id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-340202-ikptxviu	Van Diep, Nguyen	US-like isolates of porcine epidemic diarrhea virus from Japanese outbreaks between 2013 and 2014	2015-12-02		.txt	text/plain	3770	191	56	Sequencing and phylogenic analyses of the partial spike gene and ORF3 of PEDV demonstrated that all prevailing Japanese PEDV isolates belonged to novel genotypes that differed from previously reported strains and the two PEDV vaccine strains currently being used in Japan. Unlike vaccine strains, all prevailing field PEDV isolates in Japan were found to have a number of amino acid differences in the neutralizing epitope domain, COE, which may affect antigenicity and vaccine efficacy. This study aimed to evaluate the genetic characteristics and molecular epidemiology of the emergent Japanese PEDV isolates using genome analysis and phylogenetic analysis of the partial S gene and ORF3. To investigate the heterogeneity of the recent Japanese isolates and their genetic relationship with modified live vaccines, in addition to 2 PEDV vaccine strains (P5-V and 96-P4C6) used in Japan, representative isolates were selected for sequencing of the partial S gene and full ORF3 gene.	./cache/cord-340202-ikptxviu.txt	./txt/cord-340202-ikptxviu.txt