id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-259364-8zoav7b0	Xiao, Yire	Production of anti-Trichophyton rubrum egg yolk immunoglobulin and its therapeutic potential for treating dermatophytosis	2019-09-09		.txt	text/plain	4494	247	56	title: Production of anti-Trichophyton rubrum egg yolk immunoglobulin and its therapeutic potential for treating dermatophytosis The aim of this study was to estimate the therapeutic potential of specific egg yolk immunoglobulin (IgY) on dermatophytosis caused by Trichophyton rubrum. rubrum cell wall proteins IgY (anti-trCWP IgY) presented a certain degree of cross-reactivity with different fungi. In the in vitro and in vivo activity researches, Anti-trCWP IgY showed a significant dose-dependent growth inhibitory effect on T. To estimate the cross-reactivity (CR) of anti-trCWP IgY against other fungi, indirect ELISAs were performed by the use of antigens from different fungi according to the method described previously. rubrum and the protective effect of anti-trCWP IgY against dermatophytosis of experimentally infected mice. In our study, the cell wall proteins showed good immunogenicity, highest titer of anti-trCWP IgY reaching 1:16000. rubrum in a dose-dependent manner compared with IgY from unimmunized hens,and significantly reduced lesion scores of mice experimentally infected with T.	./cache/cord-259364-8zoav7b0.txt	./txt/cord-259364-8zoav7b0.txt