 10 of of IN cord-010398-5wot7tix 93 11 symptoms symptom NNS cord-010398-5wot7tix 93 12 and and CC cord-010398-5wot7tix 93 13 past past JJ cord-010398-5wot7tix 93 14 diagnoses diagnosis NNS cord-010398-5wot7tix 93 15 , , , cord-010398-5wot7tix 93 16 then then RB cord-010398-5wot7tix 93 17 they -PRON- PRP cord-010398-5wot7tix 93 18 have have VBP cord-010398-5wot7tix 93 19 a a DT cord-010398-5wot7tix 93 20 FM FM NNP cord-010398-5wot7tix 93 21 - - HYPH cord-010398-5wot7tix 93 22 like like JJ cord-010398-5wot7tix 93 23 central central JJ cord-010398-5wot7tix 93 24 pain pain NN cord-010398-5wot7tix 93 25 syndrome syndrome NN cord-010398-5wot7tix 93 26 , , , cord-010398-5wot7tix 93 27 and and CC cord-010398-5wot7tix 93 28 if if IN cord-010398-5wot7tix 93 29 not not RB cord-010398-5wot7tix 93 30 , , , cord-010398-5wot7tix 93 31 then then RB cord-010398-5wot7tix 93 32 other other JJ cord-010398-5wot7tix 93 33 reasons reason NNS cord-010398-5wot7tix 93 34 for for IN cord-010398-5wot7tix 93 35 fatigue fatigue NN cord-010398-5wot7tix 93 36 must must MD cord-010398-5wot7tix 93 37 be be VB cord-010398-5wot7tix 93 38 more more RBR cord-010398-5wot7tix 93 39 strongly strongly RB cord-010398-5wot7tix 93 40 considered consider VBN cord-010398-5wot7tix 93 41 . . . cord-010398-5wot7tix 94 1 • • NNP cord-010398-5wot7tix 95 1 The the DT cord-010398-5wot7tix 95 2 presence presence NN cord-010398-5wot7tix 95 3 and and CC cord-010398-5wot7tix 95 4 severity severity NN cord-010398-5wot7tix 95 5 of of IN cord-010398-5wot7tix 95 6 these these DT cord-010398-5wot7tix 95 7 symptoms symptom NNS cord-010398-5wot7tix 95 8 vary vary VBP cord-010398-5wot7tix 95 9 across across IN cord-010398-5wot7tix 95 10 populations population NNS cord-010398-5wot7tix 95 11 . . . cord-010398-5wot7tix 96 1 All all DT cord-010398-5wot7tix 96 2 of of IN cord-010398-5wot7tix 96 3 the the DT cord-010398-5wot7tix 96 4 diagnostic diagnostic JJ cord-010398-5wot7tix 96 5 labels label NNS cord-010398-5wot7tix 96 6 in in IN cord-010398-5wot7tix 96 7 current current JJ cord-010398-5wot7tix 96 8 use use NN cord-010398-5wot7tix 96 9 are be VBP cord-010398-5wot7tix 96 10 to to IN cord-010398-5wot7tix 96 11 some some DT cord-010398-5wot7tix 96 12 degree degree NN cord-010398-5wot7tix 96 13 arbitrary arbitrary JJ cord-010398-5wot7tix 96 14 because because IN cord-010398-5wot7tix 96 15 there there EX cord-010398-5wot7tix 96 16 is be VBZ cord-010398-5wot7tix 96 17 no no DT cord-010398-5wot7tix 96 18 objective objective JJ cord-010398-5wot7tix 96 19 tissue tissue NN cord-010398-5wot7tix 96 20 pathology pathology NN cord-010398-5wot7tix 96 21 or or CC cord-010398-5wot7tix 96 22 gold gold NN cord-010398-5wot7tix 96 23 standard standard NN cord-010398-5wot7tix 96 24 to to TO cord-010398-5wot7tix 96 25 which which WDT cord-010398-5wot7tix 96 26 " " `` cord-010398-5wot7tix 96 27 disease disease NN cord-010398-5wot7tix 96 28 " " '' cord-010398-5wot7tix 96 29 can can MD cord-010398-5wot7tix 96 30 be be VB cord-010398-5wot7tix 96 31 anchored anchor VBN cord-010398-5wot7tix 96 32 . . . cord-010398-5wot7tix 97 1 • • NNP cord-010398-5wot7tix 98 1 These these DT cord-010398-5wot7tix 98 2 symptoms symptom NNS cord-010398-5wot7tix 98 3 and and CC cord-010398-5wot7tix 98 4 syndromes syndrome NNS cord-010398-5wot7tix 98 5 occur occur VBP cord-010398-5wot7tix 98 6 approximately approximately RB cord-010398-5wot7tix 98 7 1.5 1.5 CD cord-010398-5wot7tix 98 8 to to TO cord-010398-5wot7tix 98 9 2 2 CD cord-010398-5wot7tix 98 10 times time NNS cord-010398-5wot7tix 98 11 more more RBR cord-010398-5wot7tix 98 12 commonly commonly RB cord-010398-5wot7tix 98 13 in in IN cord-010398-5wot7tix 98 14 women woman NNS cord-010398-5wot7tix 98 15 than than IN cord-010398-5wot7tix 98 16 men man NNS cord-010398-5wot7tix 98 17 . . . cord-010398-5wot7tix 99 1 The the DT cord-010398-5wot7tix 99 2 gender gender NN cord-010398-5wot7tix 99 3 difference difference NN cord-010398-5wot7tix 99 4 appears appear VBZ cord-010398-5wot7tix 99 5 more more RBR cord-010398-5wot7tix 99 6 apparent apparent JJ cord-010398-5wot7tix 99 7 in in IN cord-010398-5wot7tix 99 8 clinical clinical JJ cord-010398-5wot7tix 99 9 samples sample NNS cord-010398-5wot7tix 99 10 ( ( -LRB- cord-010398-5wot7tix 99 11 especially especially RB cord-010398-5wot7tix 99 12 tertiary tertiary JJ cord-010398-5wot7tix 99 13 care care NN cord-010398-5wot7tix 99 14 ) ) -RRB- cord-010398-5wot7tix 99 15 , , , cord-010398-5wot7tix 99 16 however however RB cord-010398-5wot7tix 99 17 , , , cord-010398-5wot7tix 99 18 than than IN cord-010398-5wot7tix 99 19 in in IN cord-010398-5wot7tix 99 20 populationbased populationbased JJ cord-010398-5wot7tix 99 21 samples sample NNS cord-010398-5wot7tix 99 22 [ [ -LRB- cord-010398-5wot7tix 99 23 37 37 CD cord-010398-5wot7tix 99 24 , , , cord-010398-5wot7tix 99 25 38 38 CD cord-010398-5wot7tix 99 26 ] ] -RRB- cord-010398-5wot7tix 99 27 . . . cord-010398-5wot7tix 100 1 • • NNP cord-010398-5wot7tix 101 1 There there EX cord-010398-5wot7tix 101 2 is be VBZ cord-010398-5wot7tix 101 3 a a DT cord-010398-5wot7tix 101 4 strong strong JJ cord-010398-5wot7tix 101 5 familial familial JJ cord-010398-5wot7tix 101 6 predisposition predisposition NN cord-010398-5wot7tix 101 7 to to IN cord-010398-5wot7tix 101 8 these these DT cord-010398-5wot7tix 101 9 symptoms symptom NNS cord-010398-5wot7tix 101 10 and and CC cord-010398-5wot7tix 101 11 illnesses illness NNS cord-010398-5wot7tix 101 12 , , , cord-010398-5wot7tix 101 13 and and CC cord-010398-5wot7tix 101 14 studies study NNS cord-010398-5wot7tix 101 15 clearly clearly RB cord-010398-5wot7tix 101 16 show show VBP cord-010398-5wot7tix 101 17 that that IN cord-010398-5wot7tix 101 18 these these DT cord-010398-5wot7tix 101 19 somatic somatic JJ cord-010398-5wot7tix 101 20 symptoms symptom NNS cord-010398-5wot7tix 101 21 and and CC cord-010398-5wot7tix 101 22 syndromes syndrome NNS cord-010398-5wot7tix 101 23 are be VBP cord-010398-5wot7tix 101 24 separable separable JJ cord-010398-5wot7tix 101 25 from from IN cord-010398-5wot7tix 101 26 depression depression NN cord-010398-5wot7tix 101 27 and and CC cord-010398-5wot7tix 101 28 other other JJ cord-010398-5wot7tix 101 29 psychiatric psychiatric JJ cord-010398-5wot7tix 101 30 disorders disorder NNS cord-010398-5wot7tix 101 31 [ [ -LRB- cord-010398-5wot7tix 101 32 39 39 CD cord-010398-5wot7tix 101 33 ] ] -RRB- cord-010398-5wot7tix 101 34 [ [ -LRB- cord-010398-5wot7tix 101 35 40 40 CD cord-010398-5wot7tix 101 36 ] ] -RRB- cord-010398-5wot7tix 101 37 [ [ -LRB- cord-010398-5wot7tix 101 38 41 41 CD cord-010398-5wot7tix 101 39 ] ] -RRB- cord-010398-5wot7tix 101 40 . . . cord-010398-5wot7tix 102 1 • • NNP cord-010398-5wot7tix 102 2 A a DT cord-010398-5wot7tix 102 3 variety variety NN cord-010398-5wot7tix 102 4 of of IN cord-010398-5wot7tix 102 5 biological biological JJ cord-010398-5wot7tix 102 6 stressors stressor NNS cord-010398-5wot7tix 102 7 appear appear VBP cord-010398-5wot7tix 102 8 to to TO cord-010398-5wot7tix 102 9 be be VB cord-010398-5wot7tix 102 10 capable capable JJ cord-010398-5wot7tix 102 11 of of IN cord-010398-5wot7tix 102 12 either either DT cord-010398-5wot7tix 102 13 triggering triggering JJ cord-010398-5wot7tix 102 14 or or CC cord-010398-5wot7tix 102 15 exacerbating exacerbate VBG cord-010398-5wot7tix 102 16 these these DT cord-010398-5wot7tix 102 17 symptoms symptom NNS cord-010398-5wot7tix 102 18 and and CC cord-010398-5wot7tix 102 19 illnesses illness NNS cord-010398-5wot7tix 102 20 , , , cord-010398-5wot7tix 102 21 including include VBG cord-010398-5wot7tix 102 22 physical physical JJ cord-010398-5wot7tix 102 23 trauma trauma NN cord-010398-5wot7tix 102 24 , , , cord-010398-5wot7tix 102 25 infections infection NNS cord-010398-5wot7tix 102 26 , , , cord-010398-5wot7tix 102 27 early early JJ cord-010398-5wot7tix 102 28 life life NN cord-010398-5wot7tix 102 29 trauma trauma NN cord-010398-5wot7tix 102 30 , , , cord-010398-5wot7tix 102 31 and and CC cord-010398-5wot7tix 102 32 deployment deployment NN cord-010398-5wot7tix 102 33 to to IN cord-010398-5wot7tix 102 34 war war NN cord-010398-5wot7tix 102 35 , , , cord-010398-5wot7tix 102 36 in in IN cord-010398-5wot7tix 102 37 addition addition NN cord-010398-5wot7tix 102 38 to to IN cord-010398-5wot7tix 102 39 some some DT cord-010398-5wot7tix 102 40 other other JJ cord-010398-5wot7tix 102 41 types type NNS cord-010398-5wot7tix 102 42 of of IN cord-010398-5wot7tix 102 43 psychological psychological JJ cord-010398-5wot7tix 102 44 stressors stressor NNS cord-010398-5wot7tix 102 45 ( ( -LRB- cord-010398-5wot7tix 102 46 eg eg IN cord-010398-5wot7tix 102 47 , , , cord-010398-5wot7tix 102 48 there there EX cord-010398-5wot7tix 102 49 was be VBD cord-010398-5wot7tix 102 50 no no DT cord-010398-5wot7tix 102 51 increase increase NN cord-010398-5wot7tix 102 52 in in IN cord-010398-5wot7tix 102 53 somatic somatic JJ cord-010398-5wot7tix 102 54 symptoms symptom NNS cord-010398-5wot7tix 102 55 or or CC cord-010398-5wot7tix 102 56 worsening worsening NN cord-010398-5wot7tix 102 57 of of IN cord-010398-5wot7tix 102 58 FM FM NNP cord-010398-5wot7tix 102 59 after after IN cord-010398-5wot7tix 102 60 the the DT cord-010398-5wot7tix 102 61 terrorist terrorist JJ cord-010398-5wot7tix 102 62 attacks attack NNS cord-010398-5wot7tix 102 63 of of IN cord-010398-5wot7tix 102 64 9/11 9/11 CD cord-010398-5wot7tix 102 65 ) ) -RRB- cord-010398-5wot7tix 103 1 [ [ -LRB- cord-010398-5wot7tix 103 2 42 42 CD cord-010398-5wot7tix 103 3 , , , cord-010398-5wot7tix 103 4 43 43 CD cord-010398-5wot7tix 103 5 ] ] -RRB- cord-010398-5wot7tix 103 6 . . . cord-010398-5wot7tix 104 1 • • NNP cord-010398-5wot7tix 105 1 Groups group NNS cord-010398-5wot7tix 105 2 of of IN cord-010398-5wot7tix 105 3 patients patient NNS cord-010398-5wot7tix 105 4 with with IN cord-010398-5wot7tix 105 5 these these DT cord-010398-5wot7tix 105 6 conditions condition NNS cord-010398-5wot7tix 105 7 ( ( -LRB- cord-010398-5wot7tix 105 8 eg eg RB cord-010398-5wot7tix 105 9 , , , cord-010398-5wot7tix 105 10 FM FM NNP cord-010398-5wot7tix 105 11 , , , cord-010398-5wot7tix 105 12 IBS IBS NNP cord-010398-5wot7tix 105 13 , , , cord-010398-5wot7tix 105 14 chronic chronic JJ cord-010398-5wot7tix 105 15 headache headache NN cord-010398-5wot7tix 105 16 , , , cord-010398-5wot7tix 105 17 TMJD TMJD NNP cord-010398-5wot7tix 105 18 , , , cord-010398-5wot7tix 105 19 CFS CFS NNP cord-010398-5wot7tix 105 20 ) ) -RRB- cord-010398-5wot7tix 105 21 display display NN cord-010398-5wot7tix 105 22 diffuse diffuse NN cord-010398-5wot7tix 105 23 hyperalgesia hyperalgesia NN cord-010398-5wot7tix 105 24 ( ( -LRB- cord-010398-5wot7tix 105 25 increased increase VBN cord-010398-5wot7tix 105 26 pain pain NN cord-010398-5wot7tix 105 27 in in IN cord-010398-5wot7tix 105 28 response response NN cord-010398-5wot7tix 105 29 to to IN cord-010398-5wot7tix 105 30 normally normally RB cord-010398-5wot7tix 105 31 painful painful JJ cord-010398-5wot7tix 105 32 stimuli stimulus NNS cord-010398-5wot7tix 105 33 ) ) -RRB- cord-010398-5wot7tix 105 34 and/or and/or CC cord-010398-5wot7tix 105 35 allodynia allodynia NN cord-010398-5wot7tix 105 36 ( ( -LRB- cord-010398-5wot7tix 105 37 pain pain NN cord-010398-5wot7tix 105 38 in in IN cord-010398-5wot7tix 105 39 response response NN cord-010398-5wot7tix 105 40 to to TO cord-010398-5wot7tix 105 41 normally normally RB cord-010398-5wot7tix 105 42 nonpainful nonpainful JJ cord-010398-5wot7tix 105 43 stimuli stimulus NNS cord-010398-5wot7tix 105 44 ) ) -RRB- cord-010398-5wot7tix 105 45 . . . cord-010398-5wot7tix 106 1 Many many JJ cord-010398-5wot7tix 106 2 patients patient NNS cord-010398-5wot7tix 106 3 with with IN cord-010398-5wot7tix 106 4 these these DT cord-010398-5wot7tix 106 5 conditions condition NNS cord-010398-5wot7tix 106 6 also also RB cord-010398-5wot7tix 106 7 have have VBP cord-010398-5wot7tix 106 8 been be VBN cord-010398-5wot7tix 106 9 shown show VBN cord-010398-5wot7tix 106 10 to to TO cord-010398-5wot7tix 106 11 demonstrate demonstrate VB cord-010398-5wot7tix 106 12 more more JJR cord-010398-5wot7tix 106 13 sensitivity sensitivity NN cord-010398-5wot7tix 106 14 to to IN cord-010398-5wot7tix 106 15 many many JJ cord-010398-5wot7tix 106 16 stimuli stimulus NNS cord-010398-5wot7tix 106 17 other other JJ cord-010398-5wot7tix 106 18 than than IN cord-010398-5wot7tix 106 19 pain pain NN cord-010398-5wot7tix 106 20 ( ( -LRB- cord-010398-5wot7tix 106 21 ie ie FW cord-010398-5wot7tix 106 22 , , , cord-010398-5wot7tix 106 23 auditory auditory JJ cord-010398-5wot7tix 106 24 , , , cord-010398-5wot7tix 106 25 visual visual JJ cord-010398-5wot7tix 106 26 ) ) -RRB- cord-010398-5wot7tix 106 27 , , , cord-010398-5wot7tix 106 28 and and CC cord-010398-5wot7tix 106 29 data datum NNS cord-010398-5wot7tix 106 30 suggest suggest VBP cord-010398-5wot7tix 106 31 that that IN cord-010398-5wot7tix 106 32 these these DT cord-010398-5wot7tix 106 33 patients patient NNS cord-010398-5wot7tix 106 34 have have VBP cord-010398-5wot7tix 106 35 a a DT cord-010398-5wot7tix 106 36 fundamental fundamental JJ cord-010398-5wot7tix 106 37 problem problem NN cord-010398-5wot7tix 106 38 with with IN cord-010398-5wot7tix 106 39 pain pain NN cord-010398-5wot7tix 106 40 or or CC cord-010398-5wot7tix 106 41 sensory sensory JJ cord-010398-5wot7tix 106 42 processing processing NN cord-010398-5wot7tix 106 43 rather rather RB cord-010398-5wot7tix 106 44 than than IN cord-010398-5wot7tix 106 45 an an DT cord-010398-5wot7tix 106 46 abnormality abnormality NN cord-010398-5wot7tix 106 47 confined confine VBN cord-010398-5wot7tix 106 48 to to IN cord-010398-5wot7tix 106 49 the the DT cord-010398-5wot7tix 106 50 specific specific JJ cord-010398-5wot7tix 106 51 body body NN cord-010398-5wot7tix 106 52 region region NN cord-010398-5wot7tix 106 53 in in IN cord-010398-5wot7tix 106 54 which which WDT cord-010398-5wot7tix 106 55 the the DT cord-010398-5wot7tix 106 56 pain pain NN cord-010398-5wot7tix 106 57 is be VBZ cord-010398-5wot7tix 106 58 being be VBG cord-010398-5wot7tix 106 59 experienced experience VBN cord-010398-5wot7tix 106 60 . . . cord-010398-5wot7tix 107 1 In in IN cord-010398-5wot7tix 107 2 fact fact NN cord-010398-5wot7tix 107 3 , , , cord-010398-5wot7tix 107 4 the the DT cord-010398-5wot7tix 107 5 expanded expand VBN cord-010398-5wot7tix 107 6 relevance relevance NN cord-010398-5wot7tix 107 7 of of IN cord-010398-5wot7tix 107 8 the the DT cord-010398-5wot7tix 107 9 FM FM NNP cord-010398-5wot7tix 107 10 construct construct NN cord-010398-5wot7tix 107 11 relates relate VBZ cord-010398-5wot7tix 107 12 to to IN cord-010398-5wot7tix 107 13 the the DT cord-010398-5wot7tix 107 14 idea idea NN cord-010398-5wot7tix 107 15 that that IN cord-010398-5wot7tix 107 16 all all DT cord-010398-5wot7tix 107 17 patients patient NNS cord-010398-5wot7tix 107 18 ( ( -LRB- cord-010398-5wot7tix 107 19 with with IN cord-010398-5wot7tix 107 20 and and CC cord-010398-5wot7tix 107 21 without without IN cord-010398-5wot7tix 107 22 pain pain NN cord-010398-5wot7tix 107 23 ) ) -RRB- cord-010398-5wot7tix 107 24 have have VBP cord-010398-5wot7tix 107 25 different different JJ cord-010398-5wot7tix 107 26 " " `` cord-010398-5wot7tix 107 27 volume volume NN cord-010398-5wot7tix 107 28 control control NN cord-010398-5wot7tix 107 29 " " '' cord-010398-5wot7tix 107 30 settings setting NNS cord-010398-5wot7tix 107 31 on on IN cord-010398-5wot7tix 107 32 their -PRON- PRP$ cord-010398-5wot7tix 107 33 pain pain NN cord-010398-5wot7tix 107 34 and and CC cord-010398-5wot7tix 107 35 sensory sensory JJ cord-010398-5wot7tix 107 36 processing processing NN cord-010398-5wot7tix 107 37 . . . cord-010398-5wot7tix 108 1 The the DT cord-010398-5wot7tix 108 2 position position NN cord-010398-5wot7tix 108 3 on on IN cord-010398-5wot7tix 108 4 this this DT cord-010398-5wot7tix 108 5 bell bell NN cord-010398-5wot7tix 108 6 - - HYPH cord-010398-5wot7tix 108 7 shaped shape VBN cord-010398-5wot7tix 108 8 curve curve NN cord-010398-5wot7tix 108 9 of of IN cord-010398-5wot7tix 108 10 pain pain NN cord-010398-5wot7tix 108 11 or or CC cord-010398-5wot7tix 108 12 sensory sensory JJ cord-010398-5wot7tix 108 13 sensitivity sensitivity NN cord-010398-5wot7tix 108 14 largely largely RB cord-010398-5wot7tix 108 15 determines determine VBZ cord-010398-5wot7tix 108 16 whether whether IN cord-010398-5wot7tix 108 17 they -PRON- PRP cord-010398-5wot7tix 108 18 will will MD cord-010398-5wot7tix 108 19 have have VB cord-010398-5wot7tix 108 20 pain pain NN cord-010398-5wot7tix 108 21 or or CC cord-010398-5wot7tix 108 22 other other JJ cord-010398-5wot7tix 108 23 sensory sensory JJ cord-010398-5wot7tix 108 24 symptoms symptom NNS cord-010398-5wot7tix 108 25 during during IN cord-010398-5wot7tix 108 26 the the DT cord-010398-5wot7tix 108 27 course course NN cord-010398-5wot7tix 108 28 of of IN cord-010398-5wot7tix 108 29 their -PRON- PRP$ cord-010398-5wot7tix 108 30 lifetime lifetime NN cord-010398-5wot7tix 108 31 and and CC cord-010398-5wot7tix 108 32 how how WRB cord-010398-5wot7tix 108 33 severe severe JJ cord-010398-5wot7tix 108 34 these these DT cord-010398-5wot7tix 108 35 symptoms symptom NNS cord-010398-5wot7tix 108 36 will will MD cord-010398-5wot7tix 108 37 be be VB cord-010398-5wot7tix 108 38 . . . cord-010398-5wot7tix 109 1 • • NNP cord-010398-5wot7tix 110 1 In in IN cord-010398-5wot7tix 110 2 addition addition NN cord-010398-5wot7tix 110 3 to to IN cord-010398-5wot7tix 110 4 pain pain NN cord-010398-5wot7tix 110 5 and and CC cord-010398-5wot7tix 110 6 sensory sensory JJ cord-010398-5wot7tix 110 7 amplification amplification NN cord-010398-5wot7tix 110 8 , , , cord-010398-5wot7tix 110 9 other other JJ cord-010398-5wot7tix 110 10 shared share VBD cord-010398-5wot7tix 110 11 underlying underlying JJ cord-010398-5wot7tix 110 12 mechanisms mechanism NNS cord-010398-5wot7tix 110 13 that that WDT cord-010398-5wot7tix 110 14 have have VBP cord-010398-5wot7tix 110 15 been be VBN cord-010398-5wot7tix 110 16 identified identify VBN cord-010398-5wot7tix 110 17 in in IN cord-010398-5wot7tix 110 18 these these DT cord-010398-5wot7tix 110 19 illnesses illness NNS cord-010398-5wot7tix 110 20 include include VBP cord-010398-5wot7tix 110 21 : : : cord-010398-5wot7tix 110 22 ( ( -LRB- cord-010398-5wot7tix 110 23 1 1 LS cord-010398-5wot7tix 110 24 ) ) -RRB- cord-010398-5wot7tix 110 25 neurogenic neurogenic JJ cord-010398-5wot7tix 110 26 inflammation inflammation NN cord-010398-5wot7tix 110 27 , , , cord-010398-5wot7tix 110 28 especially especially RB cord-010398-5wot7tix 110 29 of of IN cord-010398-5wot7tix 110 30 mucosal mucosal JJ cord-010398-5wot7tix 110 31 surfaces surface NNS cord-010398-5wot7tix 110 32 , , , cord-010398-5wot7tix 110 33 leading lead VBG cord-010398-5wot7tix 110 34 to to IN cord-010398-5wot7tix 110 35 increased increase VBN cord-010398-5wot7tix 110 36 mast mast NN cord-010398-5wot7tix 110 37 cells cell NNS cord-010398-5wot7tix 110 38 and and CC cord-010398-5wot7tix 110 39 the the DT cord-010398-5wot7tix 110 40 appearance appearance NN cord-010398-5wot7tix 110 41 of of IN cord-010398-5wot7tix 110 42 a a DT cord-010398-5wot7tix 110 43 mild mild JJ cord-010398-5wot7tix 110 44 inflammatory inflammatory JJ cord-010398-5wot7tix 110 45 process process NN cord-010398-5wot7tix 110 46 in in IN cord-010398-5wot7tix 110 47 the the DT cord-010398-5wot7tix 110 48 periphery periphery NN cord-010398-5wot7tix 110 49 ; ; : cord-010398-5wot7tix 110 50 ( ( -LRB- cord-010398-5wot7tix 110 51 2 2 LS cord-010398-5wot7tix 110 52 ) ) -RRB- cord-010398-5wot7tix 110 53 autonomic autonomic JJ cord-010398-5wot7tix 110 54 nervous nervous JJ cord-010398-5wot7tix 110 55 system system NN cord-010398-5wot7tix 110 56 dysfunction dysfunction NN cord-010398-5wot7tix 110 57 ; ; : cord-010398-5wot7tix 110 58 and and CC cord-010398-5wot7tix 110 59 ( ( -LRB- cord-010398-5wot7tix 110 60 3 3 LS cord-010398-5wot7tix 110 61 ) ) -RRB- cord-010398-5wot7tix 110 62 hypothalamic hypothalamic JJ cord-010398-5wot7tix 110 63 pituitary pituitary NN cord-010398-5wot7tix 110 64 dysfunction dysfunction NN cord-010398-5wot7tix 110 65 . . . cord-010398-5wot7tix 111 1 • • NNP cord-010398-5wot7tix 112 1 Similar similar JJ cord-010398-5wot7tix 112 2 types type NNS cord-010398-5wot7tix 112 3 of of IN cord-010398-5wot7tix 112 4 therapies therapy NNS cord-010398-5wot7tix 112 5 are be VBP cord-010398-5wot7tix 112 6 efficacious efficacious JJ cord-010398-5wot7tix 112 7 for for IN cord-010398-5wot7tix 112 8 all all DT cord-010398-5wot7tix 112 9 of of IN cord-010398-5wot7tix 112 10 these these DT cord-010398-5wot7tix 112 11 conditions condition NNS cord-010398-5wot7tix 112 12 , , , cord-010398-5wot7tix 112 13 including include VBG cord-010398-5wot7tix 112 14 both both CC cord-010398-5wot7tix 112 15 pharmacological pharmacological JJ cord-010398-5wot7tix 112 16 ( ( -LRB- cord-010398-5wot7tix 112 17 eg eg IN cord-010398-5wot7tix 112 18 , , , cord-010398-5wot7tix 112 19 tricyclic tricyclic NN cord-010398-5wot7tix 112 20 compounds compound NNS cord-010398-5wot7tix 112 21 such such JJ cord-010398-5wot7tix 112 22 as as IN cord-010398-5wot7tix 112 23 amitriptyline amitriptyline NN cord-010398-5wot7tix 112 24 ) ) -RRB- cord-010398-5wot7tix 112 25 and and CC cord-010398-5wot7tix 112 26 nonpharmacological nonpharmacological JJ cord-010398-5wot7tix 112 27 treatments treatment NNS cord-010398-5wot7tix 112 28 ( ( -LRB- cord-010398-5wot7tix 112 29 eg eg RB cord-010398-5wot7tix 112 30 , , , cord-010398-5wot7tix 112 31 exercise exercise NN cord-010398-5wot7tix 112 32 and and CC cord-010398-5wot7tix 112 33 cognitive cognitive JJ cord-010398-5wot7tix 112 34 behavioral behavioral JJ cord-010398-5wot7tix 112 35 therapy therapy NN cord-010398-5wot7tix 112 36 [ [ -LRB- cord-010398-5wot7tix 112 37 CBT CBT NNP cord-010398-5wot7tix 112 38 ] ] -RRB- cord-010398-5wot7tix 112 39 ) ) -RRB- cord-010398-5wot7tix 112 40 . . . cord-010398-5wot7tix 113 1 Conversely conversely RB cord-010398-5wot7tix 113 2 , , , cord-010398-5wot7tix 113 3 patients patient NNS cord-010398-5wot7tix 113 4 with with IN cord-010398-5wot7tix 113 5 these these DT cord-010398-5wot7tix 113 6 conditions condition NNS cord-010398-5wot7tix 113 7 typically typically RB cord-010398-5wot7tix 113 8 do do VBP cord-010398-5wot7tix 113 9 not not RB cord-010398-5wot7tix 113 10 respond respond VB cord-010398-5wot7tix 113 11 to to IN cord-010398-5wot7tix 113 12 therapies therapy NNS cord-010398-5wot7tix 113 13 that that WDT cord-010398-5wot7tix 113 14 are be VBP cord-010398-5wot7tix 113 15 effective effective JJ cord-010398-5wot7tix 113 16 when when WRB cord-010398-5wot7tix 113 17 pain pain NN cord-010398-5wot7tix 113 18 is be VBZ cord-010398-5wot7tix 113 19 attributable attributable JJ cord-010398-5wot7tix 113 20 to to IN cord-010398-5wot7tix 113 21 damage damage NN cord-010398-5wot7tix 113 22 or or CC cord-010398-5wot7tix 113 23 inflammation inflammation NN cord-010398-5wot7tix 113 24 of of IN cord-010398-5wot7tix 113 25 tissues tissue NNS cord-010398-5wot7tix 113 26 ( ( -LRB- cord-010398-5wot7tix 113 27 eg eg RB cord-010398-5wot7tix 113 28 , , , cord-010398-5wot7tix 113 29 nonsteroidal nonsteroidal JJ cord-010398-5wot7tix 113 30 antiinflammatory antiinflammatory JJ cord-010398-5wot7tix 113 31 drugs drug NNS cord-010398-5wot7tix 113 32 , , , cord-010398-5wot7tix 113 33 opioids opioid NNS cord-010398-5wot7tix 113 34 , , , cord-010398-5wot7tix 113 35 injections injection NNS cord-010398-5wot7tix 113 36 , , , cord-010398-5wot7tix 113 37 surgical surgical JJ cord-010398-5wot7tix 113 38 procedures procedure NNS cord-010398-5wot7tix 113 39 ) ) -RRB- cord-010398-5wot7tix 113 40 . . . cord-010398-5wot7tix 114 1 The the DT cord-010398-5wot7tix 114 2 aforementioned aforementioned JJ cord-010398-5wot7tix 114 3 list list NN cord-010398-5wot7tix 114 4 is be VBZ cord-010398-5wot7tix 114 5 meant mean VBN cord-010398-5wot7tix 114 6 to to TO cord-010398-5wot7tix 114 7 be be VB cord-010398-5wot7tix 114 8 a a DT cord-010398-5wot7tix 114 9 summary summary NN cord-010398-5wot7tix 114 10 of of IN cord-010398-5wot7tix 114 11 the the DT cord-010398-5wot7tix 114 12 findings finding NNS cord-010398-5wot7tix 114 13 across across IN cord-010398-5wot7tix 114 14 the the DT cord-010398-5wot7tix 114 15 functional functional JJ cord-010398-5wot7tix 114 16 somatic somatic JJ cord-010398-5wot7tix 114 17 or or CC cord-010398-5wot7tix 114 18 central central JJ cord-010398-5wot7tix 114 19 sensitivity sensitivity NN cord-010398-5wot7tix 114 20 field field NN cord-010398-5wot7tix 114 21 . . . cord-010398-5wot7tix 115 1 CFS CFS NNP cord-010398-5wot7tix 115 2 is be VBZ cord-010398-5wot7tix 115 3 a a DT cord-010398-5wot7tix 115 4 heterogeneous heterogeneous JJ cord-010398-5wot7tix 115 5 disorder disorder NN cord-010398-5wot7tix 115 6 and and CC cord-010398-5wot7tix 115 7 likely likely JJ cord-010398-5wot7tix 115 8 includes include VBZ cord-010398-5wot7tix 115 9 patients patient NNS cord-010398-5wot7tix 115 10 who who WP cord-010398-5wot7tix 115 11 have have VBP cord-010398-5wot7tix 115 12 entirely entirely RB cord-010398-5wot7tix 115 13 different different JJ cord-010398-5wot7tix 115 14 pathophysiology pathophysiology NN cord-010398-5wot7tix 115 15 , , , cord-010398-5wot7tix 115 16 such such JJ cord-010398-5wot7tix 115 17 as as IN cord-010398-5wot7tix 115 18 those those DT cord-010398-5wot7tix 115 19 who who WP cord-010398-5wot7tix 115 20 have have VBP cord-010398-5wot7tix 115 21 an an DT cord-010398-5wot7tix 115 22 infectious infectious JJ cord-010398-5wot7tix 115 23 or or CC cord-010398-5wot7tix 115 24 metabolic metabolic JJ cord-010398-5wot7tix 115 25 condition condition NN cord-010398-5wot7tix 115 26 that that WDT cord-010398-5wot7tix 115 27 has have VBZ cord-010398-5wot7tix 115 28 yet yet RB cord-010398-5wot7tix 115 29 to to TO cord-010398-5wot7tix 115 30 be be VB cord-010398-5wot7tix 115 31 identified identify VBN cord-010398-5wot7tix 115 32 . . . cord-010398-5wot7tix 116 1 Some some DT cord-010398-5wot7tix 116 2 patients patient NNS cord-010398-5wot7tix 116 3 who who WP cord-010398-5wot7tix 116 4 meet meet VBP cord-010398-5wot7tix 116 5 criteria criterion NNS cord-010398-5wot7tix 116 6 for for IN cord-010398-5wot7tix 116 7 CFS CFS NNP cord-010398-5wot7tix 116 8 may may MD cord-010398-5wot7tix 116 9 not not RB cord-010398-5wot7tix 116 10 have have VB cord-010398-5wot7tix 116 11 this this DT cord-010398-5wot7tix 116 12 spectrum spectrum NN cord-010398-5wot7tix 116 13 of of IN cord-010398-5wot7tix 116 14 illness illness NN cord-010398-5wot7tix 116 15 as as IN cord-010398-5wot7tix 116 16 the the DT cord-010398-5wot7tix 116 17 root root NN cord-010398-5wot7tix 116 18 cause cause NN cord-010398-5wot7tix 116 19 for for IN cord-010398-5wot7tix 116 20 their -PRON- PRP$ cord-010398-5wot7tix 116 21 symptoms symptom NNS cord-010398-5wot7tix 116 22 . . . cord-010398-5wot7tix 117 1 Cognitive cognitive JJ cord-010398-5wot7tix 117 2 difficulties difficulty NNS cord-010398-5wot7tix 117 3 have have VBP cord-010398-5wot7tix 117 4 been be VBN cord-010398-5wot7tix 117 5 particularly particularly RB cord-010398-5wot7tix 117 6 well well RB cord-010398-5wot7tix 117 7 - - HYPH cord-010398-5wot7tix 117 8 studied study VBN cord-010398-5wot7tix 117 9 in in IN cord-010398-5wot7tix 117 10 CFS CFS NNP cord-010398-5wot7tix 117 11 . . . cord-010398-5wot7tix 118 1 The the DT cord-010398-5wot7tix 118 2 authors author NNS cord-010398-5wot7tix 118 3 of of IN cord-010398-5wot7tix 118 4 CFS CFS NNP cord-010398-5wot7tix 118 5 studies study NNS cord-010398-5wot7tix 118 6 have have VBP cord-010398-5wot7tix 118 7 suggested suggest VBN cord-010398-5wot7tix 118 8 that that IN cord-010398-5wot7tix 118 9 memory memory NN cord-010398-5wot7tix 118 10 problems problem NNS cord-010398-5wot7tix 118 11 are be VBP cord-010398-5wot7tix 118 12 a a DT cord-010398-5wot7tix 118 13 common common JJ cord-010398-5wot7tix 118 14 complaint complaint NN cord-010398-5wot7tix 118 15 , , , cord-010398-5wot7tix 118 16 but but CC cord-010398-5wot7tix 118 17 some some DT cord-010398-5wot7tix 118 18 authors author NNS cord-010398-5wot7tix 118 19 suggest suggest VBP cord-010398-5wot7tix 118 20 that that IN cord-010398-5wot7tix 118 21 these these DT cord-010398-5wot7tix 118 22 subjective subjective JJ cord-010398-5wot7tix 118 23 symptoms symptom NNS cord-010398-5wot7tix 118 24 are be VBP cord-010398-5wot7tix 118 25 accompanied accompany VBN cord-010398-5wot7tix 118 26 by by IN cord-010398-5wot7tix 118 27 objective objective JJ cord-010398-5wot7tix 118 28 abnormalities abnormality NNS cord-010398-5wot7tix 118 29 on on IN cord-010398-5wot7tix 118 30 neuropsychological neuropsychological JJ cord-010398-5wot7tix 118 31 testing testing NN cord-010398-5wot7tix 118 32 . . . cord-010398-5wot7tix 119 1 However however RB cord-010398-5wot7tix 119 2 , , , cord-010398-5wot7tix 119 3 most most JJS cord-010398-5wot7tix 119 4 did do VBD cord-010398-5wot7tix 119 5 not not RB cord-010398-5wot7tix 119 6 find find VB cord-010398-5wot7tix 119 7 good good JJ cord-010398-5wot7tix 119 8 correlation correlation NN cord-010398-5wot7tix 119 9 between between IN cord-010398-5wot7tix 119 10 objective objective JJ cord-010398-5wot7tix 119 11 neuropsychological neuropsychological JJ cord-010398-5wot7tix 119 12 findings finding NNS cord-010398-5wot7tix 119 13 or or CC cord-010398-5wot7tix 119 14 biological biological JJ cord-010398-5wot7tix 119 15 markers marker NNS cord-010398-5wot7tix 119 16 , , , cord-010398-5wot7tix 119 17 and and CC cord-010398-5wot7tix 119 18 symptoms symptom NNS cord-010398-5wot7tix 119 19 of of IN cord-010398-5wot7tix 119 20 dyscognition dyscognition NN cord-010398-5wot7tix 119 21 [ [ -LRB- cord-010398-5wot7tix 119 22 44 44 CD cord-010398-5wot7tix 119 23 ] ] -RRB- cord-010398-5wot7tix 119 24 [ [ -LRB- cord-010398-5wot7tix 119 25 45 45 CD cord-010398-5wot7tix 119 26 ] ] -RRB- cord-010398-5wot7tix 120 1 [ [ -LRB- cord-010398-5wot7tix 120 2 46 46 CD cord-010398-5wot7tix 120 3 ] ] -RRB- cord-010398-5wot7tix 120 4 [ [ -LRB- cord-010398-5wot7tix 120 5 47 47 CD cord-010398-5wot7tix 120 6 ] ] -RRB- cord-010398-5wot7tix 120 7 [ [ -LRB- cord-010398-5wot7tix 120 8 48 48 CD cord-010398-5wot7tix 120 9 ] ] -RRB- cord-010398-5wot7tix 120 10 . . . cord-010398-5wot7tix 121 1 Some some DT cord-010398-5wot7tix 121 2 of of IN cord-010398-5wot7tix 121 3 this this DT cord-010398-5wot7tix 121 4 disparity disparity NN cord-010398-5wot7tix 121 5 likely likely RB cord-010398-5wot7tix 121 6 occurred occur VBD cord-010398-5wot7tix 121 7 because because IN cord-010398-5wot7tix 121 8 the the DT cord-010398-5wot7tix 121 9 early early JJ cord-010398-5wot7tix 121 10 testing testing NN cord-010398-5wot7tix 121 11 paradigms paradigm NNS cord-010398-5wot7tix 121 12 did do VBD cord-010398-5wot7tix 121 13 not not RB cord-010398-5wot7tix 121 14 focus focus VB cord-010398-5wot7tix 121 15 on on IN cord-010398-5wot7tix 121 16 areas area NNS cord-010398-5wot7tix 121 17 that that WDT cord-010398-5wot7tix 121 18 were be VBD cord-010398-5wot7tix 121 19 subsequently subsequently RB cord-010398-5wot7tix 121 20 shown show VBN cord-010398-5wot7tix 121 21 to to TO cord-010398-5wot7tix 121 22 be be VB cord-010398-5wot7tix 121 23 most most RBS cord-010398-5wot7tix 121 24 abnormal abnormal JJ cord-010398-5wot7tix 121 25 in in IN cord-010398-5wot7tix 121 26 CFS CFS NNP cord-010398-5wot7tix 121 27 , , , cord-010398-5wot7tix 121 28 such such JJ cord-010398-5wot7tix 121 29 as as IN cord-010398-5wot7tix 121 30 information information NN cord-010398-5wot7tix 121 31 processing processing NN cord-010398-5wot7tix 121 32 speed speed NN cord-010398-5wot7tix 121 33 , , , cord-010398-5wot7tix 121 34 motor motor NN cord-010398-5wot7tix 121 35 speed speed NN cord-010398-5wot7tix 121 36 , , , cord-010398-5wot7tix 121 37 working working NN cord-010398-5wot7tix 121 38 memory memory NN cord-010398-5wot7tix 121 39 , , , cord-010398-5wot7tix 121 40 and and CC cord-010398-5wot7tix 121 41 simple simple JJ cord-010398-5wot7tix 121 42 and and CC cord-010398-5wot7tix 121 43 complex complex JJ cord-010398-5wot7tix 121 44 attentional attentional JJ cord-010398-5wot7tix 121 45 tasks task NNS cord-010398-5wot7tix 121 46 [ [ -LRB- cord-010398-5wot7tix 121 47 49 49 CD cord-010398-5wot7tix 121 48 ] ] -RRB- cord-010398-5wot7tix 121 49 . . . cord-010398-5wot7tix 122 1 In in IN cord-010398-5wot7tix 122 2 more more JJR cord-010398-5wot7tix 122 3 recent recent JJ cord-010398-5wot7tix 122 4 studies study NNS cord-010398-5wot7tix 122 5 [ [ -LRB- cord-010398-5wot7tix 122 6 50 50 CD cord-010398-5wot7tix 122 7 ] ] -RRB- cord-010398-5wot7tix 122 8 [ [ -LRB- cord-010398-5wot7tix 122 9 51 51 CD cord-010398-5wot7tix 122 10 ] ] -RRB- cord-010398-5wot7tix 122 11 [ [ -LRB- cord-010398-5wot7tix 122 12 52 52 CD cord-010398-5wot7tix 122 13 ] ] -RRB- cord-010398-5wot7tix 122 14 [ [ -LRB- cord-010398-5wot7tix 122 15 53 53 CD cord-010398-5wot7tix 122 16 ] ] -RRB- cord-010398-5wot7tix 122 17 , , , cord-010398-5wot7tix 122 18 authors author NNS cord-010398-5wot7tix 122 19 have have VBP cord-010398-5wot7tix 122 20 used use VBN cord-010398-5wot7tix 122 21 neuropsychological neuropsychological JJ cord-010398-5wot7tix 122 22 batteries battery NNS cord-010398-5wot7tix 122 23 tailored tailor VBN cord-010398-5wot7tix 122 24 to to IN cord-010398-5wot7tix 122 25 the the DT cord-010398-5wot7tix 122 26 domains domain NNS cord-010398-5wot7tix 122 27 that that WDT cord-010398-5wot7tix 122 28 appear appear VBP cord-010398-5wot7tix 122 29 to to TO cord-010398-5wot7tix 122 30 be be VB cord-010398-5wot7tix 122 31 most most RBS cord-010398-5wot7tix 122 32 impaired impaired JJ cord-010398-5wot7tix 122 33 . . . cord-010398-5wot7tix 123 1 These these DT cord-010398-5wot7tix 123 2 authors author NNS cord-010398-5wot7tix 123 3 typically typically RB cord-010398-5wot7tix 123 4 identified identify VBD cord-010398-5wot7tix 123 5 group group NN cord-010398-5wot7tix 123 6 differences difference NNS cord-010398-5wot7tix 123 7 between between IN cord-010398-5wot7tix 123 8 CFS cfs NN cord-010398-5wot7tix 123 9 and and CC cord-010398-5wot7tix 123 10 control control NN cord-010398-5wot7tix 123 11 patients patient NNS cord-010398-5wot7tix 123 12 . . . cord-010398-5wot7tix 124 1 These these DT cord-010398-5wot7tix 124 2 effects effect NNS cord-010398-5wot7tix 124 3 were be VBD cord-010398-5wot7tix 124 4 independent independent JJ cord-010398-5wot7tix 124 5 of of IN cord-010398-5wot7tix 124 6 and and CC cord-010398-5wot7tix 124 7 could could MD cord-010398-5wot7tix 124 8 be be VB cord-010398-5wot7tix 124 9 differentiated differentiate VBN cord-010398-5wot7tix 124 10 from from IN cord-010398-5wot7tix 124 11 effects effect NNS cord-010398-5wot7tix 124 12 found find VBN cord-010398-5wot7tix 124 13 in in IN cord-010398-5wot7tix 124 14 frequently frequently RB cord-010398-5wot7tix 124 15 comorbid comorbid VBN cord-010398-5wot7tix 124 16 disorders disorder NNS cord-010398-5wot7tix 124 17 , , , cord-010398-5wot7tix 124 18 such such JJ cord-010398-5wot7tix 124 19 as as IN cord-010398-5wot7tix 124 20 depression depression NN cord-010398-5wot7tix 124 21 , , , cord-010398-5wot7tix 124 22 where where WRB cord-010398-5wot7tix 124 23 there there EX cord-010398-5wot7tix 124 24 is be VBZ cord-010398-5wot7tix 124 25 greater great JJR cord-010398-5wot7tix 124 26 psychomotor psychomotor NN cord-010398-5wot7tix 124 27 slowing slow VBG cord-010398-5wot7tix 124 28 . . . cord-010398-5wot7tix 125 1 There there EX cord-010398-5wot7tix 125 2 is be VBZ cord-010398-5wot7tix 125 3 a a DT cord-010398-5wot7tix 125 4 considerable considerable JJ cord-010398-5wot7tix 125 5 disparity disparity NN cord-010398-5wot7tix 125 6 between between IN cord-010398-5wot7tix 125 7 any any DT cord-010398-5wot7tix 125 8 patient patient NN cord-010398-5wot7tix 125 9 's 's POS cord-010398-5wot7tix 125 10 self self NN cord-010398-5wot7tix 125 11 - - HYPH cord-010398-5wot7tix 125 12 assessment assessment NN cord-010398-5wot7tix 125 13 of of IN cord-010398-5wot7tix 125 14 his -PRON- PRP$ cord-010398-5wot7tix 125 15 or or CC cord-010398-5wot7tix 125 16 her -PRON- PRP$ cord-010398-5wot7tix 125 17 cognitive cognitive JJ cord-010398-5wot7tix 125 18 function function NN cord-010398-5wot7tix 125 19 and and CC cord-010398-5wot7tix 125 20 the the DT cord-010398-5wot7tix 125 21 actual actual JJ cord-010398-5wot7tix 125 22 cognitive cognitive JJ cord-010398-5wot7tix 125 23 function function NN cord-010398-5wot7tix 125 24 as as IN cord-010398-5wot7tix 125 25 measured measure VBN cord-010398-5wot7tix 125 26 by by IN cord-010398-5wot7tix 125 27 neuropsychological neuropsychological JJ cord-010398-5wot7tix 125 28 batteries battery NNS cord-010398-5wot7tix 125 29 in in IN cord-010398-5wot7tix 125 30 patients patient NNS cord-010398-5wot7tix 125 31 with with IN cord-010398-5wot7tix 125 32 and and CC cord-010398-5wot7tix 125 33 without without IN cord-010398-5wot7tix 125 34 disease disease NN cord-010398-5wot7tix 125 35 . . . cord-010398-5wot7tix 126 1 The the DT cord-010398-5wot7tix 126 2 interest interest NN cord-010398-5wot7tix 126 3 in in IN cord-010398-5wot7tix 126 4 possible possible JJ cord-010398-5wot7tix 126 5 brain brain NN cord-010398-5wot7tix 126 6 dysfunction dysfunction NN cord-010398-5wot7tix 126 7 in in IN cord-010398-5wot7tix 126 8 CFS CFS NNP cord-010398-5wot7tix 126 9 also also RB cord-010398-5wot7tix 126 10 led lead VBD cord-010398-5wot7tix 126 11 to to IN cord-010398-5wot7tix 126 12 a a DT cord-010398-5wot7tix 126 13 flurry flurry NN cord-010398-5wot7tix 126 14 of of IN cord-010398-5wot7tix 126 15 structural structural JJ cord-010398-5wot7tix 126 16 imaging imaging NN cord-010398-5wot7tix 126 17 studies study NNS cord-010398-5wot7tix 126 18 in in IN cord-010398-5wot7tix 126 19 CFS CFS NNP cord-010398-5wot7tix 126 20 . . . cord-010398-5wot7tix 127 1 Many many JJ cord-010398-5wot7tix 127 2 studies study NNS cord-010398-5wot7tix 127 3 showed show VBD cord-010398-5wot7tix 127 4 abnormalities abnormality NNS cord-010398-5wot7tix 127 5 in in IN cord-010398-5wot7tix 127 6 the the DT cord-010398-5wot7tix 127 7 white white JJ cord-010398-5wot7tix 127 8 matter matter NN cord-010398-5wot7tix 127 9 on on IN cord-010398-5wot7tix 127 10 structural structural JJ cord-010398-5wot7tix 127 11 magnetic magnetic JJ cord-010398-5wot7tix 127 12 resonance resonance NN cord-010398-5wot7tix 127 13 imaging imaging NN cord-010398-5wot7tix 127 14 scans scan NNS cord-010398-5wot7tix 127 15 , , , cord-010398-5wot7tix 127 16 but but CC cord-010398-5wot7tix 127 17 the the DT cord-010398-5wot7tix 127 18 authors author NNS cord-010398-5wot7tix 127 19 of of IN cord-010398-5wot7tix 127 20 several several JJ cord-010398-5wot7tix 127 21 wellcontrolled wellcontrolled JJ cord-010398-5wot7tix 127 22 studies study NNS cord-010398-5wot7tix 127 23 [ [ -LRB- cord-010398-5wot7tix 127 24 54 54 CD cord-010398-5wot7tix 127 25 ] ] -RRB- cord-010398-5wot7tix 127 26 [ [ -LRB- cord-010398-5wot7tix 127 27 55 55 CD cord-010398-5wot7tix 127 28 ] ] -RRB- cord-010398-5wot7tix 127 29 [ [ -LRB- cord-010398-5wot7tix 127 30 56 56 CD cord-010398-5wot7tix 127 31 ] ] -RRB- cord-010398-5wot7tix 127 32 [ [ -LRB- cord-010398-5wot7tix 127 33 57 57 CD cord-010398-5wot7tix 127 34 ] ] -RRB- cord-010398-5wot7tix 127 35 [ [ -LRB- cord-010398-5wot7tix 127 36 58 58 CD cord-010398-5wot7tix 127 37 ] ] -RRB- cord-010398-5wot7tix 127 38 failed fail VBD cord-010398-5wot7tix 127 39 to to TO cord-010398-5wot7tix 127 40 replicate replicate VB cord-010398-5wot7tix 127 41 these these DT cord-010398-5wot7tix 127 42 findings finding NNS cord-010398-5wot7tix 127 43 , , , cord-010398-5wot7tix 127 44 and and CC cord-010398-5wot7tix 127 45 none none NN cord-010398-5wot7tix 127 46 of of IN cord-010398-5wot7tix 127 47 the the DT cord-010398-5wot7tix 127 48 findings finding NNS cord-010398-5wot7tix 127 49 on on IN cord-010398-5wot7tix 127 50 magnetic magnetic JJ cord-010398-5wot7tix 127 51 resonance resonance NN cord-010398-5wot7tix 127 52 imaging imaging NN cord-010398-5wot7tix 127 53 were be VBD cord-010398-5wot7tix 127 54 ever ever RB cord-010398-5wot7tix 127 55 found find VBN cord-010398-5wot7tix 127 56 to to TO cord-010398-5wot7tix 127 57 be be VB cord-010398-5wot7tix 127 58 sensitive sensitive JJ cord-010398-5wot7tix 127 59 or or CC cord-010398-5wot7tix 127 60 specific specific JJ cord-010398-5wot7tix 127 61 for for IN cord-010398-5wot7tix 127 62 CFS CFS NNP cord-010398-5wot7tix 127 63 . . . cord-010398-5wot7tix 128 1 A a DT cord-010398-5wot7tix 128 2 newer new JJR cord-010398-5wot7tix 128 3 method method NN cord-010398-5wot7tix 128 4 of of IN cord-010398-5wot7tix 128 5 assessing assess VBG cord-010398-5wot7tix 128 6 brain brain NN cord-010398-5wot7tix 128 7 volumes volume NNS cord-010398-5wot7tix 128 8 has have VBZ cord-010398-5wot7tix 128 9 gained gain VBN cord-010398-5wot7tix 128 10 widespread widespread JJ cord-010398-5wot7tix 128 11 use use NN cord-010398-5wot7tix 128 12 in in IN cord-010398-5wot7tix 128 13 neuroscience neuroscience NN cord-010398-5wot7tix 128 14 and and CC cord-010398-5wot7tix 128 15 chronic chronic JJ cord-010398-5wot7tix 128 16 pain pain NN cord-010398-5wot7tix 128 17 states state NNS cord-010398-5wot7tix 128 18 and and CC cord-010398-5wot7tix 128 19 is be VBZ cord-010398-5wot7tix 128 20 just just RB cord-010398-5wot7tix 128 21 beginning begin VBG cord-010398-5wot7tix 128 22 to to TO cord-010398-5wot7tix 128 23 be be VB cord-010398-5wot7tix 128 24 applied apply VBN cord-010398-5wot7tix 128 25 to to IN cord-010398-5wot7tix 128 26 CFS CFS NNP cord-010398-5wot7tix 128 27 . . . cord-010398-5wot7tix 129 1 The the DT cord-010398-5wot7tix 129 2 authors author NNS cord-010398-5wot7tix 129 3 of of IN cord-010398-5wot7tix 129 4 a a DT cord-010398-5wot7tix 129 5 recent recent JJ cord-010398-5wot7tix 129 6 study study NN cord-010398-5wot7tix 129 7 [ [ -LRB- cord-010398-5wot7tix 129 8 59 59 CD cord-010398-5wot7tix 129 9 ] ] -RRB- cord-010398-5wot7tix 129 10 have have VBP cord-010398-5wot7tix 129 11 suggested suggest VBN cord-010398-5wot7tix 129 12 that that IN cord-010398-5wot7tix 129 13 improvements improvement NNS cord-010398-5wot7tix 129 14 after after IN cord-010398-5wot7tix 129 15 CBT CBT NNP cord-010398-5wot7tix 129 16 were be VBD cord-010398-5wot7tix 129 17 accompanied accompany VBN cord-010398-5wot7tix 129 18 by by IN cord-010398-5wot7tix 129 19 increases increase NNS cord-010398-5wot7tix 129 20 in in IN cord-010398-5wot7tix 129 21 brain brain NN cord-010398-5wot7tix 129 22 volume volume NN cord-010398-5wot7tix 129 23 . . . cord-010398-5wot7tix 130 1 By by IN cord-010398-5wot7tix 130 2 the the DT cord-010398-5wot7tix 130 3 use use NN cord-010398-5wot7tix 130 4 of of IN cord-010398-5wot7tix 130 5 functional functional JJ cord-010398-5wot7tix 130 6 neuroimaging neuroimaging NN cord-010398-5wot7tix 130 7 studies study NNS cord-010398-5wot7tix 130 8 , , , cord-010398-5wot7tix 130 9 researchers researcher NNS cord-010398-5wot7tix 130 10 [ [ -LRB- cord-010398-5wot7tix 130 11 60 60 CD cord-010398-5wot7tix 130 12 ] ] -RRB- cord-010398-5wot7tix 130 13 also also RB cord-010398-5wot7tix 130 14 have have VBP cord-010398-5wot7tix 130 15 examined examine VBN cord-010398-5wot7tix 130 16 changes change NNS cord-010398-5wot7tix 130 17 in in IN cord-010398-5wot7tix 130 18 blood blood NN cord-010398-5wot7tix 130 19 flow flow NN cord-010398-5wot7tix 130 20 with with IN cord-010398-5wot7tix 130 21 activity activity NN cord-010398-5wot7tix 130 22 - - HYPH cord-010398-5wot7tix 130 23 related relate VBN cord-010398-5wot7tix 130 24 tasks task NNS cord-010398-5wot7tix 130 25 , , , cord-010398-5wot7tix 130 26 and and CC cord-010398-5wot7tix 130 27 in in IN cord-010398-5wot7tix 130 28 CFS CFS NNP cord-010398-5wot7tix 130 29 the the DT cord-010398-5wot7tix 130 30 provocation provocation NN cord-010398-5wot7tix 130 31 of of IN cord-010398-5wot7tix 130 32 fatigue fatigue NN cord-010398-5wot7tix 130 33 has have VBZ cord-010398-5wot7tix 130 34 been be VBN cord-010398-5wot7tix 130 35 associated associate VBN cord-010398-5wot7tix 130 36 with with IN cord-010398-5wot7tix 130 37 emotional emotional JJ cord-010398-5wot7tix 130 38 responses response NNS cord-010398-5wot7tix 130 39 that that WDT cord-010398-5wot7tix 130 40 patients patient NNS cord-010398-5wot7tix 130 41 may may MD cord-010398-5wot7tix 130 42 have have VB cord-010398-5wot7tix 130 43 difficulty difficulty NN cord-010398-5wot7tix 130 44 suppressing suppress VBG cord-010398-5wot7tix 130 45 . . . cord-010398-5wot7tix 131 1 Sleep sleep NN cord-010398-5wot7tix 131 2 has have VBZ cord-010398-5wot7tix 131 3 also also RB cord-010398-5wot7tix 131 4 been be VBN cord-010398-5wot7tix 131 5 well well RB cord-010398-5wot7tix 131 6 - - HYPH cord-010398-5wot7tix 131 7 studied study VBN cord-010398-5wot7tix 131 8 in in IN cord-010398-5wot7tix 131 9 CFS CFS NNP cord-010398-5wot7tix 131 10 because because IN cord-010398-5wot7tix 131 11 a a DT cord-010398-5wot7tix 131 12 logical logical JJ cord-010398-5wot7tix 131 13 conclusion conclusion NN cord-010398-5wot7tix 131 14 might may MD cord-010398-5wot7tix 131 15 be be VB cord-010398-5wot7tix 131 16 that that DT cord-010398-5wot7tix 131 17 chronic chronic JJ cord-010398-5wot7tix 131 18 sleep sleep NN cord-010398-5wot7tix 131 19 deprivation deprivation NN cord-010398-5wot7tix 131 20 leads lead VBZ cord-010398-5wot7tix 131 21 to to IN cord-010398-5wot7tix 131 22 fatigue fatigue NN cord-010398-5wot7tix 131 23 and and CC cord-010398-5wot7tix 131 24 other other JJ cord-010398-5wot7tix 131 25 comorbid comorbid NN cord-010398-5wot7tix 131 26 symptoms symptom NNS cord-010398-5wot7tix 131 27 found find VBN cord-010398-5wot7tix 131 28 in in IN cord-010398-5wot7tix 131 29 CFS cfs NN cord-010398-5wot7tix 131 30 patients patient NNS cord-010398-5wot7tix 131 31 [ [ -LRB- cord-010398-5wot7tix 131 32 61 61 CD cord-010398-5wot7tix 131 33 ] ] -RRB- cord-010398-5wot7tix 132 1 [ [ -LRB- cord-010398-5wot7tix 132 2 62 62 CD cord-010398-5wot7tix 132 3 ] ] -RRB- cord-010398-5wot7tix 132 4 [ [ -LRB- cord-010398-5wot7tix 132 5 63 63 CD cord-010398-5wot7tix 132 6 ] ] -RRB- cord-010398-5wot7tix 132 7 . . . cord-010398-5wot7tix 133 1 Many many JJ cord-010398-5wot7tix 133 2 sleep sleep NN cord-010398-5wot7tix 133 3 abnormalities abnormality NNS cord-010398-5wot7tix 133 4 were be VBD cord-010398-5wot7tix 133 5 noted note VBN cord-010398-5wot7tix 133 6 in in IN cord-010398-5wot7tix 133 7 a a DT cord-010398-5wot7tix 133 8 series series NN cord-010398-5wot7tix 133 9 of of IN cord-010398-5wot7tix 133 10 studies study NNS cord-010398-5wot7tix 133 11 of of IN cord-010398-5wot7tix 133 12 CFS cfs NN cord-010398-5wot7tix 133 13 patients patient NNS cord-010398-5wot7tix 133 14 , , , cord-010398-5wot7tix 133 15 but but CC cord-010398-5wot7tix 133 16 similar similar JJ cord-010398-5wot7tix 133 17 to to IN cord-010398-5wot7tix 133 18 findings finding NNS cord-010398-5wot7tix 133 19 in in IN cord-010398-5wot7tix 133 20 sleep sleep NN cord-010398-5wot7tix 133 21 studies study NNS cord-010398-5wot7tix 133 22 of of IN cord-010398-5wot7tix 133 23 FM FM NNP cord-010398-5wot7tix 133 24 patients patient NNS cord-010398-5wot7tix 133 25 , , , cord-010398-5wot7tix 133 26 none none NN cord-010398-5wot7tix 133 27 of of IN cord-010398-5wot7tix 133 28 these these DT cord-010398-5wot7tix 133 29 findings finding NNS cord-010398-5wot7tix 133 30 was be VBD cord-010398-5wot7tix 133 31 found find VBN cord-010398-5wot7tix 133 32 to to TO cord-010398-5wot7tix 133 33 be be VB cord-010398-5wot7tix 133 34 sensitive sensitive JJ cord-010398-5wot7tix 133 35 or or CC cord-010398-5wot7tix 133 36 specific specific JJ cord-010398-5wot7tix 133 37 for for IN cord-010398-5wot7tix 133 38 FM FM NNP cord-010398-5wot7tix 133 39 or or CC cord-010398-5wot7tix 133 40 CFS CFS NNP cord-010398-5wot7tix 133 41 [ [ -LRB- cord-010398-5wot7tix 133 42 64 64 CD cord-010398-5wot7tix 133 43 ] ] -RRB- cord-010398-5wot7tix 133 44 . . . cord-010398-5wot7tix 134 1 Nonetheless nonetheless RB cord-010398-5wot7tix 134 2 , , , cord-010398-5wot7tix 134 3 it -PRON- PRP cord-010398-5wot7tix 134 4 is be VBZ cord-010398-5wot7tix 134 5 becoming become VBG cord-010398-5wot7tix 134 6 increasingly increasingly RB cord-010398-5wot7tix 134 7 clear clear JJ cord-010398-5wot7tix 134 8 that that IN cord-010398-5wot7tix 134 9 there there EX cord-010398-5wot7tix 134 10 are be VBP cord-010398-5wot7tix 134 11 very very RB cord-010398-5wot7tix 134 12 important important JJ cord-010398-5wot7tix 134 13 interrelationships interrelationship NNS cord-010398-5wot7tix 134 14 between between IN cord-010398-5wot7tix 134 15 the the DT cord-010398-5wot7tix 134 16 symptoms symptom NNS cord-010398-5wot7tix 134 17 of of IN cord-010398-5wot7tix 134 18 pain pain NN cord-010398-5wot7tix 134 19 , , , cord-010398-5wot7tix 134 20 fatigue fatigue NN cord-010398-5wot7tix 134 21 , , , cord-010398-5wot7tix 134 22 and and CC cord-010398-5wot7tix 134 23 insomnia insomnia NN cord-010398-5wot7tix 134 24 and and CC cord-010398-5wot7tix 134 25 the the DT cord-010398-5wot7tix 134 26 underlying underlying JJ cord-010398-5wot7tix 134 27 pathogenesis pathogenesis NN cord-010398-5wot7tix 134 28 of of IN cord-010398-5wot7tix 134 29 these these DT cord-010398-5wot7tix 134 30 symptoms symptom NNS cord-010398-5wot7tix 134 31 that that WDT cord-010398-5wot7tix 134 32 are be VBP cord-010398-5wot7tix 134 33 so so RB cord-010398-5wot7tix 134 34 often often RB cord-010398-5wot7tix 134 35 shared share VBN cord-010398-5wot7tix 134 36 [ [ -LRB- cord-010398-5wot7tix 134 37 64 64 CD cord-010398-5wot7tix 134 38 ] ] -RRB- cord-010398-5wot7tix 134 39 . . . cord-010398-5wot7tix 135 1 Exercise exercise NN cord-010398-5wot7tix 135 2 and and CC cord-010398-5wot7tix 135 3 activity activity NN cord-010398-5wot7tix 135 4 level level NN cord-010398-5wot7tix 135 5 are be VBP cord-010398-5wot7tix 135 6 as as RB cord-010398-5wot7tix 135 7 important important JJ cord-010398-5wot7tix 135 8 as as IN cord-010398-5wot7tix 135 9 sleep sleep NN cord-010398-5wot7tix 135 10 in in IN cord-010398-5wot7tix 135 11 CFS cfs NN cord-010398-5wot7tix 135 12 and and CC cord-010398-5wot7tix 135 13 the the DT cord-010398-5wot7tix 135 14 entire entire JJ cord-010398-5wot7tix 135 15 spectrum spectrum NN cord-010398-5wot7tix 135 16 of of IN cord-010398-5wot7tix 135 17 illness illness NN cord-010398-5wot7tix 135 18 . . . cord-010398-5wot7tix 136 1 Couch couch NN cord-010398-5wot7tix 136 2 potatoes potato NNS cord-010398-5wot7tix 136 3 rarely rarely RB cord-010398-5wot7tix 136 4 develop develop VB cord-010398-5wot7tix 136 5 CFS CFS NNP cord-010398-5wot7tix 136 6 . . . cord-010398-5wot7tix 137 1 Several several JJ cord-010398-5wot7tix 137 2 reports report NNS cord-010398-5wot7tix 137 3 document document NN cord-010398-5wot7tix 137 4 that that WDT cord-010398-5wot7tix 137 5 CFS CFS NNP cord-010398-5wot7tix 137 6 typically typically RB cord-010398-5wot7tix 137 7 occurs occur VBZ cord-010398-5wot7tix 137 8 in in IN cord-010398-5wot7tix 137 9 patients patient NNS cord-010398-5wot7tix 137 10 who who WP cord-010398-5wot7tix 137 11 had have VBD cord-010398-5wot7tix 137 12 high high JJ cord-010398-5wot7tix 137 13 premorbid premorbid NN cord-010398-5wot7tix 137 14 levels level NNS cord-010398-5wot7tix 137 15 of of IN cord-010398-5wot7tix 137 16 activity activity NN cord-010398-5wot7tix 137 17 , , , cord-010398-5wot7tix 137 18 and and CC cord-010398-5wot7tix 137 19 , , , cord-010398-5wot7tix 137 20 in in IN cord-010398-5wot7tix 137 21 fact fact NN cord-010398-5wot7tix 137 22 , , , cord-010398-5wot7tix 137 23 high high JJ cord-010398-5wot7tix 137 24 premorbid premorbid NN cord-010398-5wot7tix 137 25 levels level NNS cord-010398-5wot7tix 137 26 of of IN cord-010398-5wot7tix 137 27 activity activity NN cord-010398-5wot7tix 137 28 and and CC cord-010398-5wot7tix 137 29 a a DT cord-010398-5wot7tix 137 30 lower low JJR cord-010398-5wot7tix 137 31 body body NN cord-010398-5wot7tix 137 32 mass mass NN cord-010398-5wot7tix 137 33 in in IN cord-010398-5wot7tix 137 34 young young JJ cord-010398-5wot7tix 137 35 adulthood adulthood NN cord-010398-5wot7tix 137 36 were be VBD cord-010398-5wot7tix 137 37 the the DT cord-010398-5wot7tix 137 38 strongest strong JJS cord-010398-5wot7tix 137 39 predictors predictor NNS cord-010398-5wot7tix 137 40 of of IN cord-010398-5wot7tix 137 41 CFS CFS NNP cord-010398-5wot7tix 137 42 later later RB cord-010398-5wot7tix 137 43 in in IN cord-010398-5wot7tix 137 44 life life NN cord-010398-5wot7tix 137 45 [ [ -LRB- cord-010398-5wot7tix 137 46 27 27 CD cord-010398-5wot7tix 137 47 , , , cord-010398-5wot7tix 137 48 65 65 CD cord-010398-5wot7tix 137 49 ] ] -RRB- cord-010398-5wot7tix 137 50 . . . cord-010398-5wot7tix 138 1 Patients patient NNS cord-010398-5wot7tix 138 2 often often RB cord-010398-5wot7tix 138 3 report report VBP cord-010398-5wot7tix 138 4 excellent excellent JJ cord-010398-5wot7tix 138 5 preillness preillness NN cord-010398-5wot7tix 138 6 physical physical JJ cord-010398-5wot7tix 138 7 fitness fitness NN cord-010398-5wot7tix 138 8 and and CC cord-010398-5wot7tix 138 9 energy energy NN cord-010398-5wot7tix 138 10 and and CC cord-010398-5wot7tix 138 11 an an DT cord-010398-5wot7tix 138 12 abrupt abrupt JJ cord-010398-5wot7tix 138 13 onset onset NN cord-010398-5wot7tix 138 14 of of IN cord-010398-5wot7tix 138 15 fatigue fatigue NN cord-010398-5wot7tix 138 16 . . . cord-010398-5wot7tix 139 1 After after IN cord-010398-5wot7tix 139 2 the the DT cord-010398-5wot7tix 139 3 onset onset NN cord-010398-5wot7tix 139 4 of of IN cord-010398-5wot7tix 139 5 illness illness NN cord-010398-5wot7tix 139 6 , , , cord-010398-5wot7tix 139 7 patients patient NNS cord-010398-5wot7tix 139 8 indicate indicate VBP cord-010398-5wot7tix 139 9 that that IN cord-010398-5wot7tix 139 10 physical physical JJ cord-010398-5wot7tix 139 11 exertion exertion NN cord-010398-5wot7tix 139 12 tends tend VBZ cord-010398-5wot7tix 139 13 to to TO cord-010398-5wot7tix 139 14 exacerbate exacerbate VB cord-010398-5wot7tix 139 15 the the DT cord-010398-5wot7tix 139 16 fatigue fatigue NN cord-010398-5wot7tix 139 17 . . . cord-010398-5wot7tix 140 1 Glass Glass NNP cord-010398-5wot7tix 140 2 et et FW cord-010398-5wot7tix 140 3 al al NNP cord-010398-5wot7tix 140 4 [ [ -LRB- cord-010398-5wot7tix 140 5 66 66 CD cord-010398-5wot7tix 140 6 ] ] -RRB- cord-010398-5wot7tix 140 7 demonstrated demonstrate VBD cord-010398-5wot7tix 140 8 that that IN cord-010398-5wot7tix 140 9 within within IN cord-010398-5wot7tix 140 10 a a DT cord-010398-5wot7tix 140 11 group group NN cord-010398-5wot7tix 140 12 of of IN cord-010398-5wot7tix 140 13 healthy healthy JJ cord-010398-5wot7tix 140 14 , , , cord-010398-5wot7tix 140 15 young young JJ cord-010398-5wot7tix 140 16 subjects subject NNS cord-010398-5wot7tix 140 17 , , , cord-010398-5wot7tix 140 18 the the DT cord-010398-5wot7tix 140 19 ones one NNS cord-010398-5wot7tix 140 20 who who WP cord-010398-5wot7tix 140 21 developed develop VBD cord-010398-5wot7tix 140 22 multiple multiple JJ cord-010398-5wot7tix 140 23 somatic somatic JJ cord-010398-5wot7tix 140 24 symptoms symptom NNS cord-010398-5wot7tix 140 25 after after IN cord-010398-5wot7tix 140 26 experimental experimental JJ cord-010398-5wot7tix 140 27 exercise exercise NN cord-010398-5wot7tix 140 28 cessation cessation NN cord-010398-5wot7tix 140 29 were be VBD cord-010398-5wot7tix 140 30 those those DT cord-010398-5wot7tix 140 31 that that WDT cord-010398-5wot7tix 140 32 had have VBD cord-010398-5wot7tix 140 33 autonomic autonomic JJ cord-010398-5wot7tix 140 34 and and CC cord-010398-5wot7tix 140 35 immune immune JJ cord-010398-5wot7tix 140 36 profiles profile NNS cord-010398-5wot7tix 140 37 resembling resemble VBG cord-010398-5wot7tix 140 38 those those DT cord-010398-5wot7tix 140 39 of of IN cord-010398-5wot7tix 140 40 CFS CFS NNP cord-010398-5wot7tix 140 41 patients patient NNS cord-010398-5wot7tix 140 42 . . . cord-010398-5wot7tix 141 1 Recent recent JJ cord-010398-5wot7tix 141 2 studies study NNS cord-010398-5wot7tix 141 3 performed perform VBN cord-010398-5wot7tix 141 4 by by IN cord-010398-5wot7tix 141 5 our -PRON- PRP$ cord-010398-5wot7tix 141 6 group group NN cord-010398-5wot7tix 141 7 further further RB cord-010398-5wot7tix 141 8 examined examine VBD cord-010398-5wot7tix 141 9 the the DT cord-010398-5wot7tix 141 10 additive additive NN cord-010398-5wot7tix 141 11 and and CC cord-010398-5wot7tix 141 12 synergistic synergistic JJ cord-010398-5wot7tix 141 13 roles role NNS cord-010398-5wot7tix 141 14 that that WDT cord-010398-5wot7tix 141 15 sleep sleep VBP cord-010398-5wot7tix 141 16 restriction restriction NN cord-010398-5wot7tix 141 17 and and CC cord-010398-5wot7tix 141 18 exercise exercise NN cord-010398-5wot7tix 141 19 cessation cessation NN cord-010398-5wot7tix 141 20 have have VBP cord-010398-5wot7tix 141 21 on on IN cord-010398-5wot7tix 141 22 the the DT cord-010398-5wot7tix 141 23 development development NN cord-010398-5wot7tix 141 24 of of IN cord-010398-5wot7tix 141 25 somatic somatic JJ cord-010398-5wot7tix 141 26 symptoms symptom NNS cord-010398-5wot7tix 141 27 in in IN cord-010398-5wot7tix 141 28 healthy healthy JJ cord-010398-5wot7tix 141 29 patients patient NNS cord-010398-5wot7tix 141 30 and and CC cord-010398-5wot7tix 141 31 demonstrated demonstrate VBD cord-010398-5wot7tix 141 32 that that IN cord-010398-5wot7tix 141 33 regular regular JJ cord-010398-5wot7tix 141 34 exercise exercise NN cord-010398-5wot7tix 141 35 seems seem VBZ cord-010398-5wot7tix 141 36 to to TO cord-010398-5wot7tix 141 37 buffer buffer VB cord-010398-5wot7tix 141 38 some some DT cord-010398-5wot7tix 141 39 of of IN cord-010398-5wot7tix 141 40 the the DT cord-010398-5wot7tix 141 41 adverse adverse JJ cord-010398-5wot7tix 141 42 effects effect NNS cord-010398-5wot7tix 141 43 of of IN cord-010398-5wot7tix 141 44 sleep sleep NN cord-010398-5wot7tix 141 45 on on IN cord-010398-5wot7tix 141 46 symptom symptom NN cord-010398-5wot7tix 141 47 development development NN cord-010398-5wot7tix 141 48 . . . cord-010398-5wot7tix 142 1 Female female JJ cord-010398-5wot7tix 142 2 patients patient NNS cord-010398-5wot7tix 142 3 were be VBD cord-010398-5wot7tix 142 4 much much RB cord-010398-5wot7tix 142 5 more more RBR cord-010398-5wot7tix 142 6 likely likely JJ cord-010398-5wot7tix 142 7 to to TO cord-010398-5wot7tix 142 8 have have VB cord-010398-5wot7tix 142 9 somatic somatic JJ cord-010398-5wot7tix 142 10 symptoms symptom NNS cord-010398-5wot7tix 142 11 when when WRB cord-010398-5wot7tix 142 12 deprived deprive VBN cord-010398-5wot7tix 142 13 of of IN cord-010398-5wot7tix 142 14 either either DT cord-010398-5wot7tix 142 15 sleep sleep NN cord-010398-5wot7tix 142 16 or or CC cord-010398-5wot7tix 142 17 exercise exercise NN cord-010398-5wot7tix 142 18 . . . cord-010398-5wot7tix 143 1 Because because IN cord-010398-5wot7tix 143 2 of of IN cord-010398-5wot7tix 143 3 their -PRON- PRP$ cord-010398-5wot7tix 143 4 frequent frequent JJ cord-010398-5wot7tix 143 5 co co NN cord-010398-5wot7tix 143 6 - - NN cord-010398-5wot7tix 143 7 occurrence occurrence JJ cord-010398-5wot7tix 143 8 , , , cord-010398-5wot7tix 143 9 psychiatric psychiatric JJ cord-010398-5wot7tix 143 10 and and CC cord-010398-5wot7tix 143 11 psychological psychological JJ cord-010398-5wot7tix 143 12 abnormalities abnormality NNS cord-010398-5wot7tix 143 13 have have VBP cord-010398-5wot7tix 143 14 also also RB cord-010398-5wot7tix 143 15 been be VBN cord-010398-5wot7tix 143 16 very very RB cord-010398-5wot7tix 143 17 well well RB cord-010398-5wot7tix 143 18 - - HYPH cord-010398-5wot7tix 143 19 studied study VBN cord-010398-5wot7tix 143 20 in in IN cord-010398-5wot7tix 143 21 CFS CFS NNP cord-010398-5wot7tix 143 22 . . . cord-010398-5wot7tix 144 1 With with IN cord-010398-5wot7tix 144 2 the the DT cord-010398-5wot7tix 144 3 advent advent NN cord-010398-5wot7tix 144 4 of of IN cord-010398-5wot7tix 144 5 a a DT cord-010398-5wot7tix 144 6 better well JJR cord-010398-5wot7tix 144 7 understanding understanding NN cord-010398-5wot7tix 144 8 of of IN cord-010398-5wot7tix 144 9 the the DT cord-010398-5wot7tix 144 10 neurobiology neurobiology NN cord-010398-5wot7tix 144 11 of of IN cord-010398-5wot7tix 144 12 these these DT cord-010398-5wot7tix 144 13 illnesses illness NNS cord-010398-5wot7tix 144 14 , , , cord-010398-5wot7tix 144 15 investigators investigator NNS cord-010398-5wot7tix 144 16 who who WP cord-010398-5wot7tix 144 17 once once RB cord-010398-5wot7tix 144 18 staunchly staunchly RB cord-010398-5wot7tix 144 19 viewed view VBD cord-010398-5wot7tix 144 20 CFS CFS NNP cord-010398-5wot7tix 144 21 as as IN cord-010398-5wot7tix 144 22 a a DT cord-010398-5wot7tix 144 23 psychiatric psychiatric JJ cord-010398-5wot7tix 144 24 condition condition NN cord-010398-5wot7tix 144 25 have have VBP cord-010398-5wot7tix 144 26 significantly significantly RB cord-010398-5wot7tix 144 27 tempered temper VBN cord-010398-5wot7tix 144 28 their -PRON- PRP$ cord-010398-5wot7tix 144 29 views view NNS cord-010398-5wot7tix 144 30 , , , cord-010398-5wot7tix 144 31 now now RB cord-010398-5wot7tix 144 32 acknowledging acknowledge VBG cord-010398-5wot7tix 144 33 that that IN cord-010398-5wot7tix 144 34 these these DT cord-010398-5wot7tix 144 35 conditions condition NNS cord-010398-5wot7tix 144 36 are be VBP cord-010398-5wot7tix 144 37 clearly clearly RB cord-010398-5wot7tix 144 38 separable separable JJ cord-010398-5wot7tix 144 39 from from IN cord-010398-5wot7tix 144 40 , , , cord-010398-5wot7tix 144 41 and and CC cord-010398-5wot7tix 144 42 often often RB cord-010398-5wot7tix 144 43 occur occur VBP cord-010398-5wot7tix 144 44 independently independently RB cord-010398-5wot7tix 144 45 of of IN cord-010398-5wot7tix 144 46 , , , cord-010398-5wot7tix 144 47 psychiatric psychiatric JJ cord-010398-5wot7tix 144 48 disorders disorder NNS cord-010398-5wot7tix 144 49 [ [ -LRB- cord-010398-5wot7tix 144 50 67 67 CD cord-010398-5wot7tix 144 51 , , , cord-010398-5wot7tix 144 52 68 68 CD cord-010398-5wot7tix 144 53 ] ] -RRB- cord-010398-5wot7tix 144 54 . . . cord-010398-5wot7tix 145 1 As as IN cord-010398-5wot7tix 145 2 noted note VBN cord-010398-5wot7tix 145 3 previously previously RB cord-010398-5wot7tix 145 4 , , , cord-010398-5wot7tix 145 5 both both CC cord-010398-5wot7tix 145 6 epidemiologic epidemiologic JJ cord-010398-5wot7tix 145 7 and and CC cord-010398-5wot7tix 145 8 twin twin JJ cord-010398-5wot7tix 145 9 studies study NNS cord-010398-5wot7tix 145 10 have have VBP cord-010398-5wot7tix 145 11 shown show VBN cord-010398-5wot7tix 145 12 that that IN cord-010398-5wot7tix 145 13 CFS cfs NN cord-010398-5wot7tix 145 14 and and CC cord-010398-5wot7tix 145 15 other other JJ cord-010398-5wot7tix 145 16 CSS css NN cord-010398-5wot7tix 145 17 are be VBP cord-010398-5wot7tix 145 18 clearly clearly RB cord-010398-5wot7tix 145 19 separate separate JJ cord-010398-5wot7tix 145 20 from from IN cord-010398-5wot7tix 145 21 conditions condition NNS cord-010398-5wot7tix 145 22 such such JJ cord-010398-5wot7tix 145 23 as as IN cord-010398-5wot7tix 145 24 anxiety anxiety NN cord-010398-5wot7tix 145 25 and and CC cord-010398-5wot7tix 145 26 depression depression NN cord-010398-5wot7tix 145 27 [ [ -LRB- cord-010398-5wot7tix 145 28 39 39 CD cord-010398-5wot7tix 145 29 ] ] -RRB- cord-010398-5wot7tix 145 30 . . . cord-010398-5wot7tix 146 1 Patients patient NNS cord-010398-5wot7tix 146 2 with with IN cord-010398-5wot7tix 146 3 psychiatric psychiatric JJ cord-010398-5wot7tix 146 4 conditions condition NNS cord-010398-5wot7tix 146 5 earlier early RBR cord-010398-5wot7tix 146 6 in in IN cord-010398-5wot7tix 146 7 life life NN cord-010398-5wot7tix 146 8 have have VBP cord-010398-5wot7tix 146 9 a a DT cord-010398-5wot7tix 146 10 2 2 CD cord-010398-5wot7tix 146 11 to to TO cord-010398-5wot7tix 146 12 3 3 CD cord-010398-5wot7tix 146 13 times time NNS cord-010398-5wot7tix 146 14 greater great JJR cord-010398-5wot7tix 146 15 risk risk NN cord-010398-5wot7tix 146 16 of of IN cord-010398-5wot7tix 146 17 developing develop VBG cord-010398-5wot7tix 146 18 CFS CFS NNP cord-010398-5wot7tix 146 19 than than IN cord-010398-5wot7tix 146 20 those those DT cord-010398-5wot7tix 146 21 who who WP cord-010398-5wot7tix 146 22 do do VBP cord-010398-5wot7tix 146 23 not not RB cord-010398-5wot7tix 146 24 have have VB cord-010398-5wot7tix 146 25 premorbid premorbid VBN cord-010398-5wot7tix 146 26 psychiatric psychiatric JJ cord-010398-5wot7tix 146 27 diagnoses diagnosis NNS cord-010398-5wot7tix 146 28 , , , cord-010398-5wot7tix 146 29 but but CC cord-010398-5wot7tix 146 30 this this DT cord-010398-5wot7tix 146 31 still still RB cord-010398-5wot7tix 146 32 means mean VBZ cord-010398-5wot7tix 146 33 that that IN cord-010398-5wot7tix 146 34 most most JJS cord-010398-5wot7tix 146 35 patients patient NNS cord-010398-5wot7tix 146 36 with with IN cord-010398-5wot7tix 146 37 CFS CFS NNP cord-010398-5wot7tix 146 38 in in IN cord-010398-5wot7tix 146 39 the the DT cord-010398-5wot7tix 146 40 general general JJ cord-010398-5wot7tix 146 41 population population NN cord-010398-5wot7tix 146 42 neither neither CC cord-010398-5wot7tix 146 43 had have VBD cord-010398-5wot7tix 146 44 or or CC cord-010398-5wot7tix 146 45 have have VB cord-010398-5wot7tix 146 46 a a DT cord-010398-5wot7tix 146 47 diagnosable diagnosable JJ cord-010398-5wot7tix 146 48 psychiatric psychiatric JJ cord-010398-5wot7tix 146 49 condition condition NN cord-010398-5wot7tix 146 50 [ [ -LRB- cord-010398-5wot7tix 146 51 69 69 CD cord-010398-5wot7tix 146 52 ] ] -RRB- cord-010398-5wot7tix 146 53 . . . cord-010398-5wot7tix 147 1 Studies study NNS cord-010398-5wot7tix 147 2 have have VBP cord-010398-5wot7tix 147 3 not not RB cord-010398-5wot7tix 147 4 found find VBN cord-010398-5wot7tix 147 5 personality personality NN cord-010398-5wot7tix 147 6 disorders disorder NNS cord-010398-5wot7tix 147 7 to to TO cord-010398-5wot7tix 147 8 be be VB cord-010398-5wot7tix 147 9 more more RBR cord-010398-5wot7tix 147 10 prevalent prevalent JJ cord-010398-5wot7tix 147 11 in in IN cord-010398-5wot7tix 147 12 people people NNS cord-010398-5wot7tix 147 13 with with IN cord-010398-5wot7tix 147 14 CFS CFS NNP cord-010398-5wot7tix 147 15 . . . cord-010398-5wot7tix 148 1 This this DT cord-010398-5wot7tix 148 2 finding finding NN cord-010398-5wot7tix 148 3 dispels dispel VBZ cord-010398-5wot7tix 148 4 the the DT cord-010398-5wot7tix 148 5 misconception misconception NN cord-010398-5wot7tix 148 6 that that IN cord-010398-5wot7tix 148 7 these these DT cord-010398-5wot7tix 148 8 are be VBP cord-010398-5wot7tix 148 9 type type NN cord-010398-5wot7tix 148 10 A a DT cord-010398-5wot7tix 148 11 individuals individual NNS cord-010398-5wot7tix 148 12 who who WP cord-010398-5wot7tix 148 13 become become VBP cord-010398-5wot7tix 148 14 dissatisfied dissatisfied JJ cord-010398-5wot7tix 148 15 with with IN cord-010398-5wot7tix 148 16 their -PRON- PRP$ cord-010398-5wot7tix 148 17 inability inability NN cord-010398-5wot7tix 148 18 to to TO cord-010398-5wot7tix 148 19 perform perform VB cord-010398-5wot7tix 148 20 tasks task NNS cord-010398-5wot7tix 148 21 that that IN cord-010398-5wot7tix 148 22 others other NNS cord-010398-5wot7tix 148 23 also also RB cord-010398-5wot7tix 148 24 can can MD cord-010398-5wot7tix 148 25 not not RB cord-010398-5wot7tix 148 26 perform perform VB cord-010398-5wot7tix 148 27 . . . cord-010398-5wot7tix 149 1 More More JJR cord-010398-5wot7tix 149 2 recent recent JJ cord-010398-5wot7tix 149 3 studies study NNS cord-010398-5wot7tix 149 4 , , , cord-010398-5wot7tix 149 5 however however RB cord-010398-5wot7tix 149 6 , , , cord-010398-5wot7tix 149 7 did do VBD cord-010398-5wot7tix 149 8 show show VB cord-010398-5wot7tix 149 9 that that IN cord-010398-5wot7tix 149 10 a a DT cord-010398-5wot7tix 149 11 personality personality NN cord-010398-5wot7tix 149 12 trait trait NN cord-010398-5wot7tix 149 13 , , , cord-010398-5wot7tix 149 14 neuroticism neuroticism NN cord-010398-5wot7tix 149 15 , , , cord-010398-5wot7tix 149 16 was be VBD cord-010398-5wot7tix 149 17 associated associate VBN cord-010398-5wot7tix 149 18 with with IN cord-010398-5wot7tix 149 19 more more JJR cord-010398-5wot7tix 149 20 severe severe JJ cord-010398-5wot7tix 149 21 symptoms symptom NNS cord-010398-5wot7tix 149 22 in in IN cord-010398-5wot7tix 149 23 those those DT cord-010398-5wot7tix 149 24 with with IN cord-010398-5wot7tix 149 25 CFS CFS NNP cord-010398-5wot7tix 149 26 [ [ -LRB- cord-010398-5wot7tix 149 27 69 69 CD cord-010398-5wot7tix 149 28 , , , cord-010398-5wot7tix 149 29 70 70 CD cord-010398-5wot7tix 149 30 ] ] -RRB- cord-010398-5wot7tix 149 31 . . . cord-010398-5wot7tix 150 1 It -PRON- PRP cord-010398-5wot7tix 150 2 is be VBZ cord-010398-5wot7tix 150 3 best good JJS cord-010398-5wot7tix 150 4 to to TO cord-010398-5wot7tix 150 5 think think VB cord-010398-5wot7tix 150 6 of of IN cord-010398-5wot7tix 150 7 psychological psychological JJ cord-010398-5wot7tix 150 8 and and CC cord-010398-5wot7tix 150 9 psychiatric psychiatric JJ cord-010398-5wot7tix 150 10 symptoms symptom NNS cord-010398-5wot7tix 150 11 similarly similarly RB cord-010398-5wot7tix 150 12 to to TO cord-010398-5wot7tix 150 13 sleep sleep VB cord-010398-5wot7tix 150 14 or or CC cord-010398-5wot7tix 150 15 cognitive cognitive JJ cord-010398-5wot7tix 150 16 disturbances disturbance NNS cord-010398-5wot7tix 150 17 in in IN cord-010398-5wot7tix 150 18 CFS CFS NNP cord-010398-5wot7tix 150 19 , , , cord-010398-5wot7tix 150 20 that that RB cord-010398-5wot7tix 150 21 is is RB cord-010398-5wot7tix 150 22 , , , cord-010398-5wot7tix 150 23 as as IN cord-010398-5wot7tix 150 24 a a DT cord-010398-5wot7tix 150 25 domain domain NN cord-010398-5wot7tix 150 26 that that WDT cord-010398-5wot7tix 150 27 is be VBZ cord-010398-5wot7tix 150 28 important important JJ cord-010398-5wot7tix 150 29 to to TO cord-010398-5wot7tix 150 30 evaluate evaluate VB cord-010398-5wot7tix 150 31 in in IN cord-010398-5wot7tix 150 32 patients patient NNS cord-010398-5wot7tix 150 33 with with IN cord-010398-5wot7tix 150 34 CFS CFS NNP cord-010398-5wot7tix 150 35 because because IN cord-010398-5wot7tix 150 36 abnormalities abnormality NNS cord-010398-5wot7tix 150 37 can can MD cord-010398-5wot7tix 150 38 often often RB cord-010398-5wot7tix 150 39 be be VB cord-010398-5wot7tix 150 40 identified identify VBN cord-010398-5wot7tix 150 41 . . . cord-010398-5wot7tix 151 1 When when WRB cord-010398-5wot7tix 151 2 these these DT cord-010398-5wot7tix 151 3 comorbidities comorbiditie NNS cord-010398-5wot7tix 151 4 occur occur VBP cord-010398-5wot7tix 151 5 , , , cord-010398-5wot7tix 151 6 they -PRON- PRP cord-010398-5wot7tix 151 7 often often RB cord-010398-5wot7tix 151 8 add add VBP cord-010398-5wot7tix 151 9 to to IN cord-010398-5wot7tix 151 10 the the DT cord-010398-5wot7tix 151 11 functional functional JJ cord-010398-5wot7tix 151 12 burden burden NN cord-010398-5wot7tix 151 13 of of IN cord-010398-5wot7tix 151 14 the the DT cord-010398-5wot7tix 151 15 illness illness NN cord-010398-5wot7tix 151 16 , , , cord-010398-5wot7tix 151 17 because because IN cord-010398-5wot7tix 151 18 depression depression NN cord-010398-5wot7tix 151 19 in in IN cord-010398-5wot7tix 151 20 addition addition NN cord-010398-5wot7tix 151 21 to to IN cord-010398-5wot7tix 151 22 CFS CFS NNP cord-010398-5wot7tix 151 23 is be VBZ cord-010398-5wot7tix 151 24 likely likely JJ cord-010398-5wot7tix 151 25 to to TO cord-010398-5wot7tix 151 26 be be VB cord-010398-5wot7tix 151 27 associated associate VBN cord-010398-5wot7tix 151 28 with with IN cord-010398-5wot7tix 151 29 disability disability NN cord-010398-5wot7tix 151 30 and and CC cord-010398-5wot7tix 151 31 fatigue fatigue NN cord-010398-5wot7tix 151 32 [ [ -LRB- cord-010398-5wot7tix 151 33 71 71 CD cord-010398-5wot7tix 151 34 ] ] -RRB- cord-010398-5wot7tix 151 35 . . . cord-010398-5wot7tix 152 1 Although although IN cord-010398-5wot7tix 152 2 the the DT cord-010398-5wot7tix 152 3 CSS css NN cord-010398-5wot7tix 152 4 conditions condition NNS cord-010398-5wot7tix 152 5 all all DT cord-010398-5wot7tix 152 6 were be VBD cord-010398-5wot7tix 152 7 originally originally RB cord-010398-5wot7tix 152 8 thought think VBN cord-010398-5wot7tix 152 9 to to TO cord-010398-5wot7tix 152 10 be be VB cord-010398-5wot7tix 152 11 autoimmune autoimmune JJ cord-010398-5wot7tix 152 12 or or CC cord-010398-5wot7tix 152 13 inflammatory inflammatory JJ cord-010398-5wot7tix 152 14 diseases disease NNS cord-010398-5wot7tix 152 15 , , , cord-010398-5wot7tix 152 16 CFS CFS NNP cord-010398-5wot7tix 152 17 is be VBZ cord-010398-5wot7tix 152 18 one one CD cord-010398-5wot7tix 152 19 condition condition NN cord-010398-5wot7tix 152 20 in in IN cord-010398-5wot7tix 152 21 which which WDT cord-010398-5wot7tix 152 22 there there EX cord-010398-5wot7tix 152 23 are be VBP cord-010398-5wot7tix 152 24 still still RB cord-010398-5wot7tix 152 25 a a DT cord-010398-5wot7tix 152 26 sizable sizable JJ cord-010398-5wot7tix 152 27 number number NN cord-010398-5wot7tix 152 28 of of IN cord-010398-5wot7tix 152 29 clinicians clinician NNS cord-010398-5wot7tix 152 30 and and CC cord-010398-5wot7tix 152 31 investigators investigator NNS cord-010398-5wot7tix 152 32 who who WP cord-010398-5wot7tix 152 33 believe believe VBP cord-010398-5wot7tix 152 34 that that IN cord-010398-5wot7tix 152 35 ongoing ongoing JJ cord-010398-5wot7tix 152 36 infection infection NN cord-010398-5wot7tix 152 37 and/or and/or CC cord-010398-5wot7tix 152 38 inflammation inflammation NN cord-010398-5wot7tix 152 39 plays play VBZ cord-010398-5wot7tix 152 40 a a DT cord-010398-5wot7tix 152 41 significant significant JJ cord-010398-5wot7tix 152 42 role role NN cord-010398-5wot7tix 152 43 in in IN cord-010398-5wot7tix 152 44 some some DT cord-010398-5wot7tix 152 45 patients patient NNS cord-010398-5wot7tix 152 46 . . . cord-010398-5wot7tix 153 1 One one CD cord-010398-5wot7tix 153 2 of of IN cord-010398-5wot7tix 153 3 the the DT cord-010398-5wot7tix 153 4 reasons reason NNS cord-010398-5wot7tix 153 5 that that WDT cord-010398-5wot7tix 153 6 CFS CFS NNP cord-010398-5wot7tix 153 7 had have VBD cord-010398-5wot7tix 153 8 long long RB cord-010398-5wot7tix 153 9 been be VBN cord-010398-5wot7tix 153 10 considered consider VBN cord-010398-5wot7tix 153 11 an an DT cord-010398-5wot7tix 153 12 infectious infectious JJ cord-010398-5wot7tix 153 13 disease disease NN cord-010398-5wot7tix 153 14 is be VBZ cord-010398-5wot7tix 153 15 that that IN cord-010398-5wot7tix 153 16 it -PRON- PRP cord-010398-5wot7tix 153 17 is be VBZ cord-010398-5wot7tix 153 18 very very RB cord-010398-5wot7tix 153 19 clear clear JJ cord-010398-5wot7tix 153 20 that that IN cord-010398-5wot7tix 153 21 this this DT cord-010398-5wot7tix 153 22 symptom symptom NN cord-010398-5wot7tix 153 23 complex complex NN cord-010398-5wot7tix 153 24 can can MD cord-010398-5wot7tix 153 25 be be VB cord-010398-5wot7tix 153 26 triggered trigger VBN cord-010398-5wot7tix 153 27 by by IN cord-010398-5wot7tix 153 28 a a DT cord-010398-5wot7tix 153 29 variety variety NN cord-010398-5wot7tix 153 30 of of IN cord-010398-5wot7tix 153 31 infections infection NNS cord-010398-5wot7tix 153 32 , , , cord-010398-5wot7tix 153 33 including include VBG cord-010398-5wot7tix 153 34 the the DT cord-010398-5wot7tix 153 35 EBV EBV NNP cord-010398-5wot7tix 153 36 , , , cord-010398-5wot7tix 153 37 Q Q NNP cord-010398-5wot7tix 153 38 fever fever NN cord-010398-5wot7tix 153 39 , , , cord-010398-5wot7tix 153 40 and and CC cord-010398-5wot7tix 153 41 Lyme Lyme NNP cord-010398-5wot7tix 153 42 disease disease NN cord-010398-5wot7tix 153 43 , , , cord-010398-5wot7tix 153 44 among among IN cord-010398-5wot7tix 153 45 others other NNS cord-010398-5wot7tix 153 46 [ [ -LRB- cord-010398-5wot7tix 153 47 72 72 CD cord-010398-5wot7tix 153 48 ] ] -RRB- cord-010398-5wot7tix 153 49 . . . cord-010398-5wot7tix 154 1 Just just RB cord-010398-5wot7tix 154 2 recently recently RB cord-010398-5wot7tix 154 3 , , , cord-010398-5wot7tix 154 4 infections infection NNS cord-010398-5wot7tix 154 5 with with IN cord-010398-5wot7tix 154 6 unusual unusual JJ cord-010398-5wot7tix 154 7 or or CC cord-010398-5wot7tix 154 8 newly newly RB cord-010398-5wot7tix 154 9 discovered discover VBN cord-010398-5wot7tix 154 10 pathogens pathogen NNS cord-010398-5wot7tix 154 11 such such JJ cord-010398-5wot7tix 154 12 as as IN cord-010398-5wot7tix 154 13 the the DT cord-010398-5wot7tix 154 14 West West NNP cord-010398-5wot7tix 154 15 Nile Nile NNP cord-010398-5wot7tix 154 16 virus virus NN cord-010398-5wot7tix 154 17 , , , cord-010398-5wot7tix 154 18 severe severe JJ cord-010398-5wot7tix 154 19 acute acute JJ cord-010398-5wot7tix 154 20 respiratory respiratory JJ cord-010398-5wot7tix 154 21 syndrome syndrome NN cord-010398-5wot7tix 154 22 ( ( -LRB- cord-010398-5wot7tix 154 23 ie ie FW cord-010398-5wot7tix 154 24 , , , cord-010398-5wot7tix 154 25 SARS SARS NNP cord-010398-5wot7tix 154 26 ) ) -RRB- cord-010398-5wot7tix 154 27 , , , cord-010398-5wot7tix 154 28 and and CC cord-010398-5wot7tix 154 29 the the DT cord-010398-5wot7tix 154 30 H1N1 H1N1 NNP cord-010398-5wot7tix 154 31 flu flu NN cord-010398-5wot7tix 154 32 have have VBP cord-010398-5wot7tix 154 33 all all DT cord-010398-5wot7tix 154 34 been be VBN cord-010398-5wot7tix 154 35 shown show VBN cord-010398-5wot7tix 154 36 to to TO cord-010398-5wot7tix 154 37 lead lead VB cord-010398-5wot7tix 154 38 to to IN cord-010398-5wot7tix 154 39 the the DT cord-010398-5wot7tix 154 40 development development NN cord-010398-5wot7tix 154 41 of of IN cord-010398-5wot7tix 154 42 CFS CFS NNP cord-010398-5wot7tix 154 43 [ [ -LRB- cord-010398-5wot7tix 154 44 73 73 CD cord-010398-5wot7tix 154 45 ] ] -RRB- cord-010398-5wot7tix 154 46 [ [ -LRB- cord-010398-5wot7tix 154 47 74 74 CD cord-010398-5wot7tix 154 48 ] ] -RRB- cord-010398-5wot7tix 154 49 [ [ -LRB- cord-010398-5wot7tix 154 50 75 75 CD cord-010398-5wot7tix 154 51 ] ] -RRB- cord-010398-5wot7tix 154 52 . . . cord-010398-5wot7tix 155 1 A a DT cord-010398-5wot7tix 155 2 broader broad JJR cord-010398-5wot7tix 155 3 examination examination NN cord-010398-5wot7tix 155 4 of of IN cord-010398-5wot7tix 155 5 the the DT cord-010398-5wot7tix 155 6 role role NN cord-010398-5wot7tix 155 7 of of IN cord-010398-5wot7tix 155 8 a a DT cord-010398-5wot7tix 155 9 variety variety NN cord-010398-5wot7tix 155 10 of of IN cord-010398-5wot7tix 155 11 stressors stressor NNS cord-010398-5wot7tix 155 12 in in IN cord-010398-5wot7tix 155 13 triggering trigger VBG cord-010398-5wot7tix 155 14 this this DT cord-010398-5wot7tix 155 15 symptom symptom NN cord-010398-5wot7tix 155 16 complex complex NN cord-010398-5wot7tix 155 17 helps help VBZ cord-010398-5wot7tix 155 18 put put VB cord-010398-5wot7tix 155 19 this this DT cord-010398-5wot7tix 155 20 phenomenon phenomenon NN cord-010398-5wot7tix 155 21 in in IN cord-010398-5wot7tix 155 22 perspective perspective NN cord-010398-5wot7tix 155 23 . . . cord-010398-5wot7tix 156 1 Arguably arguably RB cord-010398-5wot7tix 156 2 the the DT cord-010398-5wot7tix 156 3 best good JJS cord-010398-5wot7tix 156 4 set set NN cord-010398-5wot7tix 156 5 of of IN cord-010398-5wot7tix 156 6 studies study NNS cord-010398-5wot7tix 156 7 examining examine VBG cord-010398-5wot7tix 156 8 the the DT cord-010398-5wot7tix 156 9 underlying underlie VBG cord-010398-5wot7tix 156 10 mechanisms mechanism NNS cord-010398-5wot7tix 156 11 that that WDT cord-010398-5wot7tix 156 12 are be VBP cord-010398-5wot7tix 156 13 operative operative JJ cord-010398-5wot7tix 156 14 in in IN cord-010398-5wot7tix 156 15 postinfectious postinfectious NNP cord-010398-5wot7tix 156 16 CFS CFS NNP cord-010398-5wot7tix 156 17 are be VBP cord-010398-5wot7tix 156 18 from from IN cord-010398-5wot7tix 156 19 a a DT cord-010398-5wot7tix 156 20 large large JJ cord-010398-5wot7tix 156 21 longitudinal longitudinal JJ cord-010398-5wot7tix 156 22 study study NN cord-010398-5wot7tix 156 23 in in IN cord-010398-5wot7tix 156 24 which which WDT cord-010398-5wot7tix 156 25 the the DT cord-010398-5wot7tix 156 26 authors author NNS cord-010398-5wot7tix 156 27 analyzed analyze VBD cord-010398-5wot7tix 156 28 the the DT cord-010398-5wot7tix 156 29 long long JJ cord-010398-5wot7tix 156 30 - - HYPH cord-010398-5wot7tix 156 31 term term NN cord-010398-5wot7tix 156 32 consequences consequence NNS cord-010398-5wot7tix 156 33 of of IN cord-010398-5wot7tix 156 34 infection infection NN cord-010398-5wot7tix 156 35 with with IN cord-010398-5wot7tix 156 36 3 3 CD cord-010398-5wot7tix 156 37 different different JJ cord-010398-5wot7tix 156 38 pathogens pathogen NNS cord-010398-5wot7tix 156 39 : : : cord-010398-5wot7tix 156 40 the the DT cord-010398-5wot7tix 156 41 Ross Ross NNP cord-010398-5wot7tix 156 42 River River NNP cord-010398-5wot7tix 156 43 virus virus NN cord-010398-5wot7tix 156 44 ( ( -LRB- cord-010398-5wot7tix 156 45 the the DT cord-010398-5wot7tix 156 46 cause cause NN cord-010398-5wot7tix 156 47 of of IN cord-010398-5wot7tix 156 48 epidemic epidemic NN cord-010398-5wot7tix 156 49 polyarthritis polyarthritis NNP cord-010398-5wot7tix 156 50 ) ) -RRB- cord-010398-5wot7tix 156 51 , , , cord-010398-5wot7tix 156 52 Coxiella Coxiella NNP cord-010398-5wot7tix 156 53 burnetii burnetii NNP cord-010398-5wot7tix 156 54 ( ( -LRB- cord-010398-5wot7tix 156 55 the the DT cord-010398-5wot7tix 156 56 cause cause NN cord-010398-5wot7tix 156 57 of of IN cord-010398-5wot7tix 156 58 Q Q NNP cord-010398-5wot7tix 156 59 fever fever NN cord-010398-5wot7tix 156 60 ) ) -RRB- cord-010398-5wot7tix 156 61 , , , cord-010398-5wot7tix 156 62 and and CC cord-010398-5wot7tix 156 63 EBV EBV NNP cord-010398-5wot7tix 156 64 and and CC cord-010398-5wot7tix 156 65 the the DT cord-010398-5wot7tix 156 66 development development NN cord-010398-5wot7tix 156 67 of of IN cord-010398-5wot7tix 156 68 CFS CFS NNP cord-010398-5wot7tix 156 69 [ [ -LRB- cord-010398-5wot7tix 156 70 76 76 CD cord-010398-5wot7tix 156 71 ] ] -RRB- cord-010398-5wot7tix 156 72 . . . cord-010398-5wot7tix 157 1 In in IN cord-010398-5wot7tix 157 2 this this DT cord-010398-5wot7tix 157 3 prospective prospective JJ cord-010398-5wot7tix 157 4 epidemiological epidemiological JJ cord-010398-5wot7tix 157 5 study study NN cord-010398-5wot7tix 157 6 , , , cord-010398-5wot7tix 157 7 patients patient NNS cord-010398-5wot7tix 157 8 experiencing experience VBG cord-010398-5wot7tix 157 9 acute acute JJ cord-010398-5wot7tix 157 10 infection infection NN cord-010398-5wot7tix 157 11 with with IN cord-010398-5wot7tix 157 12 these these DT cord-010398-5wot7tix 157 13 disparate disparate JJ cord-010398-5wot7tix 157 14 pathogens pathogen NNS cord-010398-5wot7tix 157 15 were be VBD cord-010398-5wot7tix 157 16 recruited recruit VBN cord-010398-5wot7tix 157 17 , , , cord-010398-5wot7tix 157 18 followed follow VBN cord-010398-5wot7tix 157 19 for for IN cord-010398-5wot7tix 157 20 12 12 CD cord-010398-5wot7tix 157 21 months month NNS cord-010398-5wot7tix 157 22 , , , cord-010398-5wot7tix 157 23 and and CC cord-010398-5wot7tix 157 24 monitored monitor VBD cord-010398-5wot7tix 157 25 for for IN cord-010398-5wot7tix 157 26 the the DT cord-010398-5wot7tix 157 27 development development NN cord-010398-5wot7tix 157 28 of of IN cord-010398-5wot7tix 157 29 fatigue fatigue NN cord-010398-5wot7tix 157 30 , , , cord-010398-5wot7tix 157 31 muscular muscular JJ cord-010398-5wot7tix 157 32 pain pain NN cord-010398-5wot7tix 157 33 , , , cord-010398-5wot7tix 157 34 cognitive cognitive JJ cord-010398-5wot7tix 157 35 dysfunction dysfunction NN cord-010398-5wot7tix 157 36 , , , cord-010398-5wot7tix 157 37 and and CC cord-010398-5wot7tix 157 38 mood mood NN cord-010398-5wot7tix 157 39 disturbances disturbance NNS cord-010398-5wot7tix 157 40 . . . cord-010398-5wot7tix 158 1 The the DT cord-010398-5wot7tix 158 2 symptom symptom NN cord-010398-5wot7tix 158 3 complex complex NN cord-010398-5wot7tix 158 4 developed develop VBN cord-010398-5wot7tix 158 5 in in IN cord-010398-5wot7tix 158 6 12 12 CD cord-010398-5wot7tix 158 7 % % NN cord-010398-5wot7tix 158 8 of of IN cord-010398-5wot7tix 158 9 the the DT cord-010398-5wot7tix 158 10 patients patient NNS cord-010398-5wot7tix 158 11 at at IN cord-010398-5wot7tix 158 12 12 12 CD cord-010398-5wot7tix 158 13 months month NNS cord-010398-5wot7tix 158 14 . . . cord-010398-5wot7tix 159 1 Although although IN cord-010398-5wot7tix 159 2 these these DT cord-010398-5wot7tix 159 3 infections infection NNS cord-010398-5wot7tix 159 4 cause cause VBP cord-010398-5wot7tix 159 5 markedly markedly RB cord-010398-5wot7tix 159 6 different different JJ cord-010398-5wot7tix 159 7 acute acute JJ cord-010398-5wot7tix 159 8 presentations presentation NNS cord-010398-5wot7tix 159 9 , , , cord-010398-5wot7tix 159 10 a a DT cord-010398-5wot7tix 159 11 very very RB cord-010398-5wot7tix 159 12 stereotypical stereotypical JJ cord-010398-5wot7tix 159 13 chronic chronic JJ cord-010398-5wot7tix 159 14 syndrome syndrome NN cord-010398-5wot7tix 159 15 ( ( -LRB- cord-010398-5wot7tix 159 16 characterized characterize VBN cord-010398-5wot7tix 159 17 by by IN cord-010398-5wot7tix 159 18 pain pain NN cord-010398-5wot7tix 159 19 , , , cord-010398-5wot7tix 159 20 fatigue fatigue NN cord-010398-5wot7tix 159 21 , , , cord-010398-5wot7tix 159 22 and and CC cord-010398-5wot7tix 159 23 memory memory NN cord-010398-5wot7tix 159 24 difficulties difficulty NNS cord-010398-5wot7tix 159 25 ) ) -RRB- cord-010398-5wot7tix 159 26 occurred occur VBD cord-010398-5wot7tix 159 27 at at IN cord-010398-5wot7tix 159 28 a a DT cord-010398-5wot7tix 159 29 remarkably remarkably RB cord-010398-5wot7tix 159 30 similar similar JJ cord-010398-5wot7tix 159 31 rate rate NN cord-010398-5wot7tix 159 32 after after IN cord-010398-5wot7tix 159 33 each each DT cord-010398-5wot7tix 159 34 infection infection NN cord-010398-5wot7tix 159 35 . . . cord-010398-5wot7tix 160 1 Demographic demographic JJ cord-010398-5wot7tix 160 2 , , , cord-010398-5wot7tix 160 3 psychological psychological JJ cord-010398-5wot7tix 160 4 , , , cord-010398-5wot7tix 160 5 or or CC cord-010398-5wot7tix 160 6 microbiological microbiological JJ cord-010398-5wot7tix 160 7 factors factor NNS cord-010398-5wot7tix 160 8 during during IN cord-010398-5wot7tix 160 9 the the DT cord-010398-5wot7tix 160 10 acute acute JJ cord-010398-5wot7tix 160 11 infection infection NN cord-010398-5wot7tix 160 12 did do VBD cord-010398-5wot7tix 160 13 not not RB cord-010398-5wot7tix 160 14 predict predict VB cord-010398-5wot7tix 160 15 the the DT cord-010398-5wot7tix 160 16 development development NN cord-010398-5wot7tix 160 17 of of IN cord-010398-5wot7tix 160 18 this this DT cord-010398-5wot7tix 160 19 symptom symptom NN cord-010398-5wot7tix 160 20 complex complex NN cord-010398-5wot7tix 160 21 [ [ -LRB- cord-010398-5wot7tix 160 22 77 77 CD cord-010398-5wot7tix 160 23 ] ] -RRB- cord-010398-5wot7tix 160 24 . . . cord-010398-5wot7tix 161 1 None none NN cord-010398-5wot7tix 161 2 of of IN cord-010398-5wot7tix 161 3 the the DT cord-010398-5wot7tix 161 4 psychiatric psychiatric JJ cord-010398-5wot7tix 161 5 measurements measurement NNS cord-010398-5wot7tix 161 6 assessed assess VBN cord-010398-5wot7tix 161 7 in in IN cord-010398-5wot7tix 161 8 this this DT cord-010398-5wot7tix 161 9 study study NN cord-010398-5wot7tix 161 10 , , , cord-010398-5wot7tix 161 11 which which WDT cord-010398-5wot7tix 161 12 included include VBD cord-010398-5wot7tix 161 13 the the DT cord-010398-5wot7tix 161 14 presence presence NN cord-010398-5wot7tix 161 15 of of IN cord-010398-5wot7tix 161 16 a a DT cord-010398-5wot7tix 161 17 premorbid premorbid NN cord-010398-5wot7tix 161 18 or or CC cord-010398-5wot7tix 161 19 intercurrent intercurrent NN cord-010398-5wot7tix 161 20 psychiatric psychiatric JJ cord-010398-5wot7tix 161 21 disorder disorder NN cord-010398-5wot7tix 161 22 , , , cord-010398-5wot7tix 161 23 the the DT cord-010398-5wot7tix 161 24 neuroticism neuroticism NN cord-010398-5wot7tix 161 25 score score NN cord-010398-5wot7tix 161 26 , , , cord-010398-5wot7tix 161 27 and and CC cord-010398-5wot7tix 161 28 the the DT cord-010398-5wot7tix 161 29 locus locus NN cord-010398-5wot7tix 161 30 of of IN cord-010398-5wot7tix 161 31 control control NN cord-010398-5wot7tix 161 32 score score NN cord-010398-5wot7tix 161 33 , , , cord-010398-5wot7tix 161 34 was be VBD cord-010398-5wot7tix 161 35 significantly significantly RB cord-010398-5wot7tix 161 36 predictive predictive JJ cord-010398-5wot7tix 161 37 of of IN cord-010398-5wot7tix 161 38 the the DT cord-010398-5wot7tix 161 39 development development NN cord-010398-5wot7tix 161 40 of of IN cord-010398-5wot7tix 161 41 chronic chronic JJ cord-010398-5wot7tix 161 42 symptoms symptom NNS cord-010398-5wot7tix 161 43 . . . cord-010398-5wot7tix 162 1 As as IN cord-010398-5wot7tix 162 2 with with IN cord-010398-5wot7tix 162 3 the the DT cord-010398-5wot7tix 162 4 studies study NNS cord-010398-5wot7tix 162 5 of of IN cord-010398-5wot7tix 162 6 emotional emotional JJ cord-010398-5wot7tix 162 7 stress stress NN cord-010398-5wot7tix 162 8 triggering trigger VBG cord-010398-5wot7tix 162 9 pain pain NN cord-010398-5wot7tix 162 10 in in IN cord-010398-5wot7tix 162 11 the the DT cord-010398-5wot7tix 162 12 population population NN cord-010398-5wot7tix 162 13 , , , cord-010398-5wot7tix 162 14 although although IN cord-010398-5wot7tix 162 15 distress distress NN cord-010398-5wot7tix 162 16 per per FW cord-010398-5wot7tix 162 17 se se FW cord-010398-5wot7tix 162 18 did do VBD cord-010398-5wot7tix 162 19 not not RB cord-010398-5wot7tix 162 20 predict predict VB cord-010398-5wot7tix 162 21 the the DT cord-010398-5wot7tix 162 22 chronicity chronicity NN cord-010398-5wot7tix 162 23 of of IN cord-010398-5wot7tix 162 24 symptoms symptom NNS cord-010398-5wot7tix 162 25 after after IN cord-010398-5wot7tix 162 26 infection infection NN cord-010398-5wot7tix 162 27 , , , cord-010398-5wot7tix 162 28 the the DT cord-010398-5wot7tix 162 29 presence presence NN cord-010398-5wot7tix 162 30 and and CC cord-010398-5wot7tix 162 31 severity severity NN cord-010398-5wot7tix 162 32 of of IN cord-010398-5wot7tix 162 33 somatic somatic JJ cord-010398-5wot7tix 162 34 symptoms symptom NNS cord-010398-5wot7tix 162 35 ( ( -LRB- cord-010398-5wot7tix 162 36 ie ie FW cord-010398-5wot7tix 162 37 , , , cord-010398-5wot7tix 162 38 the the DT cord-010398-5wot7tix 162 39 degree degree NN cord-010398-5wot7tix 162 40 of of IN cord-010398-5wot7tix 162 41 " " `` cord-010398-5wot7tix 162 42 somatization somatization NN cord-010398-5wot7tix 162 43 " " '' cord-010398-5wot7tix 162 44 ) ) -RRB- cord-010398-5wot7tix 162 45 during during IN cord-010398-5wot7tix 162 46 the the DT cord-010398-5wot7tix 162 47 acute acute JJ cord-010398-5wot7tix 162 48 infection infection NN cord-010398-5wot7tix 162 49 was be VBD cord-010398-5wot7tix 162 50 closely closely RB cord-010398-5wot7tix 162 51 correlated correlate VBN cord-010398-5wot7tix 162 52 with with IN cord-010398-5wot7tix 162 53 the the DT cord-010398-5wot7tix 162 54 subsequent subsequent JJ cord-010398-5wot7tix 162 55 development development NN cord-010398-5wot7tix 162 56 of of IN cord-010398-5wot7tix 162 57 chronic chronic JJ cord-010398-5wot7tix 162 58 fatigue fatigue NN cord-010398-5wot7tix 162 59 ( ( -LRB- cord-010398-5wot7tix 162 60 and and CC cord-010398-5wot7tix 162 61 pain pain NN cord-010398-5wot7tix 162 62 ) ) -RRB- cord-010398-5wot7tix 162 63 . . . cord-010398-5wot7tix 163 1 The the DT cord-010398-5wot7tix 163 2 relationship relationship NN cord-010398-5wot7tix 163 3 between between IN cord-010398-5wot7tix 163 4 acute acute JJ cord-010398-5wot7tix 163 5 infection infection NN cord-010398-5wot7tix 163 6 and and CC cord-010398-5wot7tix 163 7 the the DT cord-010398-5wot7tix 163 8 development development NN cord-010398-5wot7tix 163 9 of of IN cord-010398-5wot7tix 163 10 chronic chronic JJ cord-010398-5wot7tix 163 11 regional regional JJ cord-010398-5wot7tix 163 12 pain pain NN cord-010398-5wot7tix 163 13 and and CC cord-010398-5wot7tix 163 14 other other JJ cord-010398-5wot7tix 163 15 somatic somatic JJ cord-010398-5wot7tix 163 16 symptoms symptom NNS cord-010398-5wot7tix 163 17 has have VBZ cord-010398-5wot7tix 163 18 been be VBN cord-010398-5wot7tix 163 19 noted note VBN cord-010398-5wot7tix 163 20 in in IN cord-010398-5wot7tix 163 21 a a DT cord-010398-5wot7tix 163 22 number number NN cord-010398-5wot7tix 163 23 of of IN cord-010398-5wot7tix 163 24 other other JJ cord-010398-5wot7tix 163 25 conditions condition NNS cord-010398-5wot7tix 163 26 related relate VBN cord-010398-5wot7tix 163 27 to to IN cord-010398-5wot7tix 163 28 FM FM NNP cord-010398-5wot7tix 163 29 . . . cord-010398-5wot7tix 164 1 For for IN cord-010398-5wot7tix 164 2 example example NN cord-010398-5wot7tix 164 3 , , , cord-010398-5wot7tix 164 4 in in IN cord-010398-5wot7tix 164 5 a a DT cord-010398-5wot7tix 164 6 meta meta JJ cord-010398-5wot7tix 164 7 - - HYPH cord-010398-5wot7tix 164 8 analysis analysis NN cord-010398-5wot7tix 164 9 summarizing summarize VBG cord-010398-5wot7tix 164 10 the the DT cord-010398-5wot7tix 164 11 results result NNS cord-010398-5wot7tix 164 12 of of IN cord-010398-5wot7tix 164 13 8 8 CD cord-010398-5wot7tix 164 14 different different JJ cord-010398-5wot7tix 164 15 studies study NNS cord-010398-5wot7tix 164 16 , , , cord-010398-5wot7tix 164 17 Halvorson Halvorson NNP cord-010398-5wot7tix 164 18 et et NNP cord-010398-5wot7tix 164 19 al al NNP cord-010398-5wot7tix 164 20 [ [ -LRB- cord-010398-5wot7tix 164 21 78 78 CD cord-010398-5wot7tix 164 22 ] ] -RRB- cord-010398-5wot7tix 164 23 noted note VBD cord-010398-5wot7tix 164 24 that that IN cord-010398-5wot7tix 164 25 approximately approximately RB cord-010398-5wot7tix 164 26 10 10 CD cord-010398-5wot7tix 164 27 % % NN cord-010398-5wot7tix 164 28 of of IN cord-010398-5wot7tix 164 29 patients patient NNS cord-010398-5wot7tix 164 30 developed develop VBN cord-010398-5wot7tix 164 31 postinfectious postinfectious JJ cord-010398-5wot7tix 164 32 IBS IBS NNP cord-010398-5wot7tix 164 33 after after IN cord-010398-5wot7tix 164 34 an an DT cord-010398-5wot7tix 164 35 episode episode NN cord-010398-5wot7tix 164 36 of of IN cord-010398-5wot7tix 164 37 acute acute JJ cord-010398-5wot7tix 164 38 infectious infectious JJ cord-010398-5wot7tix 164 39 gastroenteritis gastroenteritis NN cord-010398-5wot7tix 164 40 , , , cord-010398-5wot7tix 164 41 regardless regardless RB cord-010398-5wot7tix 164 42 of of IN cord-010398-5wot7tix 164 43 the the DT cord-010398-5wot7tix 164 44 viral viral JJ cord-010398-5wot7tix 164 45 or or CC cord-010398-5wot7tix 164 46 bacterial bacterial JJ cord-010398-5wot7tix 164 47 pathogen pathogen NN cord-010398-5wot7tix 164 48 that that WDT cord-010398-5wot7tix 164 49 caused cause VBD cord-010398-5wot7tix 164 50 the the DT cord-010398-5wot7tix 164 51 acute acute JJ cord-010398-5wot7tix 164 52 illness illness NN cord-010398-5wot7tix 164 53 . . . cord-010398-5wot7tix 165 1 Similarly similarly RB cord-010398-5wot7tix 165 2 , , , cord-010398-5wot7tix 165 3 an an DT cord-010398-5wot7tix 165 4 episode episode NN cord-010398-5wot7tix 165 5 of of IN cord-010398-5wot7tix 165 6 acute acute JJ cord-010398-5wot7tix 165 7 urinary urinary JJ cord-010398-5wot7tix 165 8 tract tract NN cord-010398-5wot7tix 165 9 infection infection NN cord-010398-5wot7tix 165 10 is be VBZ cord-010398-5wot7tix 165 11 evident evident JJ cord-010398-5wot7tix 165 12 in in IN cord-010398-5wot7tix 165 13 a a DT cord-010398-5wot7tix 165 14 proportion proportion NN cord-010398-5wot7tix 165 15 of of IN cord-010398-5wot7tix 165 16 women woman NNS cord-010398-5wot7tix 165 17 who who WP cord-010398-5wot7tix 165 18 develop develop VBP cord-010398-5wot7tix 165 19 interstitial interstitial JJ cord-010398-5wot7tix 165 20 cystitis cystitis NN cord-010398-5wot7tix 165 21 / / SYM cord-010398-5wot7tix 165 22 painful painful JJ cord-010398-5wot7tix 165 23 bladder bladder NN cord-010398-5wot7tix 165 24 syndrome syndrome NN cord-010398-5wot7tix 165 25 . . . cord-010398-5wot7tix 166 1 In in IN cord-010398-5wot7tix 166 2 fact fact NN cord-010398-5wot7tix 166 3 , , , cord-010398-5wot7tix 166 4 in in IN cord-010398-5wot7tix 166 5 a a DT cord-010398-5wot7tix 166 6 recent recent JJ cord-010398-5wot7tix 166 7 study study NN cord-010398-5wot7tix 166 8 , , , cord-010398-5wot7tix 166 9 Hamilton Hamilton NNP cord-010398-5wot7tix 166 10 and and CC cord-010398-5wot7tix 166 11 associates associate NNS cord-010398-5wot7tix 166 12 [ [ -LRB- cord-010398-5wot7tix 166 13 79 79 CD cord-010398-5wot7tix 166 14 ] ] -RRB- cord-010398-5wot7tix 166 15 , , , cord-010398-5wot7tix 166 16 who who WP cord-010398-5wot7tix 166 17 were be VBD cord-010398-5wot7tix 166 18 among among IN cord-010398-5wot7tix 166 19 the the DT cord-010398-5wot7tix 166 20 first first JJ cord-010398-5wot7tix 166 21 to to TO cord-010398-5wot7tix 166 22 investigate investigate VB cord-010398-5wot7tix 166 23 this this DT cord-010398-5wot7tix 166 24 issue issue NN cord-010398-5wot7tix 166 25 across across IN cord-010398-5wot7tix 166 26 syndromes syndrome NNS cord-010398-5wot7tix 166 27 , , , cord-010398-5wot7tix 166 28 found find VBD cord-010398-5wot7tix 166 29 that that IN cord-010398-5wot7tix 166 30 episodes episode NNS cord-010398-5wot7tix 166 31 of of IN cord-010398-5wot7tix 166 32 gastroenteritis gastroenteritis NN cord-010398-5wot7tix 166 33 in in IN cord-010398-5wot7tix 166 34 diagnosed diagnose VBN cord-010398-5wot7tix 166 35 in in IN cord-010398-5wot7tix 166 36 primary primary JJ cord-010398-5wot7tix 166 37 care care NN cord-010398-5wot7tix 166 38 were be VBD cord-010398-5wot7tix 166 39 risk risk NN cord-010398-5wot7tix 166 40 factors factor NNS cord-010398-5wot7tix 166 41 for for IN cord-010398-5wot7tix 166 42 IBS IBS NNP cord-010398-5wot7tix 166 43 , , , cord-010398-5wot7tix 166 44 whereas whereas IN cord-010398-5wot7tix 166 45 viral viral JJ cord-010398-5wot7tix 166 46 infections infection NNS cord-010398-5wot7tix 166 47 increased increase VBD cord-010398-5wot7tix 166 48 the the DT cord-010398-5wot7tix 166 49 risk risk NN cord-010398-5wot7tix 166 50 for for IN cord-010398-5wot7tix 166 51 subsequent subsequent JJ cord-010398-5wot7tix 166 52 development development NN cord-010398-5wot7tix 166 53 of of IN cord-010398-5wot7tix 166 54 CFS CFS NNP cord-010398-5wot7tix 166 55 . . . cord-010398-5wot7tix 167 1 They -PRON- PRP cord-010398-5wot7tix 167 2 again again RB cord-010398-5wot7tix 167 3 found find VBD cord-010398-5wot7tix 167 4 that that IN cord-010398-5wot7tix 167 5 premorbid premorbid NN cord-010398-5wot7tix 167 6 psychiatric psychiatric JJ cord-010398-5wot7tix 167 7 disorders disorder NNS cord-010398-5wot7tix 167 8 such such JJ cord-010398-5wot7tix 167 9 as as IN cord-010398-5wot7tix 167 10 depression depression NN cord-010398-5wot7tix 167 11 only only RB cord-010398-5wot7tix 167 12 modestly modestly RB cord-010398-5wot7tix 167 13 increased increase VBD cord-010398-5wot7tix 167 14 the the DT cord-010398-5wot7tix 167 15 risk risk NN cord-010398-5wot7tix 167 16 of of IN cord-010398-5wot7tix 167 17 this this DT cord-010398-5wot7tix 167 18 occurring occurring NN cord-010398-5wot7tix 167 19 . . . cord-010398-5wot7tix 168 1 These these DT cord-010398-5wot7tix 168 2 results result NNS cord-010398-5wot7tix 168 3 imply imply VBP cord-010398-5wot7tix 168 4 that that IN cord-010398-5wot7tix 168 5 various various JJ cord-010398-5wot7tix 168 6 forms form NNS cord-010398-5wot7tix 168 7 of of IN cord-010398-5wot7tix 168 8 acute acute JJ cord-010398-5wot7tix 168 9 infection infection NN cord-010398-5wot7tix 168 10 are be VBP cord-010398-5wot7tix 168 11 capable capable JJ cord-010398-5wot7tix 168 12 of of IN cord-010398-5wot7tix 168 13 triggering trigger VBG cord-010398-5wot7tix 168 14 syndromes syndrome NNS cord-010398-5wot7tix 168 15 such such JJ cord-010398-5wot7tix 168 16 as as IN cord-010398-5wot7tix 168 17 CFS CFS NNP cord-010398-5wot7tix 168 18 and and CC cord-010398-5wot7tix 168 19 FM FM NNP cord-010398-5wot7tix 168 20 , , , cord-010398-5wot7tix 168 21 with with IN cord-010398-5wot7tix 168 22 multifocal multifocal JJ cord-010398-5wot7tix 168 23 or or CC cord-010398-5wot7tix 168 24 regional regional JJ cord-010398-5wot7tix 168 25 pain pain NN cord-010398-5wot7tix 168 26 ; ; : cord-010398-5wot7tix 168 27 chronic chronic JJ cord-010398-5wot7tix 168 28 pain pain NN cord-010398-5wot7tix 168 29 most most RBS cord-010398-5wot7tix 168 30 typically typically RB cord-010398-5wot7tix 168 31 occurs occur VBZ cord-010398-5wot7tix 168 32 in in IN cord-010398-5wot7tix 168 33 the the DT cord-010398-5wot7tix 168 34 body body NN cord-010398-5wot7tix 168 35 region region NN cord-010398-5wot7tix 168 36 initially initially RB cord-010398-5wot7tix 168 37 affected affect VBN cord-010398-5wot7tix 168 38 by by IN cord-010398-5wot7tix 168 39 the the DT cord-010398-5wot7tix 168 40 infection infection NN cord-010398-5wot7tix 168 41 . . . cord-010398-5wot7tix 169 1 There there EX cord-010398-5wot7tix 169 2 are be VBP cord-010398-5wot7tix 169 3 often often RB cord-010398-5wot7tix 169 4 accompanying accompany VBG cord-010398-5wot7tix 169 5 somatic somatic JJ cord-010398-5wot7tix 169 6 symptoms symptom NNS cord-010398-5wot7tix 169 7 such such JJ cord-010398-5wot7tix 169 8 as as IN cord-010398-5wot7tix 169 9 fatigue fatigue NN cord-010398-5wot7tix 169 10 , , , cord-010398-5wot7tix 169 11 memory memory NN cord-010398-5wot7tix 169 12 , , , cord-010398-5wot7tix 169 13 and and CC cord-010398-5wot7tix 169 14 mood mood NN cord-010398-5wot7tix 169 15 difficulties difficulty NNS cord-010398-5wot7tix 169 16 . . . cord-010398-5wot7tix 170 1 The the DT cord-010398-5wot7tix 170 2 risk risk NN cord-010398-5wot7tix 170 3 of of IN cord-010398-5wot7tix 170 4 this this DT cord-010398-5wot7tix 170 5 symptom symptom NN cord-010398-5wot7tix 170 6 complex complex NN cord-010398-5wot7tix 170 7 occurring occur VBG cord-010398-5wot7tix 170 8 with with IN cord-010398-5wot7tix 170 9 various various JJ cord-010398-5wot7tix 170 10 infections infection NNS cord-010398-5wot7tix 170 11 is be VBZ cord-010398-5wot7tix 170 12 consistently consistently RB cord-010398-5wot7tix 170 13 found find VBN cord-010398-5wot7tix 170 14 to to TO cord-010398-5wot7tix 170 15 be be VB cord-010398-5wot7tix 170 16 approximately approximately RB cord-010398-5wot7tix 170 17 5 5 CD cord-010398-5wot7tix 170 18 % % NN cord-010398-5wot7tix 170 19 to to TO cord-010398-5wot7tix 170 20 10 10 CD cord-010398-5wot7tix 170 21 % % NN cord-010398-5wot7tix 170 22 . . . cord-010398-5wot7tix 171 1 The the DT cord-010398-5wot7tix 171 2 reason reason NN cord-010398-5wot7tix 171 3 for for IN cord-010398-5wot7tix 171 4 this this DT cord-010398-5wot7tix 171 5 consistency consistency NN cord-010398-5wot7tix 171 6 is be VBZ cord-010398-5wot7tix 171 7 not not RB cord-010398-5wot7tix 171 8 clear clear JJ cord-010398-5wot7tix 171 9 . . . cord-010398-5wot7tix 172 1 Evidently evidently RB cord-010398-5wot7tix 172 2 , , , cord-010398-5wot7tix 172 3 the the DT cord-010398-5wot7tix 172 4 inciting incite VBG cord-010398-5wot7tix 172 5 infection infection NN cord-010398-5wot7tix 172 6 must must MD cord-010398-5wot7tix 172 7 be be VB cord-010398-5wot7tix 172 8 of of IN cord-010398-5wot7tix 172 9 sufficient sufficient JJ cord-010398-5wot7tix 172 10 severity severity NN cord-010398-5wot7tix 172 11 and and CC cord-010398-5wot7tix 172 12 duration duration NN cord-010398-5wot7tix 172 13 because because IN cord-010398-5wot7tix 172 14 the the DT cord-010398-5wot7tix 172 15 increase increase NN cord-010398-5wot7tix 172 16 in in IN cord-010398-5wot7tix 172 17 occurrence occurrence NN cord-010398-5wot7tix 172 18 of of IN cord-010398-5wot7tix 172 19 chronic chronic JJ cord-010398-5wot7tix 172 20 symptoms symptom NNS cord-010398-5wot7tix 172 21 is be VBZ cord-010398-5wot7tix 172 22 not not RB cord-010398-5wot7tix 172 23 observed observe VBN cord-010398-5wot7tix 172 24 after after IN cord-010398-5wot7tix 172 25 common common JJ cord-010398-5wot7tix 172 26 viral viral JJ cord-010398-5wot7tix 172 27 infections infection NNS cord-010398-5wot7tix 172 28 of of IN cord-010398-5wot7tix 172 29 short short JJ cord-010398-5wot7tix 172 30 duration duration NN cord-010398-5wot7tix 172 31 . . . cord-010398-5wot7tix 173 1 This this DT cord-010398-5wot7tix 173 2 lack lack NN cord-010398-5wot7tix 173 3 of of IN cord-010398-5wot7tix 173 4 specificity specificity NN cord-010398-5wot7tix 173 5 regarding regard VBG cord-010398-5wot7tix 173 6 the the DT cord-010398-5wot7tix 173 7 triggering trigger VBG cord-010398-5wot7tix 173 8 effect effect NN cord-010398-5wot7tix 173 9 of of IN cord-010398-5wot7tix 173 10 infection infection NN cord-010398-5wot7tix 173 11 may may MD cord-010398-5wot7tix 173 12 well well RB cord-010398-5wot7tix 173 13 be be VB cord-010398-5wot7tix 173 14 associated associate VBN cord-010398-5wot7tix 173 15 with with IN cord-010398-5wot7tix 173 16 an an DT cord-010398-5wot7tix 173 17 underlying underlying JJ cord-010398-5wot7tix 173 18 genetic genetic JJ cord-010398-5wot7tix 173 19 predisposition predisposition NN cord-010398-5wot7tix 173 20 , , , cord-010398-5wot7tix 173 21 activated activate VBN cord-010398-5wot7tix 173 22 in in IN cord-010398-5wot7tix 173 23 a a DT cord-010398-5wot7tix 173 24 similar similar JJ cord-010398-5wot7tix 173 25 manner manner NN cord-010398-5wot7tix 173 26 by by IN cord-010398-5wot7tix 173 27 various various JJ cord-010398-5wot7tix 173 28 pathogens pathogen NNS cord-010398-5wot7tix 173 29 , , , cord-010398-5wot7tix 173 30 and/or and/or CC cord-010398-5wot7tix 173 31 in in IN cord-010398-5wot7tix 173 32 patients patient NNS cord-010398-5wot7tix 173 33 with with IN cord-010398-5wot7tix 173 34 a a DT cord-010398-5wot7tix 173 35 set set NN cord-010398-5wot7tix 173 36 of of IN cord-010398-5wot7tix 173 37 " " `` cord-010398-5wot7tix 173 38 maladaptive maladaptive JJ cord-010398-5wot7tix 173 39 " " '' cord-010398-5wot7tix 173 40 behavioral behavioral JJ cord-010398-5wot7tix 173 41 responses response NNS cord-010398-5wot7tix 173 42 that that WDT cord-010398-5wot7tix 173 43 could could MD cord-010398-5wot7tix 173 44 lead lead VB cord-010398-5wot7tix 173 45 to to IN cord-010398-5wot7tix 173 46 symptoms symptom NNS cord-010398-5wot7tix 173 47 , , , cord-010398-5wot7tix 173 48 such such JJ cord-010398-5wot7tix 173 49 as as IN cord-010398-5wot7tix 173 50 cessation cessation NN cord-010398-5wot7tix 173 51 of of IN cord-010398-5wot7tix 173 52 routine routine JJ cord-010398-5wot7tix 173 53 exercise exercise NN cord-010398-5wot7tix 173 54 or or CC cord-010398-5wot7tix 173 55 sleep sleep NN cord-010398-5wot7tix 173 56 . . . cord-010398-5wot7tix 174 1 At at IN cord-010398-5wot7tix 174 2 present present JJ cord-010398-5wot7tix 174 3 , , , cord-010398-5wot7tix 174 4 there there EX cord-010398-5wot7tix 174 5 is be VBZ cord-010398-5wot7tix 174 6 one one CD cord-010398-5wot7tix 174 7 active active JJ cord-010398-5wot7tix 174 8 research research NN cord-010398-5wot7tix 174 9 area area NN cord-010398-5wot7tix 174 10 of of IN cord-010398-5wot7tix 174 11 investigation investigation NN cord-010398-5wot7tix 174 12 focused focus VBD cord-010398-5wot7tix 174 13 on on IN cord-010398-5wot7tix 174 14 a a DT cord-010398-5wot7tix 174 15 potential potential JJ cord-010398-5wot7tix 174 16 infection infection NN cord-010398-5wot7tix 174 17 that that WDT cord-010398-5wot7tix 174 18 may may MD cord-010398-5wot7tix 174 19 be be VB cord-010398-5wot7tix 174 20 causing cause VBG cord-010398-5wot7tix 174 21 CFS cfs NN cord-010398-5wot7tix 174 22 : : : cord-010398-5wot7tix 174 23 the the DT cord-010398-5wot7tix 174 24 XMRV XMRV NNP cord-010398-5wot7tix 174 25 virus virus NN cord-010398-5wot7tix 174 26 [ [ -LRB- cord-010398-5wot7tix 174 27 80 80 CD cord-010398-5wot7tix 174 28 ] ] -RRB- cord-010398-5wot7tix 174 29 . . . cord-010398-5wot7tix 175 1 Although although IN cord-010398-5wot7tix 175 2 the the DT cord-010398-5wot7tix 175 3 study study NN cord-010398-5wot7tix 175 4 demonstrating demonstrate VBG cord-010398-5wot7tix 175 5 both both CC cord-010398-5wot7tix 175 6 antibody antibody NN cord-010398-5wot7tix 175 7 and and CC cord-010398-5wot7tix 175 8 culture culture NN cord-010398-5wot7tix 175 9 evidence evidence NN cord-010398-5wot7tix 175 10 of of IN cord-010398-5wot7tix 175 11 this this DT cord-010398-5wot7tix 175 12 virus virus NN cord-010398-5wot7tix 175 13 in in IN cord-010398-5wot7tix 175 14 a a DT cord-010398-5wot7tix 175 15 high high JJ cord-010398-5wot7tix 175 16 proportion proportion NN cord-010398-5wot7tix 175 17 of of IN cord-010398-5wot7tix 175 18 CFS cfs NN cord-010398-5wot7tix 175 19 patients patient NNS cord-010398-5wot7tix 175 20 was be VBD cord-010398-5wot7tix 175 21 methodologically methodologically RB cord-010398-5wot7tix 175 22 sound sound JJ cord-010398-5wot7tix 175 23 , , , cord-010398-5wot7tix 175 24 albeit albeit IN cord-010398-5wot7tix 175 25 with with IN cord-010398-5wot7tix 175 26 very very RB cord-010398-5wot7tix 175 27 few few JJ cord-010398-5wot7tix 175 28 controls control NNS cord-010398-5wot7tix 175 29 , , , cord-010398-5wot7tix 175 30 this this DT cord-010398-5wot7tix 175 31 field field NN cord-010398-5wot7tix 175 32 has have VBZ cord-010398-5wot7tix 175 33 " " `` cord-010398-5wot7tix 175 34 been be VBN cord-010398-5wot7tix 175 35 here here RB cord-010398-5wot7tix 175 36 " " '' cord-010398-5wot7tix 175 37 repeatedly repeatedly RB cord-010398-5wot7tix 175 38 . . . cord-010398-5wot7tix 176 1 These these DT cord-010398-5wot7tix 176 2 results result NNS cord-010398-5wot7tix 176 3 need need VBP cord-010398-5wot7tix 176 4 to to TO cord-010398-5wot7tix 176 5 be be VB cord-010398-5wot7tix 176 6 replicated replicate VBN cord-010398-5wot7tix 176 7 by by IN cord-010398-5wot7tix 176 8 another another DT cord-010398-5wot7tix 176 9 group group NN cord-010398-5wot7tix 176 10 because because IN cord-010398-5wot7tix 176 11 the the DT cord-010398-5wot7tix 176 12 institute institute NN cord-010398-5wot7tix 176 13 that that WDT cord-010398-5wot7tix 176 14 performed perform VBD cord-010398-5wot7tix 176 15 this this DT cord-010398-5wot7tix 176 16 study study NN cord-010398-5wot7tix 176 17 was be VBD cord-010398-5wot7tix 176 18 ostensibly ostensibly RB cord-010398-5wot7tix 176 19 created create VBN cord-010398-5wot7tix 176 20 to to TO cord-010398-5wot7tix 176 21 identify identify VB cord-010398-5wot7tix 176 22 the the DT cord-010398-5wot7tix 176 23 infectious infectious JJ cord-010398-5wot7tix 176 24 or or CC cord-010398-5wot7tix 176 25 immune immune JJ cord-010398-5wot7tix 176 26 underpinnings underpinning NNS cord-010398-5wot7tix 176 27 to to IN cord-010398-5wot7tix 176 28 CFS CFS NNP cord-010398-5wot7tix 176 29 , , , cord-010398-5wot7tix 176 30 and and CC cord-010398-5wot7tix 176 31 then then RB cord-010398-5wot7tix 176 32 longitudinal longitudinal JJ cord-010398-5wot7tix 176 33 studies study NNS cord-010398-5wot7tix 176 34 need need VBP cord-010398-5wot7tix 176 35 to to TO cord-010398-5wot7tix 176 36 demonstrate demonstrate VB cord-010398-5wot7tix 176 37 causality causality NN cord-010398-5wot7tix 176 38 rather rather RB cord-010398-5wot7tix 176 39 than than IN cord-010398-5wot7tix 176 40 association association NN cord-010398-5wot7tix 176 41 , , , cord-010398-5wot7tix 176 42 as as IN cord-010398-5wot7tix 176 43 we -PRON- PRP cord-010398-5wot7tix 176 44 have have VBP cord-010398-5wot7tix 176 45 learned learn VBN cord-010398-5wot7tix 176 46 from from IN cord-010398-5wot7tix 176 47 previous previous JJ cord-010398-5wot7tix 176 48 studies study NNS cord-010398-5wot7tix 176 49 in in IN cord-010398-5wot7tix 176 50 CFS CFS NNP cord-010398-5wot7tix 176 51 . . . cord-010398-5wot7tix 177 1 There there EX cord-010398-5wot7tix 177 2 is be VBZ cord-010398-5wot7tix 177 3 an an DT cord-010398-5wot7tix 177 4 expansive expansive JJ cord-010398-5wot7tix 177 5 literature literature NN cord-010398-5wot7tix 177 6 on on IN cord-010398-5wot7tix 177 7 this this DT cord-010398-5wot7tix 177 8 topic topic NN cord-010398-5wot7tix 177 9 , , , cord-010398-5wot7tix 177 10 with with IN cord-010398-5wot7tix 177 11 the the DT cord-010398-5wot7tix 177 12 authors author NNS cord-010398-5wot7tix 177 13 of of IN cord-010398-5wot7tix 177 14 many many JJ cord-010398-5wot7tix 177 15 studies study NNS cord-010398-5wot7tix 177 16 identifying identify VBG cord-010398-5wot7tix 177 17 differences difference NNS cord-010398-5wot7tix 177 18 in in IN cord-010398-5wot7tix 177 19 cytokine cytokine NN cord-010398-5wot7tix 177 20 levels level NNS cord-010398-5wot7tix 177 21 in in IN cord-010398-5wot7tix 177 22 CFS cfs NN cord-010398-5wot7tix 177 23 populations population NNS cord-010398-5wot7tix 177 24 ( ( -LRB- cord-010398-5wot7tix 177 25 usually usually RB cord-010398-5wot7tix 177 26 in in IN cord-010398-5wot7tix 177 27 highly highly RB cord-010398-5wot7tix 177 28 selected selected JJ cord-010398-5wot7tix 177 29 tertiary tertiary JJ cord-010398-5wot7tix 177 30 care care NN cord-010398-5wot7tix 177 31 patients patient NNS cord-010398-5wot7tix 177 32 ) ) -RRB- cord-010398-5wot7tix 177 33 and and CC cord-010398-5wot7tix 177 34 others other NNS cord-010398-5wot7tix 177 35 finding find VBG cord-010398-5wot7tix 177 36 normal normal JJ cord-010398-5wot7tix 177 37 levels level NNS cord-010398-5wot7tix 177 38 . . . cord-010398-5wot7tix 178 1 Antoni Antoni NNP cord-010398-5wot7tix 178 2 , , , cord-010398-5wot7tix 178 3 Klimas Klimas NNP cord-010398-5wot7tix 178 4 , , , cord-010398-5wot7tix 178 5 and and CC cord-010398-5wot7tix 178 6 colleagues colleague NNS cord-010398-5wot7tix 178 7 [ [ -LRB- cord-010398-5wot7tix 178 8 81 81 CD cord-010398-5wot7tix 178 9 ] ] -RRB- cord-010398-5wot7tix 178 10 have have VBP cord-010398-5wot7tix 178 11 arguably arguably RB cord-010398-5wot7tix 178 12 been be VBN cord-010398-5wot7tix 178 13 the the DT cord-010398-5wot7tix 178 14 most most RBS cord-010398-5wot7tix 178 15 active active JJ cord-010398-5wot7tix 178 16 group group NN cord-010398-5wot7tix 178 17 studying study VBG cord-010398-5wot7tix 178 18 subsets subset NNS cord-010398-5wot7tix 178 19 of of IN cord-010398-5wot7tix 178 20 CFS cfs NN cord-010398-5wot7tix 178 21 patients patient NNS cord-010398-5wot7tix 178 22 with with IN cord-010398-5wot7tix 178 23 elevated elevated JJ cord-010398-5wot7tix 178 24 levels level NNS cord-010398-5wot7tix 178 25 of of IN cord-010398-5wot7tix 178 26 cytokines cytokine NNS cord-010398-5wot7tix 178 27 , , , cord-010398-5wot7tix 178 28 and and CC cord-010398-5wot7tix 178 29 they -PRON- PRP cord-010398-5wot7tix 178 30 have have VBP cord-010398-5wot7tix 178 31 shown show VBN cord-010398-5wot7tix 178 32 that that IN cord-010398-5wot7tix 178 33 some some DT cord-010398-5wot7tix 178 34 but but CC cord-010398-5wot7tix 178 35 not not RB cord-010398-5wot7tix 178 36 all all DT cord-010398-5wot7tix 178 37 cytokines cytokine NNS cord-010398-5wot7tix 178 38 are be VBP cord-010398-5wot7tix 178 39 elevated elevate VBN cord-010398-5wot7tix 178 40 in in IN cord-010398-5wot7tix 178 41 their -PRON- PRP$ cord-010398-5wot7tix 178 42 cohort cohort NN cord-010398-5wot7tix 178 43 of of IN cord-010398-5wot7tix 178 44 CFS CFS NNP cord-010398-5wot7tix 178 45 patients patient NNS cord-010398-5wot7tix 178 46 compared compare VBN cord-010398-5wot7tix 178 47 with with IN cord-010398-5wot7tix 178 48 control control NN cord-010398-5wot7tix 178 49 patients patient NNS cord-010398-5wot7tix 178 50 . . . cord-010398-5wot7tix 179 1 However however RB cord-010398-5wot7tix 179 2 , , , cord-010398-5wot7tix 179 3 other other JJ cord-010398-5wot7tix 179 4 groups group NNS cord-010398-5wot7tix 179 5 have have VBP cord-010398-5wot7tix 179 6 recently recently RB cord-010398-5wot7tix 179 7 published publish VBN cord-010398-5wot7tix 179 8 studies study NNS cord-010398-5wot7tix 179 9 in in IN cord-010398-5wot7tix 179 10 which which WDT cord-010398-5wot7tix 179 11 there there EX cord-010398-5wot7tix 179 12 was be VBD cord-010398-5wot7tix 179 13 superior superior JJ cord-010398-5wot7tix 179 14 methodology methodology NN cord-010398-5wot7tix 179 15 , , , cord-010398-5wot7tix 179 16 including include VBG cord-010398-5wot7tix 179 17 matching matching NN cord-010398-5wot7tix 179 18 of of IN cord-010398-5wot7tix 179 19 case case NN cord-010398-5wot7tix 179 20 and and CC cord-010398-5wot7tix 179 21 control control NN cord-010398-5wot7tix 179 22 subjects subject NNS cord-010398-5wot7tix 179 23 , , , cord-010398-5wot7tix 179 24 such such JJ cord-010398-5wot7tix 179 25 as as IN cord-010398-5wot7tix 179 26 with with IN cord-010398-5wot7tix 179 27 population population NN cord-010398-5wot7tix 179 28 - - HYPH cord-010398-5wot7tix 179 29 based base VBN cord-010398-5wot7tix 179 30 approaches approach NNS cord-010398-5wot7tix 179 31 , , , cord-010398-5wot7tix 179 32 or or CC cord-010398-5wot7tix 179 33 twin twin JJ cord-010398-5wot7tix 179 34 studies study NNS cord-010398-5wot7tix 179 35 . . . cord-010398-5wot7tix 180 1 These these DT cord-010398-5wot7tix 180 2 studies study NNS cord-010398-5wot7tix 180 3 failed fail VBD cord-010398-5wot7tix 180 4 to to TO cord-010398-5wot7tix 180 5 find find VB cord-010398-5wot7tix 180 6 any any DT cord-010398-5wot7tix 180 7 specific specific JJ cord-010398-5wot7tix 180 8 differences difference NNS cord-010398-5wot7tix 180 9 between between IN cord-010398-5wot7tix 180 10 CFS cfs NN cord-010398-5wot7tix 180 11 patient patient NN cord-010398-5wot7tix 180 12 and and CC cord-010398-5wot7tix 180 13 control control NN cord-010398-5wot7tix 180 14 subjects subject NNS cord-010398-5wot7tix 180 15 , , , cord-010398-5wot7tix 180 16 but but CC cord-010398-5wot7tix 180 17 the the DT cord-010398-5wot7tix 180 18 population population NN cord-010398-5wot7tix 180 19 - - HYPH cord-010398-5wot7tix 180 20 based base VBN cord-010398-5wot7tix 180 21 studies study NNS cord-010398-5wot7tix 180 22 do do VBP cord-010398-5wot7tix 180 23 show show VB cord-010398-5wot7tix 180 24 that that IN cord-010398-5wot7tix 180 25 inflammation inflammation NN cord-010398-5wot7tix 180 26 is be VBZ cord-010398-5wot7tix 180 27 a a DT cord-010398-5wot7tix 180 28 nonspecific nonspecific JJ cord-010398-5wot7tix 180 29 finding finding NN cord-010398-5wot7tix 180 30 in in IN cord-010398-5wot7tix 180 31 patients patient NNS cord-010398-5wot7tix 180 32 with with IN cord-010398-5wot7tix 180 33 " " `` cord-010398-5wot7tix 180 34 unwellness unwellness NN cord-010398-5wot7tix 180 35 " " '' cord-010398-5wot7tix 180 36 and and CC cord-010398-5wot7tix 180 37 is be VBZ cord-010398-5wot7tix 180 38 also also RB cord-010398-5wot7tix 180 39 affected affect VBN cord-010398-5wot7tix 180 40 by by IN cord-010398-5wot7tix 180 41 conditions condition NNS cord-010398-5wot7tix 180 42 such such JJ cord-010398-5wot7tix 180 43 as as IN cord-010398-5wot7tix 180 44 obesity obesity NN cord-010398-5wot7tix 180 45 [ [ -LRB- cord-010398-5wot7tix 180 46 5 5 CD cord-010398-5wot7tix 180 47 , , , cord-010398-5wot7tix 180 48 82 82 CD cord-010398-5wot7tix 180 49 ] ] -RRB- cord-010398-5wot7tix 180 50 . . . cord-010398-5wot7tix 181 1 In in IN cord-010398-5wot7tix 181 2 addition addition NN cord-010398-5wot7tix 181 3 , , , cord-010398-5wot7tix 181 4 recent recent JJ cord-010398-5wot7tix 181 5 findings finding NNS cord-010398-5wot7tix 181 6 regarding regard VBG cord-010398-5wot7tix 181 7 the the DT cord-010398-5wot7tix 181 8 role role NN cord-010398-5wot7tix 181 9 of of IN cord-010398-5wot7tix 181 10 glial glial JJ cord-010398-5wot7tix 181 11 cells cell NNS cord-010398-5wot7tix 181 12 , , , cord-010398-5wot7tix 181 13 astrocytes astrocyte NNS cord-010398-5wot7tix 181 14 , , , cord-010398-5wot7tix 181 15 and and CC cord-010398-5wot7tix 181 16 other other JJ cord-010398-5wot7tix 181 17 neural neural JJ cord-010398-5wot7tix 181 18 elements element NNS cord-010398-5wot7tix 181 19 formerly formerly RB cord-010398-5wot7tix 181 20 understood understand VBD cord-010398-5wot7tix 181 21 to to TO cord-010398-5wot7tix 181 22 be be VB cord-010398-5wot7tix 181 23 support support NN cord-010398-5wot7tix 181 24 structures structure NNS cord-010398-5wot7tix 181 25 has have VBZ cord-010398-5wot7tix 181 26 led lead VBN cord-010398-5wot7tix 181 27 to to IN cord-010398-5wot7tix 181 28 a a DT cord-010398-5wot7tix 181 29 critical critical JJ cord-010398-5wot7tix 181 30 reexamination reexamination NN cord-010398-5wot7tix 181 31 of of IN cord-010398-5wot7tix 181 32 whether whether IN cord-010398-5wot7tix 181 33 subtle subtle JJ cord-010398-5wot7tix 181 34 inflammatory inflammatory JJ cord-010398-5wot7tix 181 35 changes change NNS cord-010398-5wot7tix 181 36 in in IN cord-010398-5wot7tix 181 37 the the DT cord-010398-5wot7tix 181 38 central central JJ cord-010398-5wot7tix 181 39 nervous nervous JJ cord-010398-5wot7tix 181 40 system system NN cord-010398-5wot7tix 181 41 may may MD cord-010398-5wot7tix 181 42 be be VB cord-010398-5wot7tix 181 43 responsible responsible JJ cord-010398-5wot7tix 181 44 for for IN cord-010398-5wot7tix 181 45 some some DT cord-010398-5wot7tix 181 46 of of IN cord-010398-5wot7tix 181 47 the the DT cord-010398-5wot7tix 181 48 symptoms symptom NNS cord-010398-5wot7tix 181 49 observed observe VBN cord-010398-5wot7tix 181 50 in in IN cord-010398-5wot7tix 181 51 conditions condition NNS cord-010398-5wot7tix 181 52 such such JJ cord-010398-5wot7tix 181 53 as as IN cord-010398-5wot7tix 181 54 FM FM NNP cord-010398-5wot7tix 181 55 . . . cord-010398-5wot7tix 182 1 Immunological immunological JJ cord-010398-5wot7tix 182 2 cascades cascade NNS cord-010398-5wot7tix 182 3 have have VBP cord-010398-5wot7tix 182 4 a a DT cord-010398-5wot7tix 182 5 role role NN cord-010398-5wot7tix 182 6 in in IN cord-010398-5wot7tix 182 7 the the DT cord-010398-5wot7tix 182 8 maintenance maintenance NN cord-010398-5wot7tix 182 9 of of IN cord-010398-5wot7tix 182 10 central central JJ cord-010398-5wot7tix 182 11 sensitivity sensitivity NN cord-010398-5wot7tix 182 12 and and CC cord-010398-5wot7tix 182 13 chronic chronic JJ cord-010398-5wot7tix 182 14 pain pain NN cord-010398-5wot7tix 182 15 , , , cord-010398-5wot7tix 182 16 which which WDT cord-010398-5wot7tix 182 17 is be VBZ cord-010398-5wot7tix 182 18 enhanced enhance VBN cord-010398-5wot7tix 182 19 through through IN cord-010398-5wot7tix 182 20 release release NN cord-010398-5wot7tix 182 21 of of IN cord-010398-5wot7tix 182 22 proinflammatory proinflammatory JJ cord-010398-5wot7tix 182 23 cytokines cytokine NNS cord-010398-5wot7tix 182 24 by by IN cord-010398-5wot7tix 182 25 central central JJ cord-010398-5wot7tix 182 26 nervous nervous JJ cord-010398-5wot7tix 182 27 system system NN cord-010398-5wot7tix 182 28 glial glial NN cord-010398-5wot7tix 182 29 cells cell NNS cord-010398-5wot7tix 182 30 ; ; : cord-010398-5wot7tix 182 31 thus thus RB cord-010398-5wot7tix 182 32 , , , cord-010398-5wot7tix 182 33 the the DT cord-010398-5wot7tix 182 34 traditional traditional JJ cord-010398-5wot7tix 182 35 paradigm paradigm NN cord-010398-5wot7tix 182 36 of of IN cord-010398-5wot7tix 182 37 inflammatory inflammatory JJ cord-010398-5wot7tix 182 38 versus versus IN cord-010398-5wot7tix 182 39 noninflammatory noninflammatory JJ cord-010398-5wot7tix 182 40 pain pain NN cord-010398-5wot7tix 182 41 may may MD cord-010398-5wot7tix 182 42 gradually gradually RB cord-010398-5wot7tix 182 43 be be VB cord-010398-5wot7tix 182 44 understood understand VBN cord-010398-5wot7tix 182 45 as as IN cord-010398-5wot7tix 182 46 less less RBR cord-010398-5wot7tix 182 47 dichotomous dichotomous JJ cord-010398-5wot7tix 182 48 . . . cord-010398-5wot7tix 183 1 As as IN cord-010398-5wot7tix 183 2 briefly briefly NN cord-010398-5wot7tix 183 3 discussed discuss VBN cord-010398-5wot7tix 183 4 , , , cord-010398-5wot7tix 183 5 a a DT cord-010398-5wot7tix 183 6 major major JJ cord-010398-5wot7tix 183 7 pathophysiological pathophysiological JJ cord-010398-5wot7tix 183 8 finding finding NN cord-010398-5wot7tix 183 9 in in IN cord-010398-5wot7tix 183 10 all all DT cord-010398-5wot7tix 183 11 related related JJ cord-010398-5wot7tix 183 12 syndromes syndrome NNS cord-010398-5wot7tix 183 13 that that WDT cord-010398-5wot7tix 183 14 share share VBP cord-010398-5wot7tix 183 15 overlapping overlap VBG cord-010398-5wot7tix 183 16 clinical clinical JJ cord-010398-5wot7tix 183 17 and and CC cord-010398-5wot7tix 183 18 pathogenic pathogenic JJ cord-010398-5wot7tix 183 19 features feature NNS cord-010398-5wot7tix 183 20 with with IN cord-010398-5wot7tix 183 21 CFS CFS NNP cord-010398-5wot7tix 183 22 , , , cord-010398-5wot7tix 183 23 such such JJ cord-010398-5wot7tix 183 24 as as IN cord-010398-5wot7tix 183 25 FM FM NNP cord-010398-5wot7tix 183 26 , , , cord-010398-5wot7tix 183 27 IBS IBS NNP cord-010398-5wot7tix 183 28 , , , cord-010398-5wot7tix 183 29 chronic chronic JJ cord-010398-5wot7tix 183 30 headache headache NN cord-010398-5wot7tix 183 31 , , , cord-010398-5wot7tix 183 32 and and CC cord-010398-5wot7tix 183 33 interstitial interstitial JJ cord-010398-5wot7tix 183 34 cystitis cystitis NN cord-010398-5wot7tix 183 35 , , , cord-010398-5wot7tix 183 36 is be VBZ cord-010398-5wot7tix 183 37 that that IN cord-010398-5wot7tix 183 38 these these DT cord-010398-5wot7tix 183 39 conditions condition NNS cord-010398-5wot7tix 183 40 are be VBP cord-010398-5wot7tix 183 41 characterized characterize VBN cord-010398-5wot7tix 183 42 by by IN cord-010398-5wot7tix 183 43 hyperalgesia hyperalgesia NN cord-010398-5wot7tix 183 44 and and CC cord-010398-5wot7tix 183 45 allodynia allodynia NN cord-010398-5wot7tix 183 46 , , , cord-010398-5wot7tix 183 47 both both DT cord-010398-5wot7tix 183 48 on on IN cord-010398-5wot7tix 183 49 experimental experimental JJ cord-010398-5wot7tix 183 50 pain pain NN cord-010398-5wot7tix 183 51 testing testing NN cord-010398-5wot7tix 183 52 as as RB cord-010398-5wot7tix 183 53 well well RB cord-010398-5wot7tix 183 54 as as IN cord-010398-5wot7tix 183 55 functional functional JJ cord-010398-5wot7tix 183 56 neuroimaging neuroimaging NN cord-010398-5wot7tix 183 57 . . . cord-010398-5wot7tix 184 1 The the DT cord-010398-5wot7tix 184 2 authors author NNS cord-010398-5wot7tix 184 3 of of IN cord-010398-5wot7tix 184 4 early early JJ cord-010398-5wot7tix 184 5 studies study NNS cord-010398-5wot7tix 184 6 typically typically RB cord-010398-5wot7tix 184 7 used use VBD cord-010398-5wot7tix 184 8 dolorimetry dolorimetry NNP cord-010398-5wot7tix 184 9 to to TO cord-010398-5wot7tix 184 10 assess assess VB cord-010398-5wot7tix 184 11 pressure pressure NN cord-010398-5wot7tix 184 12 pain pain NN cord-010398-5wot7tix 184 13 threshold threshold NN cord-010398-5wot7tix 184 14 and and CC cord-010398-5wot7tix 184 15 concluded conclude VBD cord-010398-5wot7tix 184 16 that that IN cord-010398-5wot7tix 184 17 tenderness tenderness NN cord-010398-5wot7tix 184 18 was be VBD cord-010398-5wot7tix 184 19 in in IN cord-010398-5wot7tix 184 20 large large JJ cord-010398-5wot7tix 184 21 part part NN cord-010398-5wot7tix 184 22 related relate VBN cord-010398-5wot7tix 184 23 to to IN cord-010398-5wot7tix 184 24 psychological psychological JJ cord-010398-5wot7tix 184 25 factors factor NNS cord-010398-5wot7tix 184 26 because because IN cord-010398-5wot7tix 184 27 these these DT cord-010398-5wot7tix 184 28 measures measure NNS cord-010398-5wot7tix 184 29 of of IN cord-010398-5wot7tix 184 30 pain pain NN cord-010398-5wot7tix 184 31 threshold threshold NN cord-010398-5wot7tix 184 32 were be VBD cord-010398-5wot7tix 184 33 correlated correlate VBN cord-010398-5wot7tix 184 34 with with IN cord-010398-5wot7tix 184 35 levels level NNS cord-010398-5wot7tix 184 36 of of IN cord-010398-5wot7tix 184 37 distress distress NN cord-010398-5wot7tix 184 38 [ [ -LRB- cord-010398-5wot7tix 184 39 83 83 CD cord-010398-5wot7tix 184 40 ] ] -RRB- cord-010398-5wot7tix 184 41 [ [ -LRB- cord-010398-5wot7tix 184 42 84 84 CD cord-010398-5wot7tix 184 43 ] ] -RRB- cord-010398-5wot7tix 184 44 [ [ -LRB- cord-010398-5wot7tix 184 45 85 85 CD cord-010398-5wot7tix 184 46 ] ] -RRB- cord-010398-5wot7tix 184 47 . . . cord-010398-5wot7tix 185 1 To to TO cord-010398-5wot7tix 185 2 minimize minimize VB cord-010398-5wot7tix 185 3 the the DT cord-010398-5wot7tix 185 4 biases bias NNS cord-010398-5wot7tix 185 5 associated associate VBN cord-010398-5wot7tix 185 6 with with IN cord-010398-5wot7tix 185 7 " " `` cord-010398-5wot7tix 185 8 ascending ascend VBG cord-010398-5wot7tix 185 9 " " '' cord-010398-5wot7tix 185 10 ( ( -LRB- cord-010398-5wot7tix 185 11 ie ie FW cord-010398-5wot7tix 185 12 , , , cord-010398-5wot7tix 185 13 the the DT cord-010398-5wot7tix 185 14 individual individual NN cord-010398-5wot7tix 185 15 knows know VBZ cord-010398-5wot7tix 185 16 that that IN cord-010398-5wot7tix 185 17 the the DT cord-010398-5wot7tix 185 18 pressure pressure NN cord-010398-5wot7tix 185 19 will will MD cord-010398-5wot7tix 185 20 be be VB cord-010398-5wot7tix 185 21 predictably predictably RB cord-010398-5wot7tix 185 22 increased increase VBN cord-010398-5wot7tix 185 23 ) ) -RRB- cord-010398-5wot7tix 185 24 measures measure NNS cord-010398-5wot7tix 185 25 of of IN cord-010398-5wot7tix 185 26 pressure pressure NN cord-010398-5wot7tix 185 27 pain pain NN cord-010398-5wot7tix 185 28 threshold threshold NN cord-010398-5wot7tix 185 29 , , , cord-010398-5wot7tix 185 30 Petzke Petzke NNP cord-010398-5wot7tix 185 31 and and CC cord-010398-5wot7tix 185 32 colleagues colleague NNS cord-010398-5wot7tix 185 33 [ [ -LRB- cord-010398-5wot7tix 185 34 86 86 CD cord-010398-5wot7tix 185 35 ] ] -RRB- cord-010398-5wot7tix 185 36 [ [ -LRB- cord-010398-5wot7tix 185 37 87 87 CD cord-010398-5wot7tix 185 38 ] ] -RRB- cord-010398-5wot7tix 185 39 [ [ -LRB- cord-010398-5wot7tix 185 40 88 88 CD cord-010398-5wot7tix 185 41 ] ] -RRB- cord-010398-5wot7tix 186 1 [ [ -LRB- cord-010398-5wot7tix 186 2 89 89 CD cord-010398-5wot7tix 186 3 ] ] -RRB- cord-010398-5wot7tix 186 4 performed perform VBD cord-010398-5wot7tix 186 5 a a DT cord-010398-5wot7tix 186 6 series series NN cord-010398-5wot7tix 186 7 of of IN cord-010398-5wot7tix 186 8 studies study NNS cord-010398-5wot7tix 186 9 using use VBG cord-010398-5wot7tix 186 10 more more RBR cord-010398-5wot7tix 186 11 sophisticated sophisticated JJ cord-010398-5wot7tix 186 12 paradigms paradigm NNS cord-010398-5wot7tix 186 13 , , , cord-010398-5wot7tix 186 14 including include VBG cord-010398-5wot7tix 186 15 random random JJ cord-010398-5wot7tix 186 16 delivery delivery NN cord-010398-5wot7tix 186 17 of of IN cord-010398-5wot7tix 186 18 pressures pressure NNS cord-010398-5wot7tix 186 19 . . . cord-010398-5wot7tix 187 1 These these DT cord-010398-5wot7tix 187 2 studies study NNS cord-010398-5wot7tix 187 3 showed show VBD cord-010398-5wot7tix 187 4 that that IN cord-010398-5wot7tix 187 5 : : : cord-010398-5wot7tix 187 6 ( ( -LRB- cord-010398-5wot7tix 187 7 1 1 LS cord-010398-5wot7tix 187 8 ) ) -RRB- cord-010398-5wot7tix 187 9 the the DT cord-010398-5wot7tix 187 10 random random JJ cord-010398-5wot7tix 187 11 measures measure NNS cord-010398-5wot7tix 187 12 of of IN cord-010398-5wot7tix 187 13 pressure pressure NN cord-010398-5wot7tix 187 14 pain pain NN cord-010398-5wot7tix 187 15 threshold threshold NN cord-010398-5wot7tix 187 16 were be VBD cord-010398-5wot7tix 187 17 not not RB cord-010398-5wot7tix 187 18 influenced influence VBN cord-010398-5wot7tix 187 19 by by IN cord-010398-5wot7tix 187 20 levels level NNS cord-010398-5wot7tix 187 21 of of IN cord-010398-5wot7tix 187 22 distress distress NN cord-010398-5wot7tix 187 23 of of IN cord-010398-5wot7tix 187 24 the the DT cord-010398-5wot7tix 187 25 individual individual NN cord-010398-5wot7tix 187 26 , , , cord-010398-5wot7tix 187 27 whereas whereas IN cord-010398-5wot7tix 187 28 tender tender NN cord-010398-5wot7tix 187 29 point point NN cord-010398-5wot7tix 187 30 count count NN cord-010398-5wot7tix 187 31 and and CC cord-010398-5wot7tix 187 32 dolorimetry dolorimetry NN cord-010398-5wot7tix 187 33 examinations examination NNS cord-010398-5wot7tix 187 34 were be VBD cord-010398-5wot7tix 187 35 ; ; : cord-010398-5wot7tix 187 36 ( ( -LRB- cord-010398-5wot7tix 187 37 2 2 LS cord-010398-5wot7tix 187 38 ) ) -RRB- cord-010398-5wot7tix 187 39 patients patient NNS cord-010398-5wot7tix 187 40 with with IN cord-010398-5wot7tix 187 41 FM FM NNP cord-010398-5wot7tix 187 42 were be VBD cord-010398-5wot7tix 187 43 much much RB cord-010398-5wot7tix 187 44 more more RBR cord-010398-5wot7tix 187 45 sensitive sensitive JJ cord-010398-5wot7tix 187 46 to to IN cord-010398-5wot7tix 187 47 pressure pressure NN cord-010398-5wot7tix 187 48 even even RB cord-010398-5wot7tix 187 49 when when WRB cord-010398-5wot7tix 187 50 these these DT cord-010398-5wot7tix 187 51 more more RBR cord-010398-5wot7tix 187 52 sophisticated sophisticated JJ cord-010398-5wot7tix 187 53 paradigms paradigm NNS cord-010398-5wot7tix 187 54 were be VBD cord-010398-5wot7tix 187 55 used use VBN cord-010398-5wot7tix 187 56 ; ; : cord-010398-5wot7tix 187 57 ( ( -LRB- cord-010398-5wot7tix 187 58 3 3 LS cord-010398-5wot7tix 187 59 ) ) -RRB- cord-010398-5wot7tix 187 60 patients patient NNS cord-010398-5wot7tix 187 61 with with IN cord-010398-5wot7tix 187 62 FM FM NNP cord-010398-5wot7tix 187 63 were be VBD cord-010398-5wot7tix 187 64 not not RB cord-010398-5wot7tix 187 65 any any DT cord-010398-5wot7tix 187 66 more more RBR cord-010398-5wot7tix 187 67 " " `` cord-010398-5wot7tix 187 68 expectant expectant JJ cord-010398-5wot7tix 187 69 " " '' cord-010398-5wot7tix 187 70 or or CC cord-010398-5wot7tix 187 71 " " `` cord-010398-5wot7tix 187 72 hypervigilant hypervigilant JJ cord-010398-5wot7tix 187 73 " " '' cord-010398-5wot7tix 187 74 than than IN cord-010398-5wot7tix 187 75 control control NN cord-010398-5wot7tix 187 76 patients patient NNS cord-010398-5wot7tix 187 77 ; ; : cord-010398-5wot7tix 187 78 and and CC cord-010398-5wot7tix 187 79 ( ( -LRB- cord-010398-5wot7tix 187 80 4 4 LS cord-010398-5wot7tix 187 81 ) ) -RRB- cord-010398-5wot7tix 187 82 pressure pressure NN cord-010398-5wot7tix 187 83 pain pain NN cord-010398-5wot7tix 187 84 thresholds threshold NNS cord-010398-5wot7tix 187 85 at at IN cord-010398-5wot7tix 187 86 any any DT cord-010398-5wot7tix 187 87 4 4 CD cord-010398-5wot7tix 187 88 points point NNS cord-010398-5wot7tix 187 89 in in IN cord-010398-5wot7tix 187 90 the the DT cord-010398-5wot7tix 187 91 body body NN cord-010398-5wot7tix 187 92 are be VBP cord-010398-5wot7tix 187 93 highly highly RB cord-010398-5wot7tix 187 94 correlated correlate VBN cord-010398-5wot7tix 187 95 with with IN cord-010398-5wot7tix 187 96 the the DT cord-010398-5wot7tix 187 97 average average JJ cord-010398-5wot7tix 187 98 tenderness tenderness NN cord-010398-5wot7tix 187 99 at at IN cord-010398-5wot7tix 187 100 all all RB cord-010398-5wot7tix 187 101 18 18 CD cord-010398-5wot7tix 187 102 tender tender NN cord-010398-5wot7tix 187 103 points point NNS cord-010398-5wot7tix 187 104 and and CC cord-010398-5wot7tix 187 105 4 4 CD cord-010398-5wot7tix 187 106 " " `` cord-010398-5wot7tix 187 107 control control NN cord-010398-5wot7tix 187 108 points point NNS cord-010398-5wot7tix 187 109 " " '' cord-010398-5wot7tix 187 110 ( ( -LRB- cord-010398-5wot7tix 187 111 the the DT cord-010398-5wot7tix 187 112 thumbnail thumbnail NN cord-010398-5wot7tix 187 113 and and CC cord-010398-5wot7tix 187 114 forehead forehead NN cord-010398-5wot7tix 187 115 ) ) -RRB- cord-010398-5wot7tix 187 116 . . . cord-010398-5wot7tix 188 1 In in IN cord-010398-5wot7tix 188 2 addition addition NN cord-010398-5wot7tix 188 3 to to IN cord-010398-5wot7tix 188 4 the the DT cord-010398-5wot7tix 188 5 heightened heightened JJ cord-010398-5wot7tix 188 6 sensitivity sensitivity NN cord-010398-5wot7tix 188 7 to to IN cord-010398-5wot7tix 188 8 pressure pressure NN cord-010398-5wot7tix 188 9 noted note VBN cord-010398-5wot7tix 188 10 in in IN cord-010398-5wot7tix 188 11 FM FM NNP cord-010398-5wot7tix 188 12 , , , cord-010398-5wot7tix 188 13 other other JJ cord-010398-5wot7tix 188 14 types type NNS cord-010398-5wot7tix 188 15 of of IN cord-010398-5wot7tix 188 16 stimuli stimulus NNS cord-010398-5wot7tix 188 17 applied apply VBN cord-010398-5wot7tix 188 18 to to IN cord-010398-5wot7tix 188 19 the the DT cord-010398-5wot7tix 188 20 skin skin NN cord-010398-5wot7tix 188 21 are be VBP cord-010398-5wot7tix 188 22 also also RB cord-010398-5wot7tix 188 23 judged judge VBN cord-010398-5wot7tix 188 24 as as IN cord-010398-5wot7tix 188 25 more more RBR cord-010398-5wot7tix 188 26 painful painful JJ cord-010398-5wot7tix 188 27 or or CC cord-010398-5wot7tix 188 28 noxious noxious JJ cord-010398-5wot7tix 188 29 by by IN cord-010398-5wot7tix 188 30 these these DT cord-010398-5wot7tix 188 31 patients patient NNS cord-010398-5wot7tix 188 32 , , , cord-010398-5wot7tix 188 33 including include VBG cord-010398-5wot7tix 188 34 heat heat NN cord-010398-5wot7tix 188 35 [ [ -LRB- cord-010398-5wot7tix 188 36 88 88 CD cord-010398-5wot7tix 188 37 , , , cord-010398-5wot7tix 188 38 [ [ -LRB- cord-010398-5wot7tix 188 39 90 90 CD cord-010398-5wot7tix 188 40 ] ] -RRB- cord-010398-5wot7tix 188 41 [ [ -LRB- cord-010398-5wot7tix 188 42 91 91 CD cord-010398-5wot7tix 188 43 ] ] -RRB- cord-010398-5wot7tix 188 44 [ [ -LRB- cord-010398-5wot7tix 188 45 92 92 CD cord-010398-5wot7tix 188 46 ] ] -RRB- cord-010398-5wot7tix 188 47 , , , cord-010398-5wot7tix 188 48 cold cold JJ cord-010398-5wot7tix 188 49 [ [ -LRB- cord-010398-5wot7tix 188 50 91 91 CD cord-010398-5wot7tix 188 51 , , , cord-010398-5wot7tix 188 52 93 93 CD cord-010398-5wot7tix 188 53 ] ] -RRB- cord-010398-5wot7tix 188 54 , , , cord-010398-5wot7tix 188 55 and and CC cord-010398-5wot7tix 188 56 electrical electrical JJ cord-010398-5wot7tix 188 57 stimuli stimulus NNS cord-010398-5wot7tix 188 58 [ [ -LRB- cord-010398-5wot7tix 188 59 94 94 CD cord-010398-5wot7tix 188 60 ] ] -RRB- cord-010398-5wot7tix 188 61 . . . cord-010398-5wot7tix 189 1 These these DT cord-010398-5wot7tix 189 2 same same JJ cord-010398-5wot7tix 189 3 findings finding NNS cord-010398-5wot7tix 189 4 of of IN cord-010398-5wot7tix 189 5 hyperalgesia hyperalgesia NN cord-010398-5wot7tix 189 6 and and CC cord-010398-5wot7tix 189 7 allodynia allodynia NN cord-010398-5wot7tix 189 8 have have VBP cord-010398-5wot7tix 189 9 been be VBN cord-010398-5wot7tix 189 10 noted note VBN cord-010398-5wot7tix 189 11 in in IN cord-010398-5wot7tix 189 12 most most JJS cord-010398-5wot7tix 189 13 of of IN cord-010398-5wot7tix 189 14 the the DT cord-010398-5wot7tix 189 15 other other JJ cord-010398-5wot7tix 189 16 conditions condition NNS cord-010398-5wot7tix 189 17 acknowledged acknowledge VBN cord-010398-5wot7tix 189 18 to to TO cord-010398-5wot7tix 189 19 be be VB cord-010398-5wot7tix 189 20 part part NN cord-010398-5wot7tix 189 21 of of IN cord-010398-5wot7tix 189 22 this this DT cord-010398-5wot7tix 189 23 continuum continuum NN cord-010398-5wot7tix 189 24 , , , cord-010398-5wot7tix 189 25 including include VBG cord-010398-5wot7tix 189 26 CFS CFS NNP cord-010398-5wot7tix 189 27 , , , cord-010398-5wot7tix 189 28 IBS IBS NNP cord-010398-5wot7tix 189 29 , , , cord-010398-5wot7tix 189 30 TMJD TMJD NNP cord-010398-5wot7tix 189 31 , , , cord-010398-5wot7tix 189 32 tension tension NN cord-010398-5wot7tix 189 33 type type NN cord-010398-5wot7tix 189 34 headache headache NN cord-010398-5wot7tix 189 35 , , , cord-010398-5wot7tix 189 36 idiopathic idiopathic JJ cord-010398-5wot7tix 189 37 low low JJ cord-010398-5wot7tix 189 38 back back JJ cord-010398-5wot7tix 189 39 pain pain NN cord-010398-5wot7tix 189 40 , , , cord-010398-5wot7tix 189 41 vulvodynia vulvodynia NN cord-010398-5wot7tix 189 42 , , , cord-010398-5wot7tix 189 43 and and CC cord-010398-5wot7tix 189 44 interstitial interstitial JJ cord-010398-5wot7tix 189 45 cystitis cystitis NN cord-010398-5wot7tix 189 46 [ [ -LRB- cord-010398-5wot7tix 189 47 95 95 CD cord-010398-5wot7tix 189 48 ] ] -RRB- cord-010398-5wot7tix 190 1 [ [ -LRB- cord-010398-5wot7tix 190 2 96 96 CD cord-010398-5wot7tix 190 3 ] ] -RRB- cord-010398-5wot7tix 190 4 [ [ -LRB- cord-010398-5wot7tix 190 5 97 97 CD cord-010398-5wot7tix 190 6 ] ] -RRB- cord-010398-5wot7tix 190 7 [ [ -LRB- cord-010398-5wot7tix 190 8 98 98 CD cord-010398-5wot7tix 190 9 ] ] -RRB- cord-010398-5wot7tix 190 10 [ [ -LRB- cord-010398-5wot7tix 190 11 99 99 CD cord-010398-5wot7tix 190 12 ] ] -RRB- cord-010398-5wot7tix 190 13 . . . cord-010398-5wot7tix 191 1 Brain brain NN cord-010398-5wot7tix 191 2 imaging imaging NN cord-010398-5wot7tix 191 3 studies study NNS cord-010398-5wot7tix 191 4 also also RB cord-010398-5wot7tix 191 5 demonstrate demonstrate VBP cord-010398-5wot7tix 191 6 the the DT cord-010398-5wot7tix 191 7 existence existence NN cord-010398-5wot7tix 191 8 of of IN cord-010398-5wot7tix 191 9 central central JJ cord-010398-5wot7tix 191 10 pain pain NN cord-010398-5wot7tix 191 11 augmentation augmentation NN cord-010398-5wot7tix 191 12 in in IN cord-010398-5wot7tix 191 13 FM FM NNP cord-010398-5wot7tix 191 14 , , , cord-010398-5wot7tix 191 15 IBS IBS NNP cord-010398-5wot7tix 191 16 , , , cord-010398-5wot7tix 191 17 low low JJ cord-010398-5wot7tix 191 18 back back JJ cord-010398-5wot7tix 191 19 pain pain NN cord-010398-5wot7tix 191 20 , , , cord-010398-5wot7tix 191 21 and and CC cord-010398-5wot7tix 191 22 several several JJ cord-010398-5wot7tix 191 23 other other JJ cord-010398-5wot7tix 191 24 conditions condition NNS cord-010398-5wot7tix 191 25 [ [ -LRB- cord-010398-5wot7tix 191 26 100 100 CD cord-010398-5wot7tix 191 27 ] ] -RRB- cord-010398-5wot7tix 191 28 [ [ -LRB- cord-010398-5wot7tix 191 29 101 101 CD cord-010398-5wot7tix 191 30 ] ] -RRB- cord-010398-5wot7tix 191 31 [ [ -LRB- cord-010398-5wot7tix 191 32 102 102 CD cord-010398-5wot7tix 191 33 ] ] -RRB- cord-010398-5wot7tix 191 34 . . . cord-010398-5wot7tix 192 1 Finally finally RB cord-010398-5wot7tix 192 2 , , , cord-010398-5wot7tix 192 3 recent recent JJ cord-010398-5wot7tix 192 4 studies study NNS cord-010398-5wot7tix 192 5 have have VBP cord-010398-5wot7tix 192 6 suggested suggest VBN cord-010398-5wot7tix 192 7 that that IN cord-010398-5wot7tix 192 8 FM FM NNP cord-010398-5wot7tix 192 9 and and CC cord-010398-5wot7tix 192 10 other other JJ cord-010398-5wot7tix 192 11 chronic chronic JJ cord-010398-5wot7tix 192 12 pain pain NN cord-010398-5wot7tix 192 13 states state NNS cord-010398-5wot7tix 192 14 are be VBP cord-010398-5wot7tix 192 15 not not RB cord-010398-5wot7tix 192 16 just just RB cord-010398-5wot7tix 192 17 characterized characterize VBN cord-010398-5wot7tix 192 18 by by IN cord-010398-5wot7tix 192 19 hyperresponsiveness hyperresponsiveness NN cord-010398-5wot7tix 192 20 to to IN cord-010398-5wot7tix 192 21 painful painful JJ cord-010398-5wot7tix 192 22 somatic somatic JJ cord-010398-5wot7tix 192 23 or or CC cord-010398-5wot7tix 192 24 visceral visceral JJ cord-010398-5wot7tix 192 25 stimuli stimulus NNS cord-010398-5wot7tix 192 26 but but CC cord-010398-5wot7tix 192 27 that that IN cord-010398-5wot7tix 192 28 they -PRON- PRP cord-010398-5wot7tix 192 29 also also RB cord-010398-5wot7tix 192 30 exhibit exhibit VBP cord-010398-5wot7tix 192 31 a a DT cord-010398-5wot7tix 192 32 " " `` cord-010398-5wot7tix 192 33 left left JJ cord-010398-5wot7tix 192 34 - - HYPH cord-010398-5wot7tix 192 35 shift shift NN cord-010398-5wot7tix 192 36 " " '' cord-010398-5wot7tix 192 37 in in IN cord-010398-5wot7tix 192 38 noxiousness noxiousness NN cord-010398-5wot7tix 192 39 or or CC cord-010398-5wot7tix 192 40 unpleasantness unpleasantness NN cord-010398-5wot7tix 192 41 of of IN cord-010398-5wot7tix 192 42 other other JJ cord-010398-5wot7tix 192 43 sensory sensory JJ cord-010398-5wot7tix 192 44 experiences experience NNS cord-010398-5wot7tix 192 45 , , , cord-010398-5wot7tix 192 46 such such JJ cord-010398-5wot7tix 192 47 as as IN cord-010398-5wot7tix 192 48 the the DT cord-010398-5wot7tix 192 49 brightness brightness NN cord-010398-5wot7tix 192 50 of of IN cord-010398-5wot7tix 192 51 light light NN cord-010398-5wot7tix 192 52 or or CC cord-010398-5wot7tix 192 53 loudness loudness NN cord-010398-5wot7tix 192 54 of of IN cord-010398-5wot7tix 192 55 auditory auditory JJ cord-010398-5wot7tix 192 56 stimuli stimulus NNS cord-010398-5wot7tix 192 57 [ [ -LRB- cord-010398-5wot7tix 192 58 103 103 CD cord-010398-5wot7tix 192 59 , , , cord-010398-5wot7tix 192 60 104 104 CD cord-010398-5wot7tix 192 61 ] ] -RRB- cord-010398-5wot7tix 192 62 . . . cord-010398-5wot7tix 193 1 Geisser geisser NN cord-010398-5wot7tix 193 2 and and CC cord-010398-5wot7tix 193 3 colleagues colleague NNS cord-010398-5wot7tix 193 4 [ [ -LRB- cord-010398-5wot7tix 193 5 105 105 CD cord-010398-5wot7tix 193 6 , , , cord-010398-5wot7tix 193 7 106 106 CD cord-010398-5wot7tix 193 8 ] ] -RRB- cord-010398-5wot7tix 193 9 used use VBD cord-010398-5wot7tix 193 10 an an DT cord-010398-5wot7tix 193 11 identical identical JJ cord-010398-5wot7tix 193 12 random random JJ cord-010398-5wot7tix 193 13 staircase staircase NN cord-010398-5wot7tix 193 14 paradigm paradigm NN cord-010398-5wot7tix 193 15 to to TO cord-010398-5wot7tix 193 16 test test VB cord-010398-5wot7tix 193 17 FM FM NNP cord-010398-5wot7tix 193 18 and and CC cord-010398-5wot7tix 193 19 CFS CFS NNP cord-010398-5wot7tix 193 20 patients patient NNS cord-010398-5wot7tix 193 21 ' ' POS cord-010398-5wot7tix 193 22 threshold threshold NN cord-010398-5wot7tix 193 23 to to IN cord-010398-5wot7tix 193 24 the the DT cord-010398-5wot7tix 193 25 loudness loudness NN cord-010398-5wot7tix 193 26 of of IN cord-010398-5wot7tix 193 27 auditory auditory JJ cord-010398-5wot7tix 193 28 tones tone NNS cord-010398-5wot7tix 193 29 and and CC cord-010398-5wot7tix 193 30 to to TO cord-010398-5wot7tix 193 31 pressure pressure VB cord-010398-5wot7tix 193 32 . . . cord-010398-5wot7tix 194 1 They -PRON- PRP cord-010398-5wot7tix 194 2 found find VBD cord-010398-5wot7tix 194 3 that that IN cord-010398-5wot7tix 194 4 a a DT cord-010398-5wot7tix 194 5 measure measure NN cord-010398-5wot7tix 194 6 of of IN cord-010398-5wot7tix 194 7 sensory sensory JJ cord-010398-5wot7tix 194 8 sensitivity sensitivity NN cord-010398-5wot7tix 194 9 that that WDT cord-010398-5wot7tix 194 10 combined combine VBN cord-010398-5wot7tix 194 11 stimulus stimulus NN cord-010398-5wot7tix 194 12 : : : cord-010398-5wot7tix 194 13 response response NN cord-010398-5wot7tix 194 14 results result NNS cord-010398-5wot7tix 194 15 for for IN cord-010398-5wot7tix 194 16 both both DT cord-010398-5wot7tix 194 17 pressure pressure NN cord-010398-5wot7tix 194 18 pain pain NN cord-010398-5wot7tix 194 19 and and CC cord-010398-5wot7tix 194 20 auditory auditory JJ cord-010398-5wot7tix 194 21 unpleasantness unpleasantness NN cord-010398-5wot7tix 194 22 was be VBD cord-010398-5wot7tix 194 23 increased increase VBN cord-010398-5wot7tix 194 24 in in IN cord-010398-5wot7tix 194 25 both both DT cord-010398-5wot7tix 194 26 CFS CFS NNP cord-010398-5wot7tix 194 27 and and CC cord-010398-5wot7tix 194 28 FM FM NNP cord-010398-5wot7tix 194 29 patients patient NNS cord-010398-5wot7tix 194 30 compared compare VBN cord-010398-5wot7tix 194 31 with with IN cord-010398-5wot7tix 194 32 controls control NNS cord-010398-5wot7tix 194 33 , , , cord-010398-5wot7tix 194 34 was be VBD cord-010398-5wot7tix 194 35 independent independent JJ cord-010398-5wot7tix 194 36 of of IN cord-010398-5wot7tix 194 37 psychiatric psychiatric JJ cord-010398-5wot7tix 194 38 status status NN cord-010398-5wot7tix 194 39 , , , cord-010398-5wot7tix 194 40 and and CC cord-010398-5wot7tix 194 41 was be VBD cord-010398-5wot7tix 194 42 strongly strongly RB cord-010398-5wot7tix 194 43 correlated correlate VBN cord-010398-5wot7tix 194 44 with with IN cord-010398-5wot7tix 194 45 symptoms symptom NNS cord-010398-5wot7tix 194 46 as as RB cord-010398-5wot7tix 194 47 well well RB cord-010398-5wot7tix 194 48 as as IN cord-010398-5wot7tix 194 49 functional functional JJ cord-010398-5wot7tix 194 50 status status NN cord-010398-5wot7tix 194 51 in in IN cord-010398-5wot7tix 194 52 both both CC cord-010398-5wot7tix 194 53 CFS CFS NNP cord-010398-5wot7tix 194 54 and and CC cord-010398-5wot7tix 194 55 FM FM NNP cord-010398-5wot7tix 194 56 patients patient NNS cord-010398-5wot7tix 194 57 . . . cord-010398-5wot7tix 195 1 The the DT cord-010398-5wot7tix 195 2 notion notion NN cord-010398-5wot7tix 195 3 that that IN cord-010398-5wot7tix 195 4 FM FM NNP cord-010398-5wot7tix 195 5 and and CC cord-010398-5wot7tix 195 6 related relate VBN cord-010398-5wot7tix 195 7 syndromes syndrome NNS cord-010398-5wot7tix 195 8 might may MD cord-010398-5wot7tix 195 9 represent represent VB cord-010398-5wot7tix 195 10 syndromes syndrome NNS cord-010398-5wot7tix 195 11 in in IN cord-010398-5wot7tix 195 12 which which WDT cord-010398-5wot7tix 195 13 there there EX cord-010398-5wot7tix 195 14 is be VBZ cord-010398-5wot7tix 195 15 biological biological JJ cord-010398-5wot7tix 195 16 amplification amplification NN cord-010398-5wot7tix 195 17 of of IN cord-010398-5wot7tix 195 18 all all DT cord-010398-5wot7tix 195 19 sensory sensory JJ cord-010398-5wot7tix 195 20 stimuli stimulus NNS cord-010398-5wot7tix 195 21 has have VBZ cord-010398-5wot7tix 195 22 significant significant JJ cord-010398-5wot7tix 195 23 support support NN cord-010398-5wot7tix 195 24 from from IN cord-010398-5wot7tix 195 25 functional functional JJ cord-010398-5wot7tix 195 26 imaging imaging NN cord-010398-5wot7tix 195 27 studies study NNS cord-010398-5wot7tix 195 28 that that WDT cord-010398-5wot7tix 195 29 suggest suggest VBP cord-010398-5wot7tix 195 30 that that IN cord-010398-5wot7tix 195 31 the the DT cord-010398-5wot7tix 195 32 insula insula NN cord-010398-5wot7tix 195 33 is be VBZ cord-010398-5wot7tix 195 34 one one CD cord-010398-5wot7tix 195 35 of of IN cord-010398-5wot7tix 195 36 the the DT cord-010398-5wot7tix 195 37 most most RBS cord-010398-5wot7tix 195 38 consistently consistently RB cord-010398-5wot7tix 195 39 affected affect VBN cord-010398-5wot7tix 195 40 regions region NNS cord-010398-5wot7tix 195 41 . . . cord-010398-5wot7tix 196 1 This this DT cord-010398-5wot7tix 196 2 region region NN cord-010398-5wot7tix 196 3 has have VBZ cord-010398-5wot7tix 196 4 been be VBN cord-010398-5wot7tix 196 5 noted note VBN cord-010398-5wot7tix 196 6 to to TO cord-010398-5wot7tix 196 7 play play VB cord-010398-5wot7tix 196 8 a a DT cord-010398-5wot7tix 196 9 critical critical JJ cord-010398-5wot7tix 196 10 role role NN cord-010398-5wot7tix 196 11 in in IN cord-010398-5wot7tix 196 12 sensory sensory JJ cord-010398-5wot7tix 196 13 integration integration NN cord-010398-5wot7tix 196 14 , , , cord-010398-5wot7tix 196 15 with with IN cord-010398-5wot7tix 196 16 the the DT cord-010398-5wot7tix 196 17 posterior posterior NNP cord-010398-5wot7tix 196 18 insula insula NNP cord-010398-5wot7tix 196 19 serving serve VBG cord-010398-5wot7tix 196 20 a a DT cord-010398-5wot7tix 196 21 purer pure JJR cord-010398-5wot7tix 196 22 sensory sensory JJ cord-010398-5wot7tix 196 23 role role NN cord-010398-5wot7tix 196 24 and and CC cord-010398-5wot7tix 196 25 the the DT cord-010398-5wot7tix 196 26 anterior anterior NNP cord-010398-5wot7tix 196 27 insula insula NN cord-010398-5wot7tix 196 28 associated associate VBN cord-010398-5wot7tix 196 29 with with IN cord-010398-5wot7tix 196 30 the the DT cord-010398-5wot7tix 196 31 emotional emotional JJ cord-010398-5wot7tix 196 32 processing processing NN cord-010398-5wot7tix 196 33 of of IN cord-010398-5wot7tix 196 34 sensations sensation NNS cord-010398-5wot7tix 196 35 [ [ -LRB- cord-010398-5wot7tix 196 36 107 107 CD cord-010398-5wot7tix 196 37 ] ] -RRB- cord-010398-5wot7tix 196 38 [ [ -LRB- cord-010398-5wot7tix 196 39 108 108 CD cord-010398-5wot7tix 196 40 ] ] -RRB- cord-010398-5wot7tix 196 41 [ [ -LRB- cord-010398-5wot7tix 196 42 109 109 CD cord-010398-5wot7tix 196 43 ] ] -RRB- cord-010398-5wot7tix 196 44 . . . cord-010398-5wot7tix 197 1 Because because IN cord-010398-5wot7tix 197 2 self self NN cord-010398-5wot7tix 197 3 - - HYPH cord-010398-5wot7tix 197 4 report report NN cord-010398-5wot7tix 197 5 of of IN cord-010398-5wot7tix 197 6 both both CC cord-010398-5wot7tix 197 7 central central JJ cord-010398-5wot7tix 197 8 and and CC cord-010398-5wot7tix 197 9 peripheral peripheral JJ cord-010398-5wot7tix 197 10 fatigue fatigue NN cord-010398-5wot7tix 197 11 are be VBP cord-010398-5wot7tix 197 12 determined determine VBN cord-010398-5wot7tix 197 13 on on IN cord-010398-5wot7tix 197 14 the the DT cord-010398-5wot7tix 197 15 basis basis NN cord-010398-5wot7tix 197 16 of of IN cord-010398-5wot7tix 197 17 the the DT cord-010398-5wot7tix 197 18 patient patient NN cord-010398-5wot7tix 197 19 's 's POS cord-010398-5wot7tix 197 20 " " `` cord-010398-5wot7tix 197 21 perception perception NN cord-010398-5wot7tix 197 22 , , , cord-010398-5wot7tix 197 23 " " '' cord-010398-5wot7tix 197 24 it -PRON- PRP cord-010398-5wot7tix 197 25 is be VBZ cord-010398-5wot7tix 197 26 conceivable conceivable JJ cord-010398-5wot7tix 197 27 that that IN cord-010398-5wot7tix 197 28 sensory sensory JJ cord-010398-5wot7tix 197 29 amplification amplification NN cord-010398-5wot7tix 197 30 may may MD cord-010398-5wot7tix 197 31 be be VB cord-010398-5wot7tix 197 32 playing play VBG cord-010398-5wot7tix 197 33 a a DT cord-010398-5wot7tix 197 34 fundamental fundamental JJ cord-010398-5wot7tix 197 35 role role NN cord-010398-5wot7tix 197 36 in in IN cord-010398-5wot7tix 197 37 the the DT cord-010398-5wot7tix 197 38 pathogenesis pathogenesis NN cord-010398-5wot7tix 197 39 of of IN cord-010398-5wot7tix 197 40 CFS cfs NN cord-010398-5wot7tix 197 41 and and CC cord-010398-5wot7tix 197 42 may may MD cord-010398-5wot7tix 197 43 play play VB cord-010398-5wot7tix 197 44 a a DT cord-010398-5wot7tix 197 45 role role NN cord-010398-5wot7tix 197 46 in in IN cord-010398-5wot7tix 197 47 other other JJ cord-010398-5wot7tix 197 48 fatigue fatigue NN cord-010398-5wot7tix 197 49 states state NNS cord-010398-5wot7tix 197 50 . . . cord-010398-5wot7tix 198 1 No no DT cord-010398-5wot7tix 198 2 studies study NNS cord-010398-5wot7tix 198 3 have have VBP cord-010398-5wot7tix 198 4 directly directly RB cord-010398-5wot7tix 198 5 assessed assess VBN cord-010398-5wot7tix 198 6 this this DT cord-010398-5wot7tix 198 7 hypothesis hypothesis NN cord-010398-5wot7tix 198 8 in in IN cord-010398-5wot7tix 198 9 CFS CFS NNP cord-010398-5wot7tix 198 10 by by IN cord-010398-5wot7tix 198 11 demonstrating demonstrate VBG cord-010398-5wot7tix 198 12 a a DT cord-010398-5wot7tix 198 13 similar similar JJ cord-010398-5wot7tix 198 14 " " `` cord-010398-5wot7tix 198 15 left left JJ cord-010398-5wot7tix 198 16 - - HYPH cord-010398-5wot7tix 198 17 shift shift NN cord-010398-5wot7tix 198 18 " " '' cord-010398-5wot7tix 198 19 in in IN cord-010398-5wot7tix 198 20 many many JJ cord-010398-5wot7tix 198 21 stimulus stimulus NN cord-010398-5wot7tix 198 22 : : : cord-010398-5wot7tix 198 23 response response NN cord-010398-5wot7tix 198 24 functions function NNS cord-010398-5wot7tix 198 25 , , , cord-010398-5wot7tix 198 26 but but CC cord-010398-5wot7tix 198 27 nearly nearly RB cord-010398-5wot7tix 198 28 all all DT cord-010398-5wot7tix 198 29 studies study NNS cord-010398-5wot7tix 198 30 that that WDT cord-010398-5wot7tix 198 31 have have VBP cord-010398-5wot7tix 198 32 examined examine VBN cord-010398-5wot7tix 198 33 the the DT cord-010398-5wot7tix 198 34 fatigue fatigue NN cord-010398-5wot7tix 198 35 response response NN cord-010398-5wot7tix 198 36 to to IN cord-010398-5wot7tix 198 37 any any DT cord-010398-5wot7tix 198 38 single single JJ cord-010398-5wot7tix 198 39 stimuli stimulus NNS cord-010398-5wot7tix 198 40 ( ( -LRB- cord-010398-5wot7tix 198 41 eg eg RB cord-010398-5wot7tix 198 42 , , , cord-010398-5wot7tix 198 43 work work NN cord-010398-5wot7tix 198 44 performed perform VBN cord-010398-5wot7tix 198 45 on on IN cord-010398-5wot7tix 198 46 exercise exercise NN cord-010398-5wot7tix 198 47 or or CC cord-010398-5wot7tix 198 48 cognitive cognitive JJ cord-010398-5wot7tix 198 49 testing testing NN cord-010398-5wot7tix 198 50 ) ) -RRB- cord-010398-5wot7tix 198 51 have have VBP cord-010398-5wot7tix 198 52 noted note VBN cord-010398-5wot7tix 198 53 a a DT cord-010398-5wot7tix 198 54 similar similar JJ cord-010398-5wot7tix 198 55 left left JJ cord-010398-5wot7tix 198 56 - - HYPH cord-010398-5wot7tix 198 57 shift shift NN cord-010398-5wot7tix 198 58 to to IN cord-010398-5wot7tix 198 59 what what WP cord-010398-5wot7tix 198 60 has have VBZ cord-010398-5wot7tix 198 61 been be VBN cord-010398-5wot7tix 198 62 observed observe VBN cord-010398-5wot7tix 198 63 with with IN cord-010398-5wot7tix 198 64 other other JJ cord-010398-5wot7tix 198 65 sensory sensory JJ cord-010398-5wot7tix 198 66 experiences experience NNS cord-010398-5wot7tix 198 67 throughout throughout IN cord-010398-5wot7tix 198 68 this this DT cord-010398-5wot7tix 198 69 spectrum spectrum NN cord-010398-5wot7tix 198 70 of of IN cord-010398-5wot7tix 198 71 illness illness NN cord-010398-5wot7tix 198 72 [ [ -LRB- cord-010398-5wot7tix 198 73 25 25 CD cord-010398-5wot7tix 198 74 , , , cord-010398-5wot7tix 198 75 110 110 CD cord-010398-5wot7tix 198 76 ] ] -RRB- cord-010398-5wot7tix 198 77 . . . cord-010398-5wot7tix 199 1 Overall overall RB cord-010398-5wot7tix 199 2 , , , cord-010398-5wot7tix 199 3 the the DT cord-010398-5wot7tix 199 4 analogy analogy NN cord-010398-5wot7tix 199 5 of of IN cord-010398-5wot7tix 199 6 an an DT cord-010398-5wot7tix 199 7 increased increased JJ cord-010398-5wot7tix 199 8 " " '' cord-010398-5wot7tix 199 9 volume volume NN cord-010398-5wot7tix 199 10 control control NN cord-010398-5wot7tix 199 11 " " '' cord-010398-5wot7tix 199 12 or or CC cord-010398-5wot7tix 199 13 " " `` cord-010398-5wot7tix 199 14 gain gain NN cord-010398-5wot7tix 199 15 " " '' cord-010398-5wot7tix 199 16 setting set VBG cord-010398-5wot7tix 199 17 on on IN cord-010398-5wot7tix 199 18 pain pain NN cord-010398-5wot7tix 199 19 and and CC cord-010398-5wot7tix 199 20 sensory sensory JJ cord-010398-5wot7tix 199 21 processing processing NN cord-010398-5wot7tix 199 22 in in IN cord-010398-5wot7tix 199 23 conditions condition NNS cord-010398-5wot7tix 199 24 such such JJ cord-010398-5wot7tix 199 25 as as IN cord-010398-5wot7tix 199 26 FM FM NNP cord-010398-5wot7tix 199 27 and and CC cord-010398-5wot7tix 199 28 CFS CFS NNP cord-010398-5wot7tix 199 29 is be VBZ cord-010398-5wot7tix 199 30 supported support VBN cord-010398-5wot7tix 199 31 by by IN cord-010398-5wot7tix 199 32 studies study NNS cord-010398-5wot7tix 199 33 from from IN cord-010398-5wot7tix 199 34 a a DT cord-010398-5wot7tix 199 35 variety variety NN cord-010398-5wot7tix 199 36 of of IN cord-010398-5wot7tix 199 37 sources source NNS cord-010398-5wot7tix 199 38 and and CC cord-010398-5wot7tix 199 39 probably probably RB cord-010398-5wot7tix 199 40 is be VBZ cord-010398-5wot7tix 199 41 largely largely RB cord-010398-5wot7tix 199 42 responsible responsible JJ cord-010398-5wot7tix 199 43 for for IN cord-010398-5wot7tix 199 44 the the DT cord-010398-5wot7tix 199 45 acknowledged acknowledge VBN cord-010398-5wot7tix 199 46 overlap overlap NN cord-010398-5wot7tix 199 47 between between IN cord-010398-5wot7tix 199 48 these these DT cord-010398-5wot7tix 199 49 conditions condition NNS cord-010398-5wot7tix 199 50 and and CC cord-010398-5wot7tix 199 51 " " `` cord-010398-5wot7tix 199 52 multiple multiple JJ cord-010398-5wot7tix 199 53 chemical chemical NN cord-010398-5wot7tix 199 54 sensitivity sensitivity NN cord-010398-5wot7tix 199 55 , , , cord-010398-5wot7tix 199 56 " " '' cord-010398-5wot7tix 199 57 which which WDT cord-010398-5wot7tix 199 58 is be VBZ cord-010398-5wot7tix 199 59 a a DT cord-010398-5wot7tix 199 60 misnomer misnomer NN cord-010398-5wot7tix 199 61 because because IN cord-010398-5wot7tix 199 62 these these DT cord-010398-5wot7tix 199 63 patients patient NNS cord-010398-5wot7tix 199 64 also also RB cord-010398-5wot7tix 199 65 experience experience VBP cord-010398-5wot7tix 199 66 a a DT cord-010398-5wot7tix 199 67 left left JJ cord-010398-5wot7tix 199 68 - - HYPH cord-010398-5wot7tix 199 69 shift shift NN cord-010398-5wot7tix 199 70 in in IN cord-010398-5wot7tix 199 71 noxious noxious JJ cord-010398-5wot7tix 199 72 threshold threshold NN cord-010398-5wot7tix 199 73 to to IN cord-010398-5wot7tix 199 74 many many JJ cord-010398-5wot7tix 199 75 sensory sensory JJ cord-010398-5wot7tix 199 76 stimuli stimulus NNS cord-010398-5wot7tix 199 77 . . . cord-010398-5wot7tix 200 1 Similar similar JJ cord-010398-5wot7tix 200 2 to to IN cord-010398-5wot7tix 200 3 essential essential JJ cord-010398-5wot7tix 200 4 hypertension hypertension NN cord-010398-5wot7tix 200 5 in in IN cord-010398-5wot7tix 200 6 which which WDT cord-010398-5wot7tix 200 7 a a DT cord-010398-5wot7tix 200 8 variety variety NN cord-010398-5wot7tix 200 9 of of IN cord-010398-5wot7tix 200 10 root root NN cord-010398-5wot7tix 200 11 causes cause NNS cord-010398-5wot7tix 200 12 can can MD cord-010398-5wot7tix 200 13 lead lead VB cord-010398-5wot7tix 200 14 to to IN cord-010398-5wot7tix 200 15 elevated elevated JJ cord-010398-5wot7tix 200 16 systemic systemic JJ cord-010398-5wot7tix 200 17 blood blood NN cord-010398-5wot7tix 200 18 pressure pressure NN cord-010398-5wot7tix 200 19 , , , cord-010398-5wot7tix 200 20 these these DT cord-010398-5wot7tix 200 21 disorders disorder NNS cord-010398-5wot7tix 200 22 may may MD cord-010398-5wot7tix 200 23 in in IN cord-010398-5wot7tix 200 24 part part NN cord-010398-5wot7tix 200 25 represent represent VB cord-010398-5wot7tix 200 26 " " `` cord-010398-5wot7tix 200 27 essential essential JJ cord-010398-5wot7tix 200 28 hypertension hypertension NN cord-010398-5wot7tix 200 29 of of IN cord-010398-5wot7tix 200 30 pain pain NN cord-010398-5wot7tix 200 31 and and CC cord-010398-5wot7tix 200 32 sensory sensory JJ cord-010398-5wot7tix 200 33 processing processing NN cord-010398-5wot7tix 200 34 pathways pathway NNS cord-010398-5wot7tix 200 35 . . . cord-010398-5wot7tix 200 36 " " '' cord-010398-5wot7tix 201 1 In in IN cord-010398-5wot7tix 201 2 FM FM NNP cord-010398-5wot7tix 201 3 there there EX cord-010398-5wot7tix 201 4 has have VBZ cord-010398-5wot7tix 201 5 been be VBN cord-010398-5wot7tix 201 6 extensive extensive JJ cord-010398-5wot7tix 201 7 study study NN cord-010398-5wot7tix 201 8 of of IN cord-010398-5wot7tix 201 9 neurotransmitters neurotransmitter NNS cord-010398-5wot7tix 201 10 levels level NNS cord-010398-5wot7tix 201 11 that that WDT cord-010398-5wot7tix 201 12 tend tend VBP cord-010398-5wot7tix 201 13 to to TO cord-010398-5wot7tix 201 14 be be VB cord-010398-5wot7tix 201 15 pronociceptive pronociceptive JJ cord-010398-5wot7tix 201 16 ( ( -LRB- cord-010398-5wot7tix 201 17 ie ie FW cord-010398-5wot7tix 201 18 , , , cord-010398-5wot7tix 201 19 Figure Figure NNP cord-010398-5wot7tix 201 20 3 3 CD cord-010398-5wot7tix 201 21 , , , cord-010398-5wot7tix 201 22 left leave VBN cord-010398-5wot7tix 201 23 ) ) -RRB- cord-010398-5wot7tix 201 24 or or CC cord-010398-5wot7tix 201 25 inhibit inhibit VB cord-010398-5wot7tix 201 26 pain pain NN cord-010398-5wot7tix 201 27 transmission transmission NN cord-010398-5wot7tix 201 28 ( ( -LRB- cord-010398-5wot7tix 201 29 ie ie FW cord-010398-5wot7tix 201 30 , , , cord-010398-5wot7tix 201 31 Figure figure NN cord-010398-5wot7tix 201 32 3 3 CD cord-010398-5wot7tix 201 33 , , , cord-010398-5wot7tix 201 34 right right JJ cord-010398-5wot7tix 201 35 ) ) -RRB- cord-010398-5wot7tix 201 36 , , , cord-010398-5wot7tix 201 37 have have VBP cord-010398-5wot7tix 201 38 a a DT cord-010398-5wot7tix 201 39 tendency tendency NN cord-010398-5wot7tix 201 40 to to TO cord-010398-5wot7tix 201 41 increase increase VB cord-010398-5wot7tix 201 42 the the DT cord-010398-5wot7tix 201 43 volume volume NN cord-010398-5wot7tix 201 44 control control NN cord-010398-5wot7tix 201 45 . . . cord-010398-5wot7tix 202 1 Drugs drug NNS cord-010398-5wot7tix 202 2 that that WDT cord-010398-5wot7tix 202 3 block block VBP cord-010398-5wot7tix 202 4 neurotransmitters neurotransmitter NNS cord-010398-5wot7tix 202 5 on on IN cord-010398-5wot7tix 202 6 the the DT cord-010398-5wot7tix 202 7 left left NN cord-010398-5wot7tix 202 8 or or CC cord-010398-5wot7tix 202 9 augment augment VB cord-010398-5wot7tix 202 10 activity activity NN cord-010398-5wot7tix 202 11 of of IN cord-010398-5wot7tix 202 12 those those DT cord-010398-5wot7tix 202 13 on on IN cord-010398-5wot7tix 202 14 the the DT cord-010398-5wot7tix 202 15 right right NN cord-010398-5wot7tix 202 16 will will MD cord-010398-5wot7tix 202 17 typically typically RB cord-010398-5wot7tix 202 18 be be VB cord-010398-5wot7tix 202 19 found find VBN cord-010398-5wot7tix 202 20 to to TO cord-010398-5wot7tix 202 21 be be VB cord-010398-5wot7tix 202 22 effective effective JJ cord-010398-5wot7tix 202 23 treatments treatment NNS cord-010398-5wot7tix 202 24 , , , cord-010398-5wot7tix 202 25 at at IN cord-010398-5wot7tix 202 26 least least JJS cord-010398-5wot7tix 202 27 for for IN cord-010398-5wot7tix 202 28 a a DT cord-010398-5wot7tix 202 29 subset subset NN cord-010398-5wot7tix 202 30 of of IN cord-010398-5wot7tix 202 31 patients patient NNS cord-010398-5wot7tix 202 32 with with IN cord-010398-5wot7tix 202 33 this this DT cord-010398-5wot7tix 202 34 spectrum spectrum NN cord-010398-5wot7tix 202 35 of of IN cord-010398-5wot7tix 202 36 illness illness NN cord-010398-5wot7tix 202 37 . . . cord-010398-5wot7tix 203 1 The the DT cord-010398-5wot7tix 203 2 arrows arrow NNS cord-010398-5wot7tix 203 3 on on IN cord-010398-5wot7tix 203 4 Figure figure NN cord-010398-5wot7tix 203 5 3 3 CD cord-010398-5wot7tix 203 6 indicate indicate VBP cord-010398-5wot7tix 203 7 the the DT cord-010398-5wot7tix 203 8 direction direction NN cord-010398-5wot7tix 203 9 of of IN cord-010398-5wot7tix 203 10 the the DT cord-010398-5wot7tix 203 11 abnormalities abnormality NNS cord-010398-5wot7tix 203 12 in in IN cord-010398-5wot7tix 203 13 neurotransmitter neurotransmitter NN cord-010398-5wot7tix 203 14 levels level NNS cord-010398-5wot7tix 203 15 ( ( -LRB- cord-010398-5wot7tix 203 16 either either CC cord-010398-5wot7tix 203 17 in in IN cord-010398-5wot7tix 203 18 the the DT cord-010398-5wot7tix 203 19 cerebrospinal cerebrospinal NN cord-010398-5wot7tix 203 20 fluid fluid NN cord-010398-5wot7tix 203 21 [ [ -LRB- cord-010398-5wot7tix 203 22 CSF CSF NNP cord-010398-5wot7tix 203 23 ] ] -RRB- cord-010398-5wot7tix 203 24 or or CC cord-010398-5wot7tix 203 25 other other JJ cord-010398-5wot7tix 203 26 parts part NNS cord-010398-5wot7tix 203 27 of of IN cord-010398-5wot7tix 203 28 the the DT cord-010398-5wot7tix 203 29 brain brain NN cord-010398-5wot7tix 203 30 ) ) -RRB- cord-010398-5wot7tix 203 31 that that WDT cord-010398-5wot7tix 203 32 have have VBP cord-010398-5wot7tix 203 33 been be VBN cord-010398-5wot7tix 203 34 identified identify VBN cord-010398-5wot7tix 203 35 to to IN cord-010398-5wot7tix 203 36 date date NN cord-010398-5wot7tix 203 37 in in IN cord-010398-5wot7tix 203 38 FM FM NNP cord-010398-5wot7tix 203 39 . . . cord-010398-5wot7tix 204 1 As as IN cord-010398-5wot7tix 204 2 noted note VBN cord-010398-5wot7tix 204 3 , , , cord-010398-5wot7tix 204 4 in in IN cord-010398-5wot7tix 204 5 FM FM NNP cord-010398-5wot7tix 204 6 there there EX cord-010398-5wot7tix 204 7 is be VBZ cord-010398-5wot7tix 204 8 evidence evidence NN cord-010398-5wot7tix 204 9 for for IN cord-010398-5wot7tix 204 10 increases increase NNS cord-010398-5wot7tix 204 11 in in IN cord-010398-5wot7tix 204 12 the the DT cord-010398-5wot7tix 204 13 CSF CSF NNP cord-010398-5wot7tix 204 14 levels level NNS cord-010398-5wot7tix 204 15 of of IN cord-010398-5wot7tix 204 16 Substance Substance NNP cord-010398-5wot7tix 204 17 P p NN cord-010398-5wot7tix 204 18 , , , cord-010398-5wot7tix 204 19 glutamate glutamate NN cord-010398-5wot7tix 204 20 , , , cord-010398-5wot7tix 204 21 nerve nerve NN cord-010398-5wot7tix 204 22 growth growth NN cord-010398-5wot7tix 204 23 factor factor NN cord-010398-5wot7tix 204 24 , , , cord-010398-5wot7tix 204 25 and and CC cord-010398-5wot7tix 204 26 brain brain NN cord-010398-5wot7tix 204 27 - - HYPH cord-010398-5wot7tix 204 28 derived derive VBN cord-010398-5wot7tix 204 29 neurotrophic neurotrophic NN cord-010398-5wot7tix 204 30 factor factor NN cord-010398-5wot7tix 204 31 , , , cord-010398-5wot7tix 204 32 and and CC cord-010398-5wot7tix 204 33 low low JJ cord-010398-5wot7tix 204 34 levels level NNS cord-010398-5wot7tix 204 35 of of IN cord-010398-5wot7tix 204 36 the the DT cord-010398-5wot7tix 204 37 metabolites metabolite NNS cord-010398-5wot7tix 204 38 of of IN cord-010398-5wot7tix 204 39 serotonin serotonin NN cord-010398-5wot7tix 204 40 , , , cord-010398-5wot7tix 204 41 norepinephrine norepinephrine NN cord-010398-5wot7tix 204 42 , , , cord-010398-5wot7tix 204 43 and and CC cord-010398-5wot7tix 204 44 dopamine dopamine NN cord-010398-5wot7tix 204 45 . . . cord-010398-5wot7tix 205 1 Any any DT cord-010398-5wot7tix 205 2 of of IN cord-010398-5wot7tix 205 3 these these DT cord-010398-5wot7tix 205 4 could could MD cord-010398-5wot7tix 205 5 lead lead VB cord-010398-5wot7tix 205 6 to to IN cord-010398-5wot7tix 205 7 an an DT cord-010398-5wot7tix 205 8 " " `` cord-010398-5wot7tix 205 9 increase increase NN cord-010398-5wot7tix 205 10 in in IN cord-010398-5wot7tix 205 11 the the DT cord-010398-5wot7tix 205 12 volume volume NN cord-010398-5wot7tix 205 13 control control NN cord-010398-5wot7tix 205 14 " " '' cord-010398-5wot7tix 205 15 and and CC cord-010398-5wot7tix 205 16 augmented augment VBN cord-010398-5wot7tix 205 17 pain pain NN cord-010398-5wot7tix 205 18 and and CC cord-010398-5wot7tix 205 19 sensory sensory JJ cord-010398-5wot7tix 205 20 processing processing NN cord-010398-5wot7tix 205 21 [ [ -LRB- cord-010398-5wot7tix 205 22 111 111 CD cord-010398-5wot7tix 205 23 ] ] -RRB- cord-010398-5wot7tix 205 24 [ [ -LRB- cord-010398-5wot7tix 205 25 112 112 CD cord-010398-5wot7tix 205 26 ] ] -RRB- cord-010398-5wot7tix 205 27 [ [ -LRB- cord-010398-5wot7tix 205 28 113 113 CD cord-010398-5wot7tix 205 29 ] ] -RRB- cord-010398-5wot7tix 205 30 [ [ -LRB- cord-010398-5wot7tix 205 31 114 114 CD cord-010398-5wot7tix 205 32 ] ] -RRB- cord-010398-5wot7tix 205 33 . . . cord-010398-5wot7tix 206 1 The the DT cord-010398-5wot7tix 206 2 only only JJ cord-010398-5wot7tix 206 3 neurotransmitter neurotransmitter NN cord-010398-5wot7tix 206 4 system system NN cord-010398-5wot7tix 206 5 that that WDT cord-010398-5wot7tix 206 6 has have VBZ cord-010398-5wot7tix 206 7 been be VBN cord-010398-5wot7tix 206 8 studied study VBN cord-010398-5wot7tix 206 9 to to IN cord-010398-5wot7tix 206 10 date date NN cord-010398-5wot7tix 206 11 and and CC cord-010398-5wot7tix 206 12 not not RB cord-010398-5wot7tix 206 13 found find VBN cord-010398-5wot7tix 206 14 to to TO cord-010398-5wot7tix 206 15 be be VB cord-010398-5wot7tix 206 16 out out IN cord-010398-5wot7tix 206 17 of of IN cord-010398-5wot7tix 206 18 line line NN cord-010398-5wot7tix 206 19 in in IN cord-010398-5wot7tix 206 20 a a DT cord-010398-5wot7tix 206 21 direction direction NN cord-010398-5wot7tix 206 22 that that WDT cord-010398-5wot7tix 206 23 would would MD cord-010398-5wot7tix 206 24 cause cause VB cord-010398-5wot7tix 206 25 augmented augment VBN cord-010398-5wot7tix 206 26 pain pain NN cord-010398-5wot7tix 206 27 transmission transmission NN cord-010398-5wot7tix 206 28 is be VBZ cord-010398-5wot7tix 206 29 the the DT cord-010398-5wot7tix 206 30 endogenous endogenous JJ cord-010398-5wot7tix 206 31 opioid opioid NN cord-010398-5wot7tix 206 32 system system NN cord-010398-5wot7tix 206 33 . . . cord-010398-5wot7tix 207 1 Both both DT cord-010398-5wot7tix 207 2 CSF CSF NNP cord-010398-5wot7tix 207 3 levels level NNS cord-010398-5wot7tix 207 4 and and CC cord-010398-5wot7tix 207 5 brain brain NN cord-010398-5wot7tix 207 6 activity activity NN cord-010398-5wot7tix 207 7 by by IN cord-010398-5wot7tix 207 8 functional functional JJ cord-010398-5wot7tix 207 9 neuroimaging neuroimaging NN cord-010398-5wot7tix 207 10 appears appear VBZ cord-010398-5wot7tix 207 11 to to TO cord-010398-5wot7tix 207 12 be be VB cord-010398-5wot7tix 207 13 augmented augment VBN cord-010398-5wot7tix 207 14 , , , cord-010398-5wot7tix 207 15 not not RB cord-010398-5wot7tix 207 16 reduced reduce VBN cord-010398-5wot7tix 207 17 ( ( -LRB- cord-010398-5wot7tix 207 18 as as IN cord-010398-5wot7tix 207 19 would would MD cord-010398-5wot7tix 207 20 cause cause VB cord-010398-5wot7tix 207 21 augmented augment VBN cord-010398-5wot7tix 207 22 pain pain NN cord-010398-5wot7tix 207 23 processing processing NN cord-010398-5wot7tix 207 24 ) ) -RRB- cord-010398-5wot7tix 207 25 in in IN cord-010398-5wot7tix 207 26 FM FM NNP cord-010398-5wot7tix 207 27 , , , cord-010398-5wot7tix 207 28 which which WDT cord-010398-5wot7tix 207 29 may may MD cord-010398-5wot7tix 207 30 be be VB cord-010398-5wot7tix 207 31 why why WRB cord-010398-5wot7tix 207 32 opioidergic opioidergic JJ cord-010398-5wot7tix 207 33 drugs drug NNS cord-010398-5wot7tix 207 34 do do VBP cord-010398-5wot7tix 207 35 not not RB cord-010398-5wot7tix 207 36 work work VB cord-010398-5wot7tix 207 37 well well RB cord-010398-5wot7tix 207 38 to to TO cord-010398-5wot7tix 207 39 treat treat VB cord-010398-5wot7tix 207 40 FM FM NNP cord-010398-5wot7tix 207 41 and and CC cord-010398-5wot7tix 207 42 related related JJ cord-010398-5wot7tix 207 43 pain pain NN cord-010398-5wot7tix 207 44 syndromes syndrome NNS cord-010398-5wot7tix 207 45 [ [ -LRB- cord-010398-5wot7tix 207 46 115 115 CD cord-010398-5wot7tix 207 47 , , , cord-010398-5wot7tix 207 48 116 116 CD cord-010398-5wot7tix 207 49 ] ] -RRB- cord-010398-5wot7tix 207 50 . . . cord-010398-5wot7tix 208 1 It -PRON- PRP cord-010398-5wot7tix 208 2 is be VBZ cord-010398-5wot7tix 208 3 of of IN cord-010398-5wot7tix 208 4 note note NN cord-010398-5wot7tix 208 5 that that IN cord-010398-5wot7tix 208 6 nearly nearly RB cord-010398-5wot7tix 208 7 all all DT cord-010398-5wot7tix 208 8 of of IN cord-010398-5wot7tix 208 9 these these DT cord-010398-5wot7tix 208 10 neurotransmitters neurotransmitter NNS cord-010398-5wot7tix 208 11 that that WDT cord-010398-5wot7tix 208 12 are be VBP cord-010398-5wot7tix 208 13 known know VBN cord-010398-5wot7tix 208 14 to to TO cord-010398-5wot7tix 208 15 affect affect VB cord-010398-5wot7tix 208 16 pain pain NN cord-010398-5wot7tix 208 17 and and CC cord-010398-5wot7tix 208 18 sensory sensory JJ cord-010398-5wot7tix 208 19 transmission transmission NN cord-010398-5wot7tix 208 20 also also RB cord-010398-5wot7tix 208 21 have have VBP cord-010398-5wot7tix 208 22 profound profound JJ cord-010398-5wot7tix 208 23 effects effect NNS cord-010398-5wot7tix 208 24 on on IN cord-010398-5wot7tix 208 25 energy energy NN cord-010398-5wot7tix 208 26 level level NN cord-010398-5wot7tix 208 27 and and CC cord-010398-5wot7tix 208 28 alertness alertness NN cord-010398-5wot7tix 208 29 , , , cord-010398-5wot7tix 208 30 sleep sleep NN cord-010398-5wot7tix 208 31 , , , cord-010398-5wot7tix 208 32 and and CC cord-010398-5wot7tix 208 33 other other JJ cord-010398-5wot7tix 208 34 related relate VBN cord-010398-5wot7tix 208 35 homeostatic homeostatic JJ cord-010398-5wot7tix 208 36 functions function NNS cord-010398-5wot7tix 208 37 . . . cord-010398-5wot7tix 209 1 Therefore therefore RB cord-010398-5wot7tix 209 2 , , , cord-010398-5wot7tix 209 3 it -PRON- PRP cord-010398-5wot7tix 209 4 is be VBZ cord-010398-5wot7tix 209 5 quite quite RB cord-010398-5wot7tix 209 6 conceivable conceivable JJ cord-010398-5wot7tix 209 7 that that IN cord-010398-5wot7tix 209 8 imbalances imbalance NNS cord-010398-5wot7tix 209 9 of of IN cord-010398-5wot7tix 209 10 neurotransmitters neurotransmitter NNS cord-010398-5wot7tix 209 11 in in IN cord-010398-5wot7tix 209 12 brain brain NN cord-010398-5wot7tix 209 13 neurotransmitters neurotransmitter NNS cord-010398-5wot7tix 209 14 that that WDT cord-010398-5wot7tix 209 15 are be VBP cord-010398-5wot7tix 209 16 believed believe VBN cord-010398-5wot7tix 209 17 to to TO cord-010398-5wot7tix 209 18 be be VB cord-010398-5wot7tix 209 19 playing play VBG cord-010398-5wot7tix 209 20 roles role NNS cord-010398-5wot7tix 209 21 in in IN cord-010398-5wot7tix 209 22 pain pain NN cord-010398-5wot7tix 209 23 transmission transmission NN cord-010398-5wot7tix 209 24 may may MD cord-010398-5wot7tix 209 25 be be VB cord-010398-5wot7tix 209 26 similarly similarly RB cord-010398-5wot7tix 209 27 leading lead VBG cord-010398-5wot7tix 209 28 to to IN cord-010398-5wot7tix 209 29 central central JJ cord-010398-5wot7tix 209 30 fatigue fatigue NN cord-010398-5wot7tix 209 31 and and CC cord-010398-5wot7tix 209 32 sleep sleep NN cord-010398-5wot7tix 209 33 disturbances disturbance NNS cord-010398-5wot7tix 209 34 when when WRB cord-010398-5wot7tix 209 35 these these DT cord-010398-5wot7tix 209 36 same same JJ cord-010398-5wot7tix 209 37 imbalances imbalance NNS cord-010398-5wot7tix 209 38 between between IN cord-010398-5wot7tix 209 39 excitatory excitatory JJ cord-010398-5wot7tix 209 40 and and CC cord-010398-5wot7tix 209 41 inhibitory inhibitory JJ cord-010398-5wot7tix 209 42 neurotransmitters neurotransmitter NNS cord-010398-5wot7tix 209 43 occur occur VBP cord-010398-5wot7tix 209 44 in in IN cord-010398-5wot7tix 209 45 brain brain NN cord-010398-5wot7tix 209 46 regions region NNS cord-010398-5wot7tix 209 47 that that WDT cord-010398-5wot7tix 209 48 control control VBP cord-010398-5wot7tix 209 49 these these DT cord-010398-5wot7tix 209 50 functions function NNS cord-010398-5wot7tix 209 51 in in IN cord-010398-5wot7tix 209 52 CFS CFS NNP cord-010398-5wot7tix 209 53 . . . cord-010398-5wot7tix 210 1 Because because IN cord-010398-5wot7tix 210 2 of of IN cord-010398-5wot7tix 210 3 the the DT cord-010398-5wot7tix 210 4 fact fact NN cord-010398-5wot7tix 210 5 that that IN cord-010398-5wot7tix 210 6 disparate disparate JJ cord-010398-5wot7tix 210 7 " " `` cord-010398-5wot7tix 210 8 stressors stressor NNS cord-010398-5wot7tix 210 9 " " '' cord-010398-5wot7tix 210 10 can can MD cord-010398-5wot7tix 210 11 trigger trigger VB cord-010398-5wot7tix 210 12 the the DT cord-010398-5wot7tix 210 13 development development NN cord-010398-5wot7tix 210 14 of of IN cord-010398-5wot7tix 210 15 these these DT cord-010398-5wot7tix 210 16 conditions condition NNS cord-010398-5wot7tix 210 17 , , , cord-010398-5wot7tix 210 18 the the DT cord-010398-5wot7tix 210 19 human human JJ cord-010398-5wot7tix 210 20 stress stress NN cord-010398-5wot7tix 210 21 response response NN cord-010398-5wot7tix 210 22 has have VBZ cord-010398-5wot7tix 210 23 been be VBN cord-010398-5wot7tix 210 24 closely closely RB cord-010398-5wot7tix 210 25 examined examine VBN cord-010398-5wot7tix 210 26 for for IN cord-010398-5wot7tix 210 27 a a DT cord-010398-5wot7tix 210 28 causative causative JJ cord-010398-5wot7tix 210 29 role role NN cord-010398-5wot7tix 210 30 . . . cord-010398-5wot7tix 211 1 These these DT cord-010398-5wot7tix 211 2 systems system NNS cord-010398-5wot7tix 211 3 are be VBP cord-010398-5wot7tix 211 4 mediated mediate VBN cord-010398-5wot7tix 211 5 primarily primarily RB cord-010398-5wot7tix 211 6 by by IN cord-010398-5wot7tix 211 7 the the DT cord-010398-5wot7tix 211 8 activity activity NN cord-010398-5wot7tix 211 9 of of IN cord-010398-5wot7tix 211 10 the the DT cord-010398-5wot7tix 211 11 corticotropinreleasing corticotropinrelease VBG cord-010398-5wot7tix 211 12 hormone hormone NN cord-010398-5wot7tix 211 13 nervous nervous JJ cord-010398-5wot7tix 211 14 system system NN cord-010398-5wot7tix 211 15 located locate VBN cord-010398-5wot7tix 211 16 in in IN cord-010398-5wot7tix 211 17 the the DT cord-010398-5wot7tix 211 18 hypothalamus hypothalamus NN cord-010398-5wot7tix 211 19 and and CC cord-010398-5wot7tix 211 20 locus locus NN cord-010398-5wot7tix 211 21 - - HYPH cord-010398-5wot7tix 211 22 ceruleus ceruleus NN cord-010398-5wot7tix 211 23 - - HYPH cord-010398-5wot7tix 211 24 norepinephrine norepinephrine NN cord-010398-5wot7tix 211 25 / / SYM cord-010398-5wot7tix 211 26 autonomic autonomic JJ cord-010398-5wot7tix 211 27 nervous nervous JJ cord-010398-5wot7tix 211 28 system system NN cord-010398-5wot7tix 211 29 in in IN cord-010398-5wot7tix 211 30 the the DT cord-010398-5wot7tix 211 31 brain brain NN cord-010398-5wot7tix 211 32 stem stem NN cord-010398-5wot7tix 211 33 . . . cord-010398-5wot7tix 212 1 Recent recent JJ cord-010398-5wot7tix 212 2 research research NN cord-010398-5wot7tix 212 3 suggests suggest VBZ cord-010398-5wot7tix 212 4 that that IN cord-010398-5wot7tix 212 5 although although IN cord-010398-5wot7tix 212 6 this this DT cord-010398-5wot7tix 212 7 system system NN cord-010398-5wot7tix 212 8 in in IN cord-010398-5wot7tix 212 9 humans human NNS cord-010398-5wot7tix 212 10 has have VBZ cord-010398-5wot7tix 212 11 been be VBN cord-010398-5wot7tix 212 12 highly highly RB cord-010398-5wot7tix 212 13 adaptive adaptive JJ cord-010398-5wot7tix 212 14 throughout throughout IN cord-010398-5wot7tix 212 15 history history NN cord-010398-5wot7tix 212 16 , , , cord-010398-5wot7tix 212 17 the the DT cord-010398-5wot7tix 212 18 stress stress NN cord-010398-5wot7tix 212 19 response response NN cord-010398-5wot7tix 212 20 may may MD cord-010398-5wot7tix 212 21 be be VB cord-010398-5wot7tix 212 22 inappropriately inappropriately RB cord-010398-5wot7tix 212 23 triggered trigger VBN cord-010398-5wot7tix 212 24 by by IN cord-010398-5wot7tix 212 25 a a DT cord-010398-5wot7tix 212 26 wide wide JJ cord-010398-5wot7tix 212 27 assortment assortment NN cord-010398-5wot7tix 212 28 of of IN cord-010398-5wot7tix 212 29 everyday everyday JJ cord-010398-5wot7tix 212 30 occurrences occurrence NNS cord-010398-5wot7tix 212 31 that that WDT cord-010398-5wot7tix 212 32 do do VBP cord-010398-5wot7tix 212 33 not not RB cord-010398-5wot7tix 212 34 pose pose VB cord-010398-5wot7tix 212 35 a a DT cord-010398-5wot7tix 212 36 real real JJ cord-010398-5wot7tix 212 37 threat threat NN cord-010398-5wot7tix 212 38 to to IN cord-010398-5wot7tix 212 39 survival survival NN cord-010398-5wot7tix 212 40 , , , cord-010398-5wot7tix 212 41 thus thus RB cord-010398-5wot7tix 212 42 initiating initiate VBG cord-010398-5wot7tix 212 43 the the DT cord-010398-5wot7tix 212 44 cascade cascade NN cord-010398-5wot7tix 212 45 of of IN cord-010398-5wot7tix 212 46 physiologic physiologic JJ cord-010398-5wot7tix 212 47 responses response NNS cord-010398-5wot7tix 212 48 more more RBR cord-010398-5wot7tix 212 49 frequently frequently RB cord-010398-5wot7tix 212 50 than than IN cord-010398-5wot7tix 212 51 can can MD cord-010398-5wot7tix 212 52 be be VB cord-010398-5wot7tix 212 53 tolerated tolerate VBN cord-010398-5wot7tix 212 54 [ [ -LRB- cord-010398-5wot7tix 212 55 117 117 CD cord-010398-5wot7tix 212 56 ] ] -RRB- cord-010398-5wot7tix 212 57 . . . cord-010398-5wot7tix 213 1 The the DT cord-010398-5wot7tix 213 2 type type NN cord-010398-5wot7tix 213 3 of of IN cord-010398-5wot7tix 213 4 stress stress NN cord-010398-5wot7tix 213 5 and and CC cord-010398-5wot7tix 213 6 the the DT cord-010398-5wot7tix 213 7 environment environment NN cord-010398-5wot7tix 213 8 in in IN cord-010398-5wot7tix 213 9 which which WDT cord-010398-5wot7tix 213 10 it -PRON- PRP cord-010398-5wot7tix 213 11 occurs occur VBZ cord-010398-5wot7tix 213 12 also also RB cord-010398-5wot7tix 213 13 have have VBP cord-010398-5wot7tix 213 14 an an DT cord-010398-5wot7tix 213 15 impact impact NN cord-010398-5wot7tix 213 16 on on IN cord-010398-5wot7tix 213 17 how how WRB cord-010398-5wot7tix 213 18 the the DT cord-010398-5wot7tix 213 19 stress stress NN cord-010398-5wot7tix 213 20 response response NN cord-010398-5wot7tix 213 21 is be VBZ cord-010398-5wot7tix 213 22 expressed express VBN cord-010398-5wot7tix 213 23 . . . cord-010398-5wot7tix 214 1 It -PRON- PRP cord-010398-5wot7tix 214 2 has have VBZ cord-010398-5wot7tix 214 3 been be VBN cord-010398-5wot7tix 214 4 noted note VBN cord-010398-5wot7tix 214 5 that that IN cord-010398-5wot7tix 214 6 victims victim NNS cord-010398-5wot7tix 214 7 of of IN cord-010398-5wot7tix 214 8 accidents accident NNS cord-010398-5wot7tix 214 9 experience experience VBP cord-010398-5wot7tix 214 10 a a DT cord-010398-5wot7tix 214 11 greater great JJR cord-010398-5wot7tix 214 12 frequency frequency NN cord-010398-5wot7tix 214 13 of of IN cord-010398-5wot7tix 214 14 FM FM NNP cord-010398-5wot7tix 214 15 and and CC cord-010398-5wot7tix 214 16 myofascial myofascial JJ cord-010398-5wot7tix 214 17 pain pain NN cord-010398-5wot7tix 214 18 than than IN cord-010398-5wot7tix 214 19 those those DT cord-010398-5wot7tix 214 20 who who WP cord-010398-5wot7tix 214 21 cause cause VBP cord-010398-5wot7tix 214 22 them -PRON- PRP cord-010398-5wot7tix 214 23 , , , cord-010398-5wot7tix 214 24 which which WDT cord-010398-5wot7tix 214 25 is be VBZ cord-010398-5wot7tix 214 26 congruent congruent JJ cord-010398-5wot7tix 214 27 with with IN cord-010398-5wot7tix 214 28 animal animal NN cord-010398-5wot7tix 214 29 studies study NNS cord-010398-5wot7tix 214 30 showing show VBG cord-010398-5wot7tix 214 31 that that IN cord-010398-5wot7tix 214 32 that that IN cord-010398-5wot7tix 214 33 the the DT cord-010398-5wot7tix 214 34 strongest strong JJS cord-010398-5wot7tix 214 35 physiological physiological JJ cord-010398-5wot7tix 214 36 responses response NNS cord-010398-5wot7tix 214 37 are be VBP cord-010398-5wot7tix 214 38 triggered trigger VBN cord-010398-5wot7tix 214 39 by by IN cord-010398-5wot7tix 214 40 events event NNS cord-010398-5wot7tix 214 41 that that WDT cord-010398-5wot7tix 214 42 are be VBP cord-010398-5wot7tix 214 43 accompanied accompany VBN cord-010398-5wot7tix 214 44 by by IN cord-010398-5wot7tix 214 45 a a DT cord-010398-5wot7tix 214 46 lack lack NN cord-010398-5wot7tix 214 47 of of IN cord-010398-5wot7tix 214 48 control control NN cord-010398-5wot7tix 214 49 or or CC cord-010398-5wot7tix 214 50 support support NN cord-010398-5wot7tix 214 51 and and CC cord-010398-5wot7tix 214 52 thus thus RB cord-010398-5wot7tix 214 53 viewed view VBN cord-010398-5wot7tix 214 54 as as IN cord-010398-5wot7tix 214 55 perceived perceive VBN cord-010398-5wot7tix 214 56 as as IN cord-010398-5wot7tix 214 57 inescapable inescapable JJ cord-010398-5wot7tix 214 58 or or CC cord-010398-5wot7tix 214 59 unavoidable unavoidable JJ cord-010398-5wot7tix 214 60 [ [ -LRB- cord-010398-5wot7tix 214 61 118 118 CD cord-010398-5wot7tix 214 62 ] ] -RRB- cord-010398-5wot7tix 214 63 . . . cord-010398-5wot7tix 215 1 In in IN cord-010398-5wot7tix 215 2 humans human NNS cord-010398-5wot7tix 215 3 , , , cord-010398-5wot7tix 215 4 daily daily RB cord-010398-5wot7tix 215 5 " " `` cord-010398-5wot7tix 215 6 hassles hassle NNS cord-010398-5wot7tix 215 7 " " '' cord-010398-5wot7tix 215 8 and and CC cord-010398-5wot7tix 215 9 personally personally RB cord-010398-5wot7tix 215 10 relevant relevant JJ cord-010398-5wot7tix 215 11 stressors stressor NNS cord-010398-5wot7tix 215 12 seem seem VBP cord-010398-5wot7tix 215 13 to to TO cord-010398-5wot7tix 215 14 be be VB cord-010398-5wot7tix 215 15 more more RBR cord-010398-5wot7tix 215 16 capable capable JJ cord-010398-5wot7tix 215 17 of of IN cord-010398-5wot7tix 215 18 causing cause VBG cord-010398-5wot7tix 215 19 symptoms symptom NNS cord-010398-5wot7tix 215 20 than than IN cord-010398-5wot7tix 215 21 major major JJ cord-010398-5wot7tix 215 22 catastrophic catastrophic JJ cord-010398-5wot7tix 215 23 events event NNS cord-010398-5wot7tix 215 24 that that WDT cord-010398-5wot7tix 215 25 do do VBP cord-010398-5wot7tix 215 26 not not RB cord-010398-5wot7tix 215 27 personally personally RB cord-010398-5wot7tix 215 28 impact impact VB cord-010398-5wot7tix 215 29 the the DT cord-010398-5wot7tix 215 30 individual individual NN cord-010398-5wot7tix 215 31 . . . cord-010398-5wot7tix 216 1 The the DT cord-010398-5wot7tix 216 2 authors author NNS cord-010398-5wot7tix 216 3 of of IN cord-010398-5wot7tix 216 4 2 2 CD cord-010398-5wot7tix 216 5 studies study NNS cord-010398-5wot7tix 216 6 performed perform VBN cord-010398-5wot7tix 216 7 in in IN cord-010398-5wot7tix 216 8 the the DT cord-010398-5wot7tix 216 9 United United NNP cord-010398-5wot7tix 216 10 States States NNP cord-010398-5wot7tix 216 11 just just RB cord-010398-5wot7tix 216 12 before before IN cord-010398-5wot7tix 216 13 and and CC cord-010398-5wot7tix 216 14 after after IN cord-010398-5wot7tix 216 15 the the DT cord-010398-5wot7tix 216 16 terrorist terrorist JJ cord-010398-5wot7tix 216 17 attacks attack NNS cord-010398-5wot7tix 216 18 of of IN cord-010398-5wot7tix 216 19 9/11 9/11 CD cord-010398-5wot7tix 216 20 point point NN cord-010398-5wot7tix 216 21 out out RP cord-010398-5wot7tix 216 22 that that IN cord-010398-5wot7tix 216 23 not not RB cord-010398-5wot7tix 216 24 all all DT cord-010398-5wot7tix 216 25 psychological psychological JJ cord-010398-5wot7tix 216 26 stress stress NN cord-010398-5wot7tix 216 27 is be VBZ cord-010398-5wot7tix 216 28 capable capable JJ cord-010398-5wot7tix 216 29 of of IN cord-010398-5wot7tix 216 30 triggering trigger VBG cord-010398-5wot7tix 216 31 or or CC cord-010398-5wot7tix 216 32 exacerbating exacerbate VBG cord-010398-5wot7tix 216 33 fatigue fatigue NN cord-010398-5wot7tix 216 34 , , , cord-010398-5wot7tix 216 35 pain pain NN cord-010398-5wot7tix 216 36 , , , cord-010398-5wot7tix 216 37 or or CC cord-010398-5wot7tix 216 38 other other JJ cord-010398-5wot7tix 216 39 somatic somatic JJ cord-010398-5wot7tix 216 40 symptoms symptom NNS cord-010398-5wot7tix 216 41 . . . cord-010398-5wot7tix 217 1 In in IN cord-010398-5wot7tix 217 2 one one CD cord-010398-5wot7tix 217 3 study study NN cord-010398-5wot7tix 217 4 performed perform VBN cord-010398-5wot7tix 217 5 by by IN cord-010398-5wot7tix 217 6 Raphael Raphael NNP cord-010398-5wot7tix 217 7 and and CC cord-010398-5wot7tix 217 8 colleagues colleague NNS cord-010398-5wot7tix 217 9 [ [ -LRB- cord-010398-5wot7tix 217 10 43 43 CD cord-010398-5wot7tix 217 11 ] ] -RRB- cord-010398-5wot7tix 217 12 , , , cord-010398-5wot7tix 217 13 no no DT cord-010398-5wot7tix 217 14 difference difference NN cord-010398-5wot7tix 217 15 in in IN cord-010398-5wot7tix 217 16 fatigue fatigue NN cord-010398-5wot7tix 217 17 , , , cord-010398-5wot7tix 217 18 pain pain NN cord-010398-5wot7tix 217 19 , , , cord-010398-5wot7tix 217 20 or or CC cord-010398-5wot7tix 217 21 other other JJ cord-010398-5wot7tix 217 22 somatic somatic JJ cord-010398-5wot7tix 217 23 symptoms symptom NNS cord-010398-5wot7tix 217 24 was be VBD cord-010398-5wot7tix 217 25 seen see VBN cord-010398-5wot7tix 217 26 in in IN cord-010398-5wot7tix 217 27 residents resident NNS cord-010398-5wot7tix 217 28 of of IN cord-010398-5wot7tix 217 29 New New NNP cord-010398-5wot7tix 217 30 York York NNP cord-010398-5wot7tix 217 31 and and CC cord-010398-5wot7tix 217 32 New New NNP cord-010398-5wot7tix 217 33 Jersey Jersey NNP cord-010398-5wot7tix 217 34 who who WP cord-010398-5wot7tix 217 35 had have VBD cord-010398-5wot7tix 217 36 been be VBN cord-010398-5wot7tix 217 37 surveyed survey VBN cord-010398-5wot7tix 217 38 before before IN cord-010398-5wot7tix 217 39 9/11 9/11 CD cord-010398-5wot7tix 217 40 and and CC cord-010398-5wot7tix 217 41 then then RB cord-010398-5wot7tix 217 42 just just RB cord-010398-5wot7tix 217 43 after after IN cord-010398-5wot7tix 217 44 the the DT cord-010398-5wot7tix 217 45 terrorist terrorist JJ cord-010398-5wot7tix 217 46 attacks attack NNS cord-010398-5wot7tix 217 47 on on IN cord-010398-5wot7tix 217 48 the the DT cord-010398-5wot7tix 217 49 World World NNP cord-010398-5wot7tix 217 50 Trade Trade NNP cord-010398-5wot7tix 217 51 Center Center NNP cord-010398-5wot7tix 217 52 . . . cord-010398-5wot7tix 218 1 In in IN cord-010398-5wot7tix 218 2 another another DT cord-010398-5wot7tix 218 3 study study NN cord-010398-5wot7tix 218 4 performed perform VBN cord-010398-5wot7tix 218 5 in in IN cord-010398-5wot7tix 218 6 the the DT cord-010398-5wot7tix 218 7 Washington Washington NNP cord-010398-5wot7tix 218 8 , , , cord-010398-5wot7tix 218 9 DC DC NNP cord-010398-5wot7tix 218 10 , , , cord-010398-5wot7tix 218 11 region region NN cord-010398-5wot7tix 218 12 ( ( -LRB- cord-010398-5wot7tix 218 13 near near IN cord-010398-5wot7tix 218 14 the the DT cord-010398-5wot7tix 218 15 Pentagon Pentagon NNP cord-010398-5wot7tix 218 16 ) ) -RRB- cord-010398-5wot7tix 218 17 during during IN cord-010398-5wot7tix 218 18 the the DT cord-010398-5wot7tix 218 19 same same JJ cord-010398-5wot7tix 218 20 time time NN cord-010398-5wot7tix 218 21 period period NN cord-010398-5wot7tix 218 22 , , , cord-010398-5wot7tix 218 23 patients patient NNS cord-010398-5wot7tix 218 24 with with IN cord-010398-5wot7tix 218 25 FM FM NNP cord-010398-5wot7tix 218 26 had have VBD cord-010398-5wot7tix 218 27 no no DT cord-010398-5wot7tix 218 28 worsening worsening NN cord-010398-5wot7tix 218 29 of of IN cord-010398-5wot7tix 218 30 pain pain NN cord-010398-5wot7tix 218 31 or or CC cord-010398-5wot7tix 218 32 other other JJ cord-010398-5wot7tix 218 33 somatic somatic JJ cord-010398-5wot7tix 218 34 symptoms symptom NNS cord-010398-5wot7tix 218 35 after after IN cord-010398-5wot7tix 218 36 the the DT cord-010398-5wot7tix 218 37 attacks attack NNS cord-010398-5wot7tix 218 38 compared compare VBN cord-010398-5wot7tix 218 39 with with IN cord-010398-5wot7tix 218 40 just just RB cord-010398-5wot7tix 218 41 before before IN cord-010398-5wot7tix 218 42 the the DT cord-010398-5wot7tix 218 43 attack attack NN cord-010398-5wot7tix 218 44 [ [ -LRB- cord-010398-5wot7tix 218 45 42 42 CD cord-010398-5wot7tix 218 46 ] ] -RRB- cord-010398-5wot7tix 218 47 . . . cord-010398-5wot7tix 219 1 Recent recent JJ cord-010398-5wot7tix 219 2 reviews review NNS cord-010398-5wot7tix 219 3 regarding regard VBG cord-010398-5wot7tix 219 4 the the DT cord-010398-5wot7tix 219 5 role role NN cord-010398-5wot7tix 219 6 that that IN cord-010398-5wot7tix 219 7 " " `` cord-010398-5wot7tix 219 8 stressors stressor NNS cord-010398-5wot7tix 219 9 " " '' cord-010398-5wot7tix 219 10 ( ( -LRB- cord-010398-5wot7tix 219 11 eg eg NNS cord-010398-5wot7tix 219 12 , , , cord-010398-5wot7tix 219 13 infections infection NNS cord-010398-5wot7tix 219 14 , , , cord-010398-5wot7tix 219 15 physical physical JJ cord-010398-5wot7tix 219 16 trauma trauma NN cord-010398-5wot7tix 219 17 , , , cord-010398-5wot7tix 219 18 emotional emotional JJ cord-010398-5wot7tix 219 19 stress stress NN cord-010398-5wot7tix 219 20 ) ) -RRB- cord-010398-5wot7tix 219 21 or or CC cord-010398-5wot7tix 219 22 catastrophic catastrophic JJ cord-010398-5wot7tix 219 23 events event NNS cord-010398-5wot7tix 219 24 may may MD cord-010398-5wot7tix 219 25 have have VB cord-010398-5wot7tix 219 26 in in IN cord-010398-5wot7tix 219 27 triggering trigger VBG cord-010398-5wot7tix 219 28 the the DT cord-010398-5wot7tix 219 29 development development NN cord-010398-5wot7tix 219 30 of of IN cord-010398-5wot7tix 219 31 CFS CFS NNP cord-010398-5wot7tix 219 32 , , , cord-010398-5wot7tix 219 33 FM FM NNP cord-010398-5wot7tix 219 34 , , , cord-010398-5wot7tix 219 35 or or CC cord-010398-5wot7tix 219 36 related relate VBN cord-010398-5wot7tix 219 37 conditions condition NNS cord-010398-5wot7tix 219 38 have have VBP cord-010398-5wot7tix 219 39 identified identify VBN cord-010398-5wot7tix 219 40 several several JJ cord-010398-5wot7tix 219 41 factors factor NNS cord-010398-5wot7tix 219 42 that that WDT cord-010398-5wot7tix 219 43 may may MD cord-010398-5wot7tix 219 44 be be VB cord-010398-5wot7tix 219 45 much much RB cord-010398-5wot7tix 219 46 more more RBR cord-010398-5wot7tix 219 47 important important JJ cord-010398-5wot7tix 219 48 than than IN cord-010398-5wot7tix 219 49 the the DT cord-010398-5wot7tix 219 50 intensity intensity NN cord-010398-5wot7tix 219 51 of of IN cord-010398-5wot7tix 219 52 the the DT cord-010398-5wot7tix 219 53 " " `` cord-010398-5wot7tix 219 54 stressor stressor NN cord-010398-5wot7tix 219 55 " " '' cord-010398-5wot7tix 219 56 in in IN cord-010398-5wot7tix 219 57 predicting predict VBG cord-010398-5wot7tix 219 58 adverse adverse JJ cord-010398-5wot7tix 219 59 health health NN cord-010398-5wot7tix 219 60 outcomes outcome NNS cord-010398-5wot7tix 219 61 . . . cord-010398-5wot7tix 220 1 Female female JJ cord-010398-5wot7tix 220 2 gender gender NN cord-010398-5wot7tix 220 3 , , , cord-010398-5wot7tix 220 4 worry worry NN cord-010398-5wot7tix 220 5 or or CC cord-010398-5wot7tix 220 6 expectation expectation NN cord-010398-5wot7tix 220 7 of of IN cord-010398-5wot7tix 220 8 chronicity chronicity NN cord-010398-5wot7tix 220 9 , , , cord-010398-5wot7tix 220 10 lack lack NN cord-010398-5wot7tix 220 11 of of IN cord-010398-5wot7tix 220 12 control control NN cord-010398-5wot7tix 220 13 of of IN cord-010398-5wot7tix 220 14 the the DT cord-010398-5wot7tix 220 15 stressor stressor NN cord-010398-5wot7tix 220 16 , , , cord-010398-5wot7tix 220 17 intensity intensity NN cord-010398-5wot7tix 220 18 of of IN cord-010398-5wot7tix 220 19 the the DT cord-010398-5wot7tix 220 20 initial initial JJ cord-010398-5wot7tix 220 21 symptoms symptom NNS cord-010398-5wot7tix 220 22 , , , cord-010398-5wot7tix 220 23 and and CC cord-010398-5wot7tix 220 24 inactivity inactivity NN cord-010398-5wot7tix 220 25 or or CC cord-010398-5wot7tix 220 26 time time NN cord-010398-5wot7tix 220 27 off off IN cord-010398-5wot7tix 220 28 work work NN cord-010398-5wot7tix 220 29 after after IN cord-010398-5wot7tix 220 30 the the DT cord-010398-5wot7tix 220 31 stressor stressor NN cord-010398-5wot7tix 220 32 make make VBP cord-010398-5wot7tix 220 33 it -PRON- PRP cord-010398-5wot7tix 220 34 more more RBR cord-010398-5wot7tix 220 35 likely likely JJ cord-010398-5wot7tix 220 36 to to TO cord-010398-5wot7tix 220 37 trigger trigger VB cord-010398-5wot7tix 220 38 the the DT cord-010398-5wot7tix 220 39 development development NN cord-010398-5wot7tix 220 40 of of IN cord-010398-5wot7tix 220 41 pain pain NN cord-010398-5wot7tix 220 42 , , , cord-010398-5wot7tix 220 43 fatigue fatigue NN cord-010398-5wot7tix 220 44 , , , cord-010398-5wot7tix 220 45 or or CC cord-010398-5wot7tix 220 46 other other JJ cord-010398-5wot7tix 220 47 somatic somatic JJ cord-010398-5wot7tix 220 48 symptoms symptom NNS cord-010398-5wot7tix 220 49 [ [ -LRB- cord-010398-5wot7tix 220 50 119 119 CD cord-010398-5wot7tix 220 51 ] ] -RRB- cord-010398-5wot7tix 220 52 . . . cord-010398-5wot7tix 221 1 Naturally naturally RB cord-010398-5wot7tix 221 2 occurring occur VBG cord-010398-5wot7tix 221 3 catastrophic catastrophic JJ cord-010398-5wot7tix 221 4 events event NNS cord-010398-5wot7tix 221 5 such such JJ cord-010398-5wot7tix 221 6 as as IN cord-010398-5wot7tix 221 7 earthquakes earthquake NNS cord-010398-5wot7tix 221 8 , , , cord-010398-5wot7tix 221 9 floods flood NNS cord-010398-5wot7tix 221 10 , , , cord-010398-5wot7tix 221 11 or or CC cord-010398-5wot7tix 221 12 fires fire NNS cord-010398-5wot7tix 221 13 are be VBP cord-010398-5wot7tix 221 14 much much RB cord-010398-5wot7tix 221 15 less less RBR cord-010398-5wot7tix 221 16 likely likely JJ cord-010398-5wot7tix 221 17 to to TO cord-010398-5wot7tix 221 18 lead lead VB cord-010398-5wot7tix 221 19 to to IN cord-010398-5wot7tix 221 20 chronic chronic JJ cord-010398-5wot7tix 221 21 somatic somatic JJ cord-010398-5wot7tix 221 22 symptoms symptom NNS cord-010398-5wot7tix 221 23 than than IN cord-010398-5wot7tix 221 24 similarly similarly RB cord-010398-5wot7tix 221 25 stressful stressful JJ cord-010398-5wot7tix 221 26 events event NNS cord-010398-5wot7tix 221 27 that that WDT cord-010398-5wot7tix 221 28 are be VBP cord-010398-5wot7tix 221 29 " " `` cord-010398-5wot7tix 221 30 human human NN cord-010398-5wot7tix 221 31 - - HYPH cord-010398-5wot7tix 221 32 made make VBN cord-010398-5wot7tix 221 33 , , , cord-010398-5wot7tix 221 34 " " '' cord-010398-5wot7tix 221 35 such such JJ cord-010398-5wot7tix 221 36 as as IN cord-010398-5wot7tix 221 37 chemical chemical NN cord-010398-5wot7tix 221 38 spills spill NNS cord-010398-5wot7tix 221 39 , , , cord-010398-5wot7tix 221 40 or or CC cord-010398-5wot7tix 221 41 war war NN cord-010398-5wot7tix 221 42 [ [ -LRB- cord-010398-5wot7tix 221 43 120 120 CD cord-010398-5wot7tix 221 44 ] ] -RRB- cord-010398-5wot7tix 221 45 . . . cord-010398-5wot7tix 222 1 Being be VBG cord-010398-5wot7tix 222 2 exposed expose VBN cord-010398-5wot7tix 222 3 to to IN cord-010398-5wot7tix 222 4 a a DT cord-010398-5wot7tix 222 5 multitude multitude NN cord-010398-5wot7tix 222 6 of of IN cord-010398-5wot7tix 222 7 stressors stressor NNS cord-010398-5wot7tix 222 8 simultaneously simultaneously RB cord-010398-5wot7tix 222 9 , , , cord-010398-5wot7tix 222 10 or or CC cord-010398-5wot7tix 222 11 during during IN cord-010398-5wot7tix 222 12 a a DT cord-010398-5wot7tix 222 13 period period NN cord-010398-5wot7tix 222 14 of of IN cord-010398-5wot7tix 222 15 time time NN cord-010398-5wot7tix 222 16 , , , cord-010398-5wot7tix 222 17 may may MD cord-010398-5wot7tix 222 18 also also RB cord-010398-5wot7tix 222 19 be be VB cord-010398-5wot7tix 222 20 a a DT cord-010398-5wot7tix 222 21 significant significant JJ cord-010398-5wot7tix 222 22 risk risk NN cord-010398-5wot7tix 222 23 for for IN cord-010398-5wot7tix 222 24 later later JJ cord-010398-5wot7tix 222 25 somatic somatic JJ cord-010398-5wot7tix 222 26 symptoms symptom NNS cord-010398-5wot7tix 222 27 and and CC cord-010398-5wot7tix 222 28 or or CC cord-010398-5wot7tix 222 29 psychological psychological JJ cord-010398-5wot7tix 222 30 sequelae sequela NNS cord-010398-5wot7tix 222 31 . . . cord-010398-5wot7tix 223 1 Intensely intensely RB cord-010398-5wot7tix 223 2 stressful stressful JJ cord-010398-5wot7tix 223 3 events event NNS cord-010398-5wot7tix 223 4 can can MD cord-010398-5wot7tix 223 5 lead lead VB cord-010398-5wot7tix 223 6 to to IN cord-010398-5wot7tix 223 7 permanent permanent JJ cord-010398-5wot7tix 223 8 changes change NNS cord-010398-5wot7tix 223 9 in in IN cord-010398-5wot7tix 223 10 the the DT cord-010398-5wot7tix 223 11 activity activity NN cord-010398-5wot7tix 223 12 of of IN cord-010398-5wot7tix 223 13 both both DT cord-010398-5wot7tix 223 14 mouse mouse NN cord-010398-5wot7tix 223 15 and and CC cord-010398-5wot7tix 223 16 human human JJ cord-010398-5wot7tix 223 17 stress stress NN cord-010398-5wot7tix 223 18 response response NN cord-010398-5wot7tix 223 19 systems system NNS cord-010398-5wot7tix 223 20 [ [ -LRB- cord-010398-5wot7tix 223 21 117 117 CD cord-010398-5wot7tix 223 22 , , , cord-010398-5wot7tix 223 23 121 121 CD cord-010398-5wot7tix 223 24 ] ] -RRB- cord-010398-5wot7tix 223 25 . . . cord-010398-5wot7tix 224 1 This this DT cord-010398-5wot7tix 224 2 link link NN cord-010398-5wot7tix 224 3 between between IN cord-010398-5wot7tix 224 4 exposure exposure NN cord-010398-5wot7tix 224 5 to to IN cord-010398-5wot7tix 224 6 " " `` cord-010398-5wot7tix 224 7 stressors stressor NNS cord-010398-5wot7tix 224 8 " " '' cord-010398-5wot7tix 224 9 and and CC cord-010398-5wot7tix 224 10 the the DT cord-010398-5wot7tix 224 11 subsequent subsequent JJ cord-010398-5wot7tix 224 12 development development NN cord-010398-5wot7tix 224 13 of of IN cord-010398-5wot7tix 224 14 CFS CFS NNP cord-010398-5wot7tix 224 15 and and CC cord-010398-5wot7tix 224 16 FM FM NNP cord-010398-5wot7tix 224 17 led lead VBD cord-010398-5wot7tix 224 18 to to IN cord-010398-5wot7tix 224 19 studies study NNS cord-010398-5wot7tix 224 20 of of IN cord-010398-5wot7tix 224 21 human human JJ cord-010398-5wot7tix 224 22 stress stress NN cord-010398-5wot7tix 224 23 systems system NNS cord-010398-5wot7tix 224 24 in in IN cord-010398-5wot7tix 224 25 this this DT cord-010398-5wot7tix 224 26 condition condition NN cord-010398-5wot7tix 224 27 . . . cord-010398-5wot7tix 225 1 These these DT cord-010398-5wot7tix 225 2 studies study NNS cord-010398-5wot7tix 225 3 have have VBP cord-010398-5wot7tix 225 4 generally generally RB cord-010398-5wot7tix 225 5 shown show VBN cord-010398-5wot7tix 225 6 alterations alteration NNS cord-010398-5wot7tix 225 7 of of IN cord-010398-5wot7tix 225 8 the the DT cord-010398-5wot7tix 225 9 hypothalamic hypothalamic JJ cord-010398-5wot7tix 225 10 - - HYPH cord-010398-5wot7tix 225 11 pituitary pituitary NN cord-010398-5wot7tix 225 12 - - HYPH cord-010398-5wot7tix 225 13 adrenal adrenal NN cord-010398-5wot7tix 225 14 ( ( -LRB- cord-010398-5wot7tix 225 15 HPA HPA NNP cord-010398-5wot7tix 225 16 ) ) -RRB- cord-010398-5wot7tix 225 17 axis axis NN cord-010398-5wot7tix 225 18 and and CC cord-010398-5wot7tix 225 19 the the DT cord-010398-5wot7tix 225 20 sympathetic sympathetic JJ cord-010398-5wot7tix 225 21 nervous nervous JJ cord-010398-5wot7tix 225 22 system system NN cord-010398-5wot7tix 225 23 in in IN cord-010398-5wot7tix 225 24 CFS cfs NN cord-010398-5wot7tix 225 25 and and CC cord-010398-5wot7tix 225 26 related related JJ cord-010398-5wot7tix 225 27 conditions condition NNS cord-010398-5wot7tix 225 28 [ [ -LRB- cord-010398-5wot7tix 225 29 122 122 CD cord-010398-5wot7tix 225 30 ] ] -RRB- cord-010398-5wot7tix 225 31 [ [ -LRB- cord-010398-5wot7tix 225 32 123 123 CD cord-010398-5wot7tix 225 33 ] ] -RRB- cord-010398-5wot7tix 225 34 [ [ -LRB- cord-010398-5wot7tix 225 35 124 124 CD cord-010398-5wot7tix 225 36 ] ] -RRB- cord-010398-5wot7tix 225 37 [ [ -LRB- cord-010398-5wot7tix 225 38 125 125 CD cord-010398-5wot7tix 225 39 ] ] -RRB- cord-010398-5wot7tix 225 40 [ [ -LRB- cord-010398-5wot7tix 225 41 126 126 CD cord-010398-5wot7tix 225 42 ] ] -RRB- cord-010398-5wot7tix 225 43 [ [ -LRB- cord-010398-5wot7tix 225 44 127 127 CD cord-010398-5wot7tix 225 45 ] ] -RRB- cord-010398-5wot7tix 225 46 . . . cord-010398-5wot7tix 226 1 Although although IN cord-010398-5wot7tix 226 2 these these DT cord-010398-5wot7tix 226 3 studies study NNS cord-010398-5wot7tix 226 4 often often RB cord-010398-5wot7tix 226 5 note note VBP cord-010398-5wot7tix 226 6 either either CC cord-010398-5wot7tix 226 7 hypo hypo NN cord-010398-5wot7tix 226 8 - - : cord-010398-5wot7tix 226 9 or or CC cord-010398-5wot7tix 226 10 hyperactivity hyperactivity NN cord-010398-5wot7tix 226 11 of of IN cord-010398-5wot7tix 226 12 both both CC cord-010398-5wot7tix 226 13 the the DT cord-010398-5wot7tix 226 14 HPA HPA NNP cord-010398-5wot7tix 226 15 axis axis NN cord-010398-5wot7tix 226 16 and and CC cord-010398-5wot7tix 226 17 sympathetic sympathetic JJ cord-010398-5wot7tix 226 18 nervous nervous JJ cord-010398-5wot7tix 226 19 system system NN cord-010398-5wot7tix 226 20 in in IN cord-010398-5wot7tix 226 21 patients patient NNS cord-010398-5wot7tix 226 22 with with IN cord-010398-5wot7tix 226 23 FM FM NNP cord-010398-5wot7tix 226 24 and and CC cord-010398-5wot7tix 226 25 related relate VBN cord-010398-5wot7tix 226 26 conditions condition NNS cord-010398-5wot7tix 226 27 , , , cord-010398-5wot7tix 226 28 the the DT cord-010398-5wot7tix 226 29 precise precise JJ cord-010398-5wot7tix 226 30 abnormality abnormality NN cord-010398-5wot7tix 226 31 varies vary VBZ cord-010398-5wot7tix 226 32 from from IN cord-010398-5wot7tix 226 33 study study NN cord-010398-5wot7tix 226 34 to to TO cord-010398-5wot7tix 226 35 study study VB cord-010398-5wot7tix 226 36 . . . cord-010398-5wot7tix 227 1 Moreover moreover RB cord-010398-5wot7tix 227 2 , , , cord-010398-5wot7tix 227 3 these these DT cord-010398-5wot7tix 227 4 studies study NNS cord-010398-5wot7tix 227 5 only only RB cord-010398-5wot7tix 227 6 find find VBP cord-010398-5wot7tix 227 7 " " `` cord-010398-5wot7tix 227 8 abnormal abnormal JJ cord-010398-5wot7tix 227 9 " " '' cord-010398-5wot7tix 227 10 HPA hpa NN cord-010398-5wot7tix 227 11 or or CC cord-010398-5wot7tix 227 12 autonomic autonomic JJ cord-010398-5wot7tix 227 13 function function NN cord-010398-5wot7tix 227 14 in in IN cord-010398-5wot7tix 227 15 a a DT cord-010398-5wot7tix 227 16 very very RB cord-010398-5wot7tix 227 17 small small JJ cord-010398-5wot7tix 227 18 percentage percentage NN cord-010398-5wot7tix 227 19 of of IN cord-010398-5wot7tix 227 20 patients patient NNS cord-010398-5wot7tix 227 21 , , , cord-010398-5wot7tix 227 22 and and CC cord-010398-5wot7tix 227 23 there there EX cord-010398-5wot7tix 227 24 is be VBZ cord-010398-5wot7tix 227 25 tremendous tremendous JJ cord-010398-5wot7tix 227 26 overlap overlap NN cord-010398-5wot7tix 227 27 between between IN cord-010398-5wot7tix 227 28 patients patient NNS cord-010398-5wot7tix 227 29 and and CC cord-010398-5wot7tix 227 30 control control VB cord-010398-5wot7tix 227 31 patients patient NNS cord-010398-5wot7tix 227 32 in in IN cord-010398-5wot7tix 227 33 these these DT cord-010398-5wot7tix 227 34 studies study NNS cord-010398-5wot7tix 227 35 . . . cord-010398-5wot7tix 228 1 The the DT cord-010398-5wot7tix 228 2 best good JJS cord-010398-5wot7tix 228 3 recent recent JJ cord-010398-5wot7tix 228 4 studies study NNS cord-010398-5wot7tix 228 5 of of IN cord-010398-5wot7tix 228 6 the the DT cord-010398-5wot7tix 228 7 HPA HPA NNP cord-010398-5wot7tix 228 8 axis axis NN cord-010398-5wot7tix 228 9 in in IN cord-010398-5wot7tix 228 10 CFS CFS NNP cord-010398-5wot7tix 228 11 provide provide VBP cord-010398-5wot7tix 228 12 continued continued JJ cord-010398-5wot7tix 228 13 support support NN cord-010398-5wot7tix 228 14 for for IN cord-010398-5wot7tix 228 15 enhanced enhanced JJ cord-010398-5wot7tix 228 16 glucocorticoid glucocorticoid JJ cord-010398-5wot7tix 228 17 negative negative JJ cord-010398-5wot7tix 228 18 feedback feedback NN cord-010398-5wot7tix 228 19 and/or and/or CC cord-010398-5wot7tix 228 20 a a DT cord-010398-5wot7tix 228 21 reduced reduce VBN cord-010398-5wot7tix 228 22 central central JJ cord-010398-5wot7tix 228 23 HPA HPA NNP cord-010398-5wot7tix 228 24 axis axis NN cord-010398-5wot7tix 228 25 drive drive NN cord-010398-5wot7tix 228 26 in in IN cord-010398-5wot7tix 228 27 groups group NNS cord-010398-5wot7tix 228 28 of of IN cord-010398-5wot7tix 228 29 patients patient NNS cord-010398-5wot7tix 228 30 with with IN cord-010398-5wot7tix 228 31 CFS CFS NNP cord-010398-5wot7tix 228 32 , , , cord-010398-5wot7tix 228 33 but but CC cord-010398-5wot7tix 228 34 they -PRON- PRP cord-010398-5wot7tix 228 35 point point VBP cord-010398-5wot7tix 228 36 out out RP cord-010398-5wot7tix 228 37 a a DT cord-010398-5wot7tix 228 38 very very RB cord-010398-5wot7tix 228 39 important important JJ cord-010398-5wot7tix 228 40 confound confound NN cord-010398-5wot7tix 228 41 in in IN cord-010398-5wot7tix 228 42 studying study VBG cord-010398-5wot7tix 228 43 HPA HPA NNP cord-010398-5wot7tix 228 44 function function NN cord-010398-5wot7tix 228 45 : : : cord-010398-5wot7tix 228 46 early early JJ cord-010398-5wot7tix 228 47 life life NN cord-010398-5wot7tix 228 48 stress stress NN cord-010398-5wot7tix 228 49 . . . cord-010398-5wot7tix 229 1 Heim Heim NNP cord-010398-5wot7tix 229 2 and and CC cord-010398-5wot7tix 229 3 others other NNS cord-010398-5wot7tix 229 4 have have VBP cord-010398-5wot7tix 229 5 shown show VBN cord-010398-5wot7tix 229 6 that that IN cord-010398-5wot7tix 229 7 early early JJ cord-010398-5wot7tix 229 8 life life NN cord-010398-5wot7tix 229 9 stress stress NN cord-010398-5wot7tix 229 10 may may MD cord-010398-5wot7tix 229 11 lead lead VB cord-010398-5wot7tix 229 12 to to IN cord-010398-5wot7tix 229 13 permanent permanent JJ cord-010398-5wot7tix 229 14 changes change NNS cord-010398-5wot7tix 229 15 in in IN cord-010398-5wot7tix 229 16 HPA HPA NNP cord-010398-5wot7tix 229 17 functions function NNS cord-010398-5wot7tix 229 18 in in IN cord-010398-5wot7tix 229 19 humans human NNS cord-010398-5wot7tix 229 20 , , , cord-010398-5wot7tix 229 21 and and CC cord-010398-5wot7tix 229 22 recent recent JJ cord-010398-5wot7tix 229 23 studies study NNS cord-010398-5wot7tix 229 24 have have VBP cord-010398-5wot7tix 229 25 suggested suggest VBN cord-010398-5wot7tix 229 26 that that IN cord-010398-5wot7tix 229 27 the the DT cord-010398-5wot7tix 229 28 presence presence NN cord-010398-5wot7tix 229 29 or or CC cord-010398-5wot7tix 229 30 absence absence NN cord-010398-5wot7tix 229 31 of of IN cord-010398-5wot7tix 229 32 early early JJ cord-010398-5wot7tix 229 33 life life NN cord-010398-5wot7tix 229 34 stress stress NN cord-010398-5wot7tix 229 35 was be VBD cord-010398-5wot7tix 229 36 a a DT cord-010398-5wot7tix 229 37 potent potent JJ cord-010398-5wot7tix 229 38 predictor predictor NN cord-010398-5wot7tix 229 39 of of IN cord-010398-5wot7tix 229 40 HPA HPA NNP cord-010398-5wot7tix 229 41 function function NN cord-010398-5wot7tix 229 42 in in IN cord-010398-5wot7tix 229 43 both both CC cord-010398-5wot7tix 229 44 CFS CFS NNP cord-010398-5wot7tix 229 45 and and CC cord-010398-5wot7tix 229 46 population population NN cord-010398-5wot7tix 229 47 - - HYPH cord-010398-5wot7tix 229 48 based base VBN cord-010398-5wot7tix 229 49 studies study NNS cord-010398-5wot7tix 229 50 [ [ -LRB- cord-010398-5wot7tix 229 51 128 128 CD cord-010398-5wot7tix 229 52 , , , cord-010398-5wot7tix 229 53 129 129 CD cord-010398-5wot7tix 229 54 ] ] -RRB- cord-010398-5wot7tix 229 55 . . . cord-010398-5wot7tix 230 1 Similar similar JJ cord-010398-5wot7tix 230 2 findings finding NNS cord-010398-5wot7tix 230 3 have have VBP cord-010398-5wot7tix 230 4 been be VBN cord-010398-5wot7tix 230 5 noted note VBN cord-010398-5wot7tix 230 6 with with IN cord-010398-5wot7tix 230 7 FM FM NNP cord-010398-5wot7tix 230 8 patients patient NNS cord-010398-5wot7tix 230 9 , , , cord-010398-5wot7tix 230 10 demonstrating demonstrate VBG cord-010398-5wot7tix 230 11 that that IN cord-010398-5wot7tix 230 12 the the DT cord-010398-5wot7tix 230 13 presence presence NN cord-010398-5wot7tix 230 14 or or CC cord-010398-5wot7tix 230 15 absence absence NN cord-010398-5wot7tix 230 16 of of IN cord-010398-5wot7tix 230 17 early early JJ cord-010398-5wot7tix 230 18 life life NN cord-010398-5wot7tix 230 19 stress stress NN cord-010398-5wot7tix 230 20 influenced influence VBD cord-010398-5wot7tix 230 21 CSF CSF NNP cord-010398-5wot7tix 230 22 levels level NNS cord-010398-5wot7tix 230 23 of of IN cord-010398-5wot7tix 230 24 corticotropin corticotropin NNP cord-010398-5wot7tix 230 25 - - HYPH cord-010398-5wot7tix 230 26 releasing release VBG cord-010398-5wot7tix 230 27 hormone hormone NN cord-010398-5wot7tix 230 28 more more RBR cord-010398-5wot7tix 230 29 strongly strongly RB cord-010398-5wot7tix 230 30 than than IN cord-010398-5wot7tix 230 31 any any DT cord-010398-5wot7tix 230 32 other other JJ cord-010398-5wot7tix 230 33 factor factor NN cord-010398-5wot7tix 230 34 [ [ -LRB- cord-010398-5wot7tix 230 35 130 130 CD cord-010398-5wot7tix 230 36 ] ] -RRB- cord-010398-5wot7tix 230 37 . . . cord-010398-5wot7tix 231 1 Studies study NNS cord-010398-5wot7tix 231 2 in in IN cord-010398-5wot7tix 231 3 FM FM NNP cord-010398-5wot7tix 231 4 suggest suggest VBP cord-010398-5wot7tix 231 5 that that IN cord-010398-5wot7tix 231 6 HPA HPA NNP cord-010398-5wot7tix 231 7 function function NN cord-010398-5wot7tix 231 8 is be VBZ cord-010398-5wot7tix 231 9 related relate VBN cord-010398-5wot7tix 231 10 to to IN cord-010398-5wot7tix 231 11 levels level NNS cord-010398-5wot7tix 231 12 of of IN cord-010398-5wot7tix 231 13 pain pain NN cord-010398-5wot7tix 231 14 but but CC cord-010398-5wot7tix 231 15 not not RB cord-010398-5wot7tix 231 16 fatigue fatigue NN cord-010398-5wot7tix 231 17 [ [ -LRB- cord-010398-5wot7tix 231 18 131 131 CD cord-010398-5wot7tix 231 19 ] ] -RRB- cord-010398-5wot7tix 231 20 . . . cord-010398-5wot7tix 232 1 In in IN cord-010398-5wot7tix 232 2 fact fact NN cord-010398-5wot7tix 232 3 , , , cord-010398-5wot7tix 232 4 HPA HPA NNP cord-010398-5wot7tix 232 5 findings finding NNS cord-010398-5wot7tix 232 6 in in IN cord-010398-5wot7tix 232 7 groups group NNS cord-010398-5wot7tix 232 8 of of IN cord-010398-5wot7tix 232 9 patients patient NNS cord-010398-5wot7tix 232 10 with with IN cord-010398-5wot7tix 232 11 CFS CFS NNP cord-010398-5wot7tix 232 12 have have VBP cord-010398-5wot7tix 232 13 not not RB cord-010398-5wot7tix 232 14 been be VBN cord-010398-5wot7tix 232 15 found find VBN cord-010398-5wot7tix 232 16 to to TO cord-010398-5wot7tix 232 17 be be VB cord-010398-5wot7tix 232 18 related relate VBN cord-010398-5wot7tix 232 19 to to IN cord-010398-5wot7tix 232 20 levels level NNS cord-010398-5wot7tix 232 21 of of IN cord-010398-5wot7tix 232 22 fatigue fatigue NN cord-010398-5wot7tix 232 23 . . . cord-010398-5wot7tix 233 1 Changes change NNS cord-010398-5wot7tix 233 2 in in IN cord-010398-5wot7tix 233 3 baseline baseline JJ cord-010398-5wot7tix 233 4 function function NN cord-010398-5wot7tix 233 5 of of IN cord-010398-5wot7tix 233 6 the the DT cord-010398-5wot7tix 233 7 stress stress NN cord-010398-5wot7tix 233 8 response response NN cord-010398-5wot7tix 233 9 that that WDT cord-010398-5wot7tix 233 10 may may MD cord-010398-5wot7tix 233 11 occur occur VB cord-010398-5wot7tix 233 12 after after IN cord-010398-5wot7tix 233 13 a a DT cord-010398-5wot7tix 233 14 stressor stressor NN cord-010398-5wot7tix 233 15 earlier early RBR cord-010398-5wot7tix 233 16 in in IN cord-010398-5wot7tix 233 17 life life NN cord-010398-5wot7tix 233 18 have have VBP cord-010398-5wot7tix 233 19 been be VBN cord-010398-5wot7tix 233 20 shown show VBN cord-010398-5wot7tix 233 21 to to TO cord-010398-5wot7tix 233 22 predict predict VB cord-010398-5wot7tix 233 23 which which WDT cord-010398-5wot7tix 233 24 symptom symptom NN cord-010398-5wot7tix 233 25 - - HYPH cord-010398-5wot7tix 233 26 free free JJ cord-010398-5wot7tix 233 27 patients patient NNS cord-010398-5wot7tix 233 28 without without IN cord-010398-5wot7tix 233 29 chronic chronic JJ cord-010398-5wot7tix 233 30 pain pain NN cord-010398-5wot7tix 233 31 or or CC cord-010398-5wot7tix 233 32 other other JJ cord-010398-5wot7tix 233 33 somatic somatic JJ cord-010398-5wot7tix 233 34 symptoms symptom NNS cord-010398-5wot7tix 233 35 are be VBP cord-010398-5wot7tix 233 36 more more RBR cord-010398-5wot7tix 233 37 likely likely JJ cord-010398-5wot7tix 233 38 to to TO cord-010398-5wot7tix 233 39 develop develop VB cord-010398-5wot7tix 233 40 these these DT cord-010398-5wot7tix 233 41 somatic somatic JJ cord-010398-5wot7tix 233 42 symptoms symptom NNS cord-010398-5wot7tix 233 43 . . . cord-010398-5wot7tix 234 1 This this DT cord-010398-5wot7tix 234 2 has have VBZ cord-010398-5wot7tix 234 3 been be VBN cord-010398-5wot7tix 234 4 noted note VBN cord-010398-5wot7tix 234 5 both both CC cord-010398-5wot7tix 234 6 in in IN cord-010398-5wot7tix 234 7 populationbased populationbased JJ cord-010398-5wot7tix 234 8 studies study NNS cord-010398-5wot7tix 234 9 and and CC cord-010398-5wot7tix 234 10 in in IN cord-010398-5wot7tix 234 11 experiments experiment NNS cord-010398-5wot7tix 234 12 in in IN cord-010398-5wot7tix 234 13 which which WDT cord-010398-5wot7tix 234 14 healthy healthy JJ cord-010398-5wot7tix 234 15 young young JJ cord-010398-5wot7tix 234 16 adults adult NNS cord-010398-5wot7tix 234 17 are be VBP cord-010398-5wot7tix 234 18 deprived deprive VBN cord-010398-5wot7tix 234 19 of of IN cord-010398-5wot7tix 234 20 regular regular JJ cord-010398-5wot7tix 234 21 sleep sleep NN cord-010398-5wot7tix 234 22 or or CC cord-010398-5wot7tix 234 23 exercise exercise NN cord-010398-5wot7tix 234 24 [ [ -LRB- cord-010398-5wot7tix 234 25 66 66 CD cord-010398-5wot7tix 234 26 , , , cord-010398-5wot7tix 234 27 132 132 CD cord-010398-5wot7tix 234 28 ] ] -RRB- cord-010398-5wot7tix 234 29 . . . cord-010398-5wot7tix 235 1 This this DT cord-010398-5wot7tix 235 2 theoretical theoretical JJ cord-010398-5wot7tix 235 3 link link NN cord-010398-5wot7tix 235 4 among among IN cord-010398-5wot7tix 235 5 stress stress NN cord-010398-5wot7tix 235 6 , , , cord-010398-5wot7tix 235 7 changes change NNS cord-010398-5wot7tix 235 8 in in IN cord-010398-5wot7tix 235 9 stress stress NN cord-010398-5wot7tix 235 10 axis axis NN cord-010398-5wot7tix 235 11 activity activity NN cord-010398-5wot7tix 235 12 , , , cord-010398-5wot7tix 235 13 and and CC cord-010398-5wot7tix 235 14 subsequent subsequent JJ cord-010398-5wot7tix 235 15 susceptibility susceptibility NN cord-010398-5wot7tix 235 16 to to TO cord-010398-5wot7tix 235 17 develop develop VB cord-010398-5wot7tix 235 18 fatigue fatigue NN cord-010398-5wot7tix 235 19 or or CC cord-010398-5wot7tix 235 20 other other JJ cord-010398-5wot7tix 235 21 somatic somatic JJ cord-010398-5wot7tix 235 22 symptoms symptom NNS cord-010398-5wot7tix 235 23 or or CC cord-010398-5wot7tix 235 24 syndromes syndrome NNS cord-010398-5wot7tix 235 25 is be VBZ cord-010398-5wot7tix 235 26 also also RB cord-010398-5wot7tix 235 27 supported support VBN cord-010398-5wot7tix 235 28 by by IN cord-010398-5wot7tix 235 29 studies study NNS cord-010398-5wot7tix 235 30 demonstrating demonstrate VBG cord-010398-5wot7tix 235 31 that that IN cord-010398-5wot7tix 235 32 patients patient NNS cord-010398-5wot7tix 235 33 with with IN cord-010398-5wot7tix 235 34 FM FM NNP cord-010398-5wot7tix 235 35 and and CC cord-010398-5wot7tix 235 36 related relate VBN cord-010398-5wot7tix 235 37 conditions condition NNS cord-010398-5wot7tix 235 38 may may MD cord-010398-5wot7tix 235 39 be be VB cord-010398-5wot7tix 235 40 more more RBR cord-010398-5wot7tix 235 41 likely likely JJ cord-010398-5wot7tix 235 42 than than IN cord-010398-5wot7tix 235 43 nonaffected nonaffecte VBN cord-010398-5wot7tix 235 44 patients patient NNS cord-010398-5wot7tix 235 45 to to TO cord-010398-5wot7tix 235 46 have have VB cord-010398-5wot7tix 235 47 experienced experience VBN cord-010398-5wot7tix 235 48 physical physical JJ cord-010398-5wot7tix 235 49 or or CC cord-010398-5wot7tix 235 50 sexual sexual JJ cord-010398-5wot7tix 235 51 abuse abuse NN cord-010398-5wot7tix 235 52 in in IN cord-010398-5wot7tix 235 53 childhood childhood NN cord-010398-5wot7tix 235 54 [ [ -LRB- cord-010398-5wot7tix 235 55 133 133 CD cord-010398-5wot7tix 235 56 ] ] -RRB- cord-010398-5wot7tix 235 57 [ [ -LRB- cord-010398-5wot7tix 235 58 134 134 CD cord-010398-5wot7tix 235 59 ] ] -RRB- cord-010398-5wot7tix 235 60 [ [ -LRB- cord-010398-5wot7tix 235 61 135 135 CD cord-010398-5wot7tix 235 62 ] ] -RRB- cord-010398-5wot7tix 235 63 [ [ -LRB- cord-010398-5wot7tix 235 64 136 136 CD cord-010398-5wot7tix 235 65 ] ] -RRB- cord-010398-5wot7tix 235 66 . . . cord-010398-5wot7tix 236 1 This this DT cord-010398-5wot7tix 236 2 appears appear VBZ cord-010398-5wot7tix 236 3 to to TO cord-010398-5wot7tix 236 4 profoundly profoundly RB cord-010398-5wot7tix 236 5 influence influence VB cord-010398-5wot7tix 236 6 HPA HPA NNP cord-010398-5wot7tix 236 7 function function NN cord-010398-5wot7tix 236 8 in in IN cord-010398-5wot7tix 236 9 CFS CFS NNP cord-010398-5wot7tix 236 10 , , , cord-010398-5wot7tix 236 11 and and CC cord-010398-5wot7tix 236 12 recent recent JJ cord-010398-5wot7tix 236 13 studies study NNS cord-010398-5wot7tix 236 14 in in IN cord-010398-5wot7tix 236 15 CFS CFS NNP cord-010398-5wot7tix 236 16 have have VBP cord-010398-5wot7tix 236 17 established establish VBN cord-010398-5wot7tix 236 18 that that IN cord-010398-5wot7tix 236 19 early early JJ cord-010398-5wot7tix 236 20 life life NN cord-010398-5wot7tix 236 21 stress stress NN cord-010398-5wot7tix 236 22 is be VBZ cord-010398-5wot7tix 236 23 similarly similarly RB cord-010398-5wot7tix 236 24 a a DT cord-010398-5wot7tix 236 25 major major JJ cord-010398-5wot7tix 236 26 determinant determinant NN cord-010398-5wot7tix 236 27 of of IN cord-010398-5wot7tix 236 28 the the DT cord-010398-5wot7tix 236 29 abnormal abnormal JJ cord-010398-5wot7tix 236 30 HPA HPA NNP cord-010398-5wot7tix 236 31 findings finding NNS cord-010398-5wot7tix 236 32 in in IN cord-010398-5wot7tix 236 33 a a DT cord-010398-5wot7tix 236 34 group group NN cord-010398-5wot7tix 236 35 of of IN cord-010398-5wot7tix 236 36 CFS CFS NNP cord-010398-5wot7tix 236 37 patients patient NNS cord-010398-5wot7tix 236 38 versus versus IN cord-010398-5wot7tix 236 39 controls control NNS cord-010398-5wot7tix 236 40 . . . cord-010398-5wot7tix 237 1 This this DT cord-010398-5wot7tix 237 2 pattern pattern NN cord-010398-5wot7tix 237 3 of of IN cord-010398-5wot7tix 237 4 HPA HPA NNP cord-010398-5wot7tix 237 5 hyporesponsiveness hyporesponsiveness NN cord-010398-5wot7tix 237 6 was be VBD cord-010398-5wot7tix 237 7 predictive predictive JJ cord-010398-5wot7tix 237 8 of of IN cord-010398-5wot7tix 237 9 a a DT cord-010398-5wot7tix 237 10 lack lack NN cord-010398-5wot7tix 237 11 of of IN cord-010398-5wot7tix 237 12 response response NN cord-010398-5wot7tix 237 13 to to IN cord-010398-5wot7tix 237 14 CBT CBT NNP cord-010398-5wot7tix 237 15 , , , cord-010398-5wot7tix 237 16 demonstrating demonstrate VBG cord-010398-5wot7tix 237 17 the the DT cord-010398-5wot7tix 237 18 importance importance NN cord-010398-5wot7tix 237 19 of of IN cord-010398-5wot7tix 237 20 identifying identify VBG cord-010398-5wot7tix 237 21 subsets subset NNS cord-010398-5wot7tix 237 22 of of IN cord-010398-5wot7tix 237 23 patients patient NNS cord-010398-5wot7tix 237 24 before before IN cord-010398-5wot7tix 237 25 treatment treatment NN cord-010398-5wot7tix 237 26 [ [ -LRB- cord-010398-5wot7tix 237 27 128 128 CD cord-010398-5wot7tix 237 28 , , , cord-010398-5wot7tix 237 29 137 137 CD cord-010398-5wot7tix 237 30 ] ] -RRB- cord-010398-5wot7tix 237 31 . . . cord-010398-5wot7tix 238 1 Heart heart NN cord-010398-5wot7tix 238 2 rate rate NN cord-010398-5wot7tix 238 3 variability variability NN cord-010398-5wot7tix 238 4 at at IN cord-010398-5wot7tix 238 5 baseline baseline NN cord-010398-5wot7tix 238 6 , , , cord-010398-5wot7tix 238 7 and and CC cord-010398-5wot7tix 238 8 with with IN cord-010398-5wot7tix 238 9 tilt tilt NN cord-010398-5wot7tix 238 10 table table NN cord-010398-5wot7tix 238 11 testing testing NN cord-010398-5wot7tix 238 12 , , , cord-010398-5wot7tix 238 13 has have VBZ cord-010398-5wot7tix 238 14 been be VBN cord-010398-5wot7tix 238 15 evaluated evaluate VBN cord-010398-5wot7tix 238 16 in in IN cord-010398-5wot7tix 238 17 patients patient NNS cord-010398-5wot7tix 238 18 with with IN cord-010398-5wot7tix 238 19 CFS CFS NNP cord-010398-5wot7tix 238 20 and and CC cord-010398-5wot7tix 238 21 FM FM NNP cord-010398-5wot7tix 238 22 as as IN cord-010398-5wot7tix 238 23 a a DT cord-010398-5wot7tix 238 24 surrogate surrogate JJ cord-010398-5wot7tix 238 25 measure measure NN cord-010398-5wot7tix 238 26 of of IN cord-010398-5wot7tix 238 27 autonomic autonomic JJ cord-010398-5wot7tix 238 28 function function NN cord-010398-5wot7tix 238 29 . . . cord-010398-5wot7tix 239 1 Findings finding NNS cord-010398-5wot7tix 239 2 have have VBP cord-010398-5wot7tix 239 3 been be VBN cord-010398-5wot7tix 239 4 somewhat somewhat RB cord-010398-5wot7tix 239 5 inconsistent inconsistent JJ cord-010398-5wot7tix 239 6 , , , cord-010398-5wot7tix 239 7 especially especially RB cord-010398-5wot7tix 239 8 with with IN cord-010398-5wot7tix 239 9 tilt tilt NN cord-010398-5wot7tix 239 10 table table NN cord-010398-5wot7tix 239 11 testing testing NN cord-010398-5wot7tix 239 12 [ [ -LRB- cord-010398-5wot7tix 239 13 138 138 CD cord-010398-5wot7tix 239 14 ] ] -RRB- cord-010398-5wot7tix 239 15 . . . cord-010398-5wot7tix 240 1 Some some DT cord-010398-5wot7tix 240 2 of of IN cord-010398-5wot7tix 240 3 these these DT cord-010398-5wot7tix 240 4 findings finding NNS cord-010398-5wot7tix 240 5 may may MD cord-010398-5wot7tix 240 6 be be VB cord-010398-5wot7tix 240 7 indicative indicative JJ cord-010398-5wot7tix 240 8 of of IN cord-010398-5wot7tix 240 9 uncovering uncover VBG cord-010398-5wot7tix 240 10 a a DT cord-010398-5wot7tix 240 11 diathesis diathesis NN cord-010398-5wot7tix 240 12 to to TO cord-010398-5wot7tix 240 13 stress stress NN cord-010398-5wot7tix 240 14 , , , cord-010398-5wot7tix 240 15 or or CC cord-010398-5wot7tix 240 16 a a DT cord-010398-5wot7tix 240 17 response response NN cord-010398-5wot7tix 240 18 to to IN cord-010398-5wot7tix 240 19 deconditioning deconditione VBG cord-010398-5wot7tix 240 20 . . . cord-010398-5wot7tix 241 1 For for IN cord-010398-5wot7tix 241 2 example example NN cord-010398-5wot7tix 241 3 , , , cord-010398-5wot7tix 241 4 several several JJ cord-010398-5wot7tix 241 5 experimental experimental JJ cord-010398-5wot7tix 241 6 studies study NNS cord-010398-5wot7tix 241 7 have have VBP cord-010398-5wot7tix 241 8 shown show VBN cord-010398-5wot7tix 241 9 that that IN cord-010398-5wot7tix 241 10 alterations alteration NNS cord-010398-5wot7tix 241 11 in in IN cord-010398-5wot7tix 241 12 heart heart NN cord-010398-5wot7tix 241 13 rate rate NN cord-010398-5wot7tix 241 14 variability variability NN cord-010398-5wot7tix 241 15 similar similar JJ cord-010398-5wot7tix 241 16 to to IN cord-010398-5wot7tix 241 17 those those DT cord-010398-5wot7tix 241 18 in in IN cord-010398-5wot7tix 241 19 CFS CFS NNP cord-010398-5wot7tix 241 20 or or CC cord-010398-5wot7tix 241 21 FM FM NNP cord-010398-5wot7tix 241 22 populations population NNS cord-010398-5wot7tix 241 23 may may MD cord-010398-5wot7tix 241 24 actually actually RB cord-010398-5wot7tix 241 25 represent represent VB cord-010398-5wot7tix 241 26 a a DT cord-010398-5wot7tix 241 27 diathesis diathesis NN cord-010398-5wot7tix 241 28 as as IN cord-010398-5wot7tix 241 29 a a DT cord-010398-5wot7tix 241 30 marker marker NN cord-010398-5wot7tix 241 31 of of IN cord-010398-5wot7tix 241 32 autonomic autonomic JJ cord-010398-5wot7tix 241 33 tone tone NN cord-010398-5wot7tix 241 34 that that WDT cord-010398-5wot7tix 241 35 places place VBZ cord-010398-5wot7tix 241 36 patients patient NNS cord-010398-5wot7tix 241 37 at at IN cord-010398-5wot7tix 241 38 risk risk NN cord-010398-5wot7tix 241 39 for for IN cord-010398-5wot7tix 241 40 developing develop VBG cord-010398-5wot7tix 241 41 CFS CFS NNP cord-010398-5wot7tix 241 42 , , , cord-010398-5wot7tix 241 43 FM FM NNP cord-010398-5wot7tix 241 44 , , , cord-010398-5wot7tix 241 45 or or CC cord-010398-5wot7tix 241 46 related relate VBN cord-010398-5wot7tix 241 47 illnesses illness NNS cord-010398-5wot7tix 241 48 [ [ -LRB- cord-010398-5wot7tix 241 49 66 66 CD cord-010398-5wot7tix 241 50 , , , cord-010398-5wot7tix 241 51 132 132 CD cord-010398-5wot7tix 241 52 , , , cord-010398-5wot7tix 241 53 139 139 CD cord-010398-5wot7tix 241 54 ] ] -RRB- cord-010398-5wot7tix 241 55 , , , cord-010398-5wot7tix 241 56 possibly possibly RB cord-010398-5wot7tix 241 57 identifying identify VBG cord-010398-5wot7tix 241 58 patients patient NNS cord-010398-5wot7tix 241 59 at at IN cord-010398-5wot7tix 241 60 risk risk NN cord-010398-5wot7tix 241 61 . . . cord-010398-5wot7tix 242 1 Also also RB cord-010398-5wot7tix 242 2 , , , cord-010398-5wot7tix 242 3 a a DT cord-010398-5wot7tix 242 4 recent recent JJ cord-010398-5wot7tix 242 5 study study NN cord-010398-5wot7tix 242 6 showed show VBD cord-010398-5wot7tix 242 7 that that IN cord-010398-5wot7tix 242 8 heart heart NN cord-010398-5wot7tix 242 9 rate rate NN cord-010398-5wot7tix 242 10 variability variability NN cord-010398-5wot7tix 242 11 was be VBD cord-010398-5wot7tix 242 12 normalized normalize VBN cord-010398-5wot7tix 242 13 after after IN cord-010398-5wot7tix 242 14 exercise exercise NN cord-010398-5wot7tix 242 15 therapy therapy NN cord-010398-5wot7tix 242 16 , , , cord-010398-5wot7tix 242 17 suggesting suggest VBG cord-010398-5wot7tix 242 18 that that IN cord-010398-5wot7tix 242 19 some some DT cord-010398-5wot7tix 242 20 of of IN cord-010398-5wot7tix 242 21 these these DT cord-010398-5wot7tix 242 22 findings finding NNS cord-010398-5wot7tix 242 23 may may MD cord-010398-5wot7tix 242 24 be be VB cord-010398-5wot7tix 242 25 an an DT cord-010398-5wot7tix 242 26 epiphenomenon epiphenomenon NN cord-010398-5wot7tix 242 27 caused cause VBN cord-010398-5wot7tix 242 28 in in IN cord-010398-5wot7tix 242 29 part part NN cord-010398-5wot7tix 242 30 by by IN cord-010398-5wot7tix 242 31 deconditioning deconditione VBG cord-010398-5wot7tix 242 32 [ [ -LRB- cord-010398-5wot7tix 242 33 140 140 CD cord-010398-5wot7tix 242 34 , , , cord-010398-5wot7tix 242 35 141 141 CD cord-010398-5wot7tix 242 36 ] ] -RRB- cord-010398-5wot7tix 242 37 . . . cord-010398-5wot7tix 243 1 However however RB cord-010398-5wot7tix 243 2 , , , cord-010398-5wot7tix 243 3 there there EX cord-010398-5wot7tix 243 4 clearly clearly RB cord-010398-5wot7tix 243 5 is be VBZ cord-010398-5wot7tix 243 6 a a DT cord-010398-5wot7tix 243 7 subset subset NN cord-010398-5wot7tix 243 8 of of IN cord-010398-5wot7tix 243 9 patients patient NNS cord-010398-5wot7tix 243 10 with with IN cord-010398-5wot7tix 243 11 prominent prominent JJ cord-010398-5wot7tix 243 12 autonomic autonomic JJ cord-010398-5wot7tix 243 13 dysfunction dysfunction NN cord-010398-5wot7tix 243 14 within within IN cord-010398-5wot7tix 243 15 this this DT cord-010398-5wot7tix 243 16 spectrum spectrum NN cord-010398-5wot7tix 243 17 of of IN cord-010398-5wot7tix 243 18 disorders disorder NNS cord-010398-5wot7tix 243 19 , , , cord-010398-5wot7tix 243 20 and and CC cord-010398-5wot7tix 243 21 the the DT cord-010398-5wot7tix 243 22 authors author NNS cord-010398-5wot7tix 243 23 of of IN cord-010398-5wot7tix 243 24 a a DT cord-010398-5wot7tix 243 25 recent recent JJ cord-010398-5wot7tix 243 26 study study NN cord-010398-5wot7tix 243 27 [ [ -LRB- cord-010398-5wot7tix 243 28 142 142 CD cord-010398-5wot7tix 243 29 ] ] -RRB- cord-010398-5wot7tix 243 30 suggest suggest VBP cord-010398-5wot7tix 243 31 that that IN cord-010398-5wot7tix 243 32 deconditioning deconditione VBG cord-010398-5wot7tix 243 33 plays play VBZ cord-010398-5wot7tix 243 34 a a DT cord-010398-5wot7tix 243 35 role role NN cord-010398-5wot7tix 243 36 , , , cord-010398-5wot7tix 243 37 and and CC cord-010398-5wot7tix 243 38 a a DT cord-010398-5wot7tix 243 39 subset subset NN cord-010398-5wot7tix 243 40 of of IN cord-010398-5wot7tix 243 41 individuals individual NNS cord-010398-5wot7tix 243 42 with with IN cord-010398-5wot7tix 243 43 low low JJ cord-010398-5wot7tix 243 44 cardiac cardiac JJ cord-010398-5wot7tix 243 45 output output NN cord-010398-5wot7tix 243 46 . . . cord-010398-5wot7tix 244 1 Recent recent JJ cord-010398-5wot7tix 244 2 studies study NNS cord-010398-5wot7tix 244 3 have have VBP cord-010398-5wot7tix 244 4 pointed point VBN cord-010398-5wot7tix 244 5 out out RP cord-010398-5wot7tix 244 6 that that IN cord-010398-5wot7tix 244 7 some some DT cord-010398-5wot7tix 244 8 of of IN cord-010398-5wot7tix 244 9 this this DT cord-010398-5wot7tix 244 10 autonomic autonomic JJ cord-010398-5wot7tix 244 11 dysfunction dysfunction NN cord-010398-5wot7tix 244 12 may may MD cord-010398-5wot7tix 244 13 be be VB cord-010398-5wot7tix 244 14 due due JJ cord-010398-5wot7tix 244 15 to to IN cord-010398-5wot7tix 244 16 deconditioning deconditioning NN cord-010398-5wot7tix 244 17 , , , cord-010398-5wot7tix 244 18 and and CC cord-010398-5wot7tix 244 19 that that IN cord-010398-5wot7tix 244 20 in in IN cord-010398-5wot7tix 244 21 some some DT cord-010398-5wot7tix 244 22 individuals individual NNS cord-010398-5wot7tix 244 23 with with IN cord-010398-5wot7tix 244 24 CFS CFS NNP cord-010398-5wot7tix 244 25 this this DT cord-010398-5wot7tix 244 26 may may MD cord-010398-5wot7tix 244 27 be be VB cord-010398-5wot7tix 244 28 severe severe JJ cord-010398-5wot7tix 244 29 enough enough RB cord-010398-5wot7tix 244 30 to to TO cord-010398-5wot7tix 244 31 lead lead VB cord-010398-5wot7tix 244 32 to to TO cord-010398-5wot7tix 244 33 lead lead VB cord-010398-5wot7tix 244 34 to to IN cord-010398-5wot7tix 244 35 low low JJ cord-010398-5wot7tix 244 36 cardiac cardiac JJ cord-010398-5wot7tix 244 37 output output NN cord-010398-5wot7tix 244 38 . . . cord-010398-5wot7tix 245 1 Peripheral peripheral JJ cord-010398-5wot7tix 245 2 fatigue fatigue NN cord-010398-5wot7tix 245 3 is be VBZ cord-010398-5wot7tix 245 4 likely likely JJ cord-010398-5wot7tix 245 5 to to TO cord-010398-5wot7tix 245 6 contribute contribute VB cord-010398-5wot7tix 245 7 to to IN cord-010398-5wot7tix 245 8 the the DT cord-010398-5wot7tix 245 9 fatigue fatigue NN cord-010398-5wot7tix 245 10 picture picture NN cord-010398-5wot7tix 245 11 in in IN cord-010398-5wot7tix 245 12 these these DT cord-010398-5wot7tix 245 13 patients patient NNS cord-010398-5wot7tix 245 14 with with IN cord-010398-5wot7tix 245 15 CFS CFS NNP cord-010398-5wot7tix 245 16 and and CC cord-010398-5wot7tix 245 17 FM FM NNP cord-010398-5wot7tix 245 18 . . . cord-010398-5wot7tix 246 1 It -PRON- PRP cord-010398-5wot7tix 246 2 is be VBZ cord-010398-5wot7tix 246 3 likely likely JJ cord-010398-5wot7tix 246 4 that that IN cord-010398-5wot7tix 246 5 these these DT cord-010398-5wot7tix 246 6 neurobiological neurobiological JJ cord-010398-5wot7tix 246 7 alterations alteration NNS cord-010398-5wot7tix 246 8 are be VBP cord-010398-5wot7tix 246 9 shared share VBN cord-010398-5wot7tix 246 10 with with IN cord-010398-5wot7tix 246 11 other other JJ cord-010398-5wot7tix 246 12 syndromes syndrome NNS cord-010398-5wot7tix 246 13 known know VBN cord-010398-5wot7tix 246 14 to to TO cord-010398-5wot7tix 246 15 be be VB cord-010398-5wot7tix 246 16 associated associate VBN cord-010398-5wot7tix 246 17 with with IN cord-010398-5wot7tix 246 18 HPA HPA NNP cord-010398-5wot7tix 246 19 and/or and/or CC cord-010398-5wot7tix 246 20 autonomic autonomic JJ cord-010398-5wot7tix 246 21 function function NN cord-010398-5wot7tix 246 22 such such JJ cord-010398-5wot7tix 246 23 as as IN cord-010398-5wot7tix 246 24 depression depression NN cord-010398-5wot7tix 246 25 or or CC cord-010398-5wot7tix 246 26 posttraumatic posttraumatic JJ cord-010398-5wot7tix 246 27 stress stress NN cord-010398-5wot7tix 246 28 disorder disorder NN cord-010398-5wot7tix 246 29 . . . cord-010398-5wot7tix 247 1 A a DT cord-010398-5wot7tix 247 2 model model NN cord-010398-5wot7tix 247 3 of of IN cord-010398-5wot7tix 247 4 susceptibility susceptibility NN cord-010398-5wot7tix 247 5 and and CC cord-010398-5wot7tix 247 6 developmental developmental JJ cord-010398-5wot7tix 247 7 aspects aspect NNS cord-010398-5wot7tix 247 8 of of IN cord-010398-5wot7tix 247 9 these these DT cord-010398-5wot7tix 247 10 disorders disorder NNS cord-010398-5wot7tix 247 11 that that WDT cord-010398-5wot7tix 247 12 takes take VBZ cord-010398-5wot7tix 247 13 into into IN cord-010398-5wot7tix 247 14 account account NN cord-010398-5wot7tix 247 15 both both CC cord-010398-5wot7tix 247 16 genetics genetic NNS cord-010398-5wot7tix 247 17 and and CC cord-010398-5wot7tix 247 18 personality personality NN cord-010398-5wot7tix 247 19 as as IN cord-010398-5wot7tix 247 20 risk risk NN cord-010398-5wot7tix 247 21 factors factor NNS cord-010398-5wot7tix 247 22 is be VBZ cord-010398-5wot7tix 247 23 illustrated illustrate VBN cord-010398-5wot7tix 247 24 in in IN cord-010398-5wot7tix 247 25 Figure Figure NNP cord-010398-5wot7tix 247 26 _SP cord-010398-5wot7tix 247 27 3 3 CD cord-010398-5wot7tix 247 28 . . . cord-010398-5wot7tix 248 1 This this DT cord-010398-5wot7tix 248 2 recognizes recognize VBZ cord-010398-5wot7tix 248 3 the the DT cord-010398-5wot7tix 248 4 critical critical JJ cord-010398-5wot7tix 248 5 importance importance NN cord-010398-5wot7tix 248 6 of of IN cord-010398-5wot7tix 248 7 stressors stressor NNS cord-010398-5wot7tix 248 8 in in IN cord-010398-5wot7tix 248 9 resetting reset VBG cord-010398-5wot7tix 248 10 stress stress NN cord-010398-5wot7tix 248 11 response response NN cord-010398-5wot7tix 248 12 systems system NNS cord-010398-5wot7tix 248 13 , , , cord-010398-5wot7tix 248 14 as as RB cord-010398-5wot7tix 248 15 well well RB cord-010398-5wot7tix 248 16 as as IN cord-010398-5wot7tix 248 17 other other JJ cord-010398-5wot7tix 248 18 factors factor NNS cord-010398-5wot7tix 248 19 , , , cord-010398-5wot7tix 248 20 including include VBG cord-010398-5wot7tix 248 21 ( ( -LRB- cord-010398-5wot7tix 248 22 1 1 LS cord-010398-5wot7tix 248 23 ) ) -RRB- cord-010398-5wot7tix 248 24 the the DT cord-010398-5wot7tix 248 25 role role NN cord-010398-5wot7tix 248 26 of of IN cord-010398-5wot7tix 248 27 behavioral behavioral JJ cord-010398-5wot7tix 248 28 adaptations adaptation NNS cord-010398-5wot7tix 248 29 to to IN cord-010398-5wot7tix 248 30 these these DT cord-010398-5wot7tix 248 31 stressors stressor NNS cord-010398-5wot7tix 248 32 such such JJ cord-010398-5wot7tix 248 33 as as IN cord-010398-5wot7tix 248 34 cessation cessation NN cord-010398-5wot7tix 248 35 of of IN cord-010398-5wot7tix 248 36 routine routine JJ cord-010398-5wot7tix 248 37 exercise exercise NN cord-010398-5wot7tix 248 38 and and CC cord-010398-5wot7tix 248 39 ( ( -LRB- cord-010398-5wot7tix 248 40 2 2 LS cord-010398-5wot7tix 248 41 ) ) -RRB- cord-010398-5wot7tix 248 42 whether whether IN cord-010398-5wot7tix 248 43 an an DT cord-010398-5wot7tix 248 44 individual individual NN cord-010398-5wot7tix 248 45 is be VBZ cord-010398-5wot7tix 248 46 in in IN cord-010398-5wot7tix 248 47 an an DT cord-010398-5wot7tix 248 48 environment environment NN cord-010398-5wot7tix 248 49 characterized characterize VBN cord-010398-5wot7tix 248 50 by by IN cord-010398-5wot7tix 248 51 control control NN cord-010398-5wot7tix 248 52 or or CC cord-010398-5wot7tix 248 53 support support NN cord-010398-5wot7tix 248 54 . . . cord-010398-5wot7tix 249 1 Twin twin JJ cord-010398-5wot7tix 249 2 studies study NNS cord-010398-5wot7tix 249 3 have have VBP cord-010398-5wot7tix 249 4 been be VBN cord-010398-5wot7tix 249 5 very very RB cord-010398-5wot7tix 249 6 instructive instructive JJ cord-010398-5wot7tix 249 7 in in IN cord-010398-5wot7tix 249 8 determining determine VBG cord-010398-5wot7tix 249 9 key key JJ cord-010398-5wot7tix 249 10 clinical clinical JJ cord-010398-5wot7tix 249 11 features feature NNS cord-010398-5wot7tix 249 12 as as RB cord-010398-5wot7tix 249 13 well well RB cord-010398-5wot7tix 249 14 as as IN cord-010398-5wot7tix 249 15 estimations estimation NNS cord-010398-5wot7tix 249 16 of of IN cord-010398-5wot7tix 249 17 the the DT cord-010398-5wot7tix 249 18 roles role NNS cord-010398-5wot7tix 249 19 of of IN cord-010398-5wot7tix 249 20 genetics genetic NNS cord-010398-5wot7tix 249 21 versus versus IN cord-010398-5wot7tix 249 22 environmental environmental JJ cord-010398-5wot7tix 249 23 factors factor NNS cord-010398-5wot7tix 249 24 . . . cord-010398-5wot7tix 250 1 Kato Kato NNP cord-010398-5wot7tix 250 2 and and CC cord-010398-5wot7tix 250 3 colleagues colleague NNS cord-010398-5wot7tix 250 4 [ [ -LRB- cord-010398-5wot7tix 250 5 39 39 CD cord-010398-5wot7tix 250 6 , , , cord-010398-5wot7tix 250 7 143 143 CD cord-010398-5wot7tix 250 8 , , , cord-010398-5wot7tix 250 9 144 144 CD cord-010398-5wot7tix 250 10 ] ] -RRB- cord-010398-5wot7tix 250 11 have have VBP cord-010398-5wot7tix 250 12 performed perform VBN cord-010398-5wot7tix 250 13 a a DT cord-010398-5wot7tix 250 14 series series NN cord-010398-5wot7tix 250 15 of of IN cord-010398-5wot7tix 250 16 studies study NNS cord-010398-5wot7tix 250 17 by by IN cord-010398-5wot7tix 250 18 using use VBG cord-010398-5wot7tix 250 19 a a DT cord-010398-5wot7tix 250 20 very very RB cord-010398-5wot7tix 250 21 large large JJ cord-010398-5wot7tix 250 22 Swedish swedish JJ cord-010398-5wot7tix 250 23 twin twin NN cord-010398-5wot7tix 250 24 registry registry NN cord-010398-5wot7tix 250 25 and and CC cord-010398-5wot7tix 250 26 have have VBP cord-010398-5wot7tix 250 27 determined determine VBN cord-010398-5wot7tix 250 28 that that IN cord-010398-5wot7tix 250 29 CFS CFS NNP cord-010398-5wot7tix 250 30 , , , cord-010398-5wot7tix 250 31 FM FM NNP cord-010398-5wot7tix 250 32 , , , cord-010398-5wot7tix 250 33 IBS IBS NNP cord-010398-5wot7tix 250 34 , , , cord-010398-5wot7tix 250 35 and and CC cord-010398-5wot7tix 250 36 headache headache NN cord-010398-5wot7tix 250 37 share share NN cord-010398-5wot7tix 250 38 key key JJ cord-010398-5wot7tix 250 39 symptoms symptom NNS cord-010398-5wot7tix 250 40 of of IN cord-010398-5wot7tix 250 41 fatigue fatigue NN cord-010398-5wot7tix 250 42 , , , cord-010398-5wot7tix 250 43 multifocal multifocal JJ cord-010398-5wot7tix 250 44 pain pain NN cord-010398-5wot7tix 250 45 , , , cord-010398-5wot7tix 250 46 insomnia insomnia NN cord-010398-5wot7tix 250 47 , , , cord-010398-5wot7tix 250 48 and and CC cord-010398-5wot7tix 250 49 memory memory NN cord-010398-5wot7tix 250 50 difficulties difficulty NNS cord-010398-5wot7tix 250 51 and and CC cord-010398-5wot7tix 250 52 that that IN cord-010398-5wot7tix 250 53 they -PRON- PRP cord-010398-5wot7tix 250 54 can can MD cord-010398-5wot7tix 250 55 be be VB cord-010398-5wot7tix 250 56 clearly clearly RB cord-010398-5wot7tix 250 57 distinguishable distinguishable JJ cord-010398-5wot7tix 250 58 from from IN cord-010398-5wot7tix 250 59 depression depression NN cord-010398-5wot7tix 250 60 and and CC cord-010398-5wot7tix 250 61 anxiety anxiety NN cord-010398-5wot7tix 250 62 . . . cord-010398-5wot7tix 251 1 In in IN cord-010398-5wot7tix 251 2 aggregate aggregate NN cord-010398-5wot7tix 251 3 , , , cord-010398-5wot7tix 251 4 these these DT cord-010398-5wot7tix 251 5 studies study NNS cord-010398-5wot7tix 251 6 suggest suggest VBP cord-010398-5wot7tix 251 7 that that IN cord-010398-5wot7tix 251 8 approximately approximately RB cord-010398-5wot7tix 251 9 half half PDT cord-010398-5wot7tix 251 10 the the DT cord-010398-5wot7tix 251 11 risk risk NN cord-010398-5wot7tix 251 12 of of IN cord-010398-5wot7tix 251 13 developing develop VBG cord-010398-5wot7tix 251 14 these these DT cord-010398-5wot7tix 251 15 illnesses illness NNS cord-010398-5wot7tix 251 16 is be VBZ cord-010398-5wot7tix 251 17 genetic genetic JJ cord-010398-5wot7tix 251 18 and and CC cord-010398-5wot7tix 251 19 the the DT cord-010398-5wot7tix 251 20 other other JJ cord-010398-5wot7tix 251 21 half half NN cord-010398-5wot7tix 251 22 environmental environmental JJ cord-010398-5wot7tix 251 23 . . . cord-010398-5wot7tix 252 1 A a DT cord-010398-5wot7tix 252 2 series series NN cord-010398-5wot7tix 252 3 of of IN cord-010398-5wot7tix 252 4 elegant elegant JJ cord-010398-5wot7tix 252 5 twin twin JJ cord-010398-5wot7tix 252 6 studies study NNS cord-010398-5wot7tix 252 7 performed perform VBN cord-010398-5wot7tix 252 8 by by IN cord-010398-5wot7tix 252 9 Buchwald Buchwald NNP cord-010398-5wot7tix 252 10 and and CC cord-010398-5wot7tix 252 11 colleagues colleague NNS cord-010398-5wot7tix 252 12 [ [ -LRB- cord-010398-5wot7tix 252 13 18 18 CD cord-010398-5wot7tix 252 14 , , , cord-010398-5wot7tix 252 15 [ [ -LRB- cord-010398-5wot7tix 252 16 145 145 CD cord-010398-5wot7tix 252 17 ] ] -RRB- cord-010398-5wot7tix 252 18 [ [ -LRB- cord-010398-5wot7tix 252 19 146 146 CD cord-010398-5wot7tix 252 20 ] ] -RRB- cord-010398-5wot7tix 252 21 [ [ -LRB- cord-010398-5wot7tix 252 22 147 147 CD cord-010398-5wot7tix 252 23 ] ] -RRB- cord-010398-5wot7tix 252 24 [ [ -LRB- cord-010398-5wot7tix 252 25 148 148 CD cord-010398-5wot7tix 252 26 ] ] -RRB- cord-010398-5wot7tix 252 27 [ [ -LRB- cord-010398-5wot7tix 252 28 149 149 CD cord-010398-5wot7tix 252 29 ] ] -RRB- cord-010398-5wot7tix 252 30 with with IN cord-010398-5wot7tix 252 31 identical identical JJ cord-010398-5wot7tix 252 32 twins twin NNS cord-010398-5wot7tix 252 33 discordant discordant JJ cord-010398-5wot7tix 252 34 for for IN cord-010398-5wot7tix 252 35 CFS CFS NNP cord-010398-5wot7tix 252 36 has have VBZ cord-010398-5wot7tix 252 37 generally generally RB cord-010398-5wot7tix 252 38 shown show VBN cord-010398-5wot7tix 252 39 very very RB cord-010398-5wot7tix 252 40 few few JJ cord-010398-5wot7tix 252 41 objective objective JJ cord-010398-5wot7tix 252 42 differences difference NNS cord-010398-5wot7tix 252 43 in in IN cord-010398-5wot7tix 252 44 coping cope VBG cord-010398-5wot7tix 252 45 strategies strategy NNS cord-010398-5wot7tix 252 46 , , , cord-010398-5wot7tix 252 47 sleep sleep NN cord-010398-5wot7tix 252 48 , , , cord-010398-5wot7tix 252 49 and and CC cord-010398-5wot7tix 252 50 a a DT cord-010398-5wot7tix 252 51 number number NN cord-010398-5wot7tix 252 52 of of IN cord-010398-5wot7tix 252 53 other other JJ cord-010398-5wot7tix 252 54 measures measure NNS cord-010398-5wot7tix 252 55 . . . cord-010398-5wot7tix 253 1 They -PRON- PRP cord-010398-5wot7tix 253 2 have have VBP cord-010398-5wot7tix 253 3 suggested suggest VBN cord-010398-5wot7tix 253 4 that that IN cord-010398-5wot7tix 253 5 genetic genetic JJ cord-010398-5wot7tix 253 6 factors factor NNS cord-010398-5wot7tix 253 7 may may MD cord-010398-5wot7tix 253 8 be be VB cord-010398-5wot7tix 253 9 playing play VBG cord-010398-5wot7tix 253 10 a a DT cord-010398-5wot7tix 253 11 more more RBR cord-010398-5wot7tix 253 12 significant significant JJ cord-010398-5wot7tix 253 13 role role NN cord-010398-5wot7tix 253 14 in in IN cord-010398-5wot7tix 253 15 male male NN cord-010398-5wot7tix 253 16 than than IN cord-010398-5wot7tix 253 17 female female JJ cord-010398-5wot7tix 253 18 patients patient NNS cord-010398-5wot7tix 253 19 with with IN cord-010398-5wot7tix 253 20 these these DT cord-010398-5wot7tix 253 21 illnesses illness NNS cord-010398-5wot7tix 253 22 , , , cord-010398-5wot7tix 253 23 and and CC cord-010398-5wot7tix 253 24 the the DT cord-010398-5wot7tix 253 25 authors author NNS cord-010398-5wot7tix 253 26 suggest suggest VBP cord-010398-5wot7tix 253 27 that that IN cord-010398-5wot7tix 253 28 perceptual perceptual JJ cord-010398-5wot7tix 253 29 abnormalities abnormality NNS cord-010398-5wot7tix 253 30 in in IN cord-010398-5wot7tix 253 31 sensory sensory JJ cord-010398-5wot7tix 253 32 symptom symptom NN cord-010398-5wot7tix 253 33 expression expression NN cord-010398-5wot7tix 253 34 may may MD cord-010398-5wot7tix 253 35 represent represent VB cord-010398-5wot7tix 253 36 the the DT cord-010398-5wot7tix 253 37 biggest big JJS cord-010398-5wot7tix 253 38 difference difference NN cord-010398-5wot7tix 253 39 between between IN cord-010398-5wot7tix 253 40 affected affected JJ cord-010398-5wot7tix 253 41 and and CC cord-010398-5wot7tix 253 42 nonaffected nonaffecte VBN cord-010398-5wot7tix 253 43 twins twin NNS cord-010398-5wot7tix 253 44 . . . cord-010398-5wot7tix 254 1 There there EX cord-010398-5wot7tix 254 2 have have VBP cord-010398-5wot7tix 254 3 been be VBN cord-010398-5wot7tix 254 4 very very RB cord-010398-5wot7tix 254 5 few few JJ cord-010398-5wot7tix 254 6 randomized randomize VBN cord-010398-5wot7tix 254 7 controlled control VBN cord-010398-5wot7tix 254 8 trials trial NNS cord-010398-5wot7tix 254 9 of of IN cord-010398-5wot7tix 254 10 drugs drug NNS cord-010398-5wot7tix 254 11 for for IN cord-010398-5wot7tix 254 12 CFS CFS NNP cord-010398-5wot7tix 254 13 , , , cord-010398-5wot7tix 254 14 but but CC cord-010398-5wot7tix 254 15 several several JJ cord-010398-5wot7tix 254 16 drug drug NN cord-010398-5wot7tix 254 17 and and CC cord-010398-5wot7tix 254 18 nondrug nondrug NNP cord-010398-5wot7tix 254 19 therapies therapy NNS cord-010398-5wot7tix 254 20 have have VBP cord-010398-5wot7tix 254 21 been be VBN cord-010398-5wot7tix 254 22 shown show VBN cord-010398-5wot7tix 254 23 to to TO cord-010398-5wot7tix 254 24 be be VB cord-010398-5wot7tix 254 25 effective effective JJ cord-010398-5wot7tix 254 26 for for IN cord-010398-5wot7tix 254 27 nearly nearly RB cord-010398-5wot7tix 254 28 any any DT cord-010398-5wot7tix 254 29 of of IN cord-010398-5wot7tix 254 30 the the DT cord-010398-5wot7tix 254 31 functional functional JJ cord-010398-5wot7tix 254 32 somatic somatic JJ cord-010398-5wot7tix 254 33 or or CC cord-010398-5wot7tix 254 34 central central JJ cord-010398-5wot7tix 254 35 sensitivity sensitivity NN cord-010398-5wot7tix 254 36 disorders disorder NNS cord-010398-5wot7tix 254 37 , , , cord-010398-5wot7tix 254 38 further further RB cord-010398-5wot7tix 254 39 reinforcing reinforce VBG cord-010398-5wot7tix 254 40 that that IN cord-010398-5wot7tix 254 41 this this DT cord-010398-5wot7tix 254 42 may may MD cord-010398-5wot7tix 254 43 well well RB cord-010398-5wot7tix 254 44 be be VB cord-010398-5wot7tix 254 45 a a DT cord-010398-5wot7tix 254 46 large large JJ cord-010398-5wot7tix 254 47 overlapping overlap VBG cord-010398-5wot7tix 254 48 disorder disorder NN cord-010398-5wot7tix 254 49 rather rather RB cord-010398-5wot7tix 254 50 than than IN cord-010398-5wot7tix 254 51 several several JJ cord-010398-5wot7tix 254 52 separate separate JJ cord-010398-5wot7tix 254 53 ones one NNS cord-010398-5wot7tix 254 54 . . . cord-010398-5wot7tix 255 1 Among among IN cord-010398-5wot7tix 255 2 classes class NNS cord-010398-5wot7tix 255 3 of of IN cord-010398-5wot7tix 255 4 drugs drug NNS cord-010398-5wot7tix 255 5 , , , cord-010398-5wot7tix 255 6 substantial substantial JJ cord-010398-5wot7tix 255 7 data datum NNS cord-010398-5wot7tix 255 8 suggest suggest VBP cord-010398-5wot7tix 255 9 that that IN cord-010398-5wot7tix 255 10 tricyclic tricyclic NN cord-010398-5wot7tix 255 11 compounds compound NNS cord-010398-5wot7tix 255 12 are be VBP cord-010398-5wot7tix 255 13 effective effective JJ cord-010398-5wot7tix 255 14 for for IN cord-010398-5wot7tix 255 15 treating treat VBG cord-010398-5wot7tix 255 16 most most JJS cord-010398-5wot7tix 255 17 of of IN cord-010398-5wot7tix 255 18 the the DT cord-010398-5wot7tix 255 19 conditions condition NNS cord-010398-5wot7tix 255 20 noted note VBD cord-010398-5wot7tix 255 21 [ [ -LRB- cord-010398-5wot7tix 255 22 150 150 CD cord-010398-5wot7tix 255 23 ] ] -RRB- cord-010398-5wot7tix 256 1 [ [ -LRB- cord-010398-5wot7tix 256 2 151 151 CD cord-010398-5wot7tix 256 3 ] ] -RRB- cord-010398-5wot7tix 256 4 [ [ -LRB- cord-010398-5wot7tix 256 5 152 152 CD cord-010398-5wot7tix 256 6 ] ] -RRB- cord-010398-5wot7tix 256 7 . . . cord-010398-5wot7tix 257 1 Newer new JJR cord-010398-5wot7tix 257 2 serotonin serotonin NN cord-010398-5wot7tix 257 3 - - HYPH cord-010398-5wot7tix 257 4 norepinephrine norepinephrine NN cord-010398-5wot7tix 257 5 reuptake reuptake NN cord-010398-5wot7tix 257 6 inhibitors inhibitor NNS cord-010398-5wot7tix 257 7 such such JJ cord-010398-5wot7tix 257 8 as as IN cord-010398-5wot7tix 257 9 duloxetine duloxetine NNP cord-010398-5wot7tix 257 10 and and CC cord-010398-5wot7tix 257 11 tramadol tramadol NN cord-010398-5wot7tix 257 12 have have VBP cord-010398-5wot7tix 257 13 similarly similarly RB cord-010398-5wot7tix 257 14 been be VBN cord-010398-5wot7tix 257 15 shown show VBN cord-010398-5wot7tix 257 16 to to TO cord-010398-5wot7tix 257 17 be be VB cord-010398-5wot7tix 257 18 effective effective JJ cord-010398-5wot7tix 257 19 across across IN cord-010398-5wot7tix 257 20 a a DT cord-010398-5wot7tix 257 21 broad broad JJ cord-010398-5wot7tix 257 22 range range NN cord-010398-5wot7tix 257 23 of of IN cord-010398-5wot7tix 257 24 these these DT cord-010398-5wot7tix 257 25 conditions condition NNS cord-010398-5wot7tix 257 26 [ [ -LRB- cord-010398-5wot7tix 257 27 153 153 CD cord-010398-5wot7tix 257 28 ] ] -RRB- cord-010398-5wot7tix 257 29 , , , cord-010398-5wot7tix 257 30 and and CC cord-010398-5wot7tix 257 31 interestingly interestingly RB cord-010398-5wot7tix 257 32 duloxetine duloxetine NNP cord-010398-5wot7tix 257 33 had have VBD cord-010398-5wot7tix 257 34 much much RB cord-010398-5wot7tix 257 35 earlier early RBR cord-010398-5wot7tix 257 36 been be VBN cord-010398-5wot7tix 257 37 shown show VBN cord-010398-5wot7tix 257 38 to to TO cord-010398-5wot7tix 257 39 be be VB cord-010398-5wot7tix 257 40 helpful helpful JJ cord-010398-5wot7tix 257 41 in in IN cord-010398-5wot7tix 257 42 treating treat VBG cord-010398-5wot7tix 257 43 the the DT cord-010398-5wot7tix 257 44 pain pain NN cord-010398-5wot7tix 257 45 associated associate VBN cord-010398-5wot7tix 257 46 with with IN cord-010398-5wot7tix 257 47 depression depression NN cord-010398-5wot7tix 257 48 , , , cord-010398-5wot7tix 257 49 which which WDT cord-010398-5wot7tix 257 50 is be VBZ cord-010398-5wot7tix 257 51 not not RB cord-010398-5wot7tix 257 52 surprising surprising JJ cord-010398-5wot7tix 257 53 . . . cord-010398-5wot7tix 258 1 The the DT cord-010398-5wot7tix 258 2 alpha-2-delta alpha-2-delta NNP cord-010398-5wot7tix 258 3 ligands ligand NNS cord-010398-5wot7tix 258 4 such such JJ cord-010398-5wot7tix 258 5 as as IN cord-010398-5wot7tix 258 6 pregabalin pregabalin NN cord-010398-5wot7tix 258 7 and and CC cord-010398-5wot7tix 258 8 gabapentin gabapentin NNP cord-010398-5wot7tix 258 9 also also RB cord-010398-5wot7tix 258 10 are be VBP cord-010398-5wot7tix 258 11 being be VBG cord-010398-5wot7tix 258 12 shown show VBN cord-010398-5wot7tix 258 13 to to TO cord-010398-5wot7tix 258 14 be be VB cord-010398-5wot7tix 258 15 efficacious efficacious JJ cord-010398-5wot7tix 258 16 in in IN cord-010398-5wot7tix 258 17 a a DT cord-010398-5wot7tix 258 18 wide wide JJ cord-010398-5wot7tix 258 19 range range NN cord-010398-5wot7tix 258 20 of of IN cord-010398-5wot7tix 258 21 these these DT cord-010398-5wot7tix 258 22 entities entity NNS cord-010398-5wot7tix 258 23 [ [ -LRB- cord-010398-5wot7tix 258 24 154 154 CD cord-010398-5wot7tix 258 25 ] ] -RRB- cord-010398-5wot7tix 258 26 . . . cord-010398-5wot7tix 259 1 The the DT cord-010398-5wot7tix 259 2 overall overall JJ cord-010398-5wot7tix 259 3 average average JJ cord-010398-5wot7tix 259 4 improvements improvement NNS cord-010398-5wot7tix 259 5 in in IN cord-010398-5wot7tix 259 6 fatigue fatigue NN cord-010398-5wot7tix 259 7 noted note VBN cord-010398-5wot7tix 259 8 with with IN cord-010398-5wot7tix 259 9 these these DT cord-010398-5wot7tix 259 10 classes class NNS cord-010398-5wot7tix 259 11 of of IN cord-010398-5wot7tix 259 12 drugs drug NNS cord-010398-5wot7tix 259 13 in in IN cord-010398-5wot7tix 259 14 FM FM NNP cord-010398-5wot7tix 259 15 is be VBZ cord-010398-5wot7tix 259 16 not not RB cord-010398-5wot7tix 259 17 as as RB cord-010398-5wot7tix 259 18 great great JJ cord-010398-5wot7tix 259 19 as as IN cord-010398-5wot7tix 259 20 the the DT cord-010398-5wot7tix 259 21 average average JJ cord-010398-5wot7tix 259 22 improvements improvement NNS cord-010398-5wot7tix 259 23 in in IN cord-010398-5wot7tix 259 24 pain pain NN cord-010398-5wot7tix 259 25 , , , cord-010398-5wot7tix 259 26 in in IN cord-010398-5wot7tix 259 27 part part NN cord-010398-5wot7tix 259 28 because because IN cord-010398-5wot7tix 259 29 fatigue fatigue NN cord-010398-5wot7tix 259 30 is be VBZ cord-010398-5wot7tix 259 31 a a DT cord-010398-5wot7tix 259 32 relatively relatively RB cord-010398-5wot7tix 259 33 common common JJ cord-010398-5wot7tix 259 34 adverse adverse JJ cord-010398-5wot7tix 259 35 effect effect NN cord-010398-5wot7tix 259 36 of of IN cord-010398-5wot7tix 259 37 all all DT cord-010398-5wot7tix 259 38 of of IN cord-010398-5wot7tix 259 39 these these DT cord-010398-5wot7tix 259 40 drugs drug NNS cord-010398-5wot7tix 259 41 , , , cord-010398-5wot7tix 259 42 leading lead VBG cord-010398-5wot7tix 259 43 to to IN cord-010398-5wot7tix 259 44 less less RBR cord-010398-5wot7tix 259 45 impressive impressive JJ cord-010398-5wot7tix 259 46 overall overall JJ cord-010398-5wot7tix 259 47 effects effect NNS cord-010398-5wot7tix 259 48 . . . cord-010398-5wot7tix 260 1 However however RB cord-010398-5wot7tix 260 2 , , , cord-010398-5wot7tix 260 3 when when WRB cord-010398-5wot7tix 260 4 patients patient NNS cord-010398-5wot7tix 260 5 with with IN cord-010398-5wot7tix 260 6 FM FM NNP cord-010398-5wot7tix 260 7 and and CC cord-010398-5wot7tix 260 8 CFS CFS NNP cord-010398-5wot7tix 260 9 have have VBP cord-010398-5wot7tix 260 10 a a DT cord-010398-5wot7tix 260 11 favorable favorable JJ cord-010398-5wot7tix 260 12 clinical clinical JJ cord-010398-5wot7tix 260 13 response response NN cord-010398-5wot7tix 260 14 to to IN cord-010398-5wot7tix 260 15 these these DT cord-010398-5wot7tix 260 16 medications medication NNS cord-010398-5wot7tix 260 17 ( ( -LRB- cord-010398-5wot7tix 260 18 generally generally RB cord-010398-5wot7tix 260 19 noted note VBN cord-010398-5wot7tix 260 20 in in IN cord-010398-5wot7tix 260 21 approximately approximately RB cord-010398-5wot7tix 260 22 one one CD cord-010398-5wot7tix 260 23 - - HYPH cord-010398-5wot7tix 260 24 third third NN cord-010398-5wot7tix 260 25 of of IN cord-010398-5wot7tix 260 26 patients patient NNS cord-010398-5wot7tix 260 27 ) ) -RRB- cord-010398-5wot7tix 261 1 there there EX cord-010398-5wot7tix 261 2 is be VBZ cord-010398-5wot7tix 261 3 typically typically RB cord-010398-5wot7tix 261 4 a a DT cord-010398-5wot7tix 261 5 global global JJ cord-010398-5wot7tix 261 6 improvement improvement NN cord-010398-5wot7tix 261 7 in in IN cord-010398-5wot7tix 261 8 all all DT cord-010398-5wot7tix 261 9 symptoms symptom NNS cord-010398-5wot7tix 261 10 , , , cord-010398-5wot7tix 261 11 including include VBG cord-010398-5wot7tix 261 12 fatigue fatigue NN cord-010398-5wot7tix 261 13 as as RB cord-010398-5wot7tix 261 14 well well RB cord-010398-5wot7tix 261 15 as as IN cord-010398-5wot7tix 261 16 pain pain NN cord-010398-5wot7tix 261 17 [ [ -LRB- cord-010398-5wot7tix 261 18 154 154 CD cord-010398-5wot7tix 261 19 ] ] -RRB- cord-010398-5wot7tix 261 20 [ [ -LRB- cord-010398-5wot7tix 261 21 155 155 CD cord-010398-5wot7tix 261 22 ] ] -RRB- cord-010398-5wot7tix 261 23 [ [ -LRB- cord-010398-5wot7tix 261 24 156 156 CD cord-010398-5wot7tix 261 25 ] ] -RRB- cord-010398-5wot7tix 261 26 . . . cord-010398-5wot7tix 262 1 This this DT cord-010398-5wot7tix 262 2 observation observation NN cord-010398-5wot7tix 262 3 would would MD cord-010398-5wot7tix 262 4 support support VB cord-010398-5wot7tix 262 5 the the DT cord-010398-5wot7tix 262 6 notion notion NN cord-010398-5wot7tix 262 7 that that IN cord-010398-5wot7tix 262 8 similar similar JJ cord-010398-5wot7tix 262 9 neurotransmitter neurotransmitter NN cord-010398-5wot7tix 262 10 disturbances disturbance NNS cord-010398-5wot7tix 262 11 can can MD cord-010398-5wot7tix 262 12 lead lead VB cord-010398-5wot7tix 262 13 to to IN cord-010398-5wot7tix 262 14 many many JJ cord-010398-5wot7tix 262 15 somatic somatic JJ cord-010398-5wot7tix 262 16 symptoms symptom NNS cord-010398-5wot7tix 262 17 , , , cord-010398-5wot7tix 262 18 including include VBG cord-010398-5wot7tix 262 19 both both CC cord-010398-5wot7tix 262 20 pain pain NN cord-010398-5wot7tix 262 21 and and CC cord-010398-5wot7tix 262 22 fatigue fatigue NN cord-010398-5wot7tix 262 23 . . . cord-010398-5wot7tix 263 1 Figure figure NN cord-010398-5wot7tix 263 2 4 4 CD cord-010398-5wot7tix 263 3 lists list VBZ cord-010398-5wot7tix 263 4 the the DT cord-010398-5wot7tix 263 5 classes class NNS cord-010398-5wot7tix 263 6 of of IN cord-010398-5wot7tix 263 7 drugs drug NNS cord-010398-5wot7tix 263 8 and and CC cord-010398-5wot7tix 263 9 their -PRON- PRP$ cord-010398-5wot7tix 263 10 level level NN cord-010398-5wot7tix 263 11 of of IN cord-010398-5wot7tix 263 12 evidence evidence NN cord-010398-5wot7tix 263 13 in in IN cord-010398-5wot7tix 263 14 FM FM NNP cord-010398-5wot7tix 263 15 . . . cord-010398-5wot7tix 264 1 Those those DT cord-010398-5wot7tix 264 2 drugs drug NNS cord-010398-5wot7tix 264 3 with with IN cord-010398-5wot7tix 264 4 the the DT cord-010398-5wot7tix 264 5 greatest great JJS cord-010398-5wot7tix 264 6 level level NN cord-010398-5wot7tix 264 7 of of IN cord-010398-5wot7tix 264 8 efficacy efficacy NN cord-010398-5wot7tix 264 9 in in IN cord-010398-5wot7tix 264 10 FM FM NNP cord-010398-5wot7tix 264 11 are be VBP cord-010398-5wot7tix 264 12 also also RB cord-010398-5wot7tix 264 13 being be VBG cord-010398-5wot7tix 264 14 shown show VBN cord-010398-5wot7tix 264 15 to to TO cord-010398-5wot7tix 264 16 work work VB cord-010398-5wot7tix 264 17 in in IN cord-010398-5wot7tix 264 18 subsets subset NNS cord-010398-5wot7tix 264 19 of of IN cord-010398-5wot7tix 264 20 patients patient NNS cord-010398-5wot7tix 264 21 with with IN cord-010398-5wot7tix 264 22 CSS css NN cord-010398-5wot7tix 264 23 . . . cord-010398-5wot7tix 265 1 More more RBR cord-010398-5wot7tix 265 2 importantly importantly RB cord-010398-5wot7tix 265 3 , , , cord-010398-5wot7tix 265 4 drugs drug NNS cord-010398-5wot7tix 265 5 such such JJ cord-010398-5wot7tix 265 6 as as IN cord-010398-5wot7tix 265 7 duloxetine duloxetine NNP cord-010398-5wot7tix 265 8 are be VBP cord-010398-5wot7tix 265 9 being be VBG cord-010398-5wot7tix 265 10 shown show VBN cord-010398-5wot7tix 265 11 to to TO cord-010398-5wot7tix 265 12 be be VB cord-010398-5wot7tix 265 13 effective effective JJ cord-010398-5wot7tix 265 14 in in IN cord-010398-5wot7tix 265 15 conditions condition NNS cord-010398-5wot7tix 265 16 such such JJ cord-010398-5wot7tix 265 17 as as IN cord-010398-5wot7tix 265 18 osteoarthritis osteoarthritis NN cord-010398-5wot7tix 265 19 and and CC cord-010398-5wot7tix 265 20 low low JJ cord-010398-5wot7tix 265 21 back back JJ cord-010398-5wot7tix 265 22 pain pain NN cord-010398-5wot7tix 265 23 , , , cord-010398-5wot7tix 265 24 demonstrating demonstrate VBG cord-010398-5wot7tix 265 25 the the DT cord-010398-5wot7tix 265 26 these these DT cord-010398-5wot7tix 265 27 central central JJ cord-010398-5wot7tix 265 28 mechanisms mechanism NNS cord-010398-5wot7tix 265 29 that that WDT cord-010398-5wot7tix 265 30 are be VBP cord-010398-5wot7tix 265 31 " " `` cord-010398-5wot7tix 265 32 front front JJ cord-010398-5wot7tix 265 33 and and CC cord-010398-5wot7tix 265 34 center center NN cord-010398-5wot7tix 265 35 " " '' cord-010398-5wot7tix 265 36 in in IN cord-010398-5wot7tix 265 37 patients patient NNS cord-010398-5wot7tix 265 38 with with IN cord-010398-5wot7tix 265 39 syndromes syndrome NNS cord-010398-5wot7tix 265 40 such such JJ cord-010398-5wot7tix 265 41 as as IN cord-010398-5wot7tix 265 42 FM FM NNP cord-010398-5wot7tix 265 43 may may MD cord-010398-5wot7tix 265 44 be be VB cord-010398-5wot7tix 265 45 also also RB cord-010398-5wot7tix 265 46 playing play VBG cord-010398-5wot7tix 265 47 prominent prominent JJ cord-010398-5wot7tix 265 48 roles role NNS cord-010398-5wot7tix 265 49 in in IN cord-010398-5wot7tix 265 50 conditions condition NNS cord-010398-5wot7tix 265 51 heretofore heretofore RB cord-010398-5wot7tix 265 52 thought think VBN cord-010398-5wot7tix 265 53 to to TO cord-010398-5wot7tix 265 54 be be VB cord-010398-5wot7tix 265 55 peripheral peripheral JJ cord-010398-5wot7tix 265 56 pain pain NN cord-010398-5wot7tix 265 57 syndromes syndrome NNS cord-010398-5wot7tix 265 58 . . . cord-010398-5wot7tix 266 1 However however RB cord-010398-5wot7tix 266 2 , , , cord-010398-5wot7tix 266 3 we -PRON- PRP cord-010398-5wot7tix 266 4 have have VBP cord-010398-5wot7tix 266 5 known know VBN cord-010398-5wot7tix 266 6 for for IN cord-010398-5wot7tix 266 7 some some DT cord-010398-5wot7tix 266 8 time time NN cord-010398-5wot7tix 266 9 that that WDT cord-010398-5wot7tix 266 10 hyperalgesia hyperalgesia NN cord-010398-5wot7tix 266 11 and and CC cord-010398-5wot7tix 266 12 manifestations manifestation NNS cord-010398-5wot7tix 266 13 of of IN cord-010398-5wot7tix 266 14 central central JJ cord-010398-5wot7tix 266 15 factors factor NNS cord-010398-5wot7tix 266 16 , , , cord-010398-5wot7tix 266 17 as as RB cord-010398-5wot7tix 266 18 well well RB cord-010398-5wot7tix 266 19 as as IN cord-010398-5wot7tix 266 20 various various JJ cord-010398-5wot7tix 266 21 other other JJ cord-010398-5wot7tix 266 22 indicators indicator NNS cord-010398-5wot7tix 266 23 of of IN cord-010398-5wot7tix 266 24 a a DT cord-010398-5wot7tix 266 25 wide wide JJ cord-010398-5wot7tix 266 26 range range NN cord-010398-5wot7tix 266 27 of of IN cord-010398-5wot7tix 266 28 " " `` cord-010398-5wot7tix 266 29 fibromyaglia fibromyaglia NNP cord-010398-5wot7tix 266 30 - - HYPH cord-010398-5wot7tix 266 31 ness ness NNP cord-010398-5wot7tix 266 32 , , , cord-010398-5wot7tix 266 33 " " '' cord-010398-5wot7tix 266 34 are be VBP cord-010398-5wot7tix 266 35 present present JJ cord-010398-5wot7tix 266 36 in in IN cord-010398-5wot7tix 266 37 conditions condition NNS cord-010398-5wot7tix 266 38 such such JJ cord-010398-5wot7tix 266 39 as as IN cord-010398-5wot7tix 266 40 osteoarthritis osteoarthritis NN cord-010398-5wot7tix 266 41 and and CC cord-010398-5wot7tix 266 42 low low JJ cord-010398-5wot7tix 266 43 back back JJ cord-010398-5wot7tix 266 44 pain pain NN cord-010398-5wot7tix 266 45 . . . cord-010398-5wot7tix 267 1 Any any DT cord-010398-5wot7tix 267 2 one one CD cord-010398-5wot7tix 267 3 of of IN cord-010398-5wot7tix 267 4 these these DT cord-010398-5wot7tix 267 5 classes class NNS cord-010398-5wot7tix 267 6 of of IN cord-010398-5wot7tix 267 7 drugs drug NNS cord-010398-5wot7tix 267 8 only only RB cord-010398-5wot7tix 267 9 works work VBZ cord-010398-5wot7tix 267 10 well well RB cord-010398-5wot7tix 267 11 in in IN cord-010398-5wot7tix 267 12 approximately approximately RB cord-010398-5wot7tix 267 13 one one CD cord-010398-5wot7tix 267 14 - - HYPH cord-010398-5wot7tix 267 15 third third NN cord-010398-5wot7tix 267 16 of of IN cord-010398-5wot7tix 267 17 patients patient NNS cord-010398-5wot7tix 267 18 , , , cord-010398-5wot7tix 267 19 a a DT cord-010398-5wot7tix 267 20 fact fact NN cord-010398-5wot7tix 267 21 entirely entirely RB cord-010398-5wot7tix 267 22 consistent consistent JJ cord-010398-5wot7tix 267 23 with with IN cord-010398-5wot7tix 267 24 findings finding NNS cord-010398-5wot7tix 267 25 supporting support VBG cord-010398-5wot7tix 267 26 the the DT cord-010398-5wot7tix 267 27 strongly strongly RB cord-010398-5wot7tix 267 28 genetic genetic JJ cord-010398-5wot7tix 267 29 , , , cord-010398-5wot7tix 267 30 but but CC cord-010398-5wot7tix 267 31 polygenic polygenic JJ cord-010398-5wot7tix 267 32 , , , cord-010398-5wot7tix 267 33 disorder disorder NN cord-010398-5wot7tix 267 34 . . . cord-010398-5wot7tix 268 1 Thus thus RB cord-010398-5wot7tix 268 2 , , , cord-010398-5wot7tix 268 3 clinicians clinician NNS cord-010398-5wot7tix 268 4 will will MD cord-010398-5wot7tix 268 5 need need VB cord-010398-5wot7tix 268 6 different different JJ cord-010398-5wot7tix 268 7 treatments treatment NNS cord-010398-5wot7tix 268 8 for for IN cord-010398-5wot7tix 268 9 different different JJ cord-010398-5wot7tix 268 10 patients patient NNS cord-010398-5wot7tix 268 11 . . . cord-010398-5wot7tix 269 1 Going go VBG cord-010398-5wot7tix 269 2 back back RB cord-010398-5wot7tix 269 3 to to IN cord-010398-5wot7tix 269 4 the the DT cord-010398-5wot7tix 269 5 " " `` cord-010398-5wot7tix 269 6 essential essential JJ cord-010398-5wot7tix 269 7 hypertension hypertension NN cord-010398-5wot7tix 269 8 of of IN cord-010398-5wot7tix 269 9 pain pain NN cord-010398-5wot7tix 269 10 processing processing NN cord-010398-5wot7tix 269 11 pathway pathway NN cord-010398-5wot7tix 269 12 " " '' cord-010398-5wot7tix 269 13 analogy analogy NN cord-010398-5wot7tix 269 14 , , , cord-010398-5wot7tix 269 15 just just RB cord-010398-5wot7tix 269 16 as as IN cord-010398-5wot7tix 269 17 we -PRON- PRP cord-010398-5wot7tix 269 18 use use VBP cord-010398-5wot7tix 269 19 8 8 CD cord-010398-5wot7tix 269 20 to to TO cord-010398-5wot7tix 269 21 10 10 CD cord-010398-5wot7tix 269 22 classes class NNS cord-010398-5wot7tix 269 23 of of IN cord-010398-5wot7tix 269 24 drugs drug NNS cord-010398-5wot7tix 269 25 acting act VBG cord-010398-5wot7tix 269 26 in in IN cord-010398-5wot7tix 269 27 different different JJ cord-010398-5wot7tix 269 28 body body NN cord-010398-5wot7tix 269 29 systems system NNS cord-010398-5wot7tix 269 30 and and CC cord-010398-5wot7tix 269 31 at at IN cord-010398-5wot7tix 269 32 different different JJ cord-010398-5wot7tix 269 33 molecular molecular JJ cord-010398-5wot7tix 269 34 targets target NNS cord-010398-5wot7tix 269 35 to to TO cord-010398-5wot7tix 269 36 control control VB cord-010398-5wot7tix 269 37 hypertension hypertension NN cord-010398-5wot7tix 269 38 , , , cord-010398-5wot7tix 269 39 and and CC cord-010398-5wot7tix 269 40 patients patient NNS cord-010398-5wot7tix 269 41 may may MD cord-010398-5wot7tix 269 42 respond respond VB cord-010398-5wot7tix 269 43 very very RB cord-010398-5wot7tix 269 44 well well RB cord-010398-5wot7tix 269 45 to to IN cord-010398-5wot7tix 269 46 one one CD cord-010398-5wot7tix 269 47 class class NN cord-010398-5wot7tix 269 48 of of IN cord-010398-5wot7tix 269 49 antihypertensive antihypertensive JJ cord-010398-5wot7tix 269 50 drug drug NN cord-010398-5wot7tix 269 51 but but CC cord-010398-5wot7tix 269 52 not not RB cord-010398-5wot7tix 269 53 another another DT cord-010398-5wot7tix 269 54 , , , cord-010398-5wot7tix 269 55 the the DT cord-010398-5wot7tix 269 56 same same JJ cord-010398-5wot7tix 269 57 is be VBZ cord-010398-5wot7tix 269 58 true true JJ cord-010398-5wot7tix 269 59 of of IN cord-010398-5wot7tix 269 60 CSS css NN cord-010398-5wot7tix 269 61 syndromes syndrome NNS cord-010398-5wot7tix 269 62 . . . cord-010398-5wot7tix 270 1 Patients patient NNS cord-010398-5wot7tix 270 2 may may MD cord-010398-5wot7tix 270 3 only only RB cord-010398-5wot7tix 270 4 respond respond VB cord-010398-5wot7tix 270 5 to to IN cord-010398-5wot7tix 270 6 one one CD cord-010398-5wot7tix 270 7 of of IN cord-010398-5wot7tix 270 8 these these DT cord-010398-5wot7tix 270 9 classes class NNS cord-010398-5wot7tix 270 10 of of IN cord-010398-5wot7tix 270 11 drugs drug NNS cord-010398-5wot7tix 270 12 or or CC cord-010398-5wot7tix 270 13 may may MD cord-010398-5wot7tix 270 14 often often RB cord-010398-5wot7tix 270 15 be be VB cord-010398-5wot7tix 270 16 in in IN cord-010398-5wot7tix 270 17 several several JJ cord-010398-5wot7tix 270 18 classes class NNS cord-010398-5wot7tix 270 19 of of IN cord-010398-5wot7tix 270 20 centrally centrally RB cord-010398-5wot7tix 270 21 acting act VBG cord-010398-5wot7tix 270 22 analgesics analgesic NNS cord-010398-5wot7tix 270 23 ( ( -LRB- cord-010398-5wot7tix 270 24 eg eg UH cord-010398-5wot7tix 270 25 , , , cord-010398-5wot7tix 270 26 a a DT cord-010398-5wot7tix 270 27 low low JJ cord-010398-5wot7tix 270 28 dose dose NN cord-010398-5wot7tix 270 29 of of IN cord-010398-5wot7tix 270 30 cyclobenzaprine cyclobenzaprine NN cord-010398-5wot7tix 270 31 at at IN cord-010398-5wot7tix 270 32 bedtime bedtime NN cord-010398-5wot7tix 270 33 , , , cord-010398-5wot7tix 270 34 pregabalin pregabalin NN cord-010398-5wot7tix 270 35 or or CC cord-010398-5wot7tix 270 36 gabapentin gabapentin NN cord-010398-5wot7tix 270 37 either either CC cord-010398-5wot7tix 270 38 just just RB cord-010398-5wot7tix 270 39 at at IN cord-010398-5wot7tix 270 40 bedtime bedtime NN cord-010398-5wot7tix 270 41 or or CC cord-010398-5wot7tix 270 42 twice twice RB cord-010398-5wot7tix 270 43 daily daily RB cord-010398-5wot7tix 270 44 , , , cord-010398-5wot7tix 270 45 and and CC cord-010398-5wot7tix 270 46 a a DT cord-010398-5wot7tix 270 47 serotonin serotonin NN cord-010398-5wot7tix 270 48 - - HYPH cord-010398-5wot7tix 270 49 norepineprine norepineprine JJ cord-010398-5wot7tix 270 50 reuptake reuptake NN cord-010398-5wot7tix 270 51 inhibitor inhibitor NN cord-010398-5wot7tix 270 52 such such JJ cord-010398-5wot7tix 270 53 as as IN cord-010398-5wot7tix 270 54 duloxetine duloxetine NNP cord-010398-5wot7tix 270 55 or or CC cord-010398-5wot7tix 270 56 milnacipran milnacipran NN cord-010398-5wot7tix 270 57 during during IN cord-010398-5wot7tix 270 58 the the DT cord-010398-5wot7tix 270 59 day day NN cord-010398-5wot7tix 270 60 ) ) -RRB- cord-010398-5wot7tix 270 61 . . . cord-010398-5wot7tix 271 1 However however RB cord-010398-5wot7tix 271 2 , , , cord-010398-5wot7tix 271 3 our -PRON- PRP$ cord-010398-5wot7tix 271 4 current current JJ cord-010398-5wot7tix 271 5 pharmacological pharmacological JJ cord-010398-5wot7tix 271 6 armamentarium armamentarium NN cord-010398-5wot7tix 271 7 is be VBZ cord-010398-5wot7tix 271 8 not not RB cord-010398-5wot7tix 271 9 nearly nearly RB cord-010398-5wot7tix 271 10 as as RB cord-010398-5wot7tix 271 11 well well RB cord-010398-5wot7tix 271 12 - - HYPH cord-010398-5wot7tix 271 13 developed develop VBN cord-010398-5wot7tix 271 14 for for IN cord-010398-5wot7tix 271 15 central central JJ cord-010398-5wot7tix 271 16 pain pain NN cord-010398-5wot7tix 271 17 as as IN cord-010398-5wot7tix 271 18 for for IN cord-010398-5wot7tix 271 19 essential essential JJ cord-010398-5wot7tix 271 20 hypertension hypertension NN cord-010398-5wot7tix 271 21 , , , cord-010398-5wot7tix 271 22 which which WDT cord-010398-5wot7tix 271 23 is be VBZ cord-010398-5wot7tix 271 24 likely likely RB cord-010398-5wot7tix 271 25 one one CD cord-010398-5wot7tix 271 26 of of IN cord-010398-5wot7tix 271 27 the the DT cord-010398-5wot7tix 271 28 reasons reason NNS cord-010398-5wot7tix 271 29 that that WDT cord-010398-5wot7tix 271 30 these these DT cord-010398-5wot7tix 271 31 syndromes syndrome NNS cord-010398-5wot7tix 271 32 are be VBP cord-010398-5wot7tix 271 33 often often RB cord-010398-5wot7tix 271 34 still still RB cord-010398-5wot7tix 271 35 difficult difficult JJ cord-010398-5wot7tix 271 36 to to TO cord-010398-5wot7tix 271 37 treat treat VB cord-010398-5wot7tix 271 38 . . . cord-010398-5wot7tix 272 1 Figure figure NN cord-010398-5wot7tix 272 2 4 4 CD cord-010398-5wot7tix 272 3 also also RB cord-010398-5wot7tix 272 4 points point VBZ cord-010398-5wot7tix 272 5 out out RP cord-010398-5wot7tix 272 6 that that IN cord-010398-5wot7tix 272 7 classes class NNS cord-010398-5wot7tix 272 8 of of IN cord-010398-5wot7tix 272 9 drugs drug NNS cord-010398-5wot7tix 272 10 that that WDT cord-010398-5wot7tix 272 11 are be VBP cord-010398-5wot7tix 272 12 quite quite RB cord-010398-5wot7tix 272 13 effective effective JJ cord-010398-5wot7tix 272 14 for for IN cord-010398-5wot7tix 272 15 " " `` cord-010398-5wot7tix 272 16 peripheral peripheral JJ cord-010398-5wot7tix 272 17 " " '' cord-010398-5wot7tix 272 18 pain pain NN cord-010398-5wot7tix 272 19 as as IN cord-010398-5wot7tix 272 20 the the DT cord-010398-5wot7tix 272 21 result result NN cord-010398-5wot7tix 272 22 of of IN cord-010398-5wot7tix 272 23 damage damage NN cord-010398-5wot7tix 272 24 or or CC cord-010398-5wot7tix 272 25 inflammation inflammation NN cord-010398-5wot7tix 272 26 in in IN cord-010398-5wot7tix 272 27 peripheral peripheral JJ cord-010398-5wot7tix 272 28 tissues tissue NNS cord-010398-5wot7tix 272 29 , , , cord-010398-5wot7tix 272 30 such such JJ cord-010398-5wot7tix 272 31 as as IN cord-010398-5wot7tix 272 32 nonsteroidal nonsteroidal JJ cord-010398-5wot7tix 272 33 antiinflammatory antiinflammatory JJ cord-010398-5wot7tix 272 34 drugs drug NNS cord-010398-5wot7tix 272 35 and and CC cord-010398-5wot7tix 272 36 opioids opioid NNS cord-010398-5wot7tix 272 37 , , , cord-010398-5wot7tix 272 38 are be VBP cord-010398-5wot7tix 272 39 not not RB cord-010398-5wot7tix 272 40 effective effective JJ cord-010398-5wot7tix 272 41 analgesics analgesic NNS cord-010398-5wot7tix 272 42 in in IN cord-010398-5wot7tix 272 43 central central JJ cord-010398-5wot7tix 272 44 pain pain NN cord-010398-5wot7tix 272 45 states state NNS cord-010398-5wot7tix 272 46 . . . cord-010398-5wot7tix 273 1 There there EX cord-010398-5wot7tix 273 2 are be VBP cord-010398-5wot7tix 273 3 even even RB cord-010398-5wot7tix 273 4 data datum NNS cord-010398-5wot7tix 273 5 suggesting suggest VBG cord-010398-5wot7tix 273 6 that that IN cord-010398-5wot7tix 273 7 administering administer VBG cord-010398-5wot7tix 273 8 opioids opioid NNS cord-010398-5wot7tix 273 9 to to IN cord-010398-5wot7tix 273 10 patients patient NNS cord-010398-5wot7tix 273 11 with with IN cord-010398-5wot7tix 273 12 central central JJ cord-010398-5wot7tix 273 13 pain pain NN cord-010398-5wot7tix 273 14 states state NNS cord-010398-5wot7tix 273 15 could could MD cord-010398-5wot7tix 273 16 worsen worsen VB cord-010398-5wot7tix 273 17 their -PRON- PRP$ cord-010398-5wot7tix 273 18 pain pain NN cord-010398-5wot7tix 273 19 by by IN cord-010398-5wot7tix 273 20 leading lead VBG cord-010398-5wot7tix 273 21 to to IN cord-010398-5wot7tix 273 22 opioid opioid NN cord-010398-5wot7tix 273 23 - - HYPH cord-010398-5wot7tix 273 24 induced induce VBN cord-010398-5wot7tix 273 25 hyperalgesia hyperalgesia NN cord-010398-5wot7tix 273 26 , , , cord-010398-5wot7tix 273 27 which which WDT cord-010398-5wot7tix 273 28 could could MD cord-010398-5wot7tix 273 29 augment augment VB cord-010398-5wot7tix 273 30 and and CC cord-010398-5wot7tix 273 31 worsen worsen VB cord-010398-5wot7tix 273 32 the the DT cord-010398-5wot7tix 273 33 baseline baseline JJ cord-010398-5wot7tix 273 34 hyperagesia hyperagesia NNS cord-010398-5wot7tix 273 35 that that WDT cord-010398-5wot7tix 273 36 may may MD cord-010398-5wot7tix 273 37 be be VB cord-010398-5wot7tix 273 38 playing play VBG cord-010398-5wot7tix 273 39 a a DT cord-010398-5wot7tix 273 40 central central JJ cord-010398-5wot7tix 273 41 pathogenic pathogenic JJ cord-010398-5wot7tix 273 42 role role NN cord-010398-5wot7tix 273 43 in in IN cord-010398-5wot7tix 273 44 these these DT cord-010398-5wot7tix 273 45 conditions condition NNS cord-010398-5wot7tix 273 46 . . . cord-010398-5wot7tix 274 1 Just just RB cord-010398-5wot7tix 274 2 as as IN cord-010398-5wot7tix 274 3 many many JJ cord-010398-5wot7tix 274 4 pharmacological pharmacological JJ cord-010398-5wot7tix 274 5 therapies therapy NNS cord-010398-5wot7tix 274 6 work work VBP cord-010398-5wot7tix 274 7 across across IN cord-010398-5wot7tix 274 8 all all DT cord-010398-5wot7tix 274 9 or or CC cord-010398-5wot7tix 274 10 most most JJS cord-010398-5wot7tix 274 11 of of IN cord-010398-5wot7tix 274 12 these these DT cord-010398-5wot7tix 274 13 conditions condition NNS cord-010398-5wot7tix 274 14 , , , cord-010398-5wot7tix 274 15 similarly similarly RB cord-010398-5wot7tix 274 16 , , , cord-010398-5wot7tix 274 17 nonpharmacological nonpharmacological JJ cord-010398-5wot7tix 274 18 therapies therapy NNS cord-010398-5wot7tix 274 19 such such JJ cord-010398-5wot7tix 274 20 as as IN cord-010398-5wot7tix 274 21 education education NN cord-010398-5wot7tix 274 22 , , , cord-010398-5wot7tix 274 23 exercise exercise NN cord-010398-5wot7tix 274 24 , , , cord-010398-5wot7tix 274 25 and and CC cord-010398-5wot7tix 274 26 CBT CBT NNP cord-010398-5wot7tix 274 27 have have VBP cord-010398-5wot7tix 274 28 been be VBN cord-010398-5wot7tix 274 29 demonstrated demonstrate VBN cord-010398-5wot7tix 274 30 to to TO cord-010398-5wot7tix 274 31 be be VB cord-010398-5wot7tix 274 32 effective effective JJ cord-010398-5wot7tix 274 33 across across IN cord-010398-5wot7tix 274 34 nearly nearly RB cord-010398-5wot7tix 274 35 all all DT cord-010398-5wot7tix 274 36 of of IN cord-010398-5wot7tix 274 37 the the DT cord-010398-5wot7tix 274 38 CSS css NN cord-010398-5wot7tix 274 39 conditions condition NNS cord-010398-5wot7tix 274 40 [ [ -LRB- cord-010398-5wot7tix 274 41 157 157 CD cord-010398-5wot7tix 274 42 ] ] -RRB- cord-010398-5wot7tix 274 43 [ [ -LRB- cord-010398-5wot7tix 274 44 158 158 CD cord-010398-5wot7tix 274 45 ] ] -RRB- cord-010398-5wot7tix 274 46 [ [ -LRB- cord-010398-5wot7tix 274 47 159 159 CD cord-010398-5wot7tix 274 48 ] ] -RRB- cord-010398-5wot7tix 274 49 . . . cord-010398-5wot7tix 275 1 Both both DT cord-010398-5wot7tix 275 2 exercise exercise NN cord-010398-5wot7tix 275 3 and and CC cord-010398-5wot7tix 275 4 CBT CBT NNP cord-010398-5wot7tix 275 5 have have VBP cord-010398-5wot7tix 275 6 wide wide JJ cord-010398-5wot7tix 275 7 acceptance acceptance NN cord-010398-5wot7tix 275 8 and and CC cord-010398-5wot7tix 275 9 are be VBP cord-010398-5wot7tix 275 10 supported support VBN cord-010398-5wot7tix 275 11 by by IN cord-010398-5wot7tix 275 12 RCTs rct NNS cord-010398-5wot7tix 275 13 in in IN cord-010398-5wot7tix 275 14 CFS CFS NNP cord-010398-5wot7tix 275 15 . . . cord-010398-5wot7tix 276 1 When when WRB cord-010398-5wot7tix 276 2 prescribing prescribe VBG cord-010398-5wot7tix 276 3 exercise exercise NN cord-010398-5wot7tix 276 4 in in IN cord-010398-5wot7tix 276 5 CFS CFS NNP cord-010398-5wot7tix 276 6 , , , cord-010398-5wot7tix 276 7 it -PRON- PRP cord-010398-5wot7tix 276 8 is be VBZ cord-010398-5wot7tix 276 9 important important JJ cord-010398-5wot7tix 276 10 to to TO cord-010398-5wot7tix 276 11 realize realize VB cord-010398-5wot7tix 276 12 that that IN cord-010398-5wot7tix 276 13 these these DT cord-010398-5wot7tix 276 14 patients patient NNS cord-010398-5wot7tix 276 15 are be VBP cord-010398-5wot7tix 276 16 different different JJ cord-010398-5wot7tix 276 17 than than IN cord-010398-5wot7tix 276 18 healthy healthy JJ cord-010398-5wot7tix 276 19 ones one NNS cord-010398-5wot7tix 276 20 . . . cord-010398-5wot7tix 277 1 The the DT cord-010398-5wot7tix 277 2 physiological physiological JJ cord-010398-5wot7tix 277 3 cost cost NN cord-010398-5wot7tix 277 4 of of IN cord-010398-5wot7tix 277 5 walking walking NN cord-010398-5wot7tix 277 6 is be VBZ cord-010398-5wot7tix 277 7 significantly significantly RB cord-010398-5wot7tix 277 8 greater great JJR cord-010398-5wot7tix 277 9 for for IN cord-010398-5wot7tix 277 10 people people NNS cord-010398-5wot7tix 277 11 with with IN cord-010398-5wot7tix 277 12 CFS cfs NN cord-010398-5wot7tix 277 13 compared compare VBN cord-010398-5wot7tix 277 14 with with IN cord-010398-5wot7tix 277 15 healthy healthy JJ cord-010398-5wot7tix 277 16 subjects subject NNS cord-010398-5wot7tix 277 17 . . . cord-010398-5wot7tix 278 1 The the DT cord-010398-5wot7tix 278 2 reasons reason NNS cord-010398-5wot7tix 278 3 _SP cord-010398-5wot7tix 278 4 ■ ■ NNP cord-010398-5wot7tix 278 5 Dual dual JJ cord-010398-5wot7tix 278 6 reuptake reuptake JJ cord-010398-5wot7tix 278 7 inhibitors inhibitor NNS cord-010398-5wot7tix 278 8 such such JJ cord-010398-5wot7tix 278 9 as as IN cord-010398-5wot7tix 278 10 ■ ■ NFP cord-010398-5wot7tix 278 11 Tricyclic tricyclic NN cord-010398-5wot7tix 278 12 compounds compound NNS cord-010398-5wot7tix 278 13 ( ( -LRB- cord-010398-5wot7tix 278 14 amitriptyline amitriptyline NN cord-010398-5wot7tix 278 15 , , , cord-010398-5wot7tix 278 16 cyclobenzaprine cyclobenzaprine NN cord-010398-5wot7tix 278 17 ) ) -RRB- cord-010398-5wot7tix 278 18 ■ ■ NFP cord-010398-5wot7tix 278 19 SNRIs snri NNS cord-010398-5wot7tix 278 20 and and CC cord-010398-5wot7tix 278 21 NSRIs nsri NNS cord-010398-5wot7tix 278 22 ( ( -LRB- cord-010398-5wot7tix 278 23 milnacipran milnacipran NNP cord-010398-5wot7tix 278 24 , , , cord-010398-5wot7tix 278 25 duloxetine duloxetine NN cord-010398-5wot7tix 278 26 , , , cord-010398-5wot7tix 278 27 venlafaxine venlafaxine NN cord-010398-5wot7tix 278 28 ? ? . cord-010398-5wot7tix 278 29 ) ) -RRB- cord-010398-5wot7tix 279 1 ■ ■ NFP cord-010398-5wot7tix 279 2 Anticonvulsants Anticonvulsants NNP cord-010398-5wot7tix 279 3 ( ( -LRB- cord-010398-5wot7tix 279 4 e.g. e.g. RB cord-010398-5wot7tix 279 5 , , , cord-010398-5wot7tix 279 6 pregabalin pregabalin NN cord-010398-5wot7tix 279 7 , , , cord-010398-5wot7tix 279 8 gabapentin gabapentin NN cord-010398-5wot7tix 279 9 ) ) -RRB- cord-010398-5wot7tix 279 10 ■ ■ NFP cord-010398-5wot7tix 279 11 Tramadol Tramadol NNP cord-010398-5wot7tix 279 12 ■ ■ . cord-010398-5wot7tix 279 13 Selective selective JJ cord-010398-5wot7tix 279 14 serotonin serotonin NN cord-010398-5wot7tix 279 15 reuptake reuptake NN cord-010398-5wot7tix 279 16 inhibitors inhibitor NNS cord-010398-5wot7tix 279 17 ( ( -LRB- cord-010398-5wot7tix 279 18 SSRIs ssri NNS cord-010398-5wot7tix 279 19 ) ) -RRB- cord-010398-5wot7tix 279 20 ■ ■ NFP cord-010398-5wot7tix 279 21 Gamma Gamma NNP cord-010398-5wot7tix 279 22 hydroxybutyrate hydroxybutyrate NN cord-010398-5wot7tix 279 23 ■ ■ NFP cord-010398-5wot7tix 279 24 Dopamine dopamine NN cord-010398-5wot7tix 279 25 agonists agonist NNS cord-010398-5wot7tix 280 1 Weak weak JJ cord-010398-5wot7tix 280 2 Evidence Evidence NNP cord-010398-5wot7tix 280 3 ■ ■ NNP cord-010398-5wot7tix 280 4 Growth growth NN cord-010398-5wot7tix 280 5 hormone hormone NN cord-010398-5wot7tix 280 6 , , , cord-010398-5wot7tix 280 7 5-hydroxytryptamine 5-hydroxytryptamine CD cord-010398-5wot7tix 280 8 , , , cord-010398-5wot7tix 280 9 tropisetron tropisetron NNP cord-010398-5wot7tix 280 10 , , , cord-010398-5wot7tix 280 11 S s NN cord-010398-5wot7tix 280 12 - - HYPH cord-010398-5wot7tix 280 13 adenosyl- adenosyl- NNP cord-010398-5wot7tix 281 1 L l NN cord-010398-5wot7tix 281 2 - - HYPH cord-010398-5wot7tix 281 3 methionine methionine JJ cord-010398-5wot7tix 281 4 ( ( -LRB- cord-010398-5wot7tix 281 5 SAMe same JJ cord-010398-5wot7tix 281 6 ) ) -RRB- cord-010398-5wot7tix 281 7 ■ ■ NFP cord-010398-5wot7tix 281 8 Opioids opioid NNS cord-010398-5wot7tix 281 9 , , , cord-010398-5wot7tix 281 10 corticosteroids corticosteroid NNS cord-010398-5wot7tix 281 11 , , , cord-010398-5wot7tix 281 12 nonsteroidal nonsteroidal JJ cord-010398-5wot7tix 281 13 anti anti JJ cord-010398-5wot7tix 281 14 - - JJ cord-010398-5wot7tix 281 15 inflammatory inflammatory JJ cord-010398-5wot7tix 281 16 drugs drug NNS cord-010398-5wot7tix 281 17 , , , cord-010398-5wot7tix 281 18 benzodiazepine benzodiazepine NN cord-010398-5wot7tix 281 19 and and CC cord-010398-5wot7tix 281 20 nonbenzodiazepine nonbenzodiazepine NNP cord-010398-5wot7tix 281 21 hypnotics hypnotics NNPS cord-010398-5wot7tix 281 22 , , , cord-010398-5wot7tix 281 23 guanifenesin guanifenesin NNP cord-010398-5wot7tix 281 24 for for IN cord-010398-5wot7tix 281 25 these these DT cord-010398-5wot7tix 281 26 greater great JJR cord-010398-5wot7tix 281 27 energy energy NN cord-010398-5wot7tix 281 28 demands demand NNS cord-010398-5wot7tix 281 29 for for IN cord-010398-5wot7tix 281 30 walking walk VBG cord-010398-5wot7tix 281 31 in in IN cord-010398-5wot7tix 281 32 those those DT cord-010398-5wot7tix 281 33 with with IN cord-010398-5wot7tix 281 34 CFS CFS NNP cord-010398-5wot7tix 281 35 have have VBP cord-010398-5wot7tix 281 36 yet yet RB cord-010398-5wot7tix 281 37 to to TO cord-010398-5wot7tix 281 38 be be VB cord-010398-5wot7tix 281 39 fully fully RB cord-010398-5wot7tix 281 40 elucidated elucidate VBN cord-010398-5wot7tix 281 41 , , , cord-010398-5wot7tix 281 42 but but CC cord-010398-5wot7tix 281 43 research research NN cord-010398-5wot7tix 281 44 suggests suggest VBZ cord-010398-5wot7tix 281 45 the the DT cord-010398-5wot7tix 281 46 physiological physiological JJ cord-010398-5wot7tix 281 47 need need NN cord-010398-5wot7tix 281 48 for for IN cord-010398-5wot7tix 281 49 very very RB cord-010398-5wot7tix 281 50 slow slow JJ cord-010398-5wot7tix 281 51 , , , cord-010398-5wot7tix 281 52 graded grade VBN cord-010398-5wot7tix 281 53 exercise exercise NN cord-010398-5wot7tix 281 54 programs program NNS cord-010398-5wot7tix 281 55 to to TO cord-010398-5wot7tix 281 56 treat treat VB cord-010398-5wot7tix 281 57 CFS CFS NNP cord-010398-5wot7tix 281 58 and and CC cord-010398-5wot7tix 281 59 other other JJ cord-010398-5wot7tix 281 60 related related JJ cord-010398-5wot7tix 281 61 conditions condition NNS cord-010398-5wot7tix 281 62 [ [ -LRB- cord-010398-5wot7tix 281 63 160 160 CD cord-010398-5wot7tix 281 64 , , , cord-010398-5wot7tix 281 65 161 161 CD cord-010398-5wot7tix 281 66 ] ] -RRB- cord-010398-5wot7tix 281 67 . . . cord-010398-5wot7tix 282 1 Light light NN cord-010398-5wot7tix 282 2 and and CC cord-010398-5wot7tix 282 3 colleagues colleague NNS cord-010398-5wot7tix 282 4 have have VBP cord-010398-5wot7tix 282 5 recently recently RB cord-010398-5wot7tix 282 6 demonstrated demonstrate VBN cord-010398-5wot7tix 282 7 that that IN cord-010398-5wot7tix 282 8 after after IN cord-010398-5wot7tix 282 9 moderate moderate JJ cord-010398-5wot7tix 282 10 exercise exercise NN cord-010398-5wot7tix 282 11 , , , cord-010398-5wot7tix 282 12 CFS CFS NNP cord-010398-5wot7tix 282 13 and and CC cord-010398-5wot7tix 282 14 CFS CFS NNP cord-010398-5wot7tix 282 15 - - HYPH cord-010398-5wot7tix 282 16 FMS FMS NNP cord-010398-5wot7tix 282 17 patients patient NNS cord-010398-5wot7tix 282 18 show show VBP cord-010398-5wot7tix 282 19 enhanced enhanced JJ cord-010398-5wot7tix 282 20 gene gene NN cord-010398-5wot7tix 282 21 expression expression NN cord-010398-5wot7tix 282 22 for for IN cord-010398-5wot7tix 282 23 receptors receptor NNS cord-010398-5wot7tix 282 24 detecting detect VBG cord-010398-5wot7tix 282 25 muscle muscle NN cord-010398-5wot7tix 282 26 metabolites metabolite NNS cord-010398-5wot7tix 282 27 and and CC cord-010398-5wot7tix 282 28 for for IN cord-010398-5wot7tix 282 29 sympathetic sympathetic JJ cord-010398-5wot7tix 282 30 nervous nervous JJ cord-010398-5wot7tix 282 31 system system NN cord-010398-5wot7tix 282 32 activation activation NN cord-010398-5wot7tix 282 33 [ [ -LRB- cord-010398-5wot7tix 282 34 162 162 CD cord-010398-5wot7tix 282 35 ] ] -RRB- cord-010398-5wot7tix 282 36 . . . cord-010398-5wot7tix 283 1 This this DT cord-010398-5wot7tix 283 2 finding finding NN cord-010398-5wot7tix 283 3 supports support VBZ cord-010398-5wot7tix 283 4 the the DT cord-010398-5wot7tix 283 5 need need NN cord-010398-5wot7tix 283 6 for for IN cord-010398-5wot7tix 283 7 a a DT cord-010398-5wot7tix 283 8 " " `` cord-010398-5wot7tix 283 9 start start VB cord-010398-5wot7tix 283 10 low low JJ cord-010398-5wot7tix 283 11 , , , cord-010398-5wot7tix 283 12 go go VB cord-010398-5wot7tix 283 13 slow slow JJ cord-010398-5wot7tix 283 14 " " `` cord-010398-5wot7tix 283 15 therapeutic therapeutic JJ cord-010398-5wot7tix 283 16 approach approach NN cord-010398-5wot7tix 283 17 to to TO cord-010398-5wot7tix 283 18 exercise exercise VB cord-010398-5wot7tix 283 19 in in IN cord-010398-5wot7tix 283 20 CFS CFS NNP cord-010398-5wot7tix 283 21 , , , cord-010398-5wot7tix 283 22 especially especially RB cord-010398-5wot7tix 283 23 because because IN cord-010398-5wot7tix 283 24 exacerbations exacerbation NNS cord-010398-5wot7tix 283 25 after after IN cord-010398-5wot7tix 283 26 overactivity overactivity NN cord-010398-5wot7tix 283 27 are be VBP cord-010398-5wot7tix 283 28 very very RB cord-010398-5wot7tix 283 29 common common JJ cord-010398-5wot7tix 283 30 . . . cord-010398-5wot7tix 284 1 In in IN cord-010398-5wot7tix 284 2 the the DT cord-010398-5wot7tix 284 3 past past JJ cord-010398-5wot7tix 284 4 few few JJ cord-010398-5wot7tix 284 5 decades decade NNS cord-010398-5wot7tix 284 6 , , , cord-010398-5wot7tix 284 7 our -PRON- PRP$ cord-010398-5wot7tix 284 8 understanding understanding NN cord-010398-5wot7tix 284 9 of of IN cord-010398-5wot7tix 284 10 CFS CFS NNP cord-010398-5wot7tix 284 11 has have VBZ cord-010398-5wot7tix 284 12 evolved evolve VBN cord-010398-5wot7tix 284 13 significantly significantly RB cord-010398-5wot7tix 284 14 , , , cord-010398-5wot7tix 284 15 as as IN cord-010398-5wot7tix 284 16 has have VBZ cord-010398-5wot7tix 284 17 our -PRON- PRP$ cord-010398-5wot7tix 284 18 understanding understanding NN cord-010398-5wot7tix 284 19 of of IN cord-010398-5wot7tix 284 20 related related JJ cord-010398-5wot7tix 284 21 conditions condition NNS cord-010398-5wot7tix 284 22 . . . cord-010398-5wot7tix 285 1 CFS CFS NNP cord-010398-5wot7tix 285 2 is be VBZ cord-010398-5wot7tix 285 3 a a DT cord-010398-5wot7tix 285 4 condition condition NN cord-010398-5wot7tix 285 5 that that WDT cord-010398-5wot7tix 285 6 has have VBZ cord-010398-5wot7tix 285 7 strong strong JJ cord-010398-5wot7tix 285 8 biological biological JJ cord-010398-5wot7tix 285 9 underpinnings underpinning NNS cord-010398-5wot7tix 285 10 and and CC cord-010398-5wot7tix 285 11 shares share NNS cord-010398-5wot7tix 285 12 pathogenic pathogenic JJ cord-010398-5wot7tix 285 13 features feature NNS cord-010398-5wot7tix 285 14 and and CC cord-010398-5wot7tix 285 15 response response NN cord-010398-5wot7tix 285 16 to to IN cord-010398-5wot7tix 285 17 treatment treatment NN cord-010398-5wot7tix 285 18 with with IN cord-010398-5wot7tix 285 19 many many JJ cord-010398-5wot7tix 285 20 other other JJ cord-010398-5wot7tix 285 21 syndromes syndrome NNS cord-010398-5wot7tix 285 22 characterized characterize VBN cord-010398-5wot7tix 285 23 by by IN cord-010398-5wot7tix 285 24 clusters cluster NNS cord-010398-5wot7tix 285 25 of of IN cord-010398-5wot7tix 285 26 multifocal multifocal JJ cord-010398-5wot7tix 285 27 pain pain NN cord-010398-5wot7tix 285 28 , , , cord-010398-5wot7tix 285 29 fatigue fatigue NN cord-010398-5wot7tix 285 30 , , , cord-010398-5wot7tix 285 31 and and CC cord-010398-5wot7tix 285 32 other other JJ cord-010398-5wot7tix 285 33 somatic somatic JJ cord-010398-5wot7tix 285 34 symptoms symptom NNS cord-010398-5wot7tix 285 35 . . . cord-010398-5wot7tix 286 1 A a DT cord-010398-5wot7tix 286 2 better well JJR cord-010398-5wot7tix 286 3 understanding understanding NN cord-010398-5wot7tix 286 4 of of IN cord-010398-5wot7tix 286 5 the the DT cord-010398-5wot7tix 286 6 underlying underlie VBG cord-010398-5wot7tix 286 7 mechanisms mechanism NNS cord-010398-5wot7tix 286 8 and and CC cord-010398-5wot7tix 286 9 most most RBS cord-010398-5wot7tix 286 10 effective effective JJ cord-010398-5wot7tix 286 11 treatment treatment NN cord-010398-5wot7tix 286 12 for for IN cord-010398-5wot7tix 286 13 this this DT cord-010398-5wot7tix 286 14 spectrum spectrum NN cord-010398-5wot7tix 286 15 of of IN cord-010398-5wot7tix 286 16 illnesses illness NNS cord-010398-5wot7tix 286 17 is be VBZ cord-010398-5wot7tix 286 18 critical critical JJ cord-010398-5wot7tix 286 19 to to TO cord-010398-5wot7tix 286 20 support support VB cord-010398-5wot7tix 286 21 clinicians clinician NNS cord-010398-5wot7tix 286 22 treating treat VBG cord-010398-5wot7tix 286 23 these these DT cord-010398-5wot7tix 286 24 very very RB cord-010398-5wot7tix 286 25 common common JJ cord-010398-5wot7tix 286 26 conditions condition NNS cord-010398-5wot7tix 286 27 . . . cord-010398-5wot7tix 287 1 There there EX cord-010398-5wot7tix 287 2 are be VBP cord-010398-5wot7tix 287 3 clearly clearly RB cord-010398-5wot7tix 287 4 subsets subset NNS cord-010398-5wot7tix 287 5 of of IN cord-010398-5wot7tix 287 6 patients patient NNS cord-010398-5wot7tix 287 7 with with IN cord-010398-5wot7tix 287 8 CFS CFS NNP cord-010398-5wot7tix 287 9 that that WDT cord-010398-5wot7tix 287 10 have have VBP cord-010398-5wot7tix 287 11 differing differ VBG cord-010398-5wot7tix 287 12 underlying underlie VBG cord-010398-5wot7tix 287 13 reasons reason NNS cord-010398-5wot7tix 287 14 for for IN cord-010398-5wot7tix 287 15 their -PRON- PRP$ cord-010398-5wot7tix 287 16 symptoms symptom NNS cord-010398-5wot7tix 287 17 , , , cord-010398-5wot7tix 287 18 and and CC cord-010398-5wot7tix 287 19 current current JJ cord-010398-5wot7tix 287 20 efforts effort NNS cord-010398-5wot7tix 287 21 are be VBP cord-010398-5wot7tix 287 22 focused focus VBN cord-010398-5wot7tix 287 23 on on IN cord-010398-5wot7tix 287 24 identifying identify VBG cord-010398-5wot7tix 287 25 subsets subset NNS cord-010398-5wot7tix 287 26 that that WDT cord-010398-5wot7tix 287 27 would would MD cord-010398-5wot7tix 287 28 preferentially preferentially RB cord-010398-5wot7tix 287 29 respond respond VB cord-010398-5wot7tix 287 30 to to IN cord-010398-5wot7tix 287 31 therapies therapy NNS cord-010398-5wot7tix 287 32 directed direct VBN cord-010398-5wot7tix 287 33 at at IN cord-010398-5wot7tix 287 34 root root NN cord-010398-5wot7tix 287 35 causes cause NNS cord-010398-5wot7tix 287 36 . . . cord-010398-5wot7tix 288 1 A a DT cord-010398-5wot7tix 288 2 chronic chronic JJ cord-010398-5wot7tix 288 3 illness illness NN cord-010398-5wot7tix 288 4 characterized characterize VBN cord-010398-5wot7tix 288 5 by by IN cord-010398-5wot7tix 288 6 fatigue fatigue NN cord-010398-5wot7tix 288 7 , , , cord-010398-5wot7tix 288 8 neurologic neurologic JJ cord-010398-5wot7tix 288 9 and and CC cord-010398-5wot7tix 288 10 immunologic immunologic JJ cord-010398-5wot7tix 288 11 disorders disorder NNS cord-010398-5wot7tix 288 12 , , , cord-010398-5wot7tix 288 13 and and CC cord-010398-5wot7tix 288 14 active active JJ cord-010398-5wot7tix 288 15 human human JJ cord-010398-5wot7tix 288 16 herpesvirus herpesvirus NN cord-010398-5wot7tix 288 17 type type NN cord-010398-5wot7tix 288 18 6 6 CD cord-010398-5wot7tix 288 19 infection infection NN cord-010398-5wot7tix 288 20 Seroepidemiology Seroepidemiology NNP cord-010398-5wot7tix 288 21 of of IN cord-010398-5wot7tix 288 22 chronic chronic JJ cord-010398-5wot7tix 288 23 fatigue fatigue NN cord-010398-5wot7tix 288 24 syndrome syndrome NN cord-010398-5wot7tix 288 25 : : : cord-010398-5wot7tix 288 26 A a DT cord-010398-5wot7tix 288 27 case case NN cord-010398-5wot7tix 288 28 - - HYPH cord-010398-5wot7tix 288 29 control control NN cord-010398-5wot7tix 288 30 study study NN cord-010398-5wot7tix 288 31 Immune immune JJ cord-010398-5wot7tix 288 32 responses response NNS cord-010398-5wot7tix 288 33 associated associate VBN cord-010398-5wot7tix 288 34 with with IN cord-010398-5wot7tix 288 35 chronic chronic JJ cord-010398-5wot7tix 288 36 fatigue fatigue NN cord-010398-5wot7tix 288 37 syndrome syndrome NN cord-010398-5wot7tix 288 38 : : : cord-010398-5wot7tix 288 39 A a DT cord-010398-5wot7tix 288 40 case case NN cord-010398-5wot7tix 288 41 - - HYPH cord-010398-5wot7tix 288 42 control control NN cord-010398-5wot7tix 288 43 study study NN cord-010398-5wot7tix 288 44 Factor Factor NNP cord-010398-5wot7tix 288 45 analysis analysis NN cord-010398-5wot7tix 288 46 of of IN cord-010398-5wot7tix 288 47 unexplained unexplained JJ cord-010398-5wot7tix 288 48 severe severe JJ cord-010398-5wot7tix 288 49 fatigue fatigue NN cord-010398-5wot7tix 288 50 and and CC cord-010398-5wot7tix 288 51 interrelated interrelated JJ cord-010398-5wot7tix 288 52 symptoms symptom NNS cord-010398-5wot7tix 288 53 : : : cord-010398-5wot7tix 288 54 Overlap overlap VB cord-010398-5wot7tix 288 55 with with IN cord-010398-5wot7tix 288 56 criteria criterion NNS cord-010398-5wot7tix 288 57 for for IN cord-010398-5wot7tix 288 58 chronic chronic JJ cord-010398-5wot7tix 288 59 fatigue fatigue NN cord-010398-5wot7tix 288 60 syndrome syndrome NNP cord-010398-5wot7tix 288 61 Association Association NNP cord-010398-5wot7tix 288 62 of of IN cord-010398-5wot7tix 288 63 peripheral peripheral JJ cord-010398-5wot7tix 288 64 inflammatory inflammatory JJ cord-010398-5wot7tix 288 65 markers marker NNS cord-010398-5wot7tix 288 66 with with IN cord-010398-5wot7tix 288 67 chronic chronic JJ cord-010398-5wot7tix 288 68 fatigue fatigue NN cord-010398-5wot7tix 288 69 in in IN cord-010398-5wot7tix 288 70 a a DT cord-010398-5wot7tix 288 71 population population NN cord-010398-5wot7tix 288 72 - - HYPH cord-010398-5wot7tix 288 73 based base VBN cord-010398-5wot7tix 288 74 sample sample NN cord-010398-5wot7tix 288 75 Epstein Epstein NNP cord-010398-5wot7tix 288 76 - - HYPH cord-010398-5wot7tix 288 77 Barr Barr NNP cord-010398-5wot7tix 288 78 virus virus NN cord-010398-5wot7tix 288 79 ( ( -LRB- cord-010398-5wot7tix 288 80 EBV EBV NNP cord-010398-5wot7tix 288 81 ) ) -RRB- cord-010398-5wot7tix 288 82 and and CC cord-010398-5wot7tix 288 83 the the DT cord-010398-5wot7tix 288 84 chronic chronic JJ cord-010398-5wot7tix 288 85 fatigue fatigue NN cord-010398-5wot7tix 288 86 syndrome syndrome NN cord-010398-5wot7tix 288 87 : : : cord-010398-5wot7tix 288 88 Normal normal JJ cord-010398-5wot7tix 288 89 virus virus NN cord-010398-5wot7tix 288 90 load load NN cord-010398-5wot7tix 288 91 in in IN cord-010398-5wot7tix 288 92 blood blood NN cord-010398-5wot7tix 288 93 and and CC cord-010398-5wot7tix 288 94 normal normal JJ cord-010398-5wot7tix 288 95 immunologic immunologic JJ cord-010398-5wot7tix 288 96 reactivity reactivity NN cord-010398-5wot7tix 288 97 in in IN cord-010398-5wot7tix 288 98 the the DT cord-010398-5wot7tix 288 99 EBV EBV NNP cord-010398-5wot7tix 288 100 regression regression NN cord-010398-5wot7tix 288 101 assay assay NN cord-010398-5wot7tix 289 1 Multiple multiple JJ cord-010398-5wot7tix 289 2 mycoplasmal mycoplasmal VBN cord-010398-5wot7tix 289 3 infections infection NNS cord-010398-5wot7tix 289 4 detected detect VBN cord-010398-5wot7tix 289 5 in in IN cord-010398-5wot7tix 289 6 blood blood NN cord-010398-5wot7tix 289 7 of of IN cord-010398-5wot7tix 289 8 patients patient NNS cord-010398-5wot7tix 289 9 with with IN cord-010398-5wot7tix 289 10 chronic chronic JJ cord-010398-5wot7tix 289 11 fatigue fatigue NN cord-010398-5wot7tix 289 12 syndrome syndrome NN cord-010398-5wot7tix 289 13 and/or and/or CC cord-010398-5wot7tix 289 14 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 289 15 syndrome syndrome NN cord-010398-5wot7tix 290 1 Doxycycline Doxycycline NNP cord-010398-5wot7tix 290 2 treatment treatment NN cord-010398-5wot7tix 290 3 and and CC cord-010398-5wot7tix 290 4 Desert Desert NNP cord-010398-5wot7tix 290 5 Storm Storm NNP cord-010398-5wot7tix 290 6 Chronic Chronic NNP cord-010398-5wot7tix 290 7 multisymptom multisymptom JJ cord-010398-5wot7tix 290 8 illness illness NN cord-010398-5wot7tix 290 9 affecting affect VBG cord-010398-5wot7tix 290 10 Air Air NNP cord-010398-5wot7tix 290 11 Force Force NNP cord-010398-5wot7tix 290 12 veterans veteran NNS cord-010398-5wot7tix 290 13 of of IN cord-010398-5wot7tix 290 14 the the DT cord-010398-5wot7tix 290 15 Gulf Gulf NNP cord-010398-5wot7tix 290 16 War War NNP cord-010398-5wot7tix 290 17 Deployment Deployment NNP cord-010398-5wot7tix 290 18 stressors stressor NNS cord-010398-5wot7tix 290 19 and and CC cord-010398-5wot7tix 290 20 a a DT cord-010398-5wot7tix 290 21 chronic chronic JJ cord-010398-5wot7tix 290 22 multisymptom multisymptom JJ cord-010398-5wot7tix 290 23 illness illness NN cord-010398-5wot7tix 290 24 among among IN cord-010398-5wot7tix 290 25 Gulf Gulf NNP cord-010398-5wot7tix 290 26 War War NNP cord-010398-5wot7tix 290 27 veterans veteran NNS cord-010398-5wot7tix 290 28 Epidemic Epidemic NNP cord-010398-5wot7tix 290 29 neuromyasthenia neuromyasthenia NN cord-010398-5wot7tix 290 30 and and CC cord-010398-5wot7tix 290 31 chronic chronic JJ cord-010398-5wot7tix 290 32 fatigue fatigue NN cord-010398-5wot7tix 290 33 syndrome syndrome NN cord-010398-5wot7tix 290 34 : : : cord-010398-5wot7tix 290 35 Epidemiological epidemiological JJ cord-010398-5wot7tix 290 36 importance importance NN cord-010398-5wot7tix 290 37 of of IN cord-010398-5wot7tix 290 38 a a DT cord-010398-5wot7tix 290 39 cluster cluster NN cord-010398-5wot7tix 290 40 definition definition NN cord-010398-5wot7tix 290 41 Chronic Chronic NNP cord-010398-5wot7tix 290 42 fatigue fatigue NN cord-010398-5wot7tix 290 43 syndrome syndrome NN cord-010398-5wot7tix 290 44 : : : cord-010398-5wot7tix 291 1 The the DT cord-010398-5wot7tix 291 2 need need NN cord-010398-5wot7tix 291 3 for for IN cord-010398-5wot7tix 291 4 subtypes subtype NNS cord-010398-5wot7tix 291 5 Replication replication NN cord-010398-5wot7tix 291 6 of of IN cord-010398-5wot7tix 291 7 an an DT cord-010398-5wot7tix 291 8 empirical empirical JJ cord-010398-5wot7tix 291 9 approach approach NN cord-010398-5wot7tix 291 10 to to TO cord-010398-5wot7tix 291 11 delineate delineate VB cord-010398-5wot7tix 291 12 the the DT cord-010398-5wot7tix 291 13 heterogeneity heterogeneity NN cord-010398-5wot7tix 291 14 of of IN cord-010398-5wot7tix 291 15 chronic chronic JJ cord-010398-5wot7tix 291 16 unexplained unexplained JJ cord-010398-5wot7tix 291 17 fatigue fatigue NN cord-010398-5wot7tix 292 1 The the DT cord-010398-5wot7tix 292 2 chronic chronic JJ cord-010398-5wot7tix 292 3 fatigue fatigue NN cord-010398-5wot7tix 292 4 syndrome syndrome NN cord-010398-5wot7tix 292 5 : : : cord-010398-5wot7tix 293 1 A a DT cord-010398-5wot7tix 293 2 comprehensive comprehensive JJ cord-010398-5wot7tix 293 3 approach approach NN cord-010398-5wot7tix 293 4 to to IN cord-010398-5wot7tix 293 5 its -PRON- PRP$ cord-010398-5wot7tix 293 6 definition definition NN cord-010398-5wot7tix 293 7 and and CC cord-010398-5wot7tix 293 8 study study NN cord-010398-5wot7tix 293 9 . . . cord-010398-5wot7tix 294 1 International International NNP cord-010398-5wot7tix 294 2 Chronic Chronic NNP cord-010398-5wot7tix 294 3 Fatigue Fatigue NNP cord-010398-5wot7tix 294 4 Syndrome Syndrome NNP cord-010398-5wot7tix 294 5 Study Study NNP cord-010398-5wot7tix 294 6 Group Group NNP cord-010398-5wot7tix 294 7 Prevalence Prevalence NNP cord-010398-5wot7tix 294 8 of of IN cord-010398-5wot7tix 294 9 chronic chronic JJ cord-010398-5wot7tix 294 10 fatigue fatigue NN cord-010398-5wot7tix 294 11 syndrome syndrome NN cord-010398-5wot7tix 294 12 in in IN cord-010398-5wot7tix 294 13 metropolitan metropolitan NNP cord-010398-5wot7tix 294 14 , , , cord-010398-5wot7tix 294 15 urban urban JJ cord-010398-5wot7tix 294 16 , , , cord-010398-5wot7tix 294 17 and and CC cord-010398-5wot7tix 294 18 rural rural JJ cord-010398-5wot7tix 294 19 Georgia Georgia NNP cord-010398-5wot7tix 295 1 The the DT cord-010398-5wot7tix 295 2 American American NNP cord-010398-5wot7tix 295 3 College College NNP cord-010398-5wot7tix 295 4 of of IN cord-010398-5wot7tix 295 5 Rheumatology Rheumatology NNP cord-010398-5wot7tix 295 6 1990 1990 CD cord-010398-5wot7tix 295 7 Criteria Criteria NNPS cord-010398-5wot7tix 295 8 for for IN cord-010398-5wot7tix 295 9 the the DT cord-010398-5wot7tix 295 10 Classification Classification NNP cord-010398-5wot7tix 295 11 of of IN cord-010398-5wot7tix 295 12 Fibromyalgia Fibromyalgia NNP cord-010398-5wot7tix 295 13 . . . cord-010398-5wot7tix 296 1 Report report NN cord-010398-5wot7tix 296 2 of of IN cord-010398-5wot7tix 296 3 the the DT cord-010398-5wot7tix 296 4 Multicenter Multicenter NNP cord-010398-5wot7tix 296 5 Criteria Criteria NNP cord-010398-5wot7tix 296 6 Committee Committee NNP cord-010398-5wot7tix 296 7 A a DT cord-010398-5wot7tix 296 8 review review NN cord-010398-5wot7tix 296 9 of of IN cord-010398-5wot7tix 296 10 the the DT cord-010398-5wot7tix 296 11 evidence evidence NN cord-010398-5wot7tix 296 12 for for IN cord-010398-5wot7tix 296 13 overlap overlap NN cord-010398-5wot7tix 296 14 among among IN cord-010398-5wot7tix 296 15 unexplained unexplained JJ cord-010398-5wot7tix 296 16 clinical clinical JJ cord-010398-5wot7tix 296 17 conditions condition NNS cord-010398-5wot7tix 297 1 Comorbid comorbid VB cord-010398-5wot7tix 297 2 clinical clinical JJ cord-010398-5wot7tix 297 3 conditions condition NNS cord-010398-5wot7tix 297 4 in in IN cord-010398-5wot7tix 297 5 chronic chronic JJ cord-010398-5wot7tix 297 6 fatigue fatigue NN cord-010398-5wot7tix 297 7 : : : cord-010398-5wot7tix 297 8 A a DT cord-010398-5wot7tix 297 9 co co JJ cord-010398-5wot7tix 297 10 - - JJ cord-010398-5wot7tix 297 11 twin twin JJ cord-010398-5wot7tix 297 12 control control NN cord-010398-5wot7tix 297 13 study study NN cord-010398-5wot7tix 297 14 Are be VBP cord-010398-5wot7tix 297 15 chronic chronic JJ cord-010398-5wot7tix 297 16 fatigue fatigue NN cord-010398-5wot7tix 297 17 and and CC cord-010398-5wot7tix 297 18 chronic chronic JJ cord-010398-5wot7tix 297 19 fatigue fatigue NN cord-010398-5wot7tix 297 20 syndrome syndrome NN cord-010398-5wot7tix 297 21 valid valid JJ cord-010398-5wot7tix 297 22 clinical clinical JJ cord-010398-5wot7tix 297 23 entities entity NNS cord-010398-5wot7tix 297 24 across across IN cord-010398-5wot7tix 297 25 countries country NNS cord-010398-5wot7tix 297 26 and and CC cord-010398-5wot7tix 297 27 health health NN cord-010398-5wot7tix 297 28 - - HYPH cord-010398-5wot7tix 297 29 care care NN cord-010398-5wot7tix 297 30 settings setting NNS cord-010398-5wot7tix 297 31 ? ? . cord-010398-5wot7tix 298 1 Comparative comparative JJ cord-010398-5wot7tix 298 2 epidemiology epidemiology NN cord-010398-5wot7tix 298 3 of of IN cord-010398-5wot7tix 298 4 chronic chronic JJ cord-010398-5wot7tix 298 5 fatigue fatigue NN cord-010398-5wot7tix 298 6 syndrome syndrome NN cord-010398-5wot7tix 298 7 in in IN cord-010398-5wot7tix 298 8 Brazilian brazilian JJ cord-010398-5wot7tix 298 9 and and CC cord-010398-5wot7tix 298 10 British british JJ cord-010398-5wot7tix 298 11 primary primary JJ cord-010398-5wot7tix 298 12 care care NN cord-010398-5wot7tix 298 13 : : : cord-010398-5wot7tix 299 1 Prevalence prevalence NN cord-010398-5wot7tix 299 2 and and CC cord-010398-5wot7tix 299 3 recognition recognition NN cord-010398-5wot7tix 300 1 The the DT cord-010398-5wot7tix 300 2 prevalence prevalence NN cord-010398-5wot7tix 300 3 of of IN cord-010398-5wot7tix 300 4 chronic chronic JJ cord-010398-5wot7tix 300 5 fatigue fatigue NN cord-010398-5wot7tix 300 6 syndrome syndrome NN cord-010398-5wot7tix 300 7 in in IN cord-010398-5wot7tix 300 8 Nigeria Nigeria NNP cord-010398-5wot7tix 300 9 Prevalence Prevalence NNP cord-010398-5wot7tix 300 10 of of IN cord-010398-5wot7tix 300 11 chronic chronic JJ cord-010398-5wot7tix 300 12 fatigue fatigue NN cord-010398-5wot7tix 300 13 and and CC cord-010398-5wot7tix 300 14 chronic chronic JJ cord-010398-5wot7tix 300 15 fatigue fatigue NN cord-010398-5wot7tix 300 16 syndrome syndrome NN cord-010398-5wot7tix 300 17 in in IN cord-010398-5wot7tix 300 18 Korea Korea NNP cord-010398-5wot7tix 300 19 : : : cord-010398-5wot7tix 300 20 Community community NN cord-010398-5wot7tix 300 21 - - HYPH cord-010398-5wot7tix 300 22 based base VBN cord-010398-5wot7tix 300 23 primary primary JJ cord-010398-5wot7tix 300 24 care care NN cord-010398-5wot7tix 300 25 study study NN cord-010398-5wot7tix 300 26 Fatigue Fatigue NNP cord-010398-5wot7tix 300 27 and and CC cord-010398-5wot7tix 300 28 chronic chronic JJ cord-010398-5wot7tix 300 29 fatigue fatigue NN cord-010398-5wot7tix 300 30 syndrome syndrome NN cord-010398-5wot7tix 300 31 - - HYPH cord-010398-5wot7tix 300 32 like like JJ cord-010398-5wot7tix 300 33 complaints complaint NNS cord-010398-5wot7tix 300 34 in in IN cord-010398-5wot7tix 300 35 the the DT cord-010398-5wot7tix 300 36 general general JJ cord-010398-5wot7tix 300 37 population population NN cord-010398-5wot7tix 300 38 Further further JJ cord-010398-5wot7tix 300 39 validation validation NN cord-010398-5wot7tix 300 40 of of IN cord-010398-5wot7tix 300 41 the the DT cord-010398-5wot7tix 300 42 Multidimensional Multidimensional NNP cord-010398-5wot7tix 300 43 Fatigue Fatigue NNP cord-010398-5wot7tix 300 44 Inventory Inventory NNP cord-010398-5wot7tix 300 45 in in IN cord-010398-5wot7tix 300 46 a a DT cord-010398-5wot7tix 300 47 US US NNP cord-010398-5wot7tix 300 48 adult adult NN cord-010398-5wot7tix 300 49 population population NN cord-010398-5wot7tix 300 50 sample sample NN cord-010398-5wot7tix 300 51 Perceived perceive VBN cord-010398-5wot7tix 300 52 exertion exertion NN cord-010398-5wot7tix 300 53 in in IN cord-010398-5wot7tix 300 54 fatiguing fatiguing JJ cord-010398-5wot7tix 300 55 illness illness NN cord-010398-5wot7tix 300 56 : : : cord-010398-5wot7tix 300 57 Civilians civilian NNS cord-010398-5wot7tix 300 58 with with IN cord-010398-5wot7tix 300 59 chronic chronic JJ cord-010398-5wot7tix 300 60 fatigue fatigue NN cord-010398-5wot7tix 300 61 syndrome syndrome NN cord-010398-5wot7tix 300 62 Physical physical JJ cord-010398-5wot7tix 300 63 fatigability fatigability NN cord-010398-5wot7tix 300 64 and and CC cord-010398-5wot7tix 300 65 exercise exercise NN cord-010398-5wot7tix 300 66 capacity capacity NN cord-010398-5wot7tix 300 67 in in IN cord-010398-5wot7tix 300 68 chronic chronic JJ cord-010398-5wot7tix 300 69 fatigue fatigue NN cord-010398-5wot7tix 300 70 syndrome syndrome NN cord-010398-5wot7tix 300 71 : : : cord-010398-5wot7tix 300 72 Association Association NNP cord-010398-5wot7tix 300 73 with with IN cord-010398-5wot7tix 300 74 disability disability NN cord-010398-5wot7tix 300 75 , , , cord-010398-5wot7tix 300 76 somatization somatization NN cord-010398-5wot7tix 300 77 and and CC cord-010398-5wot7tix 300 78 psychopathology psychopathology NN cord-010398-5wot7tix 300 79 Aerobic aerobic JJ cord-010398-5wot7tix 300 80 work work NN cord-010398-5wot7tix 300 81 capacity capacity NN cord-010398-5wot7tix 300 82 in in IN cord-010398-5wot7tix 300 83 patients patient NNS cord-010398-5wot7tix 300 84 with with IN cord-010398-5wot7tix 300 85 chronic chronic JJ cord-010398-5wot7tix 300 86 fatigue fatigue NN cord-010398-5wot7tix 300 87 syndrome syndrome NN cord-010398-5wot7tix 300 88 Exploratory exploratory JJ cord-010398-5wot7tix 300 89 analysis analysis NN cord-010398-5wot7tix 300 90 of of IN cord-010398-5wot7tix 300 91 the the DT cord-010398-5wot7tix 300 92 relationships relationship NNS cord-010398-5wot7tix 300 93 between between IN cord-010398-5wot7tix 300 94 aerobic aerobic JJ cord-010398-5wot7tix 300 95 capacity capacity NN cord-010398-5wot7tix 300 96 and and CC cord-010398-5wot7tix 300 97 self self NN cord-010398-5wot7tix 300 98 - - HYPH cord-010398-5wot7tix 300 99 reported report VBN cord-010398-5wot7tix 300 100 fatigue fatigue NN cord-010398-5wot7tix 300 101 in in IN cord-010398-5wot7tix 300 102 patients patient NNS cord-010398-5wot7tix 300 103 with with IN cord-010398-5wot7tix 300 104 rheumatoid rheumatoid NN cord-010398-5wot7tix 300 105 arthritis arthritis NN cord-010398-5wot7tix 300 106 , , , cord-010398-5wot7tix 300 107 polymyositis polymyositis NNP cord-010398-5wot7tix 300 108 , , , cord-010398-5wot7tix 300 109 and and CC cord-010398-5wot7tix 300 110 chronic chronic JJ cord-010398-5wot7tix 300 111 fatigue fatigue NN cord-010398-5wot7tix 300 112 syndrome syndrome NN cord-010398-5wot7tix 300 113 Effects effect NNS cord-010398-5wot7tix 300 114 of of IN cord-010398-5wot7tix 300 115 exercise exercise NN cord-010398-5wot7tix 300 116 on on IN cord-010398-5wot7tix 300 117 cognitive cognitive JJ cord-010398-5wot7tix 300 118 and and CC cord-010398-5wot7tix 300 119 motor motor NN cord-010398-5wot7tix 300 120 function function NN cord-010398-5wot7tix 300 121 in in IN cord-010398-5wot7tix 300 122 chronic chronic JJ cord-010398-5wot7tix 300 123 fatigue fatigue NN cord-010398-5wot7tix 300 124 syndrome syndrome NN cord-010398-5wot7tix 300 125 and and CC cord-010398-5wot7tix 301 1 depression depression NN cord-010398-5wot7tix 301 2 Diminished diminish VBD cord-010398-5wot7tix 301 3 central central JJ cord-010398-5wot7tix 301 4 activation activation NN cord-010398-5wot7tix 301 5 during during IN cord-010398-5wot7tix 301 6 maximal maximal JJ cord-010398-5wot7tix 301 7 voluntary voluntary JJ cord-010398-5wot7tix 301 8 contraction contraction NN cord-010398-5wot7tix 301 9 in in IN cord-010398-5wot7tix 301 10 chronic chronic JJ cord-010398-5wot7tix 301 11 fatigue fatigue NN cord-010398-5wot7tix 301 12 syndrome syndrome NN cord-010398-5wot7tix 301 13 Chronic Chronic NNP cord-010398-5wot7tix 301 14 fatigue fatigue NN cord-010398-5wot7tix 301 15 syndrome syndrome NN cord-010398-5wot7tix 301 16 : : : cord-010398-5wot7tix 302 1 New new JJ cord-010398-5wot7tix 302 2 evidence evidence NN cord-010398-5wot7tix 302 3 for for IN cord-010398-5wot7tix 302 4 a a DT cord-010398-5wot7tix 302 5 central central JJ cord-010398-5wot7tix 302 6 fatigue fatigue NN cord-010398-5wot7tix 302 7 disorder disorder NN cord-010398-5wot7tix 302 8 Primary primary JJ cord-010398-5wot7tix 302 9 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 302 10 syndrome syndrome NN cord-010398-5wot7tix 302 11 : : : cord-010398-5wot7tix 302 12 Current current JJ cord-010398-5wot7tix 302 13 concepts concept NNS cord-010398-5wot7tix 303 1 Central central JJ cord-010398-5wot7tix 303 2 sensitivity sensitivity NN cord-010398-5wot7tix 303 3 syndromes syndrome NNS cord-010398-5wot7tix 303 4 : : : cord-010398-5wot7tix 303 5 A a DT cord-010398-5wot7tix 303 6 new new JJ cord-010398-5wot7tix 303 7 paradigm paradigm NN cord-010398-5wot7tix 303 8 and and CC cord-010398-5wot7tix 303 9 group group NN cord-010398-5wot7tix 303 10 nosology nosology NN cord-010398-5wot7tix 303 11 for for IN cord-010398-5wot7tix 303 12 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 303 13 and and CC cord-010398-5wot7tix 303 14 overlapping overlapping JJ cord-010398-5wot7tix 303 15 conditions condition NNS cord-010398-5wot7tix 303 16 , , , cord-010398-5wot7tix 303 17 and and CC cord-010398-5wot7tix 303 18 the the DT cord-010398-5wot7tix 303 19 related related JJ cord-010398-5wot7tix 303 20 issue issue NN cord-010398-5wot7tix 303 21 of of IN cord-010398-5wot7tix 303 22 disease disease NN cord-010398-5wot7tix 303 23 versus versus IN cord-010398-5wot7tix 303 24 illness illness NN cord-010398-5wot7tix 303 25 Fibromyalgia Fibromyalgia NNP cord-010398-5wot7tix 303 26 and and CC cord-010398-5wot7tix 303 27 major major JJ cord-010398-5wot7tix 303 28 affective affective JJ cord-010398-5wot7tix 303 29 disorder disorder NN cord-010398-5wot7tix 303 30 : : : cord-010398-5wot7tix 304 1 A a DT cord-010398-5wot7tix 304 2 controlled control VBN cord-010398-5wot7tix 304 3 phenomenology phenomenology NN cord-010398-5wot7tix 304 4 and and CC cord-010398-5wot7tix 304 5 family family NN cord-010398-5wot7tix 304 6 history history NN cord-010398-5wot7tix 304 7 study study NN cord-010398-5wot7tix 304 8 Fibromyalgia Fibromyalgia NNP cord-010398-5wot7tix 304 9 and and CC cord-010398-5wot7tix 304 10 psychopathology psychopathology NN cord-010398-5wot7tix 305 1 : : : cord-010398-5wot7tix 305 2 Is be VBZ cord-010398-5wot7tix 305 3 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 305 4 a a DT cord-010398-5wot7tix 305 5 form form NN cord-010398-5wot7tix 305 6 of of IN cord-010398-5wot7tix 305 7 " " `` cord-010398-5wot7tix 305 8 affective affective JJ cord-010398-5wot7tix 305 9 spectrum spectrum NN cord-010398-5wot7tix 305 10 disorder disorder NN cord-010398-5wot7tix 305 11 Comorbidity comorbidity NN cord-010398-5wot7tix 305 12 of of IN cord-010398-5wot7tix 305 13 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 305 14 with with IN cord-010398-5wot7tix 305 15 medical medical JJ cord-010398-5wot7tix 305 16 and and CC cord-010398-5wot7tix 305 17 psychiatric psychiatric JJ cord-010398-5wot7tix 305 18 disorders disorder NNS cord-010398-5wot7tix 305 19 Psychiatric psychiatric JJ cord-010398-5wot7tix 305 20 diagnoses diagnosis NNS cord-010398-5wot7tix 305 21 in in IN cord-010398-5wot7tix 305 22 patients patient NNS cord-010398-5wot7tix 305 23 with with IN cord-010398-5wot7tix 305 24 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 305 25 are be VBP cord-010398-5wot7tix 305 26 related relate VBN cord-010398-5wot7tix 305 27 to to IN cord-010398-5wot7tix 305 28 health health NN cord-010398-5wot7tix 305 29 care care NN cord-010398-5wot7tix 305 30 - - HYPH cord-010398-5wot7tix 305 31 seeking seek VBG cord-010398-5wot7tix 305 32 behavior behavior NN cord-010398-5wot7tix 305 33 rather rather RB cord-010398-5wot7tix 305 34 than than IN cord-010398-5wot7tix 305 35 to to IN cord-010398-5wot7tix 305 36 illness illness NN cord-010398-5wot7tix 305 37 S. S. NNP cord-010398-5wot7tix 305 38 householder householder NN cord-010398-5wot7tix 305 39 survey survey NN cord-010398-5wot7tix 305 40 of of IN cord-010398-5wot7tix 305 41 functional functional JJ cord-010398-5wot7tix 305 42 gastrointestinal gastrointestinal JJ cord-010398-5wot7tix 305 43 disorders disorder NNS cord-010398-5wot7tix 305 44 : : : cord-010398-5wot7tix 305 45 Prevalence prevalence NN cord-010398-5wot7tix 305 46 , , , cord-010398-5wot7tix 305 47 sociodemography sociodemography NN cord-010398-5wot7tix 305 48 , , , cord-010398-5wot7tix 305 49 and and CC cord-010398-5wot7tix 305 50 health health NN cord-010398-5wot7tix 305 51 impact impact NN cord-010398-5wot7tix 306 1 A a DT cord-010398-5wot7tix 306 2 population population NN cord-010398-5wot7tix 306 3 - - HYPH cord-010398-5wot7tix 306 4 based base VBN cord-010398-5wot7tix 306 5 twin twin JJ cord-010398-5wot7tix 306 6 study study NN cord-010398-5wot7tix 306 7 of of IN cord-010398-5wot7tix 306 8 functional functional JJ cord-010398-5wot7tix 306 9 somatic somatic JJ cord-010398-5wot7tix 306 10 syndromes syndrome NNS cord-010398-5wot7tix 307 1 The the DT cord-010398-5wot7tix 307 2 genetics genetic NNS cord-010398-5wot7tix 307 3 of of IN cord-010398-5wot7tix 307 4 fibromyalgia fibromyalgia NNP cord-010398-5wot7tix 307 5 syndrome syndrome NNP cord-010398-5wot7tix 307 6 Family Family NNP cord-010398-5wot7tix 307 7 study study NN cord-010398-5wot7tix 307 8 of of IN cord-010398-5wot7tix 307 9 fibromyalgia fibromyalgia NNP cord-010398-5wot7tix 307 10 Self self NN cord-010398-5wot7tix 307 11 - - HYPH cord-010398-5wot7tix 307 12 reported report VBN cord-010398-5wot7tix 307 13 symptoms symptom NNS cord-010398-5wot7tix 307 14 before before IN cord-010398-5wot7tix 307 15 and and CC cord-010398-5wot7tix 307 16 after after IN cord-010398-5wot7tix 307 17 September September NNP cord-010398-5wot7tix 307 18 11 11 CD cord-010398-5wot7tix 307 19 in in IN cord-010398-5wot7tix 307 20 patients patient NNS cord-010398-5wot7tix 307 21 with with IN cord-010398-5wot7tix 307 22 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 307 23 A a DT cord-010398-5wot7tix 307 24 community community NN cord-010398-5wot7tix 307 25 - - HYPH cord-010398-5wot7tix 307 26 based base VBN cord-010398-5wot7tix 307 27 survey survey NN cord-010398-5wot7tix 307 28 of of IN cord-010398-5wot7tix 307 29 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 307 30 - - HYPH cord-010398-5wot7tix 307 31 like like JJ cord-010398-5wot7tix 307 32 pain pain NN cord-010398-5wot7tix 307 33 complaints complaint NNS cord-010398-5wot7tix 307 34 following follow VBG cord-010398-5wot7tix 307 35 the the DT cord-010398-5wot7tix 307 36 World World NNP cord-010398-5wot7tix 307 37 Trade Trade NNP cord-010398-5wot7tix 307 38 Center Center NNP cord-010398-5wot7tix 307 39 terrorist terrorist JJ cord-010398-5wot7tix 307 40 attacks attack NNS cord-010398-5wot7tix 307 41 Memory memory NN cord-010398-5wot7tix 307 42 , , , cord-010398-5wot7tix 307 43 attention attention NN cord-010398-5wot7tix 307 44 , , , cord-010398-5wot7tix 307 45 and and CC cord-010398-5wot7tix 307 46 executive executive JJ cord-010398-5wot7tix 307 47 function function NN cord-010398-5wot7tix 307 48 in in IN cord-010398-5wot7tix 307 49 chronic chronic JJ cord-010398-5wot7tix 307 50 fatigue fatigue NN cord-010398-5wot7tix 307 51 syndrome syndrome NN cord-010398-5wot7tix 308 1 A a DT cord-010398-5wot7tix 308 2 comparative comparative JJ cord-010398-5wot7tix 308 3 review review NN cord-010398-5wot7tix 308 4 of of IN cord-010398-5wot7tix 308 5 systemic systemic JJ cord-010398-5wot7tix 308 6 and and CC cord-010398-5wot7tix 308 7 neurological neurological JJ cord-010398-5wot7tix 308 8 symptomatology symptomatology NN cord-010398-5wot7tix 308 9 in in IN cord-010398-5wot7tix 308 10 12 12 CD cord-010398-5wot7tix 308 11 outbreaks outbreak NNS cord-010398-5wot7tix 308 12 collectively collectively RB cord-010398-5wot7tix 308 13 described describe VBN cord-010398-5wot7tix 308 14 as as IN cord-010398-5wot7tix 308 15 chronic chronic JJ cord-010398-5wot7tix 308 16 fatigue fatigue NN cord-010398-5wot7tix 308 17 syndrome syndrome NN cord-010398-5wot7tix 308 18 , , , cord-010398-5wot7tix 308 19 epidemic epidemic NN cord-010398-5wot7tix 308 20 neuromyasthenia neuromyasthenia NNP cord-010398-5wot7tix 308 21 , , , cord-010398-5wot7tix 308 22 and and CC cord-010398-5wot7tix 308 23 myalgic myalgic JJ cord-010398-5wot7tix 308 24 encephalomyelitis encephalomyelitis NN cord-010398-5wot7tix 308 25 Fixed fix VBN cord-010398-5wot7tix 308 26 belief belief NN cord-010398-5wot7tix 308 27 in in IN cord-010398-5wot7tix 308 28 cognitive cognitive JJ cord-010398-5wot7tix 308 29 dysfunction dysfunction NN cord-010398-5wot7tix 308 30 despite despite IN cord-010398-5wot7tix 308 31 normal normal JJ cord-010398-5wot7tix 308 32 neuropsychological neuropsychological JJ cord-010398-5wot7tix 308 33 scores score NNS cord-010398-5wot7tix 308 34 : : : cord-010398-5wot7tix 308 35 Neurocognitive Neurocognitive NNP cord-010398-5wot7tix 308 36 hypochondriasis hypochondriasis NN cord-010398-5wot7tix 308 37 ? ? . cord-010398-5wot7tix 309 1 The the DT cord-010398-5wot7tix 309 2 neuropsychological neuropsychological JJ cord-010398-5wot7tix 309 3 dimensions dimension NNS cord-010398-5wot7tix 309 4 of of IN cord-010398-5wot7tix 309 5 postinfectious postinfectious NNP cord-010398-5wot7tix 309 6 neuromyasthenia neuromyasthenia NNP cord-010398-5wot7tix 309 7 ( ( -LRB- cord-010398-5wot7tix 309 8 chronic chronic NNP cord-010398-5wot7tix 309 9 fatigue fatigue NN cord-010398-5wot7tix 309 10 syndrome syndrome NN cord-010398-5wot7tix 309 11 ) ) -RRB- cord-010398-5wot7tix 309 12 : : : cord-010398-5wot7tix 310 1 A a DT cord-010398-5wot7tix 310 2 preliminary preliminary JJ cord-010398-5wot7tix 310 3 report report NN cord-010398-5wot7tix 310 4 Relation relation NN cord-010398-5wot7tix 310 5 between between IN cord-010398-5wot7tix 310 6 neuropsychological neuropsychological JJ cord-010398-5wot7tix 310 7 impairment impairment NN cord-010398-5wot7tix 310 8 and and CC cord-010398-5wot7tix 310 9 functional functional JJ cord-010398-5wot7tix 310 10 disability disability NN cord-010398-5wot7tix 310 11 in in IN cord-010398-5wot7tix 310 12 patients patient NNS cord-010398-5wot7tix 310 13 with with IN cord-010398-5wot7tix 310 14 chronic chronic JJ cord-010398-5wot7tix 310 15 fatigue fatigue NN cord-010398-5wot7tix 310 16 syndrome syndrome NN cord-010398-5wot7tix 310 17 Information information NN cord-010398-5wot7tix 310 18 processing processing NN cord-010398-5wot7tix 310 19 efficiency efficiency NN cord-010398-5wot7tix 310 20 in in IN cord-010398-5wot7tix 310 21 chronic chronic JJ cord-010398-5wot7tix 310 22 fatigue fatigue NN cord-010398-5wot7tix 310 23 syndrome syndrome NN cord-010398-5wot7tix 310 24 and and CC cord-010398-5wot7tix 310 25 multiple multiple JJ cord-010398-5wot7tix 310 26 sclerosis sclerosis NN cord-010398-5wot7tix 310 27 Memory memory NN cord-010398-5wot7tix 310 28 and and CC cord-010398-5wot7tix 310 29 attention attention NN cord-010398-5wot7tix 310 30 problems problem NNS cord-010398-5wot7tix 310 31 in in IN cord-010398-5wot7tix 310 32 children child NNS cord-010398-5wot7tix 310 33 with with IN cord-010398-5wot7tix 310 34 chronic chronic JJ cord-010398-5wot7tix 310 35 fatigue fatigue NN cord-010398-5wot7tix 310 36 syndrome syndrome NN cord-010398-5wot7tix 310 37 or or CC cord-010398-5wot7tix 310 38 myalgic myalgic JJ cord-010398-5wot7tix 310 39 encephalopathy encephalopathy NN cord-010398-5wot7tix 311 1 Cognitive cognitive JJ cord-010398-5wot7tix 311 2 deficits deficit NNS cord-010398-5wot7tix 311 3 in in IN cord-010398-5wot7tix 311 4 patients patient NNS cord-010398-5wot7tix 311 5 suffering suffer VBG cord-010398-5wot7tix 311 6 from from IN cord-010398-5wot7tix 311 7 chronic chronic JJ cord-010398-5wot7tix 311 8 fatigue fatigue NN cord-010398-5wot7tix 311 9 syndrome syndrome NN cord-010398-5wot7tix 311 10 , , , cord-010398-5wot7tix 311 11 acute acute JJ cord-010398-5wot7tix 311 12 infective infective JJ cord-010398-5wot7tix 311 13 illness illness NN cord-010398-5wot7tix 311 14 or or CC cord-010398-5wot7tix 311 15 depression depression NN cord-010398-5wot7tix 311 16 Neuropsychological neuropsychological JJ cord-010398-5wot7tix 311 17 performance performance NN cord-010398-5wot7tix 311 18 in in IN cord-010398-5wot7tix 311 19 persons person NNS cord-010398-5wot7tix 311 20 with with IN cord-010398-5wot7tix 311 21 chronic chronic JJ cord-010398-5wot7tix 311 22 fatigue fatigue NN cord-010398-5wot7tix 311 23 syndrome syndrome NN cord-010398-5wot7tix 311 24 : : : cord-010398-5wot7tix 312 1 Results result NNS cord-010398-5wot7tix 312 2 from from IN cord-010398-5wot7tix 312 3 a a DT cord-010398-5wot7tix 312 4 population population NN cord-010398-5wot7tix 312 5 - - HYPH cord-010398-5wot7tix 312 6 based base VBN cord-010398-5wot7tix 312 7 study study NN cord-010398-5wot7tix 312 8 Psychomotor Psychomotor NNP cord-010398-5wot7tix 312 9 functioning function VBG cord-010398-5wot7tix 312 10 in in IN cord-010398-5wot7tix 312 11 chronic chronic JJ cord-010398-5wot7tix 312 12 fatigue fatigue NN cord-010398-5wot7tix 312 13 syndrome syndrome NN cord-010398-5wot7tix 312 14 and and CC cord-010398-5wot7tix 312 15 major major JJ cord-010398-5wot7tix 312 16 depressive depressive JJ cord-010398-5wot7tix 312 17 disorder disorder NN cord-010398-5wot7tix 312 18 : : : cord-010398-5wot7tix 313 1 A a DT cord-010398-5wot7tix 313 2 comparative comparative JJ cord-010398-5wot7tix 313 3 study study NN cord-010398-5wot7tix 313 4 Cognitive cognitive JJ cord-010398-5wot7tix 313 5 functioning functioning NN cord-010398-5wot7tix 313 6 and and CC cord-010398-5wot7tix 313 7 magnetic magnetic JJ cord-010398-5wot7tix 313 8 resonance resonance NN cord-010398-5wot7tix 313 9 imaging imaging NN cord-010398-5wot7tix 313 10 in in IN cord-010398-5wot7tix 313 11 chronic chronic JJ cord-010398-5wot7tix 313 12 fatigue fatigue NN cord-010398-5wot7tix 313 13 Brain Brain NNP cord-010398-5wot7tix 313 14 MR MR NNP cord-010398-5wot7tix 313 15 in in IN cord-010398-5wot7tix 313 16 chronic chronic JJ cord-010398-5wot7tix 313 17 fatigue fatigue NN cord-010398-5wot7tix 313 18 syndrome syndrome NN cord-010398-5wot7tix 313 19 A a DT cord-010398-5wot7tix 313 20 controlled control VBN cord-010398-5wot7tix 313 21 study study NN cord-010398-5wot7tix 313 22 of of IN cord-010398-5wot7tix 313 23 brain brain NN cord-010398-5wot7tix 313 24 magnetic magnetic JJ cord-010398-5wot7tix 313 25 resonance resonance NN cord-010398-5wot7tix 313 26 imaging imaging NN cord-010398-5wot7tix 313 27 in in IN cord-010398-5wot7tix 313 28 patients patient NNS cord-010398-5wot7tix 313 29 with with IN cord-010398-5wot7tix 313 30 the the DT cord-010398-5wot7tix 313 31 chronic chronic JJ cord-010398-5wot7tix 313 32 fatigue fatigue NN cord-010398-5wot7tix 313 33 syndrome syndrome NN cord-010398-5wot7tix 313 34 SPECT spect NN cord-010398-5wot7tix 313 35 imaging imaging NN cord-010398-5wot7tix 313 36 of of IN cord-010398-5wot7tix 313 37 the the DT cord-010398-5wot7tix 313 38 brain brain NN cord-010398-5wot7tix 313 39 : : : cord-010398-5wot7tix 314 1 Comparison comparison NN cord-010398-5wot7tix 314 2 of of IN cord-010398-5wot7tix 314 3 findings finding NNS cord-010398-5wot7tix 314 4 in in IN cord-010398-5wot7tix 314 5 patients patient NNS cord-010398-5wot7tix 314 6 with with IN cord-010398-5wot7tix 314 7 chronic chronic JJ cord-010398-5wot7tix 314 8 fatigue fatigue NN cord-010398-5wot7tix 314 9 syndrome syndrome NN cord-010398-5wot7tix 314 10 , , , cord-010398-5wot7tix 314 11 AIDS AIDS NNP cord-010398-5wot7tix 314 12 dementia dementia NN cord-010398-5wot7tix 314 13 complex complex NN cord-010398-5wot7tix 314 14 , , , cord-010398-5wot7tix 314 15 and and CC cord-010398-5wot7tix 314 16 major major JJ cord-010398-5wot7tix 314 17 unipolar unipolar JJ cord-010398-5wot7tix 314 18 depression depression NN cord-010398-5wot7tix 314 19 Brain Brain NNP cord-010398-5wot7tix 314 20 MRI MRI NNP cord-010398-5wot7tix 314 21 abnormalities abnormality NNS cord-010398-5wot7tix 314 22 exist exist VBP cord-010398-5wot7tix 314 23 in in IN cord-010398-5wot7tix 314 24 a a DT cord-010398-5wot7tix 314 25 subset subset NN cord-010398-5wot7tix 314 26 of of IN cord-010398-5wot7tix 314 27 patients patient NNS cord-010398-5wot7tix 314 28 with with IN cord-010398-5wot7tix 314 29 chronic chronic JJ cord-010398-5wot7tix 314 30 fatigue fatigue NN cord-010398-5wot7tix 314 31 syndrome syndrome NN cord-010398-5wot7tix 314 32 Increase increase NN cord-010398-5wot7tix 314 33 in in IN cord-010398-5wot7tix 314 34 prefrontal prefrontal JJ cord-010398-5wot7tix 314 35 cortical cortical JJ cord-010398-5wot7tix 314 36 volume volume NN cord-010398-5wot7tix 314 37 following follow VBG cord-010398-5wot7tix 314 38 cognitive cognitive JJ cord-010398-5wot7tix 314 39 behavioural behavioural JJ cord-010398-5wot7tix 314 40 therapy therapy NN cord-010398-5wot7tix 314 41 in in IN cord-010398-5wot7tix 314 42 patients patient NNS cord-010398-5wot7tix 314 43 with with IN cord-010398-5wot7tix 314 44 chronic chronic JJ cord-010398-5wot7tix 314 45 fatigue fatigue NN cord-010398-5wot7tix 314 46 syndrome syndrome NN cord-010398-5wot7tix 315 1 The the DT cord-010398-5wot7tix 315 2 neural neural JJ cord-010398-5wot7tix 315 3 correlates correlate NNS cord-010398-5wot7tix 315 4 of of IN cord-010398-5wot7tix 315 5 fatigue fatigue NN cord-010398-5wot7tix 315 6 : : : cord-010398-5wot7tix 315 7 An an DT cord-010398-5wot7tix 315 8 exploratory exploratory JJ cord-010398-5wot7tix 315 9 imaginal imaginal JJ cord-010398-5wot7tix 315 10 fatigue fatigue NN cord-010398-5wot7tix 315 11 provocation provocation NN cord-010398-5wot7tix 315 12 study study NN cord-010398-5wot7tix 315 13 in in IN cord-010398-5wot7tix 315 14 chronic chronic JJ cord-010398-5wot7tix 315 15 fatigue fatigue NN cord-010398-5wot7tix 315 16 syndrome syndrome NN cord-010398-5wot7tix 315 17 Sleep sleep NN cord-010398-5wot7tix 315 18 disorders disorder NNS cord-010398-5wot7tix 315 19 in in IN cord-010398-5wot7tix 315 20 patients patient NNS cord-010398-5wot7tix 315 21 with with IN cord-010398-5wot7tix 315 22 chronic chronic JJ cord-010398-5wot7tix 315 23 fatigue fatigue NN cord-010398-5wot7tix 315 24 Sleep sleep NN cord-010398-5wot7tix 315 25 anomalies anomaly NNS cord-010398-5wot7tix 315 26 in in IN cord-010398-5wot7tix 315 27 the the DT cord-010398-5wot7tix 315 28 chronic chronic JJ cord-010398-5wot7tix 315 29 fatigue fatigue NN cord-010398-5wot7tix 315 30 syndrome syndrome NN cord-010398-5wot7tix 315 31 . . . cord-010398-5wot7tix 316 1 A a DT cord-010398-5wot7tix 316 2 comorbidity comorbidity NN cord-010398-5wot7tix 316 3 study study NN cord-010398-5wot7tix 316 4 Sleep sleep NN cord-010398-5wot7tix 316 5 disturbance disturbance NN cord-010398-5wot7tix 316 6 in in IN cord-010398-5wot7tix 316 7 chronic chronic JJ cord-010398-5wot7tix 316 8 fatigue fatigue NN cord-010398-5wot7tix 316 9 syndrome syndrome NN cord-010398-5wot7tix 317 1 The the DT cord-010398-5wot7tix 317 2 significance significance NN cord-010398-5wot7tix 317 3 of of IN cord-010398-5wot7tix 317 4 the the DT cord-010398-5wot7tix 317 5 sleeping sleeping NN cord-010398-5wot7tix 317 6 - - HYPH cord-010398-5wot7tix 317 7 waking wake VBG cord-010398-5wot7tix 317 8 brain brain NN cord-010398-5wot7tix 317 9 for for IN cord-010398-5wot7tix 317 10 the the DT cord-010398-5wot7tix 317 11 understanding understanding NN cord-010398-5wot7tix 317 12 of of IN cord-010398-5wot7tix 317 13 widespread widespread JJ cord-010398-5wot7tix 317 14 musculoskeletal musculoskeletal JJ cord-010398-5wot7tix 317 15 pain pain NN cord-010398-5wot7tix 317 16 and and CC cord-010398-5wot7tix 317 17 fatigue fatigue NN cord-010398-5wot7tix 317 18 in in IN cord-010398-5wot7tix 317 19 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 317 20 syndrome syndrome NN cord-010398-5wot7tix 317 21 and and CC cord-010398-5wot7tix 317 22 allied ally VBN cord-010398-5wot7tix 317 23 syndromes syndrome NNS cord-010398-5wot7tix 317 24 Etiology etiology NN cord-010398-5wot7tix 317 25 of of IN cord-010398-5wot7tix 317 26 chronic chronic JJ cord-010398-5wot7tix 317 27 fatigue fatigue NN cord-010398-5wot7tix 317 28 syndrome syndrome NN cord-010398-5wot7tix 317 29 : : : cord-010398-5wot7tix 317 30 Testing test VBG cord-010398-5wot7tix 317 31 popular popular JJ cord-010398-5wot7tix 317 32 hypotheses hypothesis NNS cord-010398-5wot7tix 317 33 using use VBG cord-010398-5wot7tix 317 34 a a DT cord-010398-5wot7tix 317 35 national national JJ cord-010398-5wot7tix 317 36 birth birth NN cord-010398-5wot7tix 317 37 cohort cohort NN cord-010398-5wot7tix 317 38 study study VB cord-010398-5wot7tix 317 39 The the DT cord-010398-5wot7tix 317 40 effect effect NN cord-010398-5wot7tix 317 41 of of IN cord-010398-5wot7tix 317 42 brief brief JJ cord-010398-5wot7tix 317 43 exercise exercise NN cord-010398-5wot7tix 317 44 cessation cessation NN cord-010398-5wot7tix 317 45 on on IN cord-010398-5wot7tix 317 46 pain pain NN cord-010398-5wot7tix 317 47 , , , cord-010398-5wot7tix 317 48 fatigue fatigue NN cord-010398-5wot7tix 317 49 , , , cord-010398-5wot7tix 317 50 and and CC cord-010398-5wot7tix 317 51 mood mood NN cord-010398-5wot7tix 317 52 symptom symptom NN cord-010398-5wot7tix 317 53 development development NN cord-010398-5wot7tix 317 54 in in IN cord-010398-5wot7tix 317 55 healthy healthy JJ cord-010398-5wot7tix 317 56 , , , cord-010398-5wot7tix 317 57 fit fit JJ cord-010398-5wot7tix 317 58 individuals individual NNS cord-010398-5wot7tix 317 59 Pathophysiological Pathophysiological NNP cord-010398-5wot7tix 317 60 mechanisms mechanism NNS cord-010398-5wot7tix 317 61 in in IN cord-010398-5wot7tix 317 62 somatization somatization NN cord-010398-5wot7tix 317 63 Fatigue fatigue NN cord-010398-5wot7tix 317 64 and and CC cord-010398-5wot7tix 317 65 psychiatric psychiatric JJ cord-010398-5wot7tix 317 66 disorder disorder NN cord-010398-5wot7tix 317 67 : : : cord-010398-5wot7tix 318 1 Different different JJ cord-010398-5wot7tix 318 2 or or CC cord-010398-5wot7tix 318 3 the the DT cord-010398-5wot7tix 318 4 same same JJ cord-010398-5wot7tix 319 1 The the DT cord-010398-5wot7tix 319 2 relationship relationship NN cord-010398-5wot7tix 319 3 between between IN cord-010398-5wot7tix 319 4 prior prior JJ cord-010398-5wot7tix 319 5 psychiatric psychiatric JJ cord-010398-5wot7tix 319 6 disorder disorder NN cord-010398-5wot7tix 319 7 and and CC cord-010398-5wot7tix 319 8 chronic chronic JJ cord-010398-5wot7tix 319 9 fatigue fatigue NN cord-010398-5wot7tix 319 10 : : : cord-010398-5wot7tix 319 11 Evidence evidence NN cord-010398-5wot7tix 319 12 from from IN cord-010398-5wot7tix 319 13 a a DT cord-010398-5wot7tix 319 14 national national JJ cord-010398-5wot7tix 319 15 birth birth NN cord-010398-5wot7tix 319 16 cohort cohort NN cord-010398-5wot7tix 319 17 study study NN cord-010398-5wot7tix 319 18 Premorbid Premorbid NNP cord-010398-5wot7tix 319 19 personality personality NN cord-010398-5wot7tix 319 20 in in IN cord-010398-5wot7tix 319 21 chronic chronic JJ cord-010398-5wot7tix 319 22 fatigue fatigue NN cord-010398-5wot7tix 319 23 syndrome syndrome NN cord-010398-5wot7tix 319 24 as as IN cord-010398-5wot7tix 319 25 determined determine VBN cord-010398-5wot7tix 319 26 by by IN cord-010398-5wot7tix 319 27 the the DT cord-010398-5wot7tix 319 28 Temperament Temperament NNP cord-010398-5wot7tix 319 29 and and CC cord-010398-5wot7tix 319 30 Character Character NNP cord-010398-5wot7tix 319 31 Inventory Inventory NNP cord-010398-5wot7tix 320 1 Does do VBZ cord-010398-5wot7tix 320 2 depression depression NN cord-010398-5wot7tix 320 3 mediate mediate VB cord-010398-5wot7tix 320 4 the the DT cord-010398-5wot7tix 320 5 relation relation NN cord-010398-5wot7tix 320 6 between between IN cord-010398-5wot7tix 320 7 fatigue fatigue NN cord-010398-5wot7tix 320 8 severity severity NN cord-010398-5wot7tix 320 9 and and CC cord-010398-5wot7tix 320 10 disability disability NN cord-010398-5wot7tix 320 11 in in IN cord-010398-5wot7tix 320 12 chronic chronic JJ cord-010398-5wot7tix 320 13 fatigue fatigue NN cord-010398-5wot7tix 320 14 syndrome syndrome NN cord-010398-5wot7tix 320 15 sufferers sufferer NNS cord-010398-5wot7tix 320 16 ? ? . cord-010398-5wot7tix 321 1 Postinfectious Postinfectious NNP cord-010398-5wot7tix 321 2 chronic chronic JJ cord-010398-5wot7tix 321 3 fatigue fatigue NN cord-010398-5wot7tix 321 4 : : : cord-010398-5wot7tix 321 5 A a DT cord-010398-5wot7tix 321 6 distinct distinct JJ cord-010398-5wot7tix 321 7 syndrome syndrome NN cord-010398-5wot7tix 321 8 ? ? . cord-010398-5wot7tix 322 1 Neurocognitive neurocognitive JJ cord-010398-5wot7tix 322 2 and and CC cord-010398-5wot7tix 322 3 functional functional JJ cord-010398-5wot7tix 322 4 outcomes outcome NNS cord-010398-5wot7tix 322 5 in in IN cord-010398-5wot7tix 322 6 persons person NNS cord-010398-5wot7tix 322 7 recovering recover VBG cord-010398-5wot7tix 322 8 from from IN cord-010398-5wot7tix 322 9 West West NNP cord-010398-5wot7tix 322 10 Nile Nile NNP cord-010398-5wot7tix 322 11 virus virus NN cord-010398-5wot7tix 322 12 illness illness NN cord-010398-5wot7tix 322 13 Mental mental JJ cord-010398-5wot7tix 322 14 morbidities morbidity NNS cord-010398-5wot7tix 322 15 and and CC cord-010398-5wot7tix 322 16 chronic chronic JJ cord-010398-5wot7tix 322 17 fatigue fatigue NN cord-010398-5wot7tix 322 18 in in IN cord-010398-5wot7tix 322 19 severe severe JJ cord-010398-5wot7tix 322 20 acute acute JJ cord-010398-5wot7tix 322 21 respiratory respiratory JJ cord-010398-5wot7tix 322 22 syndrome syndrome NN cord-010398-5wot7tix 322 23 survivors survivor NNS cord-010398-5wot7tix 322 24 : : : cord-010398-5wot7tix 322 25 Long long JJ cord-010398-5wot7tix 322 26 - - HYPH cord-010398-5wot7tix 322 27 term term NN cord-010398-5wot7tix 322 28 follow follow NN cord-010398-5wot7tix 322 29 - - HYPH cord-010398-5wot7tix 322 30 up up NN cord-010398-5wot7tix 322 31 A a DT cord-010398-5wot7tix 322 32 case case NN cord-010398-5wot7tix 322 33 of of IN cord-010398-5wot7tix 322 34 Chronic Chronic NNP cord-010398-5wot7tix 322 35 Fatigue Fatigue NNP cord-010398-5wot7tix 322 36 Syndrome Syndrome NNP cord-010398-5wot7tix 322 37 following follow VBG cord-010398-5wot7tix 322 38 H1N1 H1N1 NNP cord-010398-5wot7tix 322 39 influenza influenza NN cord-010398-5wot7tix 322 40 ( ( -LRB- cord-010398-5wot7tix 322 41 swine swine NN cord-010398-5wot7tix 322 42 influenza influenza NN cord-010398-5wot7tix 322 43 ) ) -RRB- cord-010398-5wot7tix 323 1 Post post JJ cord-010398-5wot7tix 323 2 - - JJ cord-010398-5wot7tix 323 3 infective infective JJ cord-010398-5wot7tix 323 4 and and CC cord-010398-5wot7tix 323 5 chronic chronic JJ cord-010398-5wot7tix 323 6 fatigue fatigue NN cord-010398-5wot7tix 323 7 syndromes syndrome NNS cord-010398-5wot7tix 323 8 precipitated precipitate VBN cord-010398-5wot7tix 323 9 by by IN cord-010398-5wot7tix 323 10 viral viral JJ cord-010398-5wot7tix 323 11 and and CC cord-010398-5wot7tix 323 12 non non JJ cord-010398-5wot7tix 323 13 - - JJ cord-010398-5wot7tix 323 14 viral viral JJ cord-010398-5wot7tix 323 15 pathogens pathogen NNS cord-010398-5wot7tix 323 16 : : : cord-010398-5wot7tix 323 17 Prospective prospective JJ cord-010398-5wot7tix 323 18 cohort cohort NN cord-010398-5wot7tix 323 19 study study NN cord-010398-5wot7tix 323 20 Postinfective Postinfective NNP cord-010398-5wot7tix 323 21 fatigue fatigue NN cord-010398-5wot7tix 323 22 syndrome syndrome NN cord-010398-5wot7tix 323 23 is be VBZ cord-010398-5wot7tix 323 24 not not RB cord-010398-5wot7tix 323 25 associated associate VBN cord-010398-5wot7tix 323 26 with with IN cord-010398-5wot7tix 323 27 altered altered JJ cord-010398-5wot7tix 323 28 cytokine cytokine NN cord-010398-5wot7tix 323 29 production production NN cord-010398-5wot7tix 323 30 Postinfectious Postinfectious NNP cord-010398-5wot7tix 323 31 irritable irritable JJ cord-010398-5wot7tix 323 32 bowel bowel NN cord-010398-5wot7tix 323 33 syndrome syndrome NN cord-010398-5wot7tix 323 34 - - : cord-010398-5wot7tix 323 35 a a DT cord-010398-5wot7tix 323 36 meta meta JJ cord-010398-5wot7tix 323 37 - - HYPH cord-010398-5wot7tix 323 38 analysis analysis NN cord-010398-5wot7tix 323 39 Risk risk NN cord-010398-5wot7tix 323 40 markers marker NNS cord-010398-5wot7tix 323 41 for for IN cord-010398-5wot7tix 323 42 both both DT cord-010398-5wot7tix 323 43 chronic chronic JJ cord-010398-5wot7tix 323 44 fatigue fatigue NN cord-010398-5wot7tix 323 45 and and CC cord-010398-5wot7tix 323 46 irritable irritable JJ cord-010398-5wot7tix 323 47 bowel bowel NN cord-010398-5wot7tix 323 48 syndromes syndrome NNS cord-010398-5wot7tix 323 49 : : : cord-010398-5wot7tix 323 50 A a DT cord-010398-5wot7tix 323 51 prospective prospective JJ cord-010398-5wot7tix 323 52 case case NN cord-010398-5wot7tix 323 53 - - HYPH cord-010398-5wot7tix 323 54 control control NN cord-010398-5wot7tix 323 55 study study NN cord-010398-5wot7tix 323 56 in in IN cord-010398-5wot7tix 323 57 primary primary JJ cord-010398-5wot7tix 323 58 care care NN cord-010398-5wot7tix 323 59 Detection detection NN cord-010398-5wot7tix 323 60 of of IN cord-010398-5wot7tix 323 61 an an DT cord-010398-5wot7tix 323 62 infectious infectious JJ cord-010398-5wot7tix 323 63 retrovirus retrovirus NN cord-010398-5wot7tix 323 64 , , , cord-010398-5wot7tix 323 65 XMRV XMRV NNP cord-010398-5wot7tix 323 66 , , , cord-010398-5wot7tix 323 67 in in IN cord-010398-5wot7tix 323 68 blood blood NN cord-010398-5wot7tix 323 69 cells cell NNS cord-010398-5wot7tix 323 70 of of IN cord-010398-5wot7tix 323 71 patients patient NNS cord-010398-5wot7tix 323 72 with with IN cord-010398-5wot7tix 323 73 chronic chronic JJ cord-010398-5wot7tix 323 74 fatigue fatigue NN cord-010398-5wot7tix 323 75 syndrome syndrome NN cord-010398-5wot7tix 323 76 Psychosocial psychosocial JJ cord-010398-5wot7tix 323 77 correlates correlate NNS cord-010398-5wot7tix 323 78 of of IN cord-010398-5wot7tix 323 79 illness illness NN cord-010398-5wot7tix 323 80 burden burden NN cord-010398-5wot7tix 323 81 in in IN cord-010398-5wot7tix 323 82 chronic chronic JJ cord-010398-5wot7tix 323 83 fatigue fatigue NN cord-010398-5wot7tix 323 84 syndrome syndrome NN cord-010398-5wot7tix 323 85 Gene Gene NNP cord-010398-5wot7tix 323 86 expression expression NN cord-010398-5wot7tix 323 87 in in IN cord-010398-5wot7tix 323 88 peripheral peripheral JJ cord-010398-5wot7tix 323 89 blood blood NN cord-010398-5wot7tix 323 90 leukocytes leukocyte NNS cord-010398-5wot7tix 323 91 in in IN cord-010398-5wot7tix 323 92 monozygotic monozygotic JJ cord-010398-5wot7tix 323 93 twins twin NNS cord-010398-5wot7tix 323 94 discordant discordant JJ cord-010398-5wot7tix 323 95 for for IN cord-010398-5wot7tix 323 96 chronic chronic JJ cord-010398-5wot7tix 323 97 fatigue fatigue NN cord-010398-5wot7tix 323 98 : : : cord-010398-5wot7tix 323 99 No no DT cord-010398-5wot7tix 323 100 evidence evidence NN cord-010398-5wot7tix 323 101 of of IN cord-010398-5wot7tix 323 102 a a DT cord-010398-5wot7tix 323 103 biomarker biomarker NN cord-010398-5wot7tix 323 104 Aspects aspect NNS cord-010398-5wot7tix 323 105 of of IN cord-010398-5wot7tix 323 106 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 323 107 in in IN cord-010398-5wot7tix 323 108 the the DT cord-010398-5wot7tix 323 109 general general JJ cord-010398-5wot7tix 323 110 population population NN cord-010398-5wot7tix 323 111 : : : cord-010398-5wot7tix 323 112 Sex sex NN cord-010398-5wot7tix 323 113 , , , cord-010398-5wot7tix 323 114 pain pain NN cord-010398-5wot7tix 323 115 threshold threshold NN cord-010398-5wot7tix 323 116 , , , cord-010398-5wot7tix 323 117 and and CC cord-010398-5wot7tix 323 118 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 323 119 symptoms symptom NNS cord-010398-5wot7tix 324 1 The the DT cord-010398-5wot7tix 324 2 relation relation NN cord-010398-5wot7tix 324 3 between between IN cord-010398-5wot7tix 324 4 tender tender NN cord-010398-5wot7tix 324 5 points point NNS cord-010398-5wot7tix 324 6 and and CC cord-010398-5wot7tix 324 7 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 324 8 symptom symptom NN cord-010398-5wot7tix 324 9 variables variable NNS cord-010398-5wot7tix 324 10 : : : cord-010398-5wot7tix 324 11 Evidence evidence NN cord-010398-5wot7tix 324 12 that that IN cord-010398-5wot7tix 324 13 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 324 14 is be VBZ cord-010398-5wot7tix 324 15 not not RB cord-010398-5wot7tix 324 16 a a DT cord-010398-5wot7tix 324 17 discrete discrete JJ cord-010398-5wot7tix 324 18 disorder disorder NN cord-010398-5wot7tix 324 19 in in IN cord-010398-5wot7tix 324 20 the the DT cord-010398-5wot7tix 324 21 clinic clinic NN cord-010398-5wot7tix 324 22 Evoked evoke VBD cord-010398-5wot7tix 324 23 pain pain NN cord-010398-5wot7tix 324 24 measures measure NNS cord-010398-5wot7tix 324 25 in in IN cord-010398-5wot7tix 324 26 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 324 27 Pain pain NN cord-010398-5wot7tix 324 28 sensitivity sensitivity NN cord-010398-5wot7tix 324 29 in in IN cord-010398-5wot7tix 324 30 patients patient NNS cord-010398-5wot7tix 324 31 with with IN cord-010398-5wot7tix 324 32 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 324 33 ( ( -LRB- cord-010398-5wot7tix 324 34 FM FM NNP cord-010398-5wot7tix 324 35 ) ) -RRB- cord-010398-5wot7tix 324 36 : : : cord-010398-5wot7tix 325 1 Expectancy expectancy NN cord-010398-5wot7tix 325 2 effects effect NNS cord-010398-5wot7tix 325 3 on on IN cord-010398-5wot7tix 325 4 pain pain NN cord-010398-5wot7tix 325 5 measurements measurement NNS cord-010398-5wot7tix 325 6 Dolorimetry Dolorimetry NNP cord-010398-5wot7tix 325 7 performed perform VBD cord-010398-5wot7tix 325 8 at at IN cord-010398-5wot7tix 325 9 3 3 CD cord-010398-5wot7tix 325 10 paired pair VBD cord-010398-5wot7tix 325 11 tender tender NN cord-010398-5wot7tix 325 12 points point NNS cord-010398-5wot7tix 325 13 highly highly RB cord-010398-5wot7tix 325 14 predicts predict VBZ cord-010398-5wot7tix 325 15 overall overall JJ cord-010398-5wot7tix 325 16 tenderness tenderness NN cord-010398-5wot7tix 325 17 Increased increase VBN cord-010398-5wot7tix 325 18 pain pain NN cord-010398-5wot7tix 325 19 sensitivity sensitivity NN cord-010398-5wot7tix 325 20 in in IN cord-010398-5wot7tix 325 21 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 325 22 : : : cord-010398-5wot7tix 325 23 Effects effect NNS cord-010398-5wot7tix 325 24 of of IN cord-010398-5wot7tix 325 25 stimulus stimulus NN cord-010398-5wot7tix 325 26 type type NN cord-010398-5wot7tix 325 27 and and CC cord-010398-5wot7tix 325 28 mode mode NN cord-010398-5wot7tix 325 29 of of IN cord-010398-5wot7tix 325 30 presentation presentation NN cord-010398-5wot7tix 325 31 Dolorimetry Dolorimetry NNP cord-010398-5wot7tix 325 32 performed perform VBD cord-010398-5wot7tix 325 33 at at IN cord-010398-5wot7tix 325 34 3 3 CD cord-010398-5wot7tix 325 35 paired pair VBD cord-010398-5wot7tix 325 36 tender tender NN cord-010398-5wot7tix 325 37 points point NNS cord-010398-5wot7tix 325 38 highly highly RB cord-010398-5wot7tix 325 39 predicts predict VBZ cord-010398-5wot7tix 325 40 overall overall JJ cord-010398-5wot7tix 325 41 tenderness tenderness NN cord-010398-5wot7tix 325 42 Altered alter VBN cord-010398-5wot7tix 325 43 heat heat NN cord-010398-5wot7tix 325 44 pain pain NN cord-010398-5wot7tix 325 45 thresholds threshold NNS cord-010398-5wot7tix 325 46 and and CC cord-010398-5wot7tix 325 47 cerebral cerebral JJ cord-010398-5wot7tix 325 48 event event NN cord-010398-5wot7tix 325 49 - - HYPH cord-010398-5wot7tix 325 50 related relate VBN cord-010398-5wot7tix 325 51 potentials potential NNS cord-010398-5wot7tix 325 52 following follow VBG cord-010398-5wot7tix 325 53 painful painful JJ cord-010398-5wot7tix 325 54 CO2 co2 NN cord-010398-5wot7tix 325 55 laser laser NN cord-010398-5wot7tix 325 56 stimulation stimulation NN cord-010398-5wot7tix 325 57 in in IN cord-010398-5wot7tix 325 58 subjects subject NNS cord-010398-5wot7tix 325 59 with with IN cord-010398-5wot7tix 325 60 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 325 61 syndrome syndrome NN cord-010398-5wot7tix 325 62 Modulatory modulatory JJ cord-010398-5wot7tix 325 63 influence influence NN cord-010398-5wot7tix 325 64 on on IN cord-010398-5wot7tix 325 65 somatosensory somatosensory JJ cord-010398-5wot7tix 325 66 perception perception NN cord-010398-5wot7tix 325 67 from from IN cord-010398-5wot7tix 325 68 vibration vibration NN cord-010398-5wot7tix 325 69 and and CC cord-010398-5wot7tix 325 70 heterotopic heterotopic NNP cord-010398-5wot7tix 325 71 noxious noxious JJ cord-010398-5wot7tix 325 72 conditioning conditioning NN cord-010398-5wot7tix 325 73 stimulation stimulation NN cord-010398-5wot7tix 325 74 ( ( -LRB- cord-010398-5wot7tix 325 75 HNCS HNCS NNP cord-010398-5wot7tix 325 76 ) ) -RRB- cord-010398-5wot7tix 325 77 in in IN cord-010398-5wot7tix 325 78 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 325 79 patients patient NNS cord-010398-5wot7tix 325 80 and and CC cord-010398-5wot7tix 325 81 healthy healthy JJ cord-010398-5wot7tix 325 82 subjects subject NNS cord-010398-5wot7tix 325 83 Perception perception NN cord-010398-5wot7tix 325 84 of of IN cord-010398-5wot7tix 325 85 noxious noxious JJ cord-010398-5wot7tix 325 86 and and CC cord-010398-5wot7tix 325 87 innocuous innocuous JJ cord-010398-5wot7tix 325 88 heat heat NN cord-010398-5wot7tix 325 89 stimulation stimulation NN cord-010398-5wot7tix 325 90 among among IN cord-010398-5wot7tix 325 91 healthy healthy JJ cord-010398-5wot7tix 325 92 women woman NNS cord-010398-5wot7tix 325 93 and and CC cord-010398-5wot7tix 325 94 women woman NNS cord-010398-5wot7tix 325 95 with with IN cord-010398-5wot7tix 325 96 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 325 97 : : : cord-010398-5wot7tix 326 1 Association Association NNP cord-010398-5wot7tix 326 2 with with IN cord-010398-5wot7tix 326 3 mood mood NN cord-010398-5wot7tix 326 4 , , , cord-010398-5wot7tix 326 5 somatic somatic JJ cord-010398-5wot7tix 326 6 focus focus NN cord-010398-5wot7tix 326 7 , , , cord-010398-5wot7tix 326 8 and and CC cord-010398-5wot7tix 326 9 catastrophizing catastrophize VBG cord-010398-5wot7tix 326 10 Sensory sensory JJ cord-010398-5wot7tix 326 11 dysfunction dysfunction NN cord-010398-5wot7tix 326 12 in in IN cord-010398-5wot7tix 326 13 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 326 14 patients patient NNS cord-010398-5wot7tix 326 15 with with IN cord-010398-5wot7tix 326 16 implications implication NNS cord-010398-5wot7tix 326 17 for for IN cord-010398-5wot7tix 326 18 pathogenic pathogenic JJ cord-010398-5wot7tix 326 19 mechanisms mechanism NNS cord-010398-5wot7tix 326 20 Abnormal abnormal JJ cord-010398-5wot7tix 326 21 responses response NNS cord-010398-5wot7tix 326 22 to to IN cord-010398-5wot7tix 326 23 electrocutaneous electrocutaneous JJ cord-010398-5wot7tix 326 24 stimulation stimulation NN cord-010398-5wot7tix 326 25 in in IN cord-010398-5wot7tix 326 26 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 326 27 Quantitative quantitative JJ cord-010398-5wot7tix 326 28 sensory sensory JJ cord-010398-5wot7tix 326 29 testing testing NN cord-010398-5wot7tix 326 30 in in IN cord-010398-5wot7tix 326 31 vulvodynia vulvodynia NN cord-010398-5wot7tix 326 32 patients patient NNS cord-010398-5wot7tix 326 33 and and CC cord-010398-5wot7tix 326 34 increased increase VBD cord-010398-5wot7tix 326 35 peripheral peripheral JJ cord-010398-5wot7tix 326 36 pressure pressure NN cord-010398-5wot7tix 326 37 pain pain NN cord-010398-5wot7tix 326 38 sensitivity sensitivity NN cord-010398-5wot7tix 326 39 Sensitivity sensitivity NN cord-010398-5wot7tix 326 40 of of IN cord-010398-5wot7tix 326 41 patients patient NNS cord-010398-5wot7tix 326 42 with with IN cord-010398-5wot7tix 326 43 painful painful JJ cord-010398-5wot7tix 326 44 temporomandibular temporomandibular NN cord-010398-5wot7tix 326 45 disorders disorder NNS cord-010398-5wot7tix 326 46 to to TO cord-010398-5wot7tix 326 47 experimentally experimentally RB cord-010398-5wot7tix 326 48 evoked evoke VBN cord-010398-5wot7tix 326 49 pain pain NN cord-010398-5wot7tix 327 1 The the DT cord-010398-5wot7tix 327 2 relationship relationship NN cord-010398-5wot7tix 327 3 between between IN cord-010398-5wot7tix 327 4 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 327 5 and and CC cord-010398-5wot7tix 327 6 interstitial interstitial JJ cord-010398-5wot7tix 327 7 cystitis cystitis NNP cord-010398-5wot7tix 327 8 Psychophysical Psychophysical NNP cord-010398-5wot7tix 327 9 evidence evidence NN cord-010398-5wot7tix 327 10 of of IN cord-010398-5wot7tix 327 11 hypersensitivity hypersensitivity NN cord-010398-5wot7tix 327 12 in in IN cord-010398-5wot7tix 327 13 subjects subject NNS cord-010398-5wot7tix 327 14 with with IN cord-010398-5wot7tix 327 15 interstitial interstitial JJ cord-010398-5wot7tix 327 16 cystitis cystitis NN cord-010398-5wot7tix 327 17 Diffuse diffuse VB cord-010398-5wot7tix 327 18 noxious noxious JJ cord-010398-5wot7tix 327 19 inhibitory inhibitory JJ cord-010398-5wot7tix 327 20 control control NN cord-010398-5wot7tix 327 21 is be VBZ cord-010398-5wot7tix 327 22 delayed delay VBN cord-010398-5wot7tix 327 23 in in IN cord-010398-5wot7tix 327 24 chronic chronic JJ cord-010398-5wot7tix 327 25 fatigue fatigue NN cord-010398-5wot7tix 327 26 syndrome syndrome NN cord-010398-5wot7tix 327 27 : : : cord-010398-5wot7tix 328 1 An an DT cord-010398-5wot7tix 328 2 experimental experimental JJ cord-010398-5wot7tix 328 3 study study NN cord-010398-5wot7tix 328 4 Functional functional JJ cord-010398-5wot7tix 328 5 magnetic magnetic JJ cord-010398-5wot7tix 328 6 resonance resonance NN cord-010398-5wot7tix 328 7 imaging image VBG cord-010398-5wot7tix 328 8 evidence evidence NN cord-010398-5wot7tix 328 9 of of IN cord-010398-5wot7tix 328 10 augmented augment VBN cord-010398-5wot7tix 328 11 pain pain NN cord-010398-5wot7tix 328 12 processing processing NN cord-010398-5wot7tix 328 13 in in IN cord-010398-5wot7tix 328 14 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 328 15 Cerebral cerebral JJ cord-010398-5wot7tix 328 16 activation activation NN cord-010398-5wot7tix 328 17 in in IN cord-010398-5wot7tix 328 18 patients patient NNS cord-010398-5wot7tix 328 19 with with IN cord-010398-5wot7tix 328 20 irritable irritable JJ cord-010398-5wot7tix 328 21 bowel bowel NN cord-010398-5wot7tix 328 22 syndrome syndrome NN cord-010398-5wot7tix 328 23 and and CC cord-010398-5wot7tix 328 24 control control NN cord-010398-5wot7tix 328 25 subjects subject NNS cord-010398-5wot7tix 328 26 during during IN cord-010398-5wot7tix 328 27 rectosigmoid rectosigmoid JJ cord-010398-5wot7tix 328 28 stimulation stimulation NN cord-010398-5wot7tix 328 29 Evidence evidence NN cord-010398-5wot7tix 328 30 of of IN cord-010398-5wot7tix 328 31 augmented augment VBN cord-010398-5wot7tix 328 32 central central JJ cord-010398-5wot7tix 328 33 pain pain NN cord-010398-5wot7tix 328 34 processing processing NN cord-010398-5wot7tix 328 35 in in IN cord-010398-5wot7tix 328 36 idiopathic idiopathic JJ cord-010398-5wot7tix 328 37 chronic chronic JJ cord-010398-5wot7tix 328 38 low low JJ cord-010398-5wot7tix 328 39 back back JJ cord-010398-5wot7tix 328 40 pain pain NN cord-010398-5wot7tix 328 41 Hearing hearing NN cord-010398-5wot7tix 328 42 and and CC cord-010398-5wot7tix 328 43 vestibular vestibular JJ cord-010398-5wot7tix 328 44 abnormalities abnormality NNS cord-010398-5wot7tix 328 45 in in IN cord-010398-5wot7tix 328 46 primary primary JJ cord-010398-5wot7tix 328 47 fibrositis fibrositis NN cord-010398-5wot7tix 328 48 syndrome syndrome NN cord-010398-5wot7tix 329 1 Perceived perceive VBN cord-010398-5wot7tix 329 2 intensity intensity NN cord-010398-5wot7tix 329 3 and and CC cord-010398-5wot7tix 329 4 unpleasantness unpleasantness NN cord-010398-5wot7tix 329 5 of of IN cord-010398-5wot7tix 329 6 cutaneous cutaneous JJ cord-010398-5wot7tix 329 7 and and CC cord-010398-5wot7tix 329 8 auditory auditory JJ cord-010398-5wot7tix 329 9 stimuli stimulus NNS cord-010398-5wot7tix 329 10 : : : cord-010398-5wot7tix 329 11 An an DT cord-010398-5wot7tix 329 12 evaluation evaluation NN cord-010398-5wot7tix 329 13 of of IN cord-010398-5wot7tix 329 14 the the DT cord-010398-5wot7tix 329 15 generalized generalized JJ cord-010398-5wot7tix 329 16 hypervigilance hypervigilance NN cord-010398-5wot7tix 329 17 hypothesis hypothesis NN cord-010398-5wot7tix 330 1 The the DT cord-010398-5wot7tix 330 2 association association NN cord-010398-5wot7tix 330 3 between between IN cord-010398-5wot7tix 330 4 experimental experimental JJ cord-010398-5wot7tix 330 5 and and CC cord-010398-5wot7tix 330 6 clinical clinical JJ cord-010398-5wot7tix 330 7 pain pain NN cord-010398-5wot7tix 330 8 measures measure NNS cord-010398-5wot7tix 330 9 among among IN cord-010398-5wot7tix 330 10 persons person NNS cord-010398-5wot7tix 330 11 with with IN cord-010398-5wot7tix 330 12 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 330 13 and and CC cord-010398-5wot7tix 330 14 chronic chronic JJ cord-010398-5wot7tix 330 15 fatigue fatigue NN cord-010398-5wot7tix 330 16 syndrome syndrome NN cord-010398-5wot7tix 330 17 Comorbid Comorbid NNP cord-010398-5wot7tix 330 18 somatic somatic JJ cord-010398-5wot7tix 330 19 symptoms symptom NNS cord-010398-5wot7tix 330 20 and and CC cord-010398-5wot7tix 330 21 functional functional JJ cord-010398-5wot7tix 330 22 status status NN cord-010398-5wot7tix 330 23 in in IN cord-010398-5wot7tix 330 24 patients patient NNS cord-010398-5wot7tix 330 25 with with IN cord-010398-5wot7tix 330 26 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 330 27 and and CC cord-010398-5wot7tix 330 28 chronic chronic JJ cord-010398-5wot7tix 330 29 fatigue fatigue NN cord-010398-5wot7tix 330 30 syndrome syndrome NN cord-010398-5wot7tix 330 31 : : : cord-010398-5wot7tix 330 32 Sensory sensory JJ cord-010398-5wot7tix 330 33 amplification amplification NN cord-010398-5wot7tix 330 34 as as IN cord-010398-5wot7tix 330 35 a a DT cord-010398-5wot7tix 330 36 common common JJ cord-010398-5wot7tix 330 37 mechanism mechanism NN cord-010398-5wot7tix 331 1 The the DT cord-010398-5wot7tix 331 2 cerebral cerebral JJ cord-010398-5wot7tix 331 3 signature signature NN cord-010398-5wot7tix 331 4 for for IN cord-010398-5wot7tix 331 5 pain pain NN cord-010398-5wot7tix 331 6 perception perception NN cord-010398-5wot7tix 331 7 and and CC cord-010398-5wot7tix 331 8 its -PRON- PRP$ cord-010398-5wot7tix 331 9 modulation modulation NN cord-010398-5wot7tix 331 10 Human Human NNP cord-010398-5wot7tix 331 11 feelings feeling NNS cord-010398-5wot7tix 332 1 : : : cord-010398-5wot7tix 332 2 Why why WRB cord-010398-5wot7tix 332 3 are be VBP cord-010398-5wot7tix 332 4 some some DT cord-010398-5wot7tix 332 5 more more RBR cord-010398-5wot7tix 332 6 aware aware JJ cord-010398-5wot7tix 332 7 than than IN cord-010398-5wot7tix 332 8 others other NNS cord-010398-5wot7tix 332 9 ? ? . cord-010398-5wot7tix 333 1 Interoception interoception NN cord-010398-5wot7tix 333 2 : : : cord-010398-5wot7tix 334 1 The the DT cord-010398-5wot7tix 334 2 sense sense NN cord-010398-5wot7tix 334 3 of of IN cord-010398-5wot7tix 334 4 the the DT cord-010398-5wot7tix 334 5 physiological physiological JJ cord-010398-5wot7tix 334 6 condition condition NN cord-010398-5wot7tix 334 7 of of IN cord-010398-5wot7tix 334 8 the the DT cord-010398-5wot7tix 334 9 body body NN cord-010398-5wot7tix 334 10 Metabolic metabolic JJ cord-010398-5wot7tix 334 11 and and CC cord-010398-5wot7tix 334 12 cardiovascular cardiovascular JJ cord-010398-5wot7tix 334 13 effects effect NNS cord-010398-5wot7tix 334 14 of of IN cord-010398-5wot7tix 334 15 a a DT cord-010398-5wot7tix 334 16 progressive progressive JJ cord-010398-5wot7tix 334 17 exercise exercise NN cord-010398-5wot7tix 334 18 test test NN cord-010398-5wot7tix 334 19 in in IN cord-010398-5wot7tix 334 20 patients patient NNS cord-010398-5wot7tix 334 21 with with IN cord-010398-5wot7tix 334 22 chronic chronic JJ cord-010398-5wot7tix 334 23 fatigue fatigue NN cord-010398-5wot7tix 334 24 syndrome syndrome NN cord-010398-5wot7tix 334 25 Increased increase VBN cord-010398-5wot7tix 334 26 concentrations concentration NNS cord-010398-5wot7tix 334 27 of of IN cord-010398-5wot7tix 334 28 nerve nerve NN cord-010398-5wot7tix 334 29 growth growth NN cord-010398-5wot7tix 334 30 factor factor NN cord-010398-5wot7tix 334 31 in in IN cord-010398-5wot7tix 334 32 cerebrospinal cerebrospinal JJ cord-010398-5wot7tix 334 33 fluid fluid NN cord-010398-5wot7tix 334 34 of of IN cord-010398-5wot7tix 334 35 patients patient NNS cord-010398-5wot7tix 334 36 with with IN cord-010398-5wot7tix 334 37 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 334 38 Increased increase VBN cord-010398-5wot7tix 334 39 levels level NNS cord-010398-5wot7tix 334 40 of of IN cord-010398-5wot7tix 334 41 neurotrophins neurotrophin NNS cord-010398-5wot7tix 334 42 are be VBP cord-010398-5wot7tix 334 43 not not RB cord-010398-5wot7tix 334 44 specific specific JJ cord-010398-5wot7tix 334 45 for for IN cord-010398-5wot7tix 334 46 chronic chronic JJ cord-010398-5wot7tix 334 47 migraine migraine NN cord-010398-5wot7tix 334 48 : : : cord-010398-5wot7tix 335 1 Evidence evidence NN cord-010398-5wot7tix 335 2 from from IN cord-010398-5wot7tix 335 3 primary primary JJ cord-010398-5wot7tix 335 4 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 335 5 syndrome syndrome NN cord-010398-5wot7tix 335 6 Elevated elevated JJ cord-010398-5wot7tix 335 7 cerebrospinal cerebrospinal JJ cord-010398-5wot7tix 335 8 fluid fluid NN cord-010398-5wot7tix 335 9 levels level NNS cord-010398-5wot7tix 335 10 of of IN cord-010398-5wot7tix 335 11 substance substance NN cord-010398-5wot7tix 335 12 P p NN cord-010398-5wot7tix 335 13 in in IN cord-010398-5wot7tix 335 14 patients patient NNS cord-010398-5wot7tix 335 15 with with IN cord-010398-5wot7tix 335 16 the the DT cord-010398-5wot7tix 335 17 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 335 18 syndrome syndrome NN cord-010398-5wot7tix 335 19 Neurochemical Neurochemical NNP cord-010398-5wot7tix 335 20 pathogenesis pathogenesis NN cord-010398-5wot7tix 335 21 of of IN cord-010398-5wot7tix 335 22 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 335 23 Decreased decrease VBD cord-010398-5wot7tix 335 24 central central JJ cord-010398-5wot7tix 335 25 mu mu NN cord-010398-5wot7tix 335 26 - - JJ cord-010398-5wot7tix 335 27 opioid opioid JJ cord-010398-5wot7tix 335 28 receptor receptor NN cord-010398-5wot7tix 335 29 availability availability NN cord-010398-5wot7tix 335 30 in in IN cord-010398-5wot7tix 335 31 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 335 32 Cerebrospinal cerebrospinal NN cord-010398-5wot7tix 335 33 fluid fluid JJ cord-010398-5wot7tix 335 34 levels level NNS cord-010398-5wot7tix 335 35 of of IN cord-010398-5wot7tix 335 36 opioid opioid JJ cord-010398-5wot7tix 335 37 peptides peptide NNS cord-010398-5wot7tix 335 38 in in IN cord-010398-5wot7tix 335 39 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 335 40 and and CC cord-010398-5wot7tix 335 41 chronic chronic JJ cord-010398-5wot7tix 335 42 low low JJ cord-010398-5wot7tix 335 43 back back NN cord-010398-5wot7tix 335 44 pain pain NN cord-010398-5wot7tix 336 1 Why why WRB cord-010398-5wot7tix 336 2 stress stress NN cord-010398-5wot7tix 336 3 is be VBZ cord-010398-5wot7tix 336 4 bad bad JJ cord-010398-5wot7tix 336 5 for for IN cord-010398-5wot7tix 336 6 your -PRON- PRP$ cord-010398-5wot7tix 336 7 brain brain NN cord-010398-5wot7tix 337 1 The the DT cord-010398-5wot7tix 337 2 concepts concept NNS cord-010398-5wot7tix 337 3 of of IN cord-010398-5wot7tix 337 4 stress stress NN cord-010398-5wot7tix 337 5 and and CC cord-010398-5wot7tix 337 6 stress stress NN cord-010398-5wot7tix 337 7 system system NN cord-010398-5wot7tix 337 8 disorders disorder NNS cord-010398-5wot7tix 337 9 . . . cord-010398-5wot7tix 338 1 Overview overview NN cord-010398-5wot7tix 338 2 of of IN cord-010398-5wot7tix 338 3 physical physical JJ cord-010398-5wot7tix 338 4 and and CC cord-010398-5wot7tix 338 5 behavioral behavioral JJ cord-010398-5wot7tix 338 6 homeostasis homeostasis NN cord-010398-5wot7tix 338 7 Predicting predict VBG cord-010398-5wot7tix 338 8 chronic chronic JJ cord-010398-5wot7tix 338 9 symptoms symptom NNS cord-010398-5wot7tix 338 10 after after IN cord-010398-5wot7tix 338 11 an an DT cord-010398-5wot7tix 338 12 acute acute JJ cord-010398-5wot7tix 338 13 " " `` cord-010398-5wot7tix 338 14 stressor"-lessons stressor"-lesson NNS cord-010398-5wot7tix 338 15 learned learn VBN cord-010398-5wot7tix 338 16 from from IN cord-010398-5wot7tix 338 17 3 3 CD cord-010398-5wot7tix 338 18 medical medical JJ cord-010398-5wot7tix 338 19 conditions condition NNS cord-010398-5wot7tix 338 20 Unexplained unexplained JJ cord-010398-5wot7tix 338 21 symptoms symptom NNS cord-010398-5wot7tix 338 22 after after IN cord-010398-5wot7tix 338 23 terrorism terrorism NN cord-010398-5wot7tix 338 24 and and CC cord-010398-5wot7tix 338 25 war war NN cord-010398-5wot7tix 338 26 : : : cord-010398-5wot7tix 339 1 An an DT cord-010398-5wot7tix 339 2 expert expert JJ cord-010398-5wot7tix 339 3 consensus consensus NN cord-010398-5wot7tix 339 4 statement statement NN cord-010398-5wot7tix 339 5 Altered alter VBD cord-010398-5wot7tix 339 6 pituitary pituitary NN cord-010398-5wot7tix 339 7 - - HYPH cord-010398-5wot7tix 339 8 adrenal adrenal NN cord-010398-5wot7tix 339 9 axis axis NN cord-010398-5wot7tix 339 10 responses response NNS cord-010398-5wot7tix 339 11 to to IN cord-010398-5wot7tix 339 12 provocative provocative JJ cord-010398-5wot7tix 339 13 challenge challenge NN cord-010398-5wot7tix 339 14 tests test NNS cord-010398-5wot7tix 339 15 in in IN cord-010398-5wot7tix 339 16 adult adult NN cord-010398-5wot7tix 339 17 survivors survivor NNS cord-010398-5wot7tix 339 18 of of IN cord-010398-5wot7tix 339 19 childhood childhood NN cord-010398-5wot7tix 339 20 abuse abuse NN cord-010398-5wot7tix 339 21 Hypothalamic Hypothalamic NNP cord-010398-5wot7tix 339 22 - - HYPH cord-010398-5wot7tix 339 23 pituitaryadrenal pituitaryadrenal NNP cord-010398-5wot7tix 339 24 axis axis NN cord-010398-5wot7tix 339 25 perturbations perturbation NNS cord-010398-5wot7tix 339 26 in in IN cord-010398-5wot7tix 339 27 patients patient NNS cord-010398-5wot7tix 339 28 with with IN cord-010398-5wot7tix 339 29 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 339 30 Evidence evidence NN cord-010398-5wot7tix 339 31 for for IN cord-010398-5wot7tix 339 32 and and CC cord-010398-5wot7tix 339 33 pathophysiologic pathophysiologic JJ cord-010398-5wot7tix 339 34 implications implication NNS cord-010398-5wot7tix 339 35 of of IN cord-010398-5wot7tix 339 36 hypothalamic hypothalamic JJ cord-010398-5wot7tix 339 37 - - HYPH cord-010398-5wot7tix 339 38 pituitary pituitary NN cord-010398-5wot7tix 339 39 - - HYPH cord-010398-5wot7tix 339 40 adrenal adrenal NN cord-010398-5wot7tix 339 41 axis axis NN cord-010398-5wot7tix 339 42 dysregulation dysregulation NN cord-010398-5wot7tix 339 43 in in IN cord-010398-5wot7tix 339 44 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 339 45 and and CC cord-010398-5wot7tix 339 46 chronic chronic JJ cord-010398-5wot7tix 339 47 fatigue fatigue NN cord-010398-5wot7tix 340 1 syndrome syndrome NN cord-010398-5wot7tix 340 2 Electrodermal Electrodermal NNP cord-010398-5wot7tix 340 3 and and CC cord-010398-5wot7tix 340 4 microcirculatory microcirculatory JJ cord-010398-5wot7tix 340 5 activity activity NN cord-010398-5wot7tix 340 6 in in IN cord-010398-5wot7tix 340 7 patients patient NNS cord-010398-5wot7tix 340 8 with with IN cord-010398-5wot7tix 340 9 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 340 10 during during IN cord-010398-5wot7tix 340 11 baseline baseline NN cord-010398-5wot7tix 340 12 , , , cord-010398-5wot7tix 340 13 acoustic acoustic JJ cord-010398-5wot7tix 340 14 stimulation stimulation NN cord-010398-5wot7tix 340 15 and and CC cord-010398-5wot7tix 340 16 cold cold JJ cord-010398-5wot7tix 340 17 pressor pressor NN cord-010398-5wot7tix 340 18 tests test NNS cord-010398-5wot7tix 340 19 Reduced reduce VBN cord-010398-5wot7tix 340 20 hypothalamic hypothalamic JJ cord-010398-5wot7tix 340 21 - - HYPH cord-010398-5wot7tix 340 22 pituitary pituitary NN cord-010398-5wot7tix 340 23 and and CC cord-010398-5wot7tix 340 24 sympathoadrenal sympathoadrenal JJ cord-010398-5wot7tix 340 25 responses response NNS cord-010398-5wot7tix 340 26 to to IN cord-010398-5wot7tix 340 27 hypoglycemia hypoglycemia NN cord-010398-5wot7tix 340 28 in in IN cord-010398-5wot7tix 340 29 women woman NNS cord-010398-5wot7tix 340 30 with with IN cord-010398-5wot7tix 340 31 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 340 32 syndrome syndrome NN cord-010398-5wot7tix 340 33 Circadian Circadian NNP cord-010398-5wot7tix 340 34 studies study NNS cord-010398-5wot7tix 340 35 of of IN cord-010398-5wot7tix 340 36 autonomic autonomic JJ cord-010398-5wot7tix 340 37 nervous nervous JJ cord-010398-5wot7tix 340 38 balance balance NN cord-010398-5wot7tix 340 39 in in IN cord-010398-5wot7tix 340 40 patients patient NNS cord-010398-5wot7tix 340 41 with with IN cord-010398-5wot7tix 340 42 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 340 43 : : : cord-010398-5wot7tix 341 1 A a DT cord-010398-5wot7tix 341 2 heart heart NN cord-010398-5wot7tix 341 3 rate rate NN cord-010398-5wot7tix 341 4 variability variability NN cord-010398-5wot7tix 341 5 analysis analysis NN cord-010398-5wot7tix 341 6 Autonomic autonomic JJ cord-010398-5wot7tix 341 7 dysfunction dysfunction NN cord-010398-5wot7tix 341 8 in in IN cord-010398-5wot7tix 341 9 patients patient NNS cord-010398-5wot7tix 341 10 with with IN cord-010398-5wot7tix 341 11 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 341 12 : : : cord-010398-5wot7tix 342 1 Application application NN cord-010398-5wot7tix 342 2 of of IN cord-010398-5wot7tix 342 3 power power NN cord-010398-5wot7tix 342 4 spectral spectral JJ cord-010398-5wot7tix 342 5 analysis analysis NN cord-010398-5wot7tix 342 6 of of IN cord-010398-5wot7tix 342 7 heart heart NN cord-010398-5wot7tix 342 8 rate rate NN cord-010398-5wot7tix 342 9 variability variability NN cord-010398-5wot7tix 342 10 Childhood Childhood NNP cord-010398-5wot7tix 342 11 trauma trauma NN cord-010398-5wot7tix 342 12 and and CC cord-010398-5wot7tix 342 13 risk risk NN cord-010398-5wot7tix 342 14 for for IN cord-010398-5wot7tix 342 15 chronic chronic JJ cord-010398-5wot7tix 342 16 fatigue fatigue NN cord-010398-5wot7tix 342 17 syndrome syndrome NN cord-010398-5wot7tix 342 18 : : : cord-010398-5wot7tix 342 19 Association Association NNP cord-010398-5wot7tix 342 20 with with IN cord-010398-5wot7tix 342 21 neuroendocrine neuroendocrine JJ cord-010398-5wot7tix 342 22 dysfunction dysfunction NN cord-010398-5wot7tix 343 1 Combined combined JJ cord-010398-5wot7tix 343 2 dexamethasone dexamethasone NN cord-010398-5wot7tix 343 3 / / SYM cord-010398-5wot7tix 343 4 corticotropin corticotropin NN cord-010398-5wot7tix 343 5 - - HYPH cord-010398-5wot7tix 343 6 releasing release VBG cord-010398-5wot7tix 343 7 factor factor NN cord-010398-5wot7tix 343 8 test test NN cord-010398-5wot7tix 343 9 in in IN cord-010398-5wot7tix 343 10 chronic chronic JJ cord-010398-5wot7tix 343 11 fatigue fatigue NN cord-010398-5wot7tix 343 12 syndrome syndrome NN cord-010398-5wot7tix 343 13 Cerebrospinal cerebrospinal NN cord-010398-5wot7tix 343 14 fluid fluid NN cord-010398-5wot7tix 343 15 corticotropin corticotropin NN cord-010398-5wot7tix 343 16 - - HYPH cord-010398-5wot7tix 343 17 releasing release VBG cord-010398-5wot7tix 343 18 factor factor NN cord-010398-5wot7tix 343 19 concentration concentration NN cord-010398-5wot7tix 343 20 is be VBZ cord-010398-5wot7tix 343 21 associated associate VBN cord-010398-5wot7tix 343 22 with with IN cord-010398-5wot7tix 343 23 pain pain NN cord-010398-5wot7tix 343 24 but but CC cord-010398-5wot7tix 343 25 not not RB cord-010398-5wot7tix 343 26 fatigue fatigue NN cord-010398-5wot7tix 343 27 symptoms symptom NNS cord-010398-5wot7tix 343 28 in in IN cord-010398-5wot7tix 343 29 patients patient NNS cord-010398-5wot7tix 343 30 with with IN cord-010398-5wot7tix 343 31 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 343 32 Momentary momentary JJ cord-010398-5wot7tix 343 33 relationship relationship NN cord-010398-5wot7tix 343 34 between between IN cord-010398-5wot7tix 343 35 cortisol cortisol NN cord-010398-5wot7tix 343 36 secretion secretion NN cord-010398-5wot7tix 343 37 and and CC cord-010398-5wot7tix 343 38 symptoms symptom NNS cord-010398-5wot7tix 343 39 in in IN cord-010398-5wot7tix 343 40 patients patient NNS cord-010398-5wot7tix 343 41 with with IN cord-010398-5wot7tix 343 42 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 343 43 Moderation moderation NN cord-010398-5wot7tix 343 44 of of IN cord-010398-5wot7tix 343 45 psychosocial psychosocial JJ cord-010398-5wot7tix 343 46 risk risk NN cord-010398-5wot7tix 343 47 factors factor NNS cord-010398-5wot7tix 343 48 through through IN cord-010398-5wot7tix 343 49 dysfunction dysfunction NN cord-010398-5wot7tix 343 50 of of IN cord-010398-5wot7tix 343 51 the the DT cord-010398-5wot7tix 343 52 hypothalamic hypothalamic JJ cord-010398-5wot7tix 343 53 - - HYPH cord-010398-5wot7tix 343 54 pituitary pituitary NN cord-010398-5wot7tix 343 55 - - HYPH cord-010398-5wot7tix 343 56 adrenal adrenal NN cord-010398-5wot7tix 343 57 stress stress NN cord-010398-5wot7tix 343 58 axis axis NN cord-010398-5wot7tix 343 59 in in IN cord-010398-5wot7tix 343 60 the the DT cord-010398-5wot7tix 343 61 onset onset NN cord-010398-5wot7tix 343 62 of of IN cord-010398-5wot7tix 343 63 chronic chronic JJ cord-010398-5wot7tix 343 64 widespread widespread JJ cord-010398-5wot7tix 343 65 musculoskeletal musculoskeletal JJ cord-010398-5wot7tix 343 66 pain pain NN cord-010398-5wot7tix 343 67 : : : cord-010398-5wot7tix 343 68 Findings finding NNS cord-010398-5wot7tix 343 69 of of IN cord-010398-5wot7tix 343 70 a a DT cord-010398-5wot7tix 343 71 population population NN cord-010398-5wot7tix 343 72 - - HYPH cord-010398-5wot7tix 343 73 based base VBN cord-010398-5wot7tix 343 74 prospective prospective JJ cord-010398-5wot7tix 343 75 cohort cohort NN cord-010398-5wot7tix 343 76 study study NN cord-010398-5wot7tix 343 77 Perceived Perceived NNP cord-010398-5wot7tix 343 78 physical physical JJ cord-010398-5wot7tix 343 79 and and CC cord-010398-5wot7tix 343 80 emotional emotional JJ cord-010398-5wot7tix 343 81 trauma trauma NN cord-010398-5wot7tix 343 82 as as IN cord-010398-5wot7tix 343 83 precipitating precipitate VBG cord-010398-5wot7tix 343 84 events event NNS cord-010398-5wot7tix 343 85 in in IN cord-010398-5wot7tix 343 86 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 343 87 . . . cord-010398-5wot7tix 344 1 Associations association NNS cord-010398-5wot7tix 344 2 with with IN cord-010398-5wot7tix 344 3 health health NN cord-010398-5wot7tix 344 4 care care NN cord-010398-5wot7tix 344 5 seeking seeking NN cord-010398-5wot7tix 344 6 and and CC cord-010398-5wot7tix 344 7 disability disability NN cord-010398-5wot7tix 344 8 status status NN cord-010398-5wot7tix 344 9 but but CC cord-010398-5wot7tix 344 10 not not RB cord-010398-5wot7tix 344 11 pain pain NN cord-010398-5wot7tix 344 12 severity severity NN cord-010398-5wot7tix 344 13 Sexual sexual JJ cord-010398-5wot7tix 344 14 and and CC cord-010398-5wot7tix 344 15 physical physical JJ cord-010398-5wot7tix 344 16 abuse abuse NN cord-010398-5wot7tix 344 17 in in IN cord-010398-5wot7tix 344 18 women woman NNS cord-010398-5wot7tix 344 19 with with IN cord-010398-5wot7tix 344 20 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 344 21 : : : cord-010398-5wot7tix 344 22 Association Association NNP cord-010398-5wot7tix 344 23 with with IN cord-010398-5wot7tix 344 24 outpatient outpatient NN cord-010398-5wot7tix 344 25 health health NN cord-010398-5wot7tix 344 26 care care NN cord-010398-5wot7tix 344 27 utilization utilization NN cord-010398-5wot7tix 344 28 and and CC cord-010398-5wot7tix 344 29 pain pain NN cord-010398-5wot7tix 344 30 medication medication NN cord-010398-5wot7tix 344 31 usage usage NN cord-010398-5wot7tix 344 32 Sexual sexual JJ cord-010398-5wot7tix 344 33 and and CC cord-010398-5wot7tix 344 34 physical physical JJ cord-010398-5wot7tix 344 35 abuse abuse NN cord-010398-5wot7tix 344 36 in in IN cord-010398-5wot7tix 344 37 women woman NNS cord-010398-5wot7tix 344 38 with with IN cord-010398-5wot7tix 344 39 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 344 40 syndrome syndrome NN cord-010398-5wot7tix 344 41 Sexual sexual JJ cord-010398-5wot7tix 344 42 and and CC cord-010398-5wot7tix 344 43 physical physical JJ cord-010398-5wot7tix 344 44 abuse abuse NN cord-010398-5wot7tix 344 45 and and CC cord-010398-5wot7tix 344 46 gastrointestinal gastrointestinal JJ cord-010398-5wot7tix 344 47 illness illness NN cord-010398-5wot7tix 345 1 Does do VBZ cord-010398-5wot7tix 345 2 hypocortisolism hypocortisolism NN cord-010398-5wot7tix 345 3 predict predict VB cord-010398-5wot7tix 345 4 a a DT cord-010398-5wot7tix 345 5 poor poor JJ cord-010398-5wot7tix 345 6 response response NN cord-010398-5wot7tix 345 7 to to IN cord-010398-5wot7tix 345 8 cognitive cognitive JJ cord-010398-5wot7tix 345 9 behavioural behavioural JJ cord-010398-5wot7tix 345 10 therapy therapy NN cord-010398-5wot7tix 345 11 in in IN cord-010398-5wot7tix 345 12 chronic chronic JJ cord-010398-5wot7tix 345 13 fatigue fatigue NN cord-010398-5wot7tix 345 14 syndrome syndrome NN cord-010398-5wot7tix 346 1 As as RB cord-010398-5wot7tix 346 2 good good JJ cord-010398-5wot7tix 346 3 as as IN cord-010398-5wot7tix 346 4 it -PRON- PRP cord-010398-5wot7tix 346 5 gets get VBZ cord-010398-5wot7tix 346 6 ? ? . cord-010398-5wot7tix 347 1 A a DT cord-010398-5wot7tix 347 2 meta meta JJ cord-010398-5wot7tix 347 3 - - HYPH cord-010398-5wot7tix 347 4 analysis analysis NN cord-010398-5wot7tix 347 5 and and CC cord-010398-5wot7tix 347 6 systematic systematic JJ cord-010398-5wot7tix 347 7 review review NN cord-010398-5wot7tix 347 8 of of IN cord-010398-5wot7tix 347 9 methodological methodological JJ cord-010398-5wot7tix 347 10 quality quality NN cord-010398-5wot7tix 347 11 of of IN cord-010398-5wot7tix 347 12 heart heart NN cord-010398-5wot7tix 347 13 rate rate NN cord-010398-5wot7tix 347 14 variability variability NN cord-010398-5wot7tix 347 15 studies study NNS cord-010398-5wot7tix 347 16 in in IN cord-010398-5wot7tix 347 17 functional functional JJ cord-010398-5wot7tix 347 18 somatic somatic JJ cord-010398-5wot7tix 347 19 disorders disorder NNS cord-010398-5wot7tix 347 20 Epidemiology Epidemiology NNP cord-010398-5wot7tix 347 21 of of IN cord-010398-5wot7tix 347 22 chronic chronic JJ cord-010398-5wot7tix 347 23 musculoskeletal musculoskeletal JJ cord-010398-5wot7tix 347 24 pain pain NN cord-010398-5wot7tix 347 25 Resistance resistance NN cord-010398-5wot7tix 347 26 exercise exercise NN cord-010398-5wot7tix 347 27 training training NN cord-010398-5wot7tix 347 28 improves improve VBZ cord-010398-5wot7tix 347 29 heart heart NN cord-010398-5wot7tix 347 30 rate rate NN cord-010398-5wot7tix 347 31 variability variability NN cord-010398-5wot7tix 347 32 in in IN cord-010398-5wot7tix 347 33 women woman NNS cord-010398-5wot7tix 347 34 with with IN cord-010398-5wot7tix 347 35 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 347 36 POTS pot NNS cord-010398-5wot7tix 347 37 versus versus IN cord-010398-5wot7tix 347 38 deconditioning deconditione VBG cord-010398-5wot7tix 347 39 : : : cord-010398-5wot7tix 347 40 The the DT cord-010398-5wot7tix 347 41 same same JJ cord-010398-5wot7tix 347 42 or or CC cord-010398-5wot7tix 347 43 different different JJ cord-010398-5wot7tix 347 44 ? ? . cord-010398-5wot7tix 348 1 Chronic chronic JJ cord-010398-5wot7tix 348 2 fatigue fatigue NN cord-010398-5wot7tix 348 3 syndrome syndrome NN cord-010398-5wot7tix 348 4 : : : cord-010398-5wot7tix 349 1 Illness illness NN cord-010398-5wot7tix 349 2 severity severity NN cord-010398-5wot7tix 349 3 , , , cord-010398-5wot7tix 349 4 sedentary sedentary JJ cord-010398-5wot7tix 349 5 lifestyle lifestyle NN cord-010398-5wot7tix 349 6 , , , cord-010398-5wot7tix 349 7 blood blood NN cord-010398-5wot7tix 349 8 volume volume NN cord-010398-5wot7tix 349 9 and and CC cord-010398-5wot7tix 349 10 evidence evidence NN cord-010398-5wot7tix 349 11 of of IN cord-010398-5wot7tix 349 12 diminished diminished JJ cord-010398-5wot7tix 349 13 cardiac cardiac JJ cord-010398-5wot7tix 349 14 function function NN cord-010398-5wot7tix 349 15 Chronic chronic JJ cord-010398-5wot7tix 349 16 widespread widespread JJ cord-010398-5wot7tix 349 17 pain pain NN cord-010398-5wot7tix 349 18 and and CC cord-010398-5wot7tix 349 19 its -PRON- PRP$ cord-010398-5wot7tix 349 20 comorbidities comorbiditie NNS cord-010398-5wot7tix 349 21 : : : cord-010398-5wot7tix 349 22 A a DT cord-010398-5wot7tix 349 23 population population NN cord-010398-5wot7tix 349 24 - - HYPH cord-010398-5wot7tix 349 25 based base VBN cord-010398-5wot7tix 349 26 study study NN cord-010398-5wot7tix 349 27 Importance importance NN cord-010398-5wot7tix 349 28 of of IN cord-010398-5wot7tix 349 29 genetic genetic JJ cord-010398-5wot7tix 349 30 influences influence NNS cord-010398-5wot7tix 349 31 on on IN cord-010398-5wot7tix 349 32 chronic chronic JJ cord-010398-5wot7tix 349 33 widespread widespread JJ cord-010398-5wot7tix 349 34 pain pain NN cord-010398-5wot7tix 349 35 Coping cope VBG cord-010398-5wot7tix 349 36 strategies strategy NNS cord-010398-5wot7tix 349 37 in in IN cord-010398-5wot7tix 349 38 twins twin NNS cord-010398-5wot7tix 349 39 with with IN cord-010398-5wot7tix 349 40 chronic chronic JJ cord-010398-5wot7tix 349 41 fatigue fatigue NN cord-010398-5wot7tix 349 42 and and CC cord-010398-5wot7tix 349 43 chronic chronic JJ cord-010398-5wot7tix 349 44 fatigue fatigue NN cord-010398-5wot7tix 349 45 syndrome syndrome NN cord-010398-5wot7tix 350 1 A a DT cord-010398-5wot7tix 350 2 twin twin JJ cord-010398-5wot7tix 350 3 study study NN cord-010398-5wot7tix 350 4 of of IN cord-010398-5wot7tix 350 5 posttraumatic posttraumatic JJ cord-010398-5wot7tix 350 6 stress stress NN cord-010398-5wot7tix 350 7 disorder disorder NN cord-010398-5wot7tix 350 8 symptoms symptom NNS cord-010398-5wot7tix 350 9 and and CC cord-010398-5wot7tix 350 10 chronic chronic JJ cord-010398-5wot7tix 350 11 widespread widespread JJ cord-010398-5wot7tix 350 12 pain pain NN cord-010398-5wot7tix 350 13 Power power NN cord-010398-5wot7tix 350 14 spectral spectral JJ cord-010398-5wot7tix 350 15 analysis analysis NN cord-010398-5wot7tix 350 16 of of IN cord-010398-5wot7tix 350 17 sleep sleep NN cord-010398-5wot7tix 350 18 EEG EEG NNP cord-010398-5wot7tix 350 19 in in IN cord-010398-5wot7tix 350 20 twins twin NNS cord-010398-5wot7tix 350 21 discordant discordant JJ cord-010398-5wot7tix 350 22 for for IN cord-010398-5wot7tix 350 23 chronic chronic JJ cord-010398-5wot7tix 350 24 fatigue fatigue NN cord-010398-5wot7tix 350 25 syndrome syndrome NN cord-010398-5wot7tix 351 1 The the DT cord-010398-5wot7tix 351 2 Chronic Chronic NNP cord-010398-5wot7tix 351 3 Fatigue Fatigue NNP cord-010398-5wot7tix 351 4 Twin Twin NNP cord-010398-5wot7tix 351 5 Registry Registry NNP cord-010398-5wot7tix 351 6 : : : cord-010398-5wot7tix 351 7 Method method NN cord-010398-5wot7tix 351 8 of of IN cord-010398-5wot7tix 351 9 construction construction NN cord-010398-5wot7tix 351 10 , , , cord-010398-5wot7tix 351 11 composition composition NN cord-010398-5wot7tix 351 12 , , , cord-010398-5wot7tix 351 13 and and CC cord-010398-5wot7tix 351 14 zygosity zygosity NN cord-010398-5wot7tix 351 15 assignment assignment NN cord-010398-5wot7tix 351 16 Twin Twin NNP cord-010398-5wot7tix 351 17 analyses analysis NNS cord-010398-5wot7tix 351 18 of of IN cord-010398-5wot7tix 351 19 fatigue fatigue NN cord-010398-5wot7tix 352 1 A a DT cord-010398-5wot7tix 352 2 review review NN cord-010398-5wot7tix 352 3 of of IN cord-010398-5wot7tix 352 4 its -PRON- PRP$ cord-010398-5wot7tix 352 5 pharmacological pharmacological JJ cord-010398-5wot7tix 352 6 properties property NNS cord-010398-5wot7tix 352 7 and and CC cord-010398-5wot7tix 352 8 therapeutic therapeutic JJ cord-010398-5wot7tix 352 9 use use NN cord-010398-5wot7tix 352 10 in in IN cord-010398-5wot7tix 352 11 chronic chronic JJ cord-010398-5wot7tix 352 12 pain pain NN cord-010398-5wot7tix 352 13 states state VBZ cord-010398-5wot7tix 352 14 Long long JJ cord-010398-5wot7tix 352 15 - - HYPH cord-010398-5wot7tix 352 16 term term NN cord-010398-5wot7tix 352 17 results result NNS cord-010398-5wot7tix 352 18 of of IN cord-010398-5wot7tix 352 19 amitriptyline amitriptyline JJ cord-010398-5wot7tix 352 20 treatment treatment NN cord-010398-5wot7tix 352 21 for for IN cord-010398-5wot7tix 352 22 interstitial interstitial JJ cord-010398-5wot7tix 352 23 cystitis cystitis NN cord-010398-5wot7tix 352 24 Antidepressants Antidepressants NNPS cord-010398-5wot7tix 352 25 as as IN cord-010398-5wot7tix 352 26 analgesics analgesic NNS cord-010398-5wot7tix 352 27 : : : cord-010398-5wot7tix 352 28 A a DT cord-010398-5wot7tix 352 29 review review NN cord-010398-5wot7tix 352 30 of of IN cord-010398-5wot7tix 352 31 randomized randomized JJ cord-010398-5wot7tix 352 32 controlled control VBN cord-010398-5wot7tix 352 33 trials trial NNS cord-010398-5wot7tix 352 34 Duloxetine Duloxetine NNP cord-010398-5wot7tix 352 35 and and CC cord-010398-5wot7tix 352 36 other other JJ cord-010398-5wot7tix 352 37 antidepressants antidepressant NNS cord-010398-5wot7tix 352 38 in in IN cord-010398-5wot7tix 352 39 the the DT cord-010398-5wot7tix 352 40 treatment treatment NN cord-010398-5wot7tix 352 41 of of IN cord-010398-5wot7tix 352 42 patients patient NNS cord-010398-5wot7tix 352 43 with with IN cord-010398-5wot7tix 352 44 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 352 45 Gabapentin Gabapentin NNP cord-010398-5wot7tix 352 46 in in IN cord-010398-5wot7tix 352 47 the the DT cord-010398-5wot7tix 352 48 treatment treatment NN cord-010398-5wot7tix 352 49 of of IN cord-010398-5wot7tix 352 50 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 352 51 : : : cord-010398-5wot7tix 352 52 A a DT cord-010398-5wot7tix 352 53 randomized randomized JJ cord-010398-5wot7tix 352 54 , , , cord-010398-5wot7tix 352 55 double double JJ cord-010398-5wot7tix 352 56 - - HYPH cord-010398-5wot7tix 352 57 blind blind JJ cord-010398-5wot7tix 352 58 , , , cord-010398-5wot7tix 352 59 placebocontrolled placebocontrolled JJ cord-010398-5wot7tix 352 60 , , , cord-010398-5wot7tix 352 61 multicenter multicenter JJ cord-010398-5wot7tix 352 62 trial trial NN cord-010398-5wot7tix 352 63 A a DT cord-010398-5wot7tix 352 64 double double JJ cord-010398-5wot7tix 352 65 - - HYPH cord-010398-5wot7tix 352 66 blind blind JJ cord-010398-5wot7tix 352 67 , , , cord-010398-5wot7tix 352 68 multicenter multicenter JJ cord-010398-5wot7tix 352 69 trial trial NN cord-010398-5wot7tix 352 70 comparing compare VBG cord-010398-5wot7tix 352 71 duloxetine duloxetine NNP cord-010398-5wot7tix 352 72 with with IN cord-010398-5wot7tix 352 73 placebo placebo NN cord-010398-5wot7tix 352 74 in in IN cord-010398-5wot7tix 352 75 the the DT cord-010398-5wot7tix 352 76 treatment treatment NN cord-010398-5wot7tix 352 77 of of IN cord-010398-5wot7tix 352 78 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 352 79 patients patient NNS cord-010398-5wot7tix 352 80 with with IN cord-010398-5wot7tix 352 81 or or CC cord-010398-5wot7tix 352 82 without without IN cord-010398-5wot7tix 352 83 major major JJ cord-010398-5wot7tix 352 84 depressive depressive JJ cord-010398-5wot7tix 352 85 disorder disorder NN cord-010398-5wot7tix 352 86 Duloxetine Duloxetine NNP cord-010398-5wot7tix 352 87 for for IN cord-010398-5wot7tix 352 88 the the DT cord-010398-5wot7tix 352 89 treatment treatment NN cord-010398-5wot7tix 352 90 of of IN cord-010398-5wot7tix 352 91 fibromyalgia fibromyalgia NN cord-010398-5wot7tix 352 92 in in IN cord-010398-5wot7tix 352 93 women woman NNS cord-010398-5wot7tix 352 94 : : : cord-010398-5wot7tix 352 95 Pooled pool VBN cord-010398-5wot7tix 352 96 results result NNS cord-010398-5wot7tix 352 97 from from IN cord-010398-5wot7tix 352 98 two two CD cord-010398-5wot7tix 352 99 randomized randomized JJ cord-010398-5wot7tix 352 100 , , , cord-010398-5wot7tix 352 101 placebo placebo NN cord-010398-5wot7tix 352 102 - - HYPH cord-010398-5wot7tix 352 103 controlled control VBN cord-010398-5wot7tix 352 104 clinical clinical JJ cord-010398-5wot7tix 352 105 trials trial NNS cord-010398-5wot7tix 352 106 Management Management NNP cord-010398-5wot7tix 352 107 of of IN cord-010398-5wot7tix 352 108 musculoskeletal musculoskeletal JJ cord-010398-5wot7tix 352 109 pain pain NN cord-010398-5wot7tix 352 110 Exercise exercise NN cord-010398-5wot7tix 352 111 in in IN cord-010398-5wot7tix 352 112 the the DT cord-010398-5wot7tix 352 113 prevention prevention NN cord-010398-5wot7tix 352 114 and and CC cord-010398-5wot7tix 352 115 treatment treatment NN cord-010398-5wot7tix 352 116 of of IN cord-010398-5wot7tix 352 117 chronic chronic JJ cord-010398-5wot7tix 352 118 disorders disorder NNS cord-010398-5wot7tix 352 119 Cognitive cognitive JJ cord-010398-5wot7tix 352 120 and and CC cord-010398-5wot7tix 352 121 behavioral behavioral JJ cord-010398-5wot7tix 352 122 approaches approach NNS cord-010398-5wot7tix 352 123 to to IN cord-010398-5wot7tix 352 124 chronic chronic JJ cord-010398-5wot7tix 352 125 pain pain NN cord-010398-5wot7tix 352 126 Physiological physiological JJ cord-010398-5wot7tix 352 127 cost cost NN cord-010398-5wot7tix 352 128 of of IN cord-010398-5wot7tix 352 129 walking walk VBG cord-010398-5wot7tix 352 130 in in IN cord-010398-5wot7tix 352 131 those those DT cord-010398-5wot7tix 352 132 with with IN cord-010398-5wot7tix 352 133 chronic chronic JJ cord-010398-5wot7tix 352 134 fatigue fatigue NN cord-010398-5wot7tix 352 135 syndrome syndrome NN cord-010398-5wot7tix 352 136 ( ( -LRB- cord-010398-5wot7tix 352 137 CFS CFS NNP cord-010398-5wot7tix 352 138 ) ) -RRB- cord-010398-5wot7tix 352 139 : : : cord-010398-5wot7tix 352 140 A a DT cord-010398-5wot7tix 352 141 case case NN cord-010398-5wot7tix 352 142 - - HYPH cord-010398-5wot7tix 352 143 control control NN cord-010398-5wot7tix 352 144 study study NN cord-010398-5wot7tix 352 145 Chronic Chronic NNP cord-010398-5wot7tix 352 146 fatigue fatigue NN cord-010398-5wot7tix 352 147 syndrome syndrome NN cord-010398-5wot7tix 352 148 : : : cord-010398-5wot7tix 352 149 An an DT cord-010398-5wot7tix 352 150 approach approach NN cord-010398-5wot7tix 352 151 combining combine VBG cord-010398-5wot7tix 352 152 self self NN cord-010398-5wot7tix 352 153 - - HYPH cord-010398-5wot7tix 352 154 management management NN cord-010398-5wot7tix 352 155 with with IN cord-010398-5wot7tix 352 156 graded grade VBN cord-010398-5wot7tix 352 157 exercise exercise NN cord-010398-5wot7tix 352 158 to to TO cord-010398-5wot7tix 352 159 avoid avoid VB cord-010398-5wot7tix 352 160 exacerbations exacerbation NNS cord-010398-5wot7tix 352 161 Moderate moderate JJ cord-010398-5wot7tix 352 162 exercise exercise NN cord-010398-5wot7tix 352 163 increases increase VBZ cord-010398-5wot7tix 352 164 expression expression NN cord-010398-5wot7tix 352 165 for for IN cord-010398-5wot7tix 352 166 sensory sensory JJ cord-010398-5wot7tix 352 167 , , , cord-010398-5wot7tix 352 168 adrenergic adrenergic NN cord-010398-5wot7tix 352 169 , , , cord-010398-5wot7tix 352 170 and and CC cord-010398-5wot7tix 352 171 immune immune JJ cord-010398-5wot7tix 352 172 genes gene NNS cord-010398-5wot7tix 352 173 in in IN cord-010398-5wot7tix 352 174 chronic chronic JJ cord-010398-5wot7tix 352 175 fatigue fatigue NN cord-010398-5wot7tix 352 176 syndrome syndrome NN cord-010398-5wot7tix 352 177 patients patient NNS cord-010398-5wot7tix 352 178 but but CC cord-010398-5wot7tix 352 179 not not RB cord-010398-5wot7tix 352 180 in in IN cord-010398-5wot7tix 352 181 normal normal JJ cord-010398-5wot7tix 352 182 subjects subject NNS